Abstract：
:The evolution of anti-cancer chemotherapy has led to long duration treatments, which preferentially are given at home, with the participation of the general practitionner (G.P.). The indications and general supervision of these belong to the oncologist, so thus necessitates a coordinated effort between the many physicians. A postal inquiry has permitted the collection of the opinions of 169 G.P. (more than half of the consulted physicians) from the southwest of France, in the region depending on the Fondation Bergonié. Thus it was possible to establish the importance of this type of treatment for the majority of the G.P., the details of problems of practical application, and the value attached to the relationships with the oncologist, which need further development.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Hoerni B,Chauvergne J,Durand M,Lagarde Csubject
Has Abstractpub_date
1976-01-01 00:00:00pages
59-68issue
1eissn
0007-4551issn
1769-6917journal_volume
63pub_type
杂志文章abstract：BACKGROUND:Depression is an important symptom for many palliative care patients but is rarely identified. It's known to reduce quality of life and impact on palliation of physical symptom. These physical symptoms can be improved by an adequate treatment of depression. Many depressed cancer patients are not treated due ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2011.1310
更新日期：2011-02-01 00:00:00
abstract：:Colorectal primary signet ring cell carcinoma (SRCC) is a rare entity accounting for nearly 1% of all colorectal carcinomas. It is an independent prognostic factor associated with less favorable outcome. This aggressiveness is mainly due to the intrinsic biology of these tumors. Here is an overview of the literature r...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1016/j.bulcan.2015.07.005
更新日期：2015-10-01 00:00:00
abstract：INTRODUCTION:Since the last cancer plan 2014-2019, the assessment of the impact of the disease on caregivers became essential. The quality of caregiving represents an important part of the patient's quality of life. The main objective was to describe the evolution of caregiver's attachment style during the first three ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/j.bulcan.2020.08.011
更新日期：2020-11-01 00:00:00
abstract：:Multifactorial resistance is the main mechanism of chemotherapy failure in cancers. Multidrug resistance (MDR) is related to the expression of a 170 kDa membrane glycoprotein, the so-called P-glycoprotein (P-gp). This protein is able to extrude drugs of various structures and mechanisms out of the cytoplasm. P-gp is a...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1996-08-01 00:00:00
abstract：:465 patients with broncho-pulmonary malignant tumors have been autopsied. Small cell carcinoma was diagnosed in 22.5 per cent of these patients. The histo-cytological variants of these tumors (lymphocytoid, polygonal, fusiform and polymorphic) had the same general characteristics (age, sex, survival) and a similar cli...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:The antiestrogen tamoxifen (TAM) has been successfully used to treat breast cancer expressing estrogen and progesterone receptors (ER+ and PR+). However, the development of antiestrogen resistance is frequently observed in patients following long-term treatment. To better understand the mechanism of action of TAM and ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:In 2003, there was 147,000 deaths attributed to cancer in France, 88,000 in men and 59,000 in women. Cancer mortality rates have been decreasing since 1987 in the male population and since the late 60's in the female population, the decrease is larger for the male population. This decrease is observed for most sites o...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:With over 70,000 patients treated worldwide, protontherapy has an evolution on their clinical applications and technological developments. The ballistic advantage of the Bragg peak gives the possibility of getting a high conformation of the dose distribution to the target volume. Protontherapy has accumulated a consid...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2010.1149
更新日期：2010-07-01 00:00:00
abstract：:Cancer patients are often moved inside the hospital to different examination clinics, such as radiology, CT scan, MRI... and to treatment clinics, such as radiotherapy. These transports induce important pain phenomena, not really recognized by professional teams. As these kinds of pains are expected and can be prevent...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2008.0638
更新日期：2008-05-01 00:00:00
abstract：:As soon as they get accepted into medical school, students find themselves facing numerous expectations: coping with tremendous study burden, competing with others for the best rank, completing internships and participating in the race for publishing are only to name a few. This big juggle makes it hard for the medica...
journal_title：Bulletin du cancer
pub_type： 社论
doi：10.1016/j.bulcan.2018.04.005
更新日期：2018-06-01 00:00:00
abstract：:Rapamycin (sirolimus) is a macrolide, related to cyclosporine with immunosuppressive properties and antiproliferative activity in various human tumor cells lines and tumor xenograft models. The cytosolic kinase mTOR which controls the initiation of the translation of messenger RNA is the main known target of rapamycin...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1999-10-01 00:00:00
abstract：:Angiogenesis plays an important role in the progression of tumors. This relationship has been described in several hematologic malignancies. Vascular endothelial growth factor and basic fibroblast growth factor are predictors of poor prognosis in leukemia and non Hodgkin's lymphoma. Bone marrow microvessels were found...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2007-07-01 00:00:00
abstract：:The authors report a case of endometrial carcinoma treated with tamoxifen introduced after normal initial uterine curettage. Based on recent experimental and clinical data, the importance of a gynecological follow-up in anti-estrogen therapy is emphasized. ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：:Colorectal cancer (CRC) is the second leading cause of cancer-related mortality in France. Recently, colorectal cancer subtyping consortium (CRCSC) identified 4 consensus molecular subtypes (CMS). CMS1 is enriched for CRC with deficient DNA mismatch repair system (dMMR) and tumors with mutated BRAF. Intriguingly, CMS1...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1016/S0007-4551(15)31220-0
更新日期：2015-06-01 00:00:00
abstract：:Leiomyosarcoma of the larynx is extremely rare, only 21 cases were reported in the literature. The authors report a personal case in a 26 years old patient treated by a total laryngectomy and analyse all cases of the literature. It comes in relative young man (42 years old) in regard to the others ORL localisations. T...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:Malnutrition is frequently observed in oncology. The consequences on patient survival, chemotherapy toxicities and quality of life need to be identified and treated appropriately. A set of tools are available that enable clinicians to diagnose and detect malnutrition. Each tool must consider three items: the patient's...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1016/j.bulcan.2016.06.003
更新日期：2016-09-01 00:00:00
abstract：AIM:Harvesting of the "sentinel lymph node" (SLN) as identified by lymphoscintigraphy (LSG) is becoming increasingly important in the staging of patients with malignant melanoma. The purpose of the current study was to determine whether the appearance time of the LSG had a prognostic value in predicting metastasis diss...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：INTRODUCTION:Surgical treatment of malignant primitive tumors of bone needs a precise preoperative assessment of tumor local extension. Joint involvement (JI) represents the most important finding to determine, for the choice of surgical procedure (intra- or extra-articular resection). OBJECTIVE:To determine the value...
journal_title：Bulletin du cancer
pub_type： 杂志文章,多中心研究
doi：10.1016/j.bulcan.2016.09.018
更新日期：2016-11-01 00:00:00
abstract：:The great majority of breast cancer cases are not associated with a mutated gene of high penetrance such as BRCA1, BRCA2 and TP53. Genes of low penetrance, frequently mutated in the general population, might play an important role in breast cancer development. The ATM gene, which encodes the ATM protein, mutated in th...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2001-07-01 00:00:00
abstract：BACKGROUND:The standard treatment in first line of advanced or metastatic urothelial bladder cancer (MBC) is the association of Gemcitabine and Cisplatin (GC). Avelumab, an anti-PD-L1 agent, has recently demonstrated efficacy. The objective is to evaluate the combination of these 3 agents. METHODS:This phase II random...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/S0007-4551(20)30280-0
更新日期：2020-06-01 00:00:00
abstract：:Announcing a cancer diagnosis, but also a relapse, a progression of the disease, or transition towards palliative care constitute particularly difficult communication issues for the patient as well as for the clinician, during the trajectory of care. The objectives of this article is to present the clinical stakes of ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2010.1197
更新日期：2010-10-01 00:00:00
abstract：:From 1970 to 1982, 79 cases of nasopharyngeal carcinomas were treated at the Regional Cancer Center of Lille (France). At the term of the study, it appears that patients of Central Europe origin have a rather high risk of NPC (17% of cases, that ethnic population representing about 8% of all superior aerodigestive tra...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Perioperative chemotherapy for gastric cancer is validated by two phase III studies. The impact of the preoperative neoadjuvant sequence is probably major in the benefit of this treatment. This chemotherapy increases the R0 resection without increasing either morbidity or mortality. Furthermore, it reduces local and s...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2010.1287
更新日期：2011-01-01 00:00:00
abstract：:This study is devoted to the analysis of the surgical treatment of cancer of the uterine cervix, stage III. Three circumstances are evaluated: - Stage III with urinary disease the purpose of the surgical treatment is most often to save the renal function;--Recurrences after radiotherapy where surgery is the only poss...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：INTRODUCTION:The treatment of chronic myeloid leukemia (CML) has been revolutionized by the advent of tyrosine kinase inhibitors. The results of the IRIS trial demonstrated the efficacy and long-term safety profile of Imatinib. The objective of our work is to report the results at 15 years of treatment of CML in chroni...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/j.bulcan.2020.05.013
更新日期：2020-09-01 00:00:00
abstract：:Two operational subdivisions of hereditary colorectal cancer susceptibility are those with and those without premalignant adenomatous colonic polyp expression. In both of these subdivisions, reliable biomarkers of gene carriage would be of value in patient management as we have previously emphasized. Consideration mus...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The first endoscopic gall-bladder ablation was performed in France, twenty years ago. NOTES (natural orifices transluminal endoscopic surgery) is a new step towards surgery leaving no scar. Is surgery's paradigm changing now ? This short study will focus on the epistemologic and ethical changes which have been generat...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2007.0518
更新日期：2007-12-01 00:00:00
abstract：:Taxoids and platinum derivatives display a true activity against many types of solid tumors. Their relatively non overlapping toxicity profiles and their different mechanisms of action made their combination attractive. Actually, the frequency and the severity of the toxicity appeared schedule-dependent. Thus, cisplat...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2000-08-01 00:00:00
abstract：:Glioblastoma multiforme still remains, at present, the most frequent and deadly primary malignant glioma in adult. Despite safer and larger neurosurgical resections, patients almost always relapse very close or inside the tumor bed. Since more than 20 years, radiation therapy (RT) continue delivering the same dose of ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2005-04-01 00:00:00
abstract：:Oncolor, the French regional cancer network of Lorraine, proposes clinical guidelines for the diagnosis, the treatment and the follow-up of cancers. In addition to paper documents, two computerized supports, a web site and the Kasimir software have been developed to make the use of these guidelines and their updating ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2003-04-01 00:00:00
