Early diagnosis of gastrointestinal cancer.

abstract：AIM:Harvesting of the "sentinel lymph node" (SLN) as identified by lymphoscintigraphy (LSG) is becoming increasingly important in the staging of patients with malignant melanoma. The purpose of the current study was to determine whether the appearance time of the LSG had a prognostic value in predicting metastasis diss...

journal_title：Bulletin du cancer

authors： Cammilleri S,Jacob T,Rojat-Habib MC,Hesse S,Berthet B,Giorgi R,Bonerandi JJ,Mundler O

更新日期：2004-07-01 00:00:00

abstract：:Innovation in radiotherapy should meet multiple challenges, both technically, biologically, clinically and socially. Scientific, technological and biological advances have resulted in major changes in the implementation, indications, and therapeutic index of radiotherapy over the last century. Based on technical innov...

journal_title：Bulletin du cancer

authors： Vial N,Vallard A,Jmour O,Rehailia-Blanchard A,Ben Mrad M,Trone JC,Daguenet E,Guy JB,Magné N

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Since the last cancer plan 2014-2019, the assessment of the impact of the disease on caregivers became essential. The quality of caregiving represents an important part of the patient's quality of life. The main objective was to describe the evolution of caregiver's attachment style during the first three ...

journal_title：Bulletin du cancer

authors： Bonnet M,Vadam F,Belot RA,Quibel C,Pozet A,Nerich V

更新日期：2020-11-01 00:00:00

abstract：:Two criteria are firstly used in the selection of new anticancer agents:--originality of the mechanism of action and significant experimental antitumor activity in an in vivo animal model. Murine tumors grafted in syngenic mice and human tumor xenografts implanted in nude mice are old models which continue to be widel...

journal_title：Bulletin du cancer

authors： Lavelle F

更新日期：1998-10-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is an uncommon neuro-endocrine tumor of the sun-exposed skin predominantly observed in white patients in the sixth decade of the life. In electron microscopy MCC characteristically contains dense core secretory granules. This tumor expresses both epithelial (keratins of low molecular weight...

journal_title：Bulletin du cancer

authors： Voog E,Blay JY

更新日期：1999-07-01 00:00:00

abstract：:We describe the psychological reactions after diagnosis and treatment of the malignant intraocular tumors: uveal melanoma and retinoblastoma. The chapter on uveal melanoma includes general consideration on the treatment of these tumors, the psychological effects on the patients, the professional and social problems, t...

journal_title：Bulletin du cancer

authors： Desjardins L,Delage M,Lumbroso L,Levy C,Doz F

更新日期：2001-11-01 00:00:00

abstract：:Multidrug resistant (MDR) phenotype is characterized by a defect in drug accumulation caused by overexpression of a transmembrane glycoprotein, the P-glycoprotein (P-gp). MDR phenotype can be characterized either with monoclonal antibodies raised against P-gp or with functional tests, most often based on the incorpora...

journal_title：Bulletin du cancer

authors： Lizard G,Maynadié M,Roignot P,Lizard-Nacol S,Poupon MF

更新日期：1995-03-01 00:00:00

abstract：INTRODUCTION:Few studies have explored the long-term occupational situation after cancer. The aim of our study were to study the employment status among long-term cancer survivors and to compare it to cancer-free controls from the general population at 5, 10 or 15 years after cancer diagnosis. METHODS:From data of a r...

journal_title：Bulletin du cancer

authors： Saim A,Gernier F,Licaj I,Rod J,Velten M,Klein D,Mercier M,Joly F

更新日期：2020-09-01 00:00:00

abstract：:Superficial bladder tumor defined as pTa, pT1 and pTis stage is one of the most common cancer disease in the world. Intravesical BCGtherapy represents the best treatment when combined with transurethral resection to prevent tumor recurrence or progression and to lengthen the interval between recurrence. The toxicity i...

journal_title：Bulletin du cancer

authors： Prapotnich D

更新日期：1998-02-01 00:00:00

abstract：:Neoadjuvant chemoradiotherapy is considered at the present time as the standard treatment of most T3-4 rectal cancer. In France a combination of radiotherapy (45 Gy/5 weeks) with concurrent capecitabine (1,600 mg/m2) is the most popular protocol. Randomized trials try to optimize this approach using new cytotoxic drug...

journal_title：Bulletin du cancer

authors： Gérard JP,Francois E,Deustch E,Rostom Y,Douar N,Benezery K,Milano G

更新日期：2009-03-01 00:00:00

abstract：:The clinico-pathological and epidemiological features of 119 cases of Kaposi's sarcoma diagnosed during the years 1979-1986 in the main pathology department of Rwanda are presented. Skin involvement (89%) was predominant with almost 70% of cutaneous lesions localised on the lower limbs; 11% of cases presented with ext...

journal_title：Bulletin du cancer

authors： Ngendahayo P,Mets T,Bugingo G,Parkin DM

更新日期：1989-01-01 00:00:00

abstract：:The treatment of metastatic melanoma is presently in complete revolution. Two molecules have recently been authorized for this indication. These treatments have a very different mechanism of action compared to previous chemotherapies. Vemurafenib is a targeted therapy, which blocks BRAF selectively. This molecule indu...

journal_title：Bulletin du cancer

authors： Mateus C,Robert C

更新日期：2012-06-01 00:00:00

abstract：:Brain metastases management is still controversial even though many trials are trying to define the respective roles of neurosurgery, whole-brain radiotherapy, single-dose stereotactic radiotherapy and fractionated stereotactic radiotherapy. In this article, we review data from trials that examine the role of radiosur...

journal_title：Bulletin du cancer

authors： Tanguy R,Métellus P,Mornex F,Mazeron JJ

更新日期：2013-01-01 00:00:00

abstract：:Propensity score, an indicator of the propensity to get one treatment among two (or more), is encountered in non randomized studies (prospective or retrospective). It is calculated after the research of predictive factors for treatment attribution, and corresponds to the probability to receive one of the treatments co...

journal_title：Bulletin du cancer

authors： Kwiatkowski F,Slim K,Verrelle P,Chamorey E,Kramar A

更新日期：2007-07-01 00:00:00

abstract：:BRCA is a tumor suppressor gene implicated in the major mechanisms of cellular stability in every type of cell. Its mutations are described in numerous cancers, mainly breast and ovarian in women. It was also found an increase of lifetime risk of pancreas, colon, prostate cancer or lymphoma in men carriers. We report ...

journal_title：Bulletin du cancer

authors： Girardstein-Boccara L,Mari V,Met-Domestici M,Burel-Vandenbos F,Berthet P,Paquis P,Frenay MP,Lebrun-Frenay C

更新日期：2014-09-01 00:00:00

abstract：:Oncolor, network in oncology in Lorraine, was born ten years ago, from a group of professionals in the field of oncology who worked closed together with regional administrative authorities. Oncolor was created with respect of equilibrium between the different regional partners avoiding struggle for power. Oncolor was ...

journal_title：Bulletin du cancer

authors： Bey P,Bouvier R,David M,Delena G,Garin H,Kessler Y,Klein I,Krakowski I,Lang MP,Leclercq JM,Level MC,Luron R,May I,Nabet M,Ruck S,Sommelet D,Theobald S,Unvois R,Walter S

更新日期：2004-07-01 00:00:00

abstract：:Malnutrition is common in oncology. However, it is often detected too late and nutritional support is sub-optimal. The patient's opinion, although often sought in therapeutic decisions in oncology, does not appear to be frequently taken into account in dietetic management. In NutriCancer2012 study, we interviewed pati...

journal_title：Bulletin du cancer

authors： Raynard B,Hébuterne X,Goldwasser F,Ait Hssain A,Dubray Longeras P,Barthélémy P,Rosso E,Phoutthasang V,Bories C,Digue L,Laharie D,Desport JC,Falkowski S,Lacau Saint Guily J,Gyan E

更新日期：2017-11-01 00:00:00

abstract：:In recent years, Internet has become an indispensable tool for all types of information. Its importance has increased in medicine and particularly in human malignancies. The data issued by the Internet are many and varied sources ranging from official websites to patient's blogs. HIV infection is an infection highly p...

journal_title：Bulletin du cancer

authors： Cluzeau T,Mounier N

更新日期：2010-10-01 00:00:00

abstract：:Surgical oncology requires an indispensable cultural and interdisciplinary approach of cancer. It needs a solid surgical formation combined with knowledges in biology, pathology, radiology, chemotherapy, and radiotherapy so oncologist surgeons are better able to define the limits of intervention according to the natur...

journal_title：Bulletin du cancer

authors： Bobin JY,Delay E,Rivoire M

更新日期：1995-01-01 00:00:00

abstract：:Hypoxic cell fraction was measured in a human tumour xenografted on two different animal species: mouse and rat. These results suggest that, while the Na11 tumour response to radiation depends on the host (nude mouse, nude rat), the proportion of hypoxic cells tested with the growth delay assay is independent of the h...

journal_title：Bulletin du cancer

authors： Guichard M,Chavaudra N,Malaise EP

更新日期：1989-01-01 00:00:00

abstract：:Docetaxel (Taxotère) has been developed in breast cancer during the last decade. First its activity in monotherapy was proven in metastatic setting after failure of anthracycline therapy. Then the association with anthracycline demonstrated substantial activity leading to its development in early stages of breast canc...

journal_title：Bulletin du cancer

authors： Diéras V,Girre V,Pierga JY,Laurence V,Piperno-Neumann S,Pouillart P

更新日期：2004-05-01 00:00:00

abstract：:Cancer patients frequently undergo imaging examinations to diagnosis but also to evaluate their responses to treatment. These patients are also at high risk of kidney impairment before considering the possible nephrotoxicity of their chemotherapy. In this context, it is overriding to know contrast agents induced risks...

journal_title：Bulletin du cancer

authors： Amet S,Deray G

更新日期：2012-03-01 00:00:00

abstract：:This review reports 3 of recently published molecular classifications of the 3 main gastro-intestinal cancers: gastric, pancreatic and colorectal adenocarcinoma. In colorectal adenocarcinoma, 6 independent classifications were combined to finally hold 4 molecular sub-groups, Consensus Molecular Subtypes (CMS 1-4), lin...

journal_title：Bulletin du cancer

authors： Dreyer C,Afchain P,Trouilloud I,André T

更新日期：2016-07-01 00:00:00

abstract：:Stereotactic radiation therapy, consisting in irradiating the tumor with a high dose per fraction, has a therapeutic potential because of excellent local control. This technique requires a high accuracy level in order to minimize the risk of normal tissue toxicity. Initially used for cerebral localization, the stereot...

journal_title：Bulletin du cancer

authors： Ayadi M,Ginestet C,Gassa F,Claude L,Mazeron JJ

更新日期：2010-07-01 00:00:00

abstract：:This survey, conducted in region Rhône-Alpes (France), aims to assess some data in thoracic oncology practice including availability of specialized equipments. This study is based on a questionnaire mailed to oncologists and pulmonologists in the region. Of 401 questionnaires, the response rate was 56%. Responses of 7...

journal_title：Bulletin du cancer

authors： Couraud S,Fournel P,Moro-Sibilot D,Pérol M,Souquet PJ

更新日期：2011-06-09 00:00:00

abstract：:Having to start chemotherapy during pregnancy remains a rare event. The decision to proceed this treatment relies on the drugs used, the time of exposure for the foetus and the gestational age at the time of exposure. As a matter of fact, the mutagenicity potential of the chosen medicine has to be known, and consequen...

journal_title：Bulletin du cancer

authors： Pautier P,Lhomme C,Morice P

更新日期：2002-09-01 00:00:00

abstract：:Treatment of patients with small-cell lung cancer (SCLC) remains disappointing despite high initial complete response rates. The dramatic initial chemosensitivity of tumor cells is frustrated by the early emergence of chemoresistant clonogenic cells, regardless of front line treatments. Although the dose relationship ...

journal_title：Bulletin du cancer

authors： Le Chevalier T,Le Cesne A,Arriagada R

更新日期：1995-01-01 00:00:00

abstract：:Doxifluridine, a new fluorouracil analog with a low myelosuppressive effect, has recently been subject to various disease-oriented, Phase II trials. For the present evaluation of drug tolerance, the Phase II data of 114 patients having received 376 doxifluridine cycles has been used. The treatment cycles consisted of ...

journal_title：Bulletin du cancer

authors： Winkelmann JJ,Alberto P,Mermillod B

更新日期：1990-01-01 00:00:00

abstract：:Recent progress in the field of molecular biology has allowed us to identify at least two different molecular mechanisms implicated in colorectal carcinogenesis (CRC): chromosomal instability (CIN) and genetic instability. Even though the two molecular mechanisms differ, their signalling pathways, implicated in malign...

journal_title：Bulletin du cancer

authors： Laurent-Puig P,Agostini J,Maley K

更新日期：2010-11-01 00:00:00

abstract：:Angiogenesis plays an important role in the progression of tumors. This relationship has been described in several hematologic malignancies. Vascular endothelial growth factor and basic fibroblast growth factor are predictors of poor prognosis in leukemia and non Hodgkin's lymphoma. Bone marrow microvessels were found...

journal_title：Bulletin du cancer

authors： Zini JM,Tobelem G

更新日期：2007-07-01 00:00:00