Abstract：
:Patients with advanced cancer often experience with physical impairment and loss of autonomy sometimes preceding inexorable death. It is that can emerge Suicidal ideation occasionally associated with suicidal attempt can arise in this particular context but also following the initial diagnostic talk and during all the stages of the disease. The risk is often considered twice higher in this patients'group compared to the general population and increases with advanced stages of the disease. Among patients with cancer, suicidal crisis can be expressed as part of a request for euthanasia, physician-assisted suicide and para suicide behaviors. Clues can help the clinician to identify early these vulnerable patients. Therefore, suicidal situations can emerge in the particular context of physical impairment, poor quality of life and poor control of physical symptoms (such as pain, tumoral localization in particular lung, head and neck, pancreas). The association of hopelessness and helplessness and a loss of control of the situation are strongly correlated with the expression of suicidal ideations. The presence of a confusional or psychomotor disinhibition with hallucinations, irrational thoughts and the absence of a libidinal object of investment have also to be taken into account. This suicidal crisis can be considered as a way for the patient to escape an intolerable situation (uncontrolled pain or other symptoms) and maintain self-control and decisional autonomy. Management of suicidal crisis in patients with cancer includes careful attention and legitimization of the patient's distress without inducing any guilt. Appropriate control of physical symptoms is warranted including screening and treating any mood disorder or any organic mental disorder. Treating associated anxiety and making sure that the patient's safety is under control are essential. Last but not the least, involving the whole treatment team is key in preventing transformation of the suicidal crisis into institutional crisis.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Lefetz C,Reich Msubject
Has Abstractpub_date
2006-07-01 00:00:00pages
709-13issue
7eissn
0007-4551issn
1769-6917journal_volume
93pub_type
杂志文章abstract：:The tolerance and the clinical and histological efficacy of a neoadjuvant chemotherapy FEC-HD including hematopoietic growth factors have been studied in 40 patients with stade II or III breast cancer between February 1991 and February 1997. Four courses were given, every 21 days, with 5-fluorouracil (750 mg/m2/day D1...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1999-02-01 00:00:00
abstract：:In medical oncology, how can we be sure that the right drug is being administered to the right patient at the right time? The implementation of quality assurance criteria is important in medical oncology, in order to ensure that the patient receives the best treatment safely. There is very little literature about qual...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2014.1968
更新日期：2014-05-01 00:00:00
abstract：:The discovery of oncogenes and tumor suppressors has established the original concept of cancer development based on a cascade of spontaneously occurring somatic mutations. It is now well known that genomes of cancer cells are deeply rearranged and that these rearrangements have devastating consequences on their organ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2010.1200
更新日期：2010-11-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：BACKGROUND:Sorafenib is the standard treatment for advanced hepatocellular carcinoma (HCC). Due to its peculiar toxicities, improving patient's tolerance may need close follow-up. Nurses can play a crucial role, by driving a patient education program (EP). We aimed to prove that adding EP to usual care (UC) improves pa...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/j.bulcan.2016.09.017
更新日期：2016-11-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,随机对照试验
doi：10.1684/bdc.2009.0871
更新日期：2009-05-01 00:00:00
abstract：:We have previously shown that the addition of 4-methylthio-2-oxobutanoate (MTOB) to cultures of methionine dependent neoplastic cells which lack endogenous MTOB restores their capacity to grow in the absence of exogenous methionine. Transition state inhibitors of the MTOB transaminase,responsible for the transaminatio...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1999-10-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：:In terms of pharmacology, drug delivery is an important obstacle in the development of brain tumor chemotherapy. The blood-brain barrier limits the drug penetration in normal brain tissue around the tumor and at distant potential metastatic sites. In the tumor, the altered blood-brain barrier, ie blood-tumor barrier, ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1992-01-01 00:00:00
abstract：:Angiopoietin-2 is a new member of the family of the ligands of Tek (Tie2), a transmembrane receptor with tyrosine kinase activity which is specifically expressed in endothelial cells during angiogenesis. Several lines of evidence indicate that angiopoietin-1 is involved in pericyte recruitment by endothelial cells and...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2003-01-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2009.0844
更新日期：2009-04-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 共识发展会议,杂志文章,实务指引
doi：10.1016/j.bulcan.2017.10.017
更新日期：2017-12-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1994-12-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2002-08-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/j.bulcan.2014.12.001
更新日期：2015-01-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1016/j.bulcan.2017.03.009
更新日期：2017-05-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2014.2040
更新日期：2014-10-01 00:00:00
abstract：NOVEL PERSPECTIVES IN CANCER IMMUNOTHERAPIES:Š. ...
journal_title：Bulletin du cancer
pub_type： 社论
doi：10.1016/S0007-4551(18)30384-9
更新日期：2018-12-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1016/j.bulcan.2018.12.011
更新日期：2019-03-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2012.1677
更新日期：2013-01-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
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journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2002-06-01 00:00:00
