NMR-neuropathologic correlation in stroke.

Abstract:

:True, three-dimensional proton nuclear magnetic resonance imaging at 0.147 tesla was performed postmortem on 2 patients embodying various stroke syndromes, including chronic (4 and 15 years) infarction, subacute (within 1 week) bland infarction, acute (2 days) hemorrhagic infarction, and hematoma secondary to ruptured aneurysm. A third patient, with subcortical arteriosclerotic encephalopathy, so-called Binswanger's disease, was examined antemortem using a 0.6 tesla scanner. Nuclear magnetic resonance images were reconstructed at levels matching the pathologic specimens. Qualitative and, when available, quantitative comparisons between the results of nuclear magnetic resonance imaging and pathology were carried out. Areas of qualitatively prolonged T1 and T2 relaxation times on nuclear magnetic resonance imaging were more extensive than the corresponding areas of chronic infarction noted pathologically and were determined to be infarcts plus the adjacent areas of Wallerian degeneration. Hemorrhagic infarction, without evidence of blood on computed tomography, was found to have mildly prolonged T1 and T2 relaxation times, between those of normal brain and chronic infarction; a 10-day-old hematoma had a very short T1, slightly shorter than that of white matter, and a mildly prolonged T2, with values between those of white and gray matter. Subcortical arteriosclerotic encephalopathy was found to have areas of prolonged T1 and T2 relaxation times involving almost the entire white matter of the corona radiata.

journal_name

Stroke

journal_title

Stroke

authors

DeWitt LD,Kistler JP,Miller DC,Richardson EP Jr,Buonanno FS

doi

10.1161/01.str.18.2.342

subject

Has Abstract

pub_date

1987-03-01 00:00:00

pages

342-51

issue

2

eissn

0039-2499

issn

1524-4628

journal_volume

18

pub_type

杂志文章

相关文献

STROKE文献大全
  • Genomewide linkage in a large Caucasian family maps a new locus for intracranial aneurysms to chromosome 13q.

    abstract:BACKGROUND AND PURPOSE:Familial aggregation of intracranial aneurysms (IAs) indicates a genetic role in the pathogenesis of this disease. Despite a number of reported susceptibility loci, no disease-causing gene variants have been identified. In this study, we used a parametric genomewide linkage approach to search for...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.108.534396

    authors: Santiago-Sim T,Depalma SR,Ju KL,McDonough B,Seidman CE,Seidman JG,Kim DH

    更新日期:2009-03-01 00:00:00

  • Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets.

    abstract:BACKGROUND AND PURPOSE:Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I). We tested the hypothesis that topical pretreatment with the selective potassium channel agonists NS1619 and aprikalim preserves the vasc...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.29.4.837

    authors: Veltkamp R,Domoki F,Bari F,Busija DW

    更新日期:1998-04-01 00:00:00

  • Fibromuscular dysplasia and the brain. I. Observations on angiographic, clinical and genetic characteristics.

    abstract::The angiographic, clinical, and genetic characteristics of fibromuscular dysplasia (FMD) are reviewed in 37 patients (mean age 48 years) selected from a pool of 4000 angiograms of carotid or vertebral arteries. FMD was a neglected pathogenic factor in 28 patients with hemorrhagic or ischemic cerebral lesions. The aneu...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.13.1.46

    authors: Mettinger KL,Ericson K

    更新日期:1982-01-01 00:00:00

  • Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats.

    abstract::We produced unilateral photochemical infarcts in the hindlimb sensorimotor neocortex of 186 rats by intravenous injection of the fluorescein derivative rose bengal and focal illumination of the intact skull surface. Infarcted rats showed specific, long-lasting deficits in tactile and proprioceptive placing reactions o...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.20.10.1383

    authors: De Ryck M,Van Reempts J,Borgers M,Wauquier A,Janssen PA

    更新日期:1989-10-01 00:00:00

  • Transient Ischemic Attack Results in Delayed Brain Atrophy and Cognitive Decline.

    abstract:BACKGROUND AND PURPOSE:Transient ischemic attack (TIA) initiates an ischemic cascade without resulting in frank infarction and, as such, represents a novel model to study the effects of this ischemic cascade and secondary neurodegeneration in humans. METHODS:Patients with suspected TIA underwent acute brain perfusion ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.117.019276

    authors: Bivard A,Lillicrap T,Maréchal B,Garcia-Esperon C,Holliday E,Krishnamurthy V,Levi CR,Parsons M

    更新日期:2018-02-01 00:00:00

  • Intracerebral hemorrhage and head trauma: common effects and common mechanisms of injury.

    abstract::Nontraumatic intracerebral hemorrhage (ICH) remains a devastating condition with 30-day mortality rates of 35% to 52%. Until the pathophysiology of this condition is better understood, it will not be possible to develop effective therapies. Studies of cerebral blood flow and metabolism in patients with acute ICH show ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.595058

    authors: Powers WJ

    更新日期:2010-10-01 00:00:00

  • Telomerase reverse transcriptase upregulation attenuates astrocyte proliferation and promotes neuronal survival in the hypoxic-ischemic rat brain.

    abstract:BACKGROUND AND PURPOSE:Telomerase reverse transcriptase (TERT) is tightly related to the resistance of cells to stress and injury. However, little is known about the roles of TERT in the nervous system. We try to investigate the effects of TERT on the function of astrocytes in developing rat brains subjected to hypoxia...

    journal_title:Stroke

    pub_type: 杂志文章,收录出版

    doi:10.1161/STROKEAHA.111.626325

    authors: Qu Y,Duan Z,Zhao F,Wei D,Zhang J,Tang B,Li J,Yang C,Mu D

    更新日期:2011-12-01 00:00:00

  • Clinical severity in CADASIL related to ultrastructural damage in white matter: in vivo study with diffusion tensor MRI.

    abstract:BACKGROUND AND PURPOSE:CADASIL is a newly recognized cause of subcortical ischemic strokes that progressively leads to dementia associated with pseudobulbar palsy and severe motor disability. This deleterious progression and the severity of clinical presentation are widely variable among affected subjects. The exact ro...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.30.12.2637

    authors: Chabriat H,Pappata S,Poupon C,Clark CA,Vahedi K,Poupon F,Mangin JF,Pachot-Clouard M,Jobert A,Le Bihan D,Bousser MG

    更新日期:1999-12-01 00:00:00

  • Venous sinus thrombosis associated with androgens in a healthy young man.

    abstract:BACKGROUND:Cerebral venous sinus thrombosis is rare and can be promoted by various conditions. We report the case of cerebral venous thrombosis in a patient using androgens. CASE DESCRIPTION:A 31-year-old man using androgens for bodybuilding was admitted for headache and vomiting. He had cerebral venous sinus thrombos...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.1.212

    authors: Jaillard AS,Hommel M,Mallaret M

    更新日期:1994-01-01 00:00:00

  • Autoantibodies against the fibrinolytic receptor, annexin A2, in cerebral venous thrombosis.

    abstract:BACKGROUND AND PURPOSE:Cerebral venous thrombosis (CVT) may be a manifestation of underlying autoimmune disease. Antibodies against annexin A2 (anti-A2Ab) coincide with antiphospholipid syndrome, in which antiphospholipid antibodies (aPLA) are associated with thrombosis in any vascular bed. Annexin A2, a profibrinolyti...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.592121

    authors: Cesarman-Maus G,Cantú-Brito C,Barinagarrementeria F,Villa R,Reyes E,Sanchez-Guerrero J,Hajjar KA,Latorre EG

    更新日期:2011-02-01 00:00:00

  • Safety and feasibility of collateral blood flow augmentation after intravenous thrombolysis.

    abstract:BACKGROUND AND PURPOSE:Collateral flow augmentation using partial aortic occlusion may improve cerebral perfusion in acute stroke. We assessed the safety and feasibility of partial aortic occlusion immediately after intravenous tissue plasminogen activator. METHODS:We conducted an open-label pilot study of partial aor...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1161/STROKEAHA.110.607846

    authors: Emery DJ,Schellinger PD,Selchen D,Douen AG,Chan R,Shuaib A,Butcher KS

    更新日期:2011-04-01 00:00:00

  • Nitric oxide promotes arteriolar dilation during cortical spreading depression in rabbits.

    abstract:BACKGROUND AND PURPOSE:Pial arterioles transiently dilate during cortical spreading depression (CSD), although the mechanisms are unclear. We tested the hypothesis that increased production of nitric oxide (NO) promotes arteriolar dilation. METHODS:Urethane-anesthetized rabbits were equipped with cranial windows, and ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.12.2463

    authors: Colonna DM,Meng W,Deal DD,Busija DW

    更新日期:1994-12-01 00:00:00

  • Linkage of ischemic stroke to the PDE4D region on 5q in a Swedish population.

    abstract:BACKGROUND AND PURPOSE:Recent Icelandic studies have demonstrated linkage for common forms of stroke to chromosome 5q12 and association between phosphodiesterase4D (PDE4D) and ischemic stroke. Using a candidate region approach, we wanted to test the validity of these findings in a different population from northern Swe...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000174188.04716.8d

    authors: Nilsson-Ardnor S,Wiklund PG,Lindgren P,Nilsson AK,Janunger T,Escher SA,Hallbeck B,Stegmayr B,Asplund K,Holmberg D

    更新日期:2005-08-01 00:00:00

  • Nationwide Analysis of Cost Variation for Treatment of Aneurysmal Subarachnoid Hemorrhage.

    abstract::Background and Purpose- Aneurysmal subarachnoid hemorrhage (aSAH) has a high healthcare cost burden. Methods- We performed a cross-sectional analysis of the costs of clipping and coiling of aSAH using the National Inpatient Sample and Vizient databases. We conducted multiple regression analyses to estimate national co...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.023079

    authors: Yoon S,Yoon JC,Winkler E,Liu C,Lawton MT

    更新日期:2018-12-03 00:00:00

  • Relationship between angiographic vasospasm and regional hypoperfusion in aneurysmal subarachnoid hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Angiographic vasospasm frequently complicates subarachnoid hemorrhage and has been implicated in the development of delayed cerebral ischemia. Whether large-vessel narrowing adequately accounts for the critical reductions in regional cerebral blood flow underlying ischemia is unclear. We sought t...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.111.646836

    authors: Dhar R,Scalfani MT,Blackburn S,Zazulia AR,Videen T,Diringer M

    更新日期:2012-07-01 00:00:00

  • Dysphagia in lateral medullary infarction (Wallenberg's syndrome): an acute disconnection syndrome in premotor neurons related to swallowing activity?

    abstract:BACKGROUND AND PURPOSE:We have investigated the pathophysiological mechanisms of dysphagia in Wallenberg's syndrome (WS) that are due to lateral medullary infarction (LMI). METHODS:Twenty patients with WS were evaluated by means of clinical and electrophysiological methods that measured the oropharyngeal phase of volu...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/hs0901.094278

    authors: Aydogdu I,Ertekin C,Tarlaci S,Turman B,Kiylioglu N,Secil Y

    更新日期:2001-09-01 00:00:00

  • Management problems in acute hydrocephalus after subarachnoid hemorrhage.

    abstract::In a consecutive series of 473 patients admitted within 72 hours after a subarachnoid hemorrhage, 91 (19%) had hydrocephalus on the initial computed tomogram. Consciousness was unimpaired in 25 of the 91 (28%). In 11 more patients acute hydrocephalus developed within 1 week after subarachnoid hemorrhage. Thirty-eight ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.20.6.747

    authors: Hasan D,Vermeulen M,Wijdicks EF,Hijdra A,van Gijn J

    更新日期:1989-06-01 00:00:00

  • Occurrence and Predictors of Falls in People With Stroke: Six-Year Prospective Study.

    abstract:BACKGROUND AND PURPOSE:The purpose was to investigate the occurrence of self-reported falls in people with stroke at 3, 6, and 12 months and 6 years post stroke and predictors for falls during 6 years. METHODS:A prospective study involving 121 people with stroke. Data were obtained through structured interviews and as...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.010496

    authors: Minet LR,Peterson E,von Koch L,Ytterberg C

    更新日期:2015-09-01 00:00:00

  • Diffusion- and perfusion-weighted MRI patterns in borderzone infarcts.

    abstract:BACKGROUND AND PURPOSE:The pathophysiology of borderzone infarcts is not well understood. We investigated whether combined diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) could identify pathophysiologically meaningful categories of borderzone infarcts. METHODS:Seventeen patients with borderzone i...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.31.5.1090

    authors: Chaves CJ,Silver B,Schlaug G,Dashe J,Caplan LR,Warach S

    更新日期:2000-05-01 00:00:00

  • Hemorrhage from cavernous malformations of the brain: definition and reporting standards. Angioma Alliance Scientific Advisory Board.

    abstract:BACKGROUND AND PURPOSE:Cavernous malformations of the brain (CMs) cause intracranial hemorrhage, but its reported frequency varies, partly attributable to study design. To improve the validity of future research, we aimed to develop a robust definition of CM hemorrhage. METHODS:We systematically reviewed the published...

    journal_title:Stroke

    pub_type: 共识发展会议,指南,杂志文章,评审

    doi:10.1161/STROKEAHA.108.515544

    authors: Al-Shahi Salman R,Berg MJ,Morrison L,Awad IA,Angioma Alliance Scientific Advisory Board.

    更新日期:2008-12-01 00:00:00

  • Assessing the laryngeal cough reflex and the risk of developing pneumonia after stroke: an interhospital comparison.

    abstract:BACKGROUND AND PURPOSE:We sought to evaluate the efficacy of testing the laryngeal cough reflex in identifying pneumonia risk in acute stroke patients. METHODS:We performed a prospective study of 400 consecutive acute stroke patients examined using the reflex cough test (RCT) compared with 204 consecutive acute stroke...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.30.6.1203

    authors: Addington WR,Stephens RE,Gilliland KA

    更新日期:1999-06-01 00:00:00

  • Prestroke Disability Predicts Adverse Poststroke Outcome: A Registry-Based Prospective Cohort Study of Acute Stroke.

    abstract::Background and Purpose- Information on what effect disability before stroke can have on stroke outcome is lacking. We assessed prestroke disability in relation to poststroke hospital outcome. Methods- Analysis of prospectively collected data from the Sentinel Stroke National Audit Programme. A total of 1656 men (mean ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.027740

    authors: Han TS,Fry CH,Gulli G,Affley B,Robin J,Irvin-Sellers M,Fluck D,Kakar P,Sharma S,Sharma P

    更新日期:2020-02-01 00:00:00

  • Screening for intracranial aneurysm in 355 patients with autosomal-dominant polycystic kidney disease.

    abstract:BACKGROUND AND PURPOSE:the association of autosomal-dominant polycystic kidney disease (ADPKD) with intracranial aneurysm (ICAN) is well known but little is known about the characteristics of ICAN in ADPKD. The purpose of this study was to investigate the prevalence and characteristics of ICAN in ADPKD. METHODS:we scr...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1161/STROKEAHA.110.578740

    authors: Xu HW,Yu SQ,Mei CL,Li MH

    更新日期:2011-01-01 00:00:00

  • Lesion Localization of Poststroke Lateropulsion.

    abstract::Background and Purpose- Hemispheric stroke studies associating lateropulsion (pusher syndrome) with the location of brain lesions have had mixed results from small, unmatched samples. This study was designed to determine whether lateropulsion localizes to specific brain regions across patients with stroke using a case...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.023445

    authors: Babyar SR,Smeragliuolo A,Albazron FM,Putrino D,Reding M,Boes AD

    更新日期:2019-05-01 00:00:00

  • Association of plasma homocysteine concentration with atherosclerotic carotid plaques and lacunar infarction.

    abstract:BACKGROUND AND PURPOSE:Higher plasma total homocysteine (tHcy) levels have been associated with carotid atherosclerosis and cerebral infarction in whites. However, data regarding such associations are limited for Asians. This study examined associations between tHcy levels and severity of carotid atherosclerosis in Jap...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.0000016463.01398.d0

    authors: Sasaki T,Watanabe M,Nagai Y,Hoshi T,Takasawa M,Nukata M,Taguchi A,Kitagawa K,Kinoshita N,Matsumoto M

    更新日期:2002-06-01 00:00:00

  • Stroke and incontinence.

    abstract:BACKGROUND:Urinary incontinence in the acute stage of stroke is seen as a predictor of death, severe disability, and an important factor on hospital discharge destination. Therefore, it is an important measure of stroke severity that not only affects the lives of stroke survivors but also those of caregivers. SUMMARY ...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.str.29.2.524

    authors: Brittain KR,Peet SM,Castleden CM

    更新日期:1998-02-01 00:00:00

  • Neuroimaging markers for early neurologic deterioration in single small subcortical infarction.

    abstract:BACKGROUND AND PURPOSE:Early neurological deterioration (END) occurs in ≥20% of single small subcortical infarctions (SSSIs; axial diameter ≤20 mm in the perforator territories) and deters functional recovery. Both microvasculopathies and atherosclerosis have been proposed to independently contribute to the occurrence ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.114.007466

    authors: Jeong HG,Kim BJ,Yang MH,Han MK,Bae HJ

    更新日期:2015-03-01 00:00:00

  • Cerebral venous blood gas tensions in elevated intracranial pressure.

    abstract::Cerebral venous blood gas tensions were correlated with elevated intracranial pressure in spontaneously breathing dogs lightly anesthetized with nitrous oxide/halothane. Intracranial pressure was elevated by infusion of artificial cerebrospinal fluid into a lateral ventricle. Respiration and blood pressure were monito...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.17.5.946

    authors: Grady PA,Blaumanis OR

    更新日期:1986-09-01 00:00:00

  • Epidemiology and costs of acute hospital care for cerebrovascular disease in diabetic and nondiabetic populations.

    abstract:BACKGROUND AND PURPOSE:Little is known about the pattern of cerebrovascular disease (CVD) for diabetic and nondiabetic patients or about the cost of treatment for CVD in the United Kingdom. The purpose of this study was to extend previous work to describe the epidemiology and cost of acute care of CVD as a frequent com...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.28.6.1142

    authors: Currie CJ,Morgan CL,Gill L,Stott NC,Peters JR

    更新日期:1997-06-01 00:00:00

  • Occipital bone abnormality causing recurrent posterior circulation strokes.

    abstract::We report the case of a young man with recurrent posterior circulation strokes over the course of 6 years. Standard stroke evaluation was unremarkable until careful review of catheter angiogram and CT angiogram images revealed a bony protuberance from the occiput impinging on the left vertebral artery. Local vessel in...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.612176

    authors: Cronin CA,Aldrich EF,Kittner SJ

    更新日期:2011-05-01 00:00:00