Abstract:
:Autonomic functions were studied after withdrawal of all medication in parkinsonian out-patients with short and long duration of disease and in age-matched healthy control subjects. Vagal heart control and noradrenergic response to standing were impaired and related to duration of symptoms of idiopathic parkinsonism. Cholinergic function of pupil motility was unchanged. The cholinergic dysfunction of heart rate variation, therefore, could be due to a specific loss of dopaminergic neurons in the vagal motor nucleus.
journal_name
Neurologyjournal_title
Neurologyauthors
Orskov L,Jakobsen J,Dupont E,de Fine Olivarius B,Christensen NJdoi
10.1212/wnl.37.7.1173subject
Has Abstractpub_date
1987-07-01 00:00:00pages
1173-8issue
7eissn
0028-3878issn
1526-632Xjournal_volume
37pub_type
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