Lecithin/sphingomyelin ratios in tracheal aspirates from newborn infants.

abstract：:We studied healthy and saline lavaged rabbits during high frequency oscillatory ventilation to determine what combination of frequency (f), tidal volume (Vt), and mean airway pressure (Paw) produced the lowest peak-to-peak alveolar pressure amplitude (Palv) and physiologic blood gas tensions. Sinusoidal volume changes...

journal_title：Pediatric research

authors： Kamitsuka MD,Boynton BR,Villanueva D,Vreeland PN,Frantz ID 3rd

更新日期：1990-01-01 00:00:00

abstract：:As the mechanisms controlling the amount and timing of growth saltations are not well understood, the identification of physiologic coupling in weight and length growth are important for further understanding normal growth biology. Thirty-four healthy infants (13 males, 21 females) participated in a longitudinal growt...

journal_title：Pediatric research

authors： Lampl M,Thompson AL,Frongillo EA

更新日期：2005-12-01 00:00:00

abstract：:The purpose of this study was to begin to examine the influence of inhaled NO on O2 toxicity. The survival of Sprague-Dawley rats exposed to >95% O2, >95% O2 + 10 ppm NO, >95% O2 + 100 ppm NO, and >95% O2 + 3 ppm NO2 was determined. Survival at 120 h was 2/24 in >95% O2, 2/12 in >95% O2 + 10 ppm NO, and 1/12 in >95% O...

journal_title：Pediatric research

authors： Nelin LD,Welty SE,Morrisey JF,Gotuaco C,Dawson CA

更新日期：1998-06-01 00:00:00

abstract：:Pulmonary hypoplasia has been associated with absent or hypoplastic pulmonary artery in four cases in humans. Despite these reports, the effects of decreased pulmonary arterial flow on fetal lung growth have not been adequately studied. This study defines the effects of left pulmonary artery (LPA) ligation on fetal lu...

journal_title：Pediatric research

authors： Wallen LD,Perry SF,Alston JT,Maloney JE

更新日期：1990-02-01 00:00:00

abstract：:The present study examined the extent to which abundance of the prolactin receptor (PRLR) and a range of primary mitochondrial proteins are influenced by either maternal nutrition and/or fetal number in adipose tissue. Pregnant sheep were control fed [consuming 100% of total metabolizable energy (ME) requirements (tak...

journal_title：Pediatric research

authors： Budge H,Dandrea J,Mostyn A,Evens Y,Watkins R,Sullivan C,Ingleton P,Stephenson T,Symonds ME

更新日期：2003-02-01 00:00:00

abstract：:We studied the effects of anemia and ouabain administration on cardiac function, oxygen physiology, and blood catecholamine levels in nine newborn lambs. We measured oxygen consumption continuously, along with traditional hemodynamic variables. Oxygen transport was calculated. Following baseline measurements, lambs we...

journal_title：Pediatric research

authors： Berman W Jr,Lister G Jr,Alverson D,Olsen S

更新日期：1987-05-01 00:00:00

abstract：:Newly identified forms of electron transfer flavoprotein (ETF) deficiency in two patients with glutaric aciduria type II (GA II) were described. GA II has been attributed to a defect of either ETF or ETF dehydrogenase, resulting in multiple acyl-CoA dehydrogenation deficiency. ETF is a mitochondrial flavoprotein consi...

journal_title：Pediatric research

authors： Yamaguchi S,Orii T,Suzuki Y,Maeda K,Oshima M,Hashimoto T

更新日期：1991-01-01 00:00:00

abstract：:The objective of this study was to obtain insight into bone formation and resorption in children with newly diagnosed untreated acute lymphoblastic leukemia (ALL). In 23 consecutive children with ALL, a bone biopsy was taken from the crista iliaca posterior under ketamine anesthesia, together with the diagnostic marro...

journal_title：Pediatric research

authors： Leeuw JA,Koudstaal J,Wiersema-Buist J,Kamps WA,Timens W

更新日期：2003-12-01 00:00:00

abstract：:Thyrotropin releasing hormone (TRH) and its precursor peptide pGlu-His-Pro-Gly (TRH-Gly) were measured in serum and in a variety of tissues of developing rats using specific RIA. TRH and TRH-Gly immunoreactivities were detected in most tissues. TRH concentrations were highest in pancreas, in which mean (+/- SEM) TRH c...

journal_title：Pediatric research

authors： Fuse Y,Polk DH,Lam RW,Fisher DA

更新日期：1991-07-01 00:00:00

abstract：:A child presented with obstructive sleep apnea (OSA) and a near-fatal airway obstruction and respiratory arrest shortly after receiving chloral hydrate (CH). We, therefore, hypothesize that CH might selectively depress upper airway maintaining muscles such as the genioglossus and so predispose to airway obstruction. G...

journal_title：Pediatric research

authors： Hershenson M,Brouillette RT,Olsen E,Hunt CE

更新日期：1984-06-01 00:00:00

abstract：:In Brazil, similar intrauterine growth restriction (IUGR) rates were observed between cities with distinct levels of socioeconomic development, challenging the current knowledge that higher rates of IUGR would necessarily be observed in poorer areas than in wealthier ones. Ribeirão Preto, a city located in the most de...

journal_title：Pediatric research

authors： De Farias Aragão VM,Barbieri MA,Moura Da Silva AA,Bettiol H,Ribeiro VS

更新日期：2005-05-01 00:00:00

abstract：:Neonatal group B streptococcal (GBS) sepsis produces pulmonary arterial hypertension and hypoxemia that are preventable by pretreatment with the selective thromboxane A2 synthase inhibitor, dazmegrel. In the present experiment we administered dazmegrel (8 mg/kg) 2 h after the initiation of a 2 1/2 h infusion of 5 X 10...

journal_title：Pediatric research

authors： Truog WE,Gibson RL,Juul SE,Henderson WR,Redding GJ

更新日期：1988-04-01 00:00:00

abstract：:Data are scarce regarding mineral bioavailability from human milk in older infants who may also be receiving solid foods (beikost). We measured the absorption of Ca, Zn, and Fe in 14 healthy, nonanemic 5-7-mo-old breast-fed infants whose mothers milk was extrinsically labeled with stable isotopes (44Ca, 70Zn, and 58Fe...

journal_title：Pediatric research

authors： Abrams SA,Wen J,Stuff JE

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Current tools to predict the severity of respiratory syncytial virus (RSV) infection might be improved by including immunological parameters. We hypothesized that a combination of inflammatory markers would differentiate between severe and mild disease in RSV-infected children. METHODS:Blood and nasopharyng...

journal_title：Pediatric research

authors： Brand HK,Ferwerda G,Preijers F,de Groot R,Neeleman C,Staal FJ,Warris A,Hermans PW

更新日期：2013-02-01 00:00:00

abstract：:We report a study on the effect of herpes simplex virus 1 (HSV-1) infection on apoptosis of neutrophils from both adults and neonates and present evidence showing that HSV-1 enhances apoptosis in neonatal, but not adult, neutrophils. HSV-1 enhanced the expression of both Fas and Fas ligand on the surface of neonatal n...

journal_title：Pediatric research

authors： Ennaciri J,Menezes J,Proulx F,Toledano BJ

更新日期：2006-01-01 00:00:00

abstract：:The purpose of this study was to investigate the effect of constant light in a neonatal care unit on the development of the sleep-and-wakefulness rhythm in preterm infants. Two groups of infants (57 preterm infants without other complications and 58 healthy term infants) were prospectively studied over infancy by a da...

journal_title：Pediatric research

authors： Shimada M,Segawa M,Higurashi M,Akamatsu H

更新日期：1993-02-01 00:00:00

abstract：:Mesenchymal stem cell (MSC) transplantation represents the next breakthrough in the treatment of currently intractable and devastating neonatal disorders with complex multifactorial etiologies, including bronchopulmonary dysplasia, hypoxic ischemic encephalopathy, and intraventricular hemorrhage. Absent engraftment an...

journal_title：Pediatric research

authors： Park WS,Ahn SY,Sung SI,Ahn JY,Chang YS

更新日期：2018-01-01 00:00:00

abstract：:The objective of the present study is to compare the emergence of a circadian respiratory pattern in subsequent siblings of SIDS and controls infants to see whether the unique time and age of SIDS is correlated with altered circadian manifestations. During the first three months of life, a pattern in respiratory rates...

journal_title：Pediatric research

authors： Hoppenbrouwers T,Jensen DK,Hodgman JE,Harper RM,Sterman MB

更新日期：1980-04-01 00:00:00

abstract：:The in vitro incorporation and transport of plasma nonesterified fatty acids into phospholipids of red cell membranes have been studied in cystic fibrosis and healthy children. Red blood cells were labeled in vitro by an active "acyltransferase"-dependent incorporation of radioactively labeled nonesterified fatty acid...

journal_title：Pediatric research

authors： Rogiers V,Mandelbaum I,Mozes N,Vertongen F,Dab I,Crokaert R,Vis HL

更新日期：1982-09-01 00:00:00

abstract：:A double-label, double-substrate incubation technique has been developed and used to study the conversion of progesterone to testosterone in testes extracts from incompletely virilized males. The procedure involves separation of the microsomes from a testicular homogenate, incubating the microsomes with 1 microM [7-3H...

journal_title：Pediatric research

authors： Chasalow FI,Blethen SL,Marr HB,French FS

更新日期：1984-08-01 00:00:00

abstract：:Epidermal growth factor (EGF), a potent mitogen present in milk, is postulated to play an important physiologic role in the ontogeny of the intestine. An artificial rat milk, free of EGF, was developed and fed to newborn rats in an effort to evaluate the physiologic role of EGF on intestinal glucose transport. Compari...

journal_title：Pediatric research

authors： Greene HL,Moore MC,Said HM,Ghishan FK,Orth DN

更新日期：1987-04-01 00:00:00

abstract：:Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) commonly affects premature neonates. The gravity of the consequences associated with GMH-IVH makes it a major concern in their care. GMH-IVH begins in the germinal matrix tissue and is, most commonly, the result of venous rupture. Arteriole-to-venous pre...

journal_title：Pediatric research

authors： Anstrom JA,Brown WR,Moody DM,Thore CR,Challa VR,Block SM

更新日期：2002-10-01 00:00:00

abstract：:125I-Tyr insulin (125I-Tyr Ins) was injected into the vitelline vein of rat fetuses in utero after 17, 19, or 21 days of gestation. Three min later, the weight and radioactivity of various organs and of the remaining carcass were measured. A radioactivity concentration index (RCI) was calculated by dividing the specif...

journal_title：Pediatric research

authors： Sodoyez-Goffaux FR,Sodoyez JC,De Vos CJ

更新日期：1981-09-01 00:00:00

abstract：:Uteroplacental insufficiency alters the anabolic metabolism of the fetus, resulting in intrauterine growth retardation (IUGR). The metabolic and physiologic factors that cause IUGR have long standing consequences after birth. Postnatal growth and glucose metabolism are altered in the IUGR infant. Skeletal muscle is an...

journal_title：Pediatric research

authors： Lane RH,Chandorkar AK,Flozak AS,Simmons RA

更新日期：1998-05-01 00:00:00

abstract：:Oxygen is critical for multicellular existence. Its reduction to water by the mitochondrial electron transport chain helps supply the metabolic demands of human life. The incompletely reduced, reactive oxygen byproducts of this reaction, however, can be quite toxic. In this review, we explore the mechanisms responsibl...

journal_title：Pediatric research

authors： Maltepe E,Saugstad OD

更新日期：2009-03-01 00:00:00

abstract：:Sodium deficiency is associated with decreased muscle growth and protein synthesis. We investigated the influence of diet-induced sodium deficiency on the rate and extent of compensatory growth of the right lung after left pneumonectomy in young rats of 83 +/- 1 g body weight. Starting 1 wk before surgery, all rats we...

journal_title：Pediatric research

authors： Gallaher KJ,Wolpert E,Wassner S,Rannels DE

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:There is an emerging evidence that pulmonary hypertension is associated with amino acid, carnitine, and thyroid hormone aberrations. We aimed to characterize metabolic profiles measured by the newborn screen (NBS) in infants with persistent pulmonary hypertension of the newborn (PPHN) METHODS: Nested case-co...

journal_title：Pediatric research

authors： Steurer MA,Oltman S,Baer RJ,Feuer S,Liang L,Paynter RA,Rand L,Ryckman KK,Keller RL,Jelliffe-Pawlowski LL

更新日期：2018-08-01 00:00:00

abstract：:The purpose of this study is to determine whether the oxidative injury markers, protein carbonyls and malondialdehyde (MDA), are elevated in tracheal aspirates from very low birth weight (< 1500 g) infants; to determine whether levels correlate with myeloperoxidase as a marker of neutrophil inflammation; and to assess...

journal_title：Pediatric research

authors： Buss IH,Darlow BA,Winterbourn CC

更新日期：2000-05-01 00:00:00

abstract：:Previous studies have demonstrated metabolic dysfunction in the mononuclear cells of some children with abnormal cell-mediated immunity. Interpretation of these observations has been complicated by the extreme heterogeneity of cell types examined. The glycolytic metabolism of relatively enriched T-cells, non-T mononuc...

journal_title：Pediatric research

authors： Storch S,Klein W,Feig SA,Henderson T

更新日期：1980-02-01 00:00:00

abstract：:We examined the effect of inspiratory resistive loaded breathing (IRL) on the electromyographic (EMG) activity of the costal and crural diaphragm in nine anesthetized spontaneously breathing piglets (age 10-23 days, weight 2.8-4.4 kg). Bipolar wire electrodes were inserted into the anterior paratendinous costal diaphr...

journal_title：Pediatric research

authors： Watchko JF,Mayock DE,Standaert TA,Woodrum DE

更新日期：1987-01-01 00:00:00