Induction of apoptosis by herpes simplex virus-1 in neonatal, but not adult, neutrophils.

abstract：:We evaluated bone mineralization by single photon absorptiometry at 2 y in a cohort of preterm infants studied since birth. Infants were fed human milk fortified with Ca [to achieve 80 mg/dL (19.96 mmol/L)] and P [40 mg/dL (12.91 mmol/L)] from wk 2 through 8 after birth. After hospital discharge, infants were divided ...

journal_title：Pediatric research

authors： Schanler RJ,Burns PA,Abrams SA,Garza C

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Therapeutic hypothermia (HT) is the only intervention that improves outcomes in neonatal hypoxic-ischemic encephalopathy (HIE). However, the multifactorial mechanisms by which HT impacts HIE are incompletely understood. The complement system plays a major role in the pathogenesis of ischemia-reperfusion inju...

journal_title：Pediatric research

authors： Shah TA,Nejad JE,Pallera HK,Lattanzio FA,Farhat R,Kumar PS,Hair PS,Bass WT,Krishna NK

更新日期：2017-04-01 00:00:00

abstract：:The effect of alpha-adrenergic blockade by phentolamine on the pulmonary vascular response to dopamine was studied in chronically prepared newborn lambs. Dopamine was administered at doses of 2.7 micrograms . kg-1 . min-1, 27 micrograms . kg-1 . min-1 and 270 micrograms . kg-1 . min-1 with and without alpha-adrenergic...

journal_title：Pediatric research

authors： Williams BJ,Drummond WH

更新日期：1983-06-01 00:00:00

abstract：:Defective arousal mechanisms are viewed as contributory to sleep hypopnea disorders and sudden infant death syndrome. Sighs (i.e. augmented breaths) as well as startles have not traditionally been viewed as arousal-related phenomena in infants. We hypothesized that, if sighs and startles are the initial event in a seq...

journal_title：Pediatric research

authors： Wulbrand H,McNamara F,Thach BT

更新日期：1998-11-01 00:00:00

abstract：:Kinetic data are presented for the decarboxylation of branched chain alpha-ketoacids (BCKA) by intact human fibroblasts. Cultured cells of normal individuals and nine patients with different clinical pictures of maple syrup urine disease (MSUD) are studied with both alpha-ketoisocaproic acid (2-oxo-4-methylpentanoic a...

journal_title：Pediatric research

authors： Wendel U,Wentrup H,Rüdiger HW

更新日期：1975-09-01 00:00:00

abstract：:We compared sex-specific growth attainment of a population-based cohort of 147/166 (89%) extremely low birthweight (ELBW < 1000 g) and 131/145 (90%) sociodemographically comparable normal birthweight (NBW) cohort at young adulthood, and examined the pattern of growth trajectories and correlates of growth at ages 1, 2,...

journal_title：Pediatric research

authors： Saigal S,Stoskopf B,Streiner D,Paneth N,Pinelli J,Boyle M

更新日期：2006-12-01 00:00:00

abstract：:To investigate the functional maturity of the lungs of infants with pulmonary hypoplasia, we measured the expression of surfactant apoprotein-A (SP-A) in the autopsied lungs. Autopsied lungs were taken from 16 infants who died at birth or soon after. A lung-to-body weight ratio of less than 1.2% was defined as pulmona...

journal_title：Pediatric research

authors： Minowa H,Takahashi Y,Kawaguchi C,Sadou T,Konishi N,Nishikubo T,Yoshioka A

更新日期：2000-11-01 00:00:00

abstract：:Cell-mediated immunity is not well characterized in very low birth weight infants, and abnormalities may represent a significant vulnerability to infection. This report describes 165 serial studies in 58 infants between 700 and 1300 g birth weight during the first 8 wk of life. Two ml of blood were drawn at 2-wk inter...

journal_title：Pediatric research

authors： Bussel JB,Cunningham-Rundles S,LaGamma EF,Shellabarger M

更新日期：1988-05-01 00:00:00

abstract：:BackgroundLactoferrin (LTF) could play a beneficial role in insulin resistance and diabetes, but the association of its gene variants with cardio-metabolic disorders in children has not been investigated. This study aimed to examine the relationship between LTF variants, plasma LTF concentrations, and cardio-metabolic...

journal_title：Pediatric research

authors： Marcil V,Mayeur S,Lamarche B,England J,Henderson M,Delvin E,Amre D,Levy E

更新日期：2017-11-01 00:00:00

abstract：:Ventilation of immature airways has been shown to result in pressure-induced deformation and alteration of mechanical properties. These changes in mechanical properties may alter the effect of compressive pressures on pressure-flow relationships. To test this hypothesis, unventilated (Group I, n = 8) and ventilated (g...

journal_title：Pediatric research

authors： Penn RB,Wolfson MR,Shaffer TH

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Newborn pigs offer theoretical advantages for studying newborn hypoxic-ischemic (HI) brain damage because of a development and structure similar to the human brain. However, the correlation between functional features and actual HI brain damage has not been reported. METHODS:Newborn pigs were examined daily...

journal_title：Pediatric research

authors： Barata L,Cabañas A,Lafuente H,Vargas C,Ceprián M,Campa L,Jiménez-Sánchez L,Pazos MR,Alvarez FJ,Martínez-Orgado J

更新日期：2019-03-01 00:00:00

abstract：:Contributions from multidisciplinary investigations have focused attention on the potential of tissue engineering to yield novel therapeutics. Congenital malformations, including cleft palate, craniosynostosis, and craniofacial skeletal hypoplasias represent excellent targets for the implementation of tissue engineeri...

journal_title：Pediatric research

authors： Panetta NJ,Gupta DM,Slater BJ,Kwan MD,Liu KJ,Longaker MT

更新日期：2008-05-01 00:00:00

abstract：:Malignant osteopetrosis is a fatal congenital bone disorder characterized by defective osteoclastic function. Death frequently occurs within the first decade of life. The precise molecular defect(s) that causes osteopetrosis is not known. The possibility that osteoclasts, like macrophages, are controlled by interactio...

journal_title：Pediatric research

authors： Rodriguiz RM,Key LL Jr,Ries WL

更新日期：1993-04-01 00:00:00

abstract：:Several lines of evidence suggest that formula with protein content of 3.0 g/100 kcal does not fully meet the protein needs of very-low-birth weight infants. Our purpose was to compare nitrogen balance, metabolic status and growth in infants fed a standard (3.0 g/100 kcal; RegPro) and high (3.6 g/100 kcal; HiPro) prot...

journal_title：Pediatric research

authors： Cooke R,Embleton N,Rigo J,Carrie A,Haschke F,Ziegler E

更新日期：2006-02-01 00:00:00

abstract：:The interrelationship of 2,3-diphosphoglycerate (2,3-DPG) and P50 levels during the fetal and postnatal life were determined in two mammalian species which do not have a switchover of hemoglobin type at the end of their fetal development. In the guinea pig and rabbit, the 2,3-DPG levels remain low during fetal life an...

journal_title：Pediatric research

authors： Bard H,Shapiro M

更新日期：1979-03-01 00:00:00

abstract：:Childhood obesity is a predisposing factor for adult cardiovascular diseases. Human serum paraoxonase (PON1) may protect against atherosclerosis by hydrolyzing lipid peroxides in oxidized LDL. Alterations and potential correlations of PON1 activities, leptin and adiponectin levels in childhood obesity were studied. We...

journal_title：Pediatric research

authors： Koncsos P,Seres I,Harangi M,Illyés I,Józsa L,Gönczi F,Bajnok L,Paragh G

更新日期：2010-03-01 00:00:00

abstract：:We assessed the patterns of Helicobacter pylori (H. pylori) specific maternal antibodies in maternal serum, cord blood, and milk, which might play a role in prevention of H. pylori infection because transferred to the infant. Between November 2000 and November 2001, mothers were recruited after delivery of their offsp...

journal_title：Pediatric research

authors： Weyermann M,Borowski C,Bode G,Gürbüz B,Adler G,Brenner H,Rothenbacher D

更新日期：2005-11-01 00:00:00

abstract：:Concanavalin A surface receptors were detected on brush border enterocytes from child intestinal biopsies by the concanavalin A-peroxidase method. On electron microscopy, these receptors appeared as electron-dense deposits, located on a band running along the innermost part of the brush border membrane glycocalyx. In ...

journal_title：Pediatric research

authors： Vasmant D,Feldmann G,Fontaine JL

更新日期：1982-06-01 00:00:00

abstract：:Fetal lung cyclic AMP phosphodiesterase, cyclic AMP, phosphatidyl choline, and incorporation of precursors into phosphatidyl choline were measured in rabbits after maternal administration of hydrocortisone phosphate and aminophylline. Both agents inhibited lung phosphodiesterase activity and augmented cyclic AMP conce...

journal_title：Pediatric research

authors： Barrett CT,Sevanian A,Lavin N,Kaplan SA

更新日期：1976-06-01 00:00:00

abstract：:In a patient with extrapyramidal movement disorder and extremely low creatinine concentrations in serum and urine, in vivo proton magnetic resonance spectroscopy disclosed a generalized depletion of creatinine in the brain. Oral substitution of arginine, a substrate for creatine synthesis, resulted in an increase of b...

journal_title：Pediatric research

authors： Stöckler S,Holzbach U,Hanefeld F,Marquardt I,Helms G,Requart M,Hänicke W,Frahm J

更新日期：1994-09-01 00:00:00

abstract：:Respiratory parameters of skeletal muscle were determined in permeabilized muscle fibers by adapting a technique described by Veksler et al. for cardiac fibers (Biochim Biophys Acta, 892:191-196, 1987). This method consists of the permeabilization of muscle fibers by saponin by allowing respiratory substrates and inhi...

journal_title：Pediatric research

authors： Letellier T,Malgat M,Coquet M,Moretto B,Parrot-Roulaud F,Mazat JP

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Caffeine is a nonspecific adenosine receptor antagonist used in premature neonates to treat apnea of prematurity. While its use may reduce the incidence of bronchopulmonary dysplasia (BPD), the precise mechanisms remain unknown. Evidence of increased adenosine levels are noted in chronic lung diseases includ...

journal_title：Pediatric research

authors： Dayanim S,Lopez B,Maisonet TM,Grewal S,Londhe VA

更新日期：2014-03-01 00:00:00

abstract：:Pulmonary hypoplasia has been associated with absent or hypoplastic pulmonary artery in four cases in humans. Despite these reports, the effects of decreased pulmonary arterial flow on fetal lung growth have not been adequately studied. This study defines the effects of left pulmonary artery (LPA) ligation on fetal lu...

journal_title：Pediatric research

authors： Wallen LD,Perry SF,Alston JT,Maloney JE

更新日期：1990-02-01 00:00:00

abstract：:Naloxone, a specific opiate antagonist with no agonist properties, in doses of 0.4 and 4.0 mg/kg was found to markedly reduce the duration of primary apnea in asphyxiated newborn rabbits. There was no effect on the duration of the hyperpneic phase (time to primary apnea) or on survival time (time to last gasp). It is ...

journal_title：Pediatric research

authors： Chernick V,Madansky DL,Lawson EE

更新日期：1980-04-01 00:00:00

abstract：:We studied the effects of a diet that was low in fat, high in carbohydrate (CHO) on milk lipid composition and de novo endogenous fatty acid synthesis by the mammary gland in five lactating women. The women consumed either a low fat (LF) (5% fat, 80% CHO) diet or a high fat (HF) (40% fat, 45% CHO) diet. Fat synthesis ...

journal_title：Pediatric research

authors： Hachey DL,Silber GH,Wong WW,Garza C

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Though prenatal antidepressant exposure has been associated with adverse developmental outcomes, the extent to which the effects are due to prenatal drug exposure or underlying maternal mood disturbances is unclear. METHODS:This was a population-based retrospective cohort study using administrative data fro...

journal_title：Pediatric research

authors： Park M,Hanley GE,Guhn M,Oberlander TF

更新日期：2020-12-09 00:00:00

abstract：:In seven patients with mucopolysaccharidoses (1 Hurler, 1 Hurler-Scheie, 4 Hunter, 1 Sly), cranial (1)H-magnetic resonance spectroscopy was performed to evaluate the accumulation of mucopolysaccharides and biochemical changes in the CNS in vivo before and after bone marrow transplantation (BMT). In two of seven patien...

journal_title：Pediatric research

authors： Takahashi Y,Sukegawa K,Aoki M,Ito A,Suzuki K,Sakaguchi H,Watanabe M,Isogai K,Mizuno S,Hoshi H,Kuwata K,Tomatsu S,Kato S,Ito T,Kondo N,Orii T

更新日期：2001-03-01 00:00:00

abstract：:The effect of resuscitation with varying levels of O2 on pulmonary hemodynamics at birth is not well known. We hypothesized that the decrease in pulmonary vascular resistance (PVR) and subsequent response to pulmonary vasoconstrictors and vasodilators will differ following resuscitation with 21%, 50%, or 100% O2 for 3...

journal_title：Pediatric research

authors： Lakshminrusimha S,Russell JA,Steinhorn RH,Swartz DD,Ryan RM,Gugino SF,Wynn KA,Kumar VH,Mathew B,Kirmani K,Morin FC 3rd

更新日期：2007-09-01 00:00:00

abstract：:A specific, enzyme-linked immunoabsorbent assay was used to determine the concentration of the 35,000 mol wt surfactant apoprotein (SP-A) in samples of amniotic fluid obtained from nondiabetic (n = 358) and diabetic (n = 29) women. The enzyme-linked immunoabsorbent assay was performed with rabbit antibodies directed a...

journal_title：Pediatric research

authors： Snyder JM,Kwun JE,O'Brien JA,Rosenfeld CR,Odom MJ

更新日期：1988-12-01 00:00:00

abstract：:The neonate conserves sodium avidly, and sodium intake is normally limited to that present in maternal milk. To evaluate the role of atrial natriuretic peptide (ANP) in this adaptation, preweaned rat pups were artificially reared and fed a formula with either normal sodium (25 mEq/L) or high sodium (145 mEq/L) for 7-8...

journal_title：Pediatric research

authors： Chevalier RL,Muchant DG,Thornhill BA,Belmonte DC,Pence RA,Baertschi AJ

更新日期：1996-08-01 00:00:00