Naloxone decreases the duration of primary apnea with neonatal asphyxia.

abstract：:Intrauterine perfusion failure can cause cerebral malformations. We investigated the effect of transient maternal hypotension on newborn rat brain by inducing hypovolemic hypotension for 2.5 h during early embryonic day 7 (E7) or late (E15) gestation in pregnant rats. We found an increase in the number of TUNEL-positi...

journal_title：Pediatric research

authors： Apak RA,Anlar B,Atilla P,Cakar N

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Infant adiposity is linked to both high maternal fat mass (FM) and excessive gestational FM gain, whereas the association with maternal adipokines is less clear. The aim was to determine how levels of maternal leptin, the soluble leptin receptor (sOB-R), adiponectin, and FM during pregnancy were linked to in...

journal_title：Pediatric research

authors： Andersson-Hall UK,Pivodic A,de Maré HK,Pernilla Svedin J,Carina Mallard E,Albertsson-Wikland KG,Holmäng AB

更新日期：2020-09-14 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a devastating intestinal disease of premature infants. Maternal milk has been suggested to be partially protective against NEC; however, the mechanisms of this protection are not defined. The aim of this study was to examine the effect(s) of artificial feeding of rat milk (RM)-versus...

journal_title：Pediatric research

authors： Dvorak B,Halpern MD,Holubec H,Dvorakova K,Dominguez JA,Williams CS,Meza YG,Kozakova H,McCuskey RS

更新日期：2003-03-01 00:00:00

abstract：:In order to study the neonatal microcirculation, the capillary hemodynamics in skin was investigated in 43 full-term infants 2-7 days after birth. The nailfold capillaries of the thumb were visualized by means of television microscopy and the capillary blood cell velocity (CBV) was videophotometrically quantified in 1...

journal_title：Pediatric research

authors： Norman M,Herin P,Fagrell B,Zetterström R

更新日期：1988-06-01 00:00:00

abstract：:BackgroundTo investigate the association between electronic cigarette (e-cig) use and smoking cessation among smokers who called the Youth Quitline in Hong Kong.MethodsThis longitudinal study collected data on youth smokers' (N=189) use and perception of e-cigs, conventional cigarette smoking behavior, and sociodemogr...

journal_title：Pediatric research

authors： Wang MP,Li WH,Wu Y,Lam TH,Chan SS

更新日期：2017-07-01 00:00:00

abstract：:Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) commonly affects premature neonates. The gravity of the consequences associated with GMH-IVH makes it a major concern in their care. GMH-IVH begins in the germinal matrix tissue and is, most commonly, the result of venous rupture. Arteriole-to-venous pre...

journal_title：Pediatric research

authors： Anstrom JA,Brown WR,Moody DM,Thore CR,Challa VR,Block SM

更新日期：2002-10-01 00:00:00

abstract：:The fetal and maternal concentration of various plasma proteins alters during pregnancy. Cells in the livers of fetal hamsters accumulate serum amyloid A (SAA) and C-reactive protein (CRP) mRNA, major acute phase reactants, when lipopolysaccharide is administered to the fetal circulation. No fetal SAA or CRP mRNA resp...

journal_title：Pediatric research

authors： Dowton SB,Waggoner DJ,Mandl KD

更新日期：1991-11-01 00:00:00

abstract：:Previous studies have shown that proton magnetic resonance spectroscopy (MRS) is useful in predicting neurologic prognosis in children with traumatic brain injury (TBI). Reductions in N-acetyl derived metabolites and presence of lactate have been predictive of poor outcomes. We examined another spectroscopy metabolite...

journal_title：Pediatric research

authors： Ashwal S,Holshouser B,Tong K,Serna T,Osterdock R,Gross M,Kido D

更新日期：2004-10-01 00:00:00

abstract：:The incidence of allergic diseases has increased, and a relation between allergy and dietary fatty acids has been proposed. Modulation of the maternal immune function during pregnancy may have an impact on future clinical outcomes in the child. The aim of this study was to determine the effects of omega (omega)-3 long...

journal_title：Pediatric research

authors： Warstedt K,Furuhjelm C,Duchén K,Fälth-Magnusson K,Fagerås M

更新日期：2009-08-01 00:00:00

abstract：:The ciliated, mucus-secreting urn cell complex (UCC) is found swimming in the coelomic cavity of the marine invertebrate Sipunculus nudus. This cell complex, which can be maintained in suspension cultures, responds to various stimuli by hypersecreting mucus in the form of a cohesive mucus "tail." This tail can be meas...

journal_title：Pediatric research

authors： Kurlandsky LE,Berninger RW,Talamo RC

更新日期：1980-11-01 00:00:00

abstract：:Tracheal aspirate IL-8 concentration and airway epithelial cell IL-8 expression are each increased in premature infants undergoing mechanical ventilation. We sought to determine the cytokines responsible for IL-8 expression in this context. Tracheal aspirates were collected from 18 mechanically ventilated premature in...

journal_title：Pediatric research

authors： Shimotake TK,Izhar FM,Rumilla K,Li J,Tan A,Page K,Brasier AR,Schreiber MD,Hershenson MB

更新日期：2004-12-01 00:00:00

abstract：:Permeability of the blood brain barrier (BBB) for bilirubin and 125I-albumin was studied in 2-d- and 2-wk-old piglets. 125I-albumin was given by bolus at the beginning of each study. Hyperbilirubinemia was produced by an initial bolus infusion of bilirubin and sustained at a plasma bilirubin:albumin molar ratio of app...

journal_title：Pediatric research

authors： Lee C,Oh W,Stonestreet BS,Cashore WJ

更新日期：1989-05-01 00:00:00

abstract：:Uteroplacental insufficiency alters the anabolic metabolism of the fetus, resulting in intrauterine growth retardation (IUGR). The metabolic and physiologic factors that cause IUGR have long standing consequences after birth. Postnatal growth and glucose metabolism are altered in the IUGR infant. Skeletal muscle is an...

journal_title：Pediatric research

authors： Lane RH,Chandorkar AK,Flozak AS,Simmons RA

更新日期：1998-05-01 00:00:00

abstract：:Prenatal exposure to infection and subsequent inflammatory responses have been implicated in the etiology of schizophrenia and autism. In this review, we summarize current evidence from human and animal studies supporting the hypothesis that the pathogenesis of these two disorders is linked via exposure to inflammatio...

journal_title：Pediatric research

authors： Meyer U,Feldon J,Dammann O

更新日期：2011-05-01 00:00:00

abstract：:Superoxide anion generation during severe asphyxia and reventilation was assessed in newborn pigs. Using closed cranial windows over the parietal cortices, superoxide dismutase (SOD)-inhibitable nitroblue tetrazolium (NBT) reduction was determined during asphyxia/reventilation. Asphyxia was induced by turning off the ...

journal_title：Pediatric research

authors： Pourcyrous M,Leffler CW,Mirro R,Busija DW

更新日期：1990-12-01 00:00:00

abstract：:The effect of intrauterine growth retardation (IUGR) on cerebral and adrenal monoamine metabolism was studied in the fetuses of eight nulliparous rat dams after unilateral uterine artery ligation on d 18 of gestation. On d 22 (term = 23 d), four dams were subjected to normoxia and four to hypoxia (10% O2) for 58 min w...

journal_title：Pediatric research

authors： Thordstein M,Hedner T

更新日期：1992-02-01 00:00:00

abstract：:Myocardial oxygen demand may be increased in chronically hypoxemic lambs because of their increased heart rate. Therefore, we determined whether left ventricular (LV) oxygen supply, oxygen uptake and oxygen demand were proportionally increased in 6-wk-old lambs, after 4 wk of hypoxemia (n = 15), as compared with contr...

journal_title：Pediatric research

authors： Dalinghaus M,Willem J,Gratama C,Koers JH,Gerding AM,Zijlstra WG,Kuipers JR

更新日期：1993-10-01 00:00:00

abstract：:One of two slightly different influenza A/ts-1[E] recombinant candidate live vaccines was given intranasally to each of 23 young children. Twelve of 15 children who had no serum HI antibody but who did have serum ANAB at the time of administration became infected and 1 had mild rhinitis. All eight who lacked both type...

journal_title：Pediatric research

authors： Kim HW,Arrobio JO,Brandt CD,Parrott RH,Murphy BR,Richman DD,Chanock RM

更新日期：1976-04-01 00:00:00

abstract：:Bone disease is an important complication among very low birth weight (VLBW, <1500 g) infants. In adults, osteoporosis is associated with polymorphisms of vitamin D receptor (VDR), estrogen receptor (ER), and collagen Ialpha1 (COLIA1) genes. However, limited information is available regarding the role of these polymor...

journal_title：Pediatric research

authors： Funke S,Morava E,Czakó M,Vida G,Ertl T,Kosztolányi G

更新日期：2006-11-01 00:00:00

abstract：:The objective of this study was to establish longitudinal normative limits for home memory monitors during early infancy. Eighty-eight healthy infants were monitored overnight at 0.25-19 wk of age using the Healthdyne Smart Monitor. Apnea settings were 14 s for recording and 40 s for alarm; the bradycardia setting was...

journal_title：Pediatric research

authors： Hunt CE,Hufford DR,Bourguignon C,Oess MA

更新日期：1996-02-01 00:00:00

abstract：:Spleens from 1-20-wk-old guinea pigs infected in utero with Treponema pallidum and age-matched controls, born to normal and heat-killed (56 degrees C, 2 h.) T. pallidum-injected mothers, were examined for their in vitro lymphoproliferative response to phytohemagglutinin, concanavalin A, and lipopolysaccharide. Additio...

journal_title：Pediatric research

authors： Wicher V,Zhao J,Dilwith R,Burger R,Wicher K

更新日期：1997-12-01 00:00:00

abstract：:The purpose of this investigation was twofold: (1) to identify and characterize the enzymatic ATP hydrolysis system of epithelial cilia, and (2) to develop a quantitative, biochemical test for the ciliotoxic cystic fibrosis (CF) factor based on inhibition of ATP utilization by ciliary preparations. Our rationale for s...

journal_title：Pediatric research

authors： Farrell PM,Fox GN,Spicer SS

更新日期：1976-02-01 00:00:00

abstract：:In preterm infants, low levels of insulin like growth factor 1 (IGF-I) have been associated with impaired growth and retinopathy of prematurity. Our objective was to study safety and pharmacokinetics of i.v. administered rhIGF-I with its binding protein 3 (rhIGFBP-3) to preterm infants. At 3 d chronological age, an i....

journal_title：Pediatric research

authors： Löfqvist C,Niklasson A,Engström E,Friberg LE,Camacho-Hübner C,Ley D,Borg J,Smith LE,Hellström A

更新日期：2009-05-01 00:00:00

abstract：:To study the course of regional metabolite concentrations during early brain development, we measured in vivo metabolites [N-acetyl-aspartate (NAA), choline-containing compounds, and myoinositol (M-Ino)] in the precentral area of the cerebrum by short echo-time single volume proton magnetic resonance spectroscopy and ...

journal_title：Pediatric research

authors： Hüppi PS,Fusch C,Boesch C,Burri R,Bossi E,Amato M,Herschkowitz N

更新日期：1995-02-01 00:00:00

abstract：:We measured the cortisol and corticosterone responses to insulin-induced hypoglycemia in 13 growth hormone (GH)-deficient children and 30 short children without GH deficiency. Although there was no difference between the two groups in degree of hypoglycemia attained, baseline cortisol, baseline corticosterone, or cort...

journal_title：Pediatric research

authors： Chasalow FI,Blethen SL

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:The pathogenesis of BPD includes inflammation and oxidative stress in the immature lung. Corticosteroids improve respiratory status and outcome, but the optimal treatment regimen for benefit with low systemic effects is uncertain. METHODS:In a pilot dose escalation trial, we administered ≤5 daily doses of b...

journal_title：Pediatric research

authors： Ballard PL,Torgerson D,Wadhawan R,Hudak ML,Weitkamp JH,Harris J,Asselin J,Chapin C,Ballard RA,McEvoy CT

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND:The effect of birth location on hypothermia-related outcomes has not been rigorously examined in the literature. In this study, we determined whether birth location had an impact on the benefits of whole-body cooling to 33.5 °C for 72 h in term infants (n = 208) with hypoxic-ischemic encephalopathy (HIE) who...

journal_title：Pediatric research

authors： Natarajan G,Pappas A,Shankaran S,Laptook AR,Walsh M,McDonald SA,Ehrenkranz RA,Tyson JE,Goldberg RN,Bara R,Higgins RD,Das A,Munoz B

更新日期：2012-10-01 00:00:00

abstract：:In artificial tubes as well as in blood vessels with diameters less than 500 microns, blood viscosity decreases with decreasing diameter (Fahraeus-Lindqvist effect). Our study measured viscosity of red blood cells (RBC) from 10 preterm infants, 10 term neonates, and 10 adults by means of a capillary viscometer. RBC we...

journal_title：Pediatric research

authors： Zilow EP,Linderkamp O

更新日期：1989-06-01 00:00:00

abstract：:Keratinocyte growth factor (KGF, or fibroblast growth factor 7) was previously reported to enhance the synthesis of surfactant in alveolar type II cells. We investigated the possible interactions between KGF and a glucocorticoid, dexamethasone (Dex), on surfactant protein (SP) gene expression. In cultured fetal rat ty...

journal_title：Pediatric research

authors： Mouhieddine-Gueddiche OB,Pinteur C,Chailley-Heu B,Barlier-Mur AM,Clement A,Bourbon JR

更新日期：2003-02-01 00:00:00

abstract：:The effect of various lipids, proteins, and other substances on the adsorption rate of dipalmitoyl phosphatidylcholine (DPC) was investigated. Each substance was added to a sonicated suspension of DPC in saline, and the surface pressure of the adsorbed surface film was measured using a platinum plate suspended from an...

journal_title：Pediatric research

authors： Meban C

更新日期：1981-07-01 00:00:00