Abstract:
:In the Djungarian hamster, short photoperiods induce regression of testes and accessory glands. There is evidence that the length of time melatonin levels are elevated is the signal conveying the photoperiodic effects to the neuroendocrine axis. When the temporal course of decompression of the pattern of pineal melatonin content was followed after a change from long to short photoperiods by symmetrical extension of the dark time, extension proceeded first into the morning hours. The present study investigated whether, after transition from long to short photoperiods by either extending the dark period into the morning hours, or starting the dark time at noon, differences in the gonadal reaction and in the rate of extension of the pineal pattern ensue. Three and 7 weeks after transition from long to short photoperiods highly significant differences were found in the rate of involution of testes and accessory glands. Regression was more advanced after extension of the dark period into the morning hours. The length of time that pineal melatonin content was elevated also differed markedly between the two groups. After 3 weeks in short photoperiods, the length of the melatonin peak was more than 9 h when the dark period was extended into the morning, but only about 7 h if it was extended into the afternoon. It is suggested that the different rate of gonadal regression after different ways of transition into the same photoperiod is due to the different rate of decompression of the melatonin pattern.
journal_name
Neuroendocrinologyjournal_title
Neuroendocrinologyauthors
Hoffmann K,Illnerová Hdoi
10.1159/000124562subject
Has Abstractpub_date
1986-01-01 00:00:00pages
317-21issue
3eissn
0028-3835issn
1423-0194journal_volume
43pub_type
杂志文章abstract::In addition to the magnocellular hypothalamic nuclei, arginine vasopressin (AVP)-containing neurons have also been identified in limbic structures, including the hippocampus and amygdala. In the present study, we compared the qualitative properties of the in vitro release of AVP from the dissected hypothalamus with th...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126661
更新日期:1994-03-01 00:00:00
abstract::Measurements of electrical activity and intracellular Ca(2+) levels were performed in perforated-patch clamped GH(3) cells to determine the contribution of large-conductance calcium-activated K(+) (BK) channels to action potential repolarization and size of the associated Ca(2+) oscillations. By examining the dependen...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000069509
更新日期:2003-03-01 00:00:00
abstract::Vasoactive intestinal peptide (VIP), a prolactin (PRL)-releasing factor, has been shown to be synthesized within the anterior pituitary. To test the hypothesis that estrogens increase PRL secretion, at least in part, by stimulating VIP secretion, the concentrations of VIP, peptide histidine isoleucine (PHI) and prepro...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125622
更新日期:1990-11-01 00:00:00
abstract::Tissue-specific stem cells are uncovered in a growing number of organs by their molecular expression profile and their potential for self-renewal, multipotent differentiation and tissue regeneration. Whether the pituitary gland also contains a pool of versatile 'master' cells that drive homeostatic, plastic and regene...
journal_title:Neuroendocrinology
pub_type: 杂志文章,评审
doi:10.1159/000100278
更新日期:2007-01-01 00:00:00
abstract::Acute immobilization stress results in changes in the concentration of both dopamine and noradrenaline in specific forebrain limbic system areas, whereas the adrenaline levels remain unchanged. Changes in dopamine concentrations are more restricted than those in noradrenaline concentrations. Dopamine levels are increa...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123413
更新日期:1982-11-01 00:00:00
abstract::The volume of the sexually dimorphic nucleus in the preoptic area (SDN-POA) of the rat brain is severalfold larger in adult male rats than in adult females. This sex difference in brain structure was previously shown to develop under the influence of androgenic and estrogenic hormones during the perinatal period. We t...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000124484
更新日期:1986-01-01 00:00:00
abstract:INTRODUCTION:Several studies have suggested that diet, especially one enriched in microbiota-fermented fibers or fat, regulates behavior. The underlying mechanisms are currently unknown. We previously reported that certain macronutrients (fermentable fiber and protein) regulate energy homeostasis via the activation of ...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000514289
更新日期:2021-01-11 00:00:00
abstract::Serotonin and dopamine neurons have been shown to exert a stimulatory and inhibitory control, respectively, over pituitary release of beta-endorphin-like immunoreactivity (beta-END-LI). In the present study we sought to determine whether an interaction exists between these two reciprocal mechanisms regulating beta-END...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000124439
更新日期:1986-01-01 00:00:00
abstract::The arcuate nucleus-median eminence complex (AM) undergoes major structural and functional changes during normal puberty or if exposed to a pulse of estradiol in the prepuberal period. Those changes are expressed by increased synaptogenesis and by a drastic alteration in the feedback control of anterior pituitary glan...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000124775
更新日期:1987-06-01 00:00:00
abstract::In vivo and in vitro methods have been used to compare the effects of opioid receptor blockade on the functional activity of the hypothalamo-pituitary-gonadal axis in adult (200 g) and sexually immature (50 g) male rats. In the adult, a single injection of the mu-receptor antagonist, naloxone (500 micrograms/100 g bod...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125777
更新日期:1991-06-01 00:00:00
abstract::Following the procedure of Jeffcoate et al. [1974] we have successfully obtained a specific antiserum to LH-RH in rabbits, and are utilizing our antibody to study the synthesis of LH-RH by rat hypothalamic tissues in vitro. Our antibody, used at a dilution of 1:20,000, binds 37% of added 125I-labelled LH-RH, and cross...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000122517
更新日期:1976-01-01 00:00:00
abstract::After the combined treatment with dexamethasone, morphine and pentobarbitone, the electrical stimulation in the rat tuber cinereum induces a rise in plasma corticosterone (CS) level, probably by direct stimulation of the corticoliberin-producing neural elements and the consecutive ACTH release. We have attempted to lo...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000122803
更新日期:1978-01-01 00:00:00
abstract::A consistent group of gonadotropin-releasing hormone (GnRH) cell bodies occurs in the ventral hypothalamic tract at the infundibular lip (IL), just below the arcuate nucleus (ARC), at the site of the so-called GnRH 'pulse generator'. Immunocytochemical studies were performed to examine contacts between these GnRH neur...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000124914
更新日期:1988-03-01 00:00:00
abstract::Growth hormone-releasing hormone (GHRH) stimulates GH secretion in man and the hormonal response is specific. The attenuation of GH response to bolus GHRH after prior exposure of GHRH of up to 24 h was not demonstrated in normal or GH-deficient subjects after more prolonged exposure. This suggests that the partial los...
journal_title:Neuroendocrinology
pub_type: 杂志文章,评审
doi:10.1159/000125793
更新日期:1991-01-01 00:00:00
abstract::The obese gene (OB) product, leptin, has been shown to exert control on metabolic processes such as food intake and body weight homeostasis, possibly through a neuropeptide Y (NPY) neurotransmission. More recently, leptin has been shown to control several neuroendocrine axes, modulating pituitary hormone secretions in...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000054326
更新日期:1998-05-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000082735
更新日期:2004-01-01 00:00:00
abstract::Previous work has demonstrated that N-methyl-D-aspartate (NMDA) is capable of stimulating luteinizing hormone release in a variety of species. Interestingly, the ability of NMDA to stimulate luteinizing hormone release is significantly compromised in castrated male and female rats as compared to intact animals. The pu...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126607
更新日期:1993-12-01 00:00:00
abstract::Met-enkephalin concentrations in the anterior pituitary gland were shown to decline dramatically within the first 24 h after reserpine treatment, with effects apparent as early as 6 h. This was followed by subsequent repletion and late augmentation of Met-enkephalin levels 3 weeks following reserpine. Treatment with t...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000124905
更新日期:1988-02-01 00:00:00
abstract::Experiments were carried out to increase the endogenous levels of TRH in brain and spinal cord. After 7 days of continuous oral ingestion of TRH analogs (D-pGlu-Leu-ProNH2, pGlu-Leu-Pro, pGlu-Pro-ProNH2, or pGlu-Leu-pyrrolidide), spinal cord and brain levels of TRH were elevated, whereas the content of TRH metabolite,...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125118
更新日期:1989-02-01 00:00:00
abstract::The mammalian pineal gland appears to be a major endocrine component in the regulation of photoperiodic responses. The circadian pattern of secretion of the pineal hormone, melatonin, is regulated by the nervous system. Changes in photoperiod, acting via the nervous system, alter the temporal pattern of melatonin secr...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123579
更新日期:1983-11-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123988
更新日期:1984-09-01 00:00:00
abstract::The acute effects of hypothalamic electrical stimulation on the secretion of FSH and LH have been examined in anestrous and estrous ferrets. Basal levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were higher in the anestrous than in the estrous animals; the anestrous animals showed a more mark...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000122674
更新日期:1977-01-01 00:00:00
abstract::Introduction Dysregulation of the mTORC1-dependent pathways in pancreatic neuroendocrine neoplasms (PanNENs) underlies the introduction of the mTORC1 inhibitor everolimus as treatment of advanced progressive PanNENs. Although everolimus significantly increases progression free survival, most patients acquire secondary...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000509865
更新日期:2020-07-02 00:00:00
abstract::Previous studies have shown that the stimulation of LH release by the opiate receptor blocker, naloxone, can be prevented by catecholamine synthesis inhibitors, suggesting opiate regulation of catecholamine release. The present study tested whether an opiate agonist and antagonist would affect the depletion of hypotha...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123899
更新日期:1984-03-01 00:00:00
abstract::Light deprivation by blinding or exposure to short photoperiod results in depressed prolactin (PRL) cell activity and gonadal regression in the male Syrian hamster after at least 42-56 days of treatment, and both of these events can be prevented if pineal removal accompanies light deprivation. In the present study, we...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125272
更新日期:1989-11-01 00:00:00
abstract::The effect of angiotensin II (AII) on plasma prolactin (PRL) concentrations was evaluated in ovariectomized rhesus monkeys which had been conditioned to chair restraining. Intracerebro-ventricular (i.v.t.) microinjections of AII increased PRL plasma levels in a dose-dependent manner. PRL values peaked at 10 min after ...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123389
更新日期:1982-10-01 00:00:00
abstract::The c-fos protein is rapidly induced in hypothalamic magnocellular nuclei following hemorrhage. We used specific antibodies directed against c-fos and either vasopressin (AVP) or oxytocin (OT) neurophysin to investigate c-fos activation in individual AVP and OT neurons. AVP and OT neurons expressed c-fos in response t...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126384
更新日期:1993-03-01 00:00:00
abstract::The effect of glucocorticoids on corticotropin-releasing factor (CRF) gene expression was studied by combination of in situ hybridization histochemistry and steroid implantation. Dexamethasone micropellets, implanted around the hypothalamic paraventricular nucleus (PVN), caused total inhibition of the hybridizable CRF...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000124846
更新日期:1987-10-01 00:00:00
abstract::We determined the effect of 17 beta-estradiol (E2) on synthesis and release of luteinizing hormone (LH) induced by drugs which activate intracellular signal transduction mechanisms in rat anterior pituitary cells. Cells were pretreated with E2 (6 x 10(-10) M) or diluent for 24 h, then washed and incubated for 4 h with...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125405
更新日期:1990-06-01 00:00:00
abstract::We have attempted to elucidate the effect of glucose concentrations on the release of thyrotropin-releasing hormone (TRH), a brain neuropeptide possessing glucoregulatory function, from rat hypothalamic slices in vitro. Rat hypothalamic slices were preincubated for 60 min at 37 degrees C in Krebs-Ringer bicarbonate (K...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125751
更新日期:1991-04-01 00:00:00