Pre- and postnatal influence of an estrogen antagonist and an androgen antagonist on differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats.

abstract：:Multiple unit activity (MUA) was recorded from the adrenocorticotropic area (n. posterior medialis hypothalami, PMH) of unrestrained resting pigeons throughout the 24 h period and compared with plasma corticosterone levels (B). Bilateral electrolytic lesions of the hippocampus suppressed diurnal variations of MUA and ...

journal_title：Neuroendocrinology

authors： Bouillé C,Baylé JD

更新日期：1978-01-01 00:00:00

abstract：:Somatostatin (ST) inhibits gastrointestinal motility and exocrine and endocrine secretions. In animals, ST has been demonstrated to decrease food intake. We investigated, in a randomized double-blind investigation in 10 healthy humans, the effects of an intravenous ST infusion compared to saline on subjective hunger f...

journal_title：Neuroendocrinology

authors： Lieverse RJ,Jansen JB,Masclee AM,Lamers CB

更新日期：1995-02-01 00:00:00

abstract：:The facilitation of sexual receptivity by oxytocin (OT) in female rats is related to the regulation of oxytocin receptors (OTR) by ovarian steroids in the ventromedial nuclei (VMN) of the hypothalamus. In a previous study, we have shown that estradiol benzoate (EB) causes a twofold increase in OTR binding in the VMN. ...

journal_title：Neuroendocrinology

authors： Coirini H,Johnson AE,Schumacher M,McEwen BS

更新日期：1992-03-01 00:00:00

abstract：:The A1 and A2 brainstem noradrenergic cell groups project to the hypothalamic paraventricular nucleus (PVN), which is involved in integrating the stress response. Bi-directional communication between the brain and immune system is well established, with both neuroendocrine and immune responses being activated by lipop...

journal_title：Neuroendocrinology

authors： Condé GL,Renshaw D,Zubelewicz B,Lightman SL,Harbuz MS

更新日期：1999-09-01 00:00:00

abstract：:In 2016, the third version of guidelines for the diagnosis and treatment of neuroendocrine tumors (NETs) has been published by the European Neuroendocrine Tumor Society (ENETS). These guidelines reflect the progress in treatment of NETs, and by comparing the newest guidelines with the first guidelines of 2001, this pr...

journal_title：Neuroendocrinology

authors： Zandee WT,de Herder WW

更新日期：2018-01-01 00:00:00

abstract：:To study the eyes' role in maintaining the circadian rhythm in pituitary-adrenal function, 24-h patterns of corticosterone levels were compared in intact and blinded adult female rats. Rats were blinded by optic enucleation at approximately 80 days of age. Nonstress plasma corticosterone levels were determined fluorom...

journal_title：Neuroendocrinology

authors： Wilson MM,Rice RW,Critchlow V

更新日期：1976-01-01 00:00:00

abstract：:Molecules of astrocyte origin influence gonadotropin-releasing hormone (GnRH) release and GnRH neuronal growth and differentiation. Furthermore, type 1 astrocytes express steroid receptors, presenting the possibility that steroid actions on GnRH neurons might occur via astrocytes. Utilizing GT1-7 cells, a GnRH-secreti...

journal_title：Neuroendocrinology

authors： Zwain IH,Arroyo A,Amato P,Yen SS

更新日期：2002-06-01 00:00:00

abstract：:The present study was aimed at evaluating chronic stress models in mice with special attention to morphine treatment. We hypothesized that repeated periods of drug withdrawal induce chronic stress. To verify this hypothesis, mice were made dependent on morphine and then subjected to several types of repeated withdrawa...

journal_title：Neuroendocrinology

authors： Zelena D,Barna I,Mlynarik M,Gupta OP,Jezova D,Makara GB

更新日期：2005-01-01 00:00:00

abstract：:The in vitro release of LHRH from hypothalami of adult male rats (intact, 5-day castrates, 5-day castrates replaced with various doses of testosterone) was measured under basal conditions and after the addition of KCl, the opiate antagonist naloxone or the opiate agonist DAGO to the perifusion medium. Hypothalami from...

journal_title：Neuroendocrinology

authors： Nikolarakis KE,Pfeiffer DG,Almeida OF,Herz A

更新日期：1986-01-01 00:00:00

abstract：:It is not known where melatonin acts to influence the neuroendocrine axis of seasonally breeding mammals. However, since the pars tuberalis (PT) contains the highest density of melatonin receptors, this adenohypophyseal subdivision is a potential target. Gonadotropes are the only immunocytochemically detectable adenoh...

journal_title：Neuroendocrinology

authors： Skinner DC,Robinson JE

更新日期：1997-10-01 00:00:00

abstract：:The hypothalamic peptide kisspeptin (metastin), the endogenous ligand of the G protein-coupled receptor KISS1R, plays a critical role in controlling GnRH release from hypothalamic GnRH neurons and thereby regulates hypothalamic-pituitary-gonadal functions. Although the therapeutic potential of kisspeptin is attractive...

journal_title：Neuroendocrinology

authors： Matsui H,Asami T

更新日期：2014-01-01 00:00:00

abstract：:The effect of angiotensin II (AII) on plasma prolactin (PRL) concentrations was evaluated in ovariectomized rhesus monkeys which had been conditioned to chair restraining. Intracerebro-ventricular (i.v.t.) microinjections of AII increased PRL plasma levels in a dose-dependent manner. PRL values peaked at 10 min after ...

journal_title：Neuroendocrinology

authors： Dufy-Barbe L,Rodriguez F,Arsaut J,Verrier D,Vincent JD

更新日期：1982-10-01 00:00:00

abstract：:The mechanisms by which leptin influences energy homeostasis are not entirely understood. Several observations indicate that proopiomelanocortin (POMC) is involved in the regulation of food intake and may be a mediator of leptin action. To further study this interaction, a sensitive solution hybridization assay was us...

journal_title：Neuroendocrinology

authors： Korner J,Chua SC Jr,Williams JA,Leibel RL,Wardlaw SL

更新日期：1999-12-01 00:00:00

abstract：:The present study was designed to investigate the role of glucocorticoids in mediating the stimulatory effect of interleukin-1 (IL-1) upon the adrenocortical (AC) axis. Intact male rats were injected with either vehicle or dexamethasone (DEX) (5-50 micrograms/100 g b.w.) and were subsequently exposed to ether stress o...

journal_title：Neuroendocrinology

authors： Weidenfeld J,Abramsky O,Ovadia H

更新日期：1989-12-01 00:00:00

abstract：:Chronic exposure to Delta(9)-tetrahydrocannabinol (Delta(9)-THC) increases corticotropin-releasing hormone (CRH) and proopiomelanocortin (POMC) gene expression in the rat hypothalamus. The levels of circulating gonadal steroids concurrently modulate both neuropeptides in male and female rats. However, it remains unkno...

journal_title：Neuroendocrinology

authors： Corchero J,Manzanares J,Fuentes JA

更新日期：2001-09-01 00:00:00

abstract：:An abolishment of 24 h periodicity of the adrenocortical activity was observed in rats subjected to a prolonged food deprivation of 7--8 days. Total locomotor activity progressively decreased and its circadian rhythm faded out in a similar fashion as the adrenocortical rhythm. The circadian rhythms of both locomotor a...

journal_title：Neuroendocrinology

authors： Kobayashi K,Takahashi K

更新日期：1979-01-01 00:00:00

abstract：:Incubation of cultured goldfish pituitary cells with 10 nM to 1 microM apomorphine (APO), a non-selective dopamine agonist, increased growth hormone (GH) release in a dose-dependent manner. GH release was also stimulated in a dose-dependent manner by 0.1 nM to 1 microM salmon gonadotropin (GTH)-releasing hormone (sGnR...

journal_title：Neuroendocrinology

authors： Chang JP,Yu KL,Wong AO,Peter RE

更新日期：1990-06-01 00:00:00

abstract：:We have investigated the effects of hyperprolactinemia, produced by pituitary isografts under the kidney capsule (16-20 days), on the LH releasing action and priming effect of LH-releasing hormone (LHRH) in normal and hypogonadal (hpg) female mice. The pituitary grafts increased the plasma prolactin concentrations abo...

journal_title：Neuroendocrinology

authors： Lewis CE,Fink G,Dow RC,Morris JF

更新日期：1986-01-01 00:00:00

abstract：:The recent description of infertility in humans with loss-of-function mutations in genes for neurokinin B (NKB) or its receptor (NK3R) has focused attention on the importance of this tachykinin in the control of GnRH secretion. In a number of species, NKB neurons in the arcuate nucleus also produce two other neuropept...

journal_title：Neuroendocrinology

authors： Goodman RL,Coolen LM,Lehman MN

更新日期：2014-01-01 00:00:00

abstract：:Increases in the level of cAMP stimulate the secretion of GnRH from GT1 GnRH neuronal cells. We hypothesized that cyclic nucleotide phosphodiesterases (PDEs), the enzymes that hydrolyze cAMP, may constitute a negative feedback signaling mechanism for GnRH regulation by decreasing the level of cAMP. GT1 cells were show...

journal_title：Neuroendocrinology

authors： Sakakibara H,Conti M,Weiner RI

更新日期：1998-12-01 00:00:00

abstract：:The level of thyroid hormone in blood has been acutely decreased by about 20--30% within 20 min with the aid of isovolemic exchange transfusion (IET) of thyroid hormone free blood cell suspension (THFBCS) in three groups of rats: (1) intact control (C); (2) median eminence (ME)-lesioned; (3) thalamus (TH)-lesioned. Th...

journal_title：Neuroendocrinology

authors： Langer P,Földes O,Mess B,Kokesová H,Gschwendtová K

更新日期：1977-01-01 00:00:00

abstract：:Adenylate cyclase activity was studied in anterior pituitary homogenates from young adult (6 months) and old (20 and 24 months) male rats. Basal, NaF-, GTP-, 5'-guanylimidodiphosphate (Gpp(NH)p)- and forskolin-stimulated activities were similar in the three groups, implying that the stimulatory guanyl nucleotide regul...

journal_title：Neuroendocrinology

authors： Robberecht P,Gillard M,Waelbroeck M,Camus JC,De Neef P,Christophe J

更新日期：1986-01-01 00:00:00

abstract：:The role of endogenous opiate peptides in the mesencephalic central gray (MCG) and their possible interactions with gonadotropin-releasing hormone (GnRH) in the regulation of lordosis behavior was assessed in ovariectomized, estrogen-treated and estrogen-progesterone-treated female rats. Lordosis behavior triggered by...

journal_title：Neuroendocrinology

authors： Sirinathsinghji DJ

更新日期：1984-09-01 00:00:00

abstract：:Concentrations of luteinizing hormone (LH) and prolactin (Prl) in the serum of anestrous and cycling ewes were compared. The concentration of LH in serum and the frequency of episodic releases of LH were lower in anestrous than in cycling ewes. Concentrations of LH in serum rose as rapidly after ovariectomy of anestro...

journal_title：Neuroendocrinology

authors： Jackson GL,Davis SL

更新日期：1979-01-01 00:00:00

abstract：:An electrophysiological investigation was conducted on the connection of medial preoptic neurons with the median eminence and the basal and corticomedial amygdala in pentobarbital anesthesized male Sprague-Dawley rats. Of 411 medial preoptic neurons tested with median eminence stimuli, antidromic responses (mean laten...

journal_title：Neuroendocrinology

authors： Layton BS,Lafontaine S,Renaud LP

更新日期：1981-01-01 00:00:00

abstract：:Parturition is initiated in sheep by an increase in the activity of the fetal hypothalamus-pituitary-adrenal (HPA) axis. Prostaglandins, known to augment the activity of this endocrine axis, have long been proposed as involved in the initiation of paturition. We have previously demonstrated that endogenously produced ...

journal_title：Neuroendocrinology

authors： Deauseault D,Giroux D,Wood CE

更新日期：2000-05-01 00:00:00

abstract：:Recent studies have shown that primary hypothyroidism induced in the rat was able to stimulate the biosynthesis of vasoactive intestinal peptide (VIP) in the anterior pituitary (AP). Since the AP VIP is known to stimulate prolactin (PRL) secretion through a paracrine and/or autocrine mechanism, it is interesting to hy...

journal_title：Neuroendocrinology

authors： Watanobe H,Sasaki S

更新日期：1995-02-01 00:00:00

abstract：:The effects of ovarian steroids on baseline blood pressure and on changes of mean arterial pressure in response to centrally administered angiotensin II, prostaglandin E1, and prostaglandin E2 were examined. Ovariectomized rats treated with estradiol or progesterone showed no change of resting blood pressures relative...

journal_title：Neuroendocrinology

authors： Skoog KM,Kenney NJ

更新日期：1983-02-01 00:00:00

abstract：:The purpose of these studies was to determine the temporal requirements and time of day required for progesterone (P4) to amplify versus extinguish LH surges. The experimental animal model used in these studies was the 7-day ovariectomized rat (day 0) treated continuously with estradiol (E2) for 2-4 days (days 2, 3 or...

journal_title：Neuroendocrinology

authors： Barraclough CA,Camp P,Weiland N,Akabori A

更新日期：1986-01-01 00:00:00

abstract：:In situ hybridization was used to examine the effects of amygdala kindling on the expression of mRNAs for mineralocorticoid receptors (MR) and glucocorticoid receptors (GR) in the rat hippocampus. Kindling increased MR mRNA levels in the dentate gyrus of the hippocampus 4 h after the last seizure, and these levels rem...

journal_title：Neuroendocrinology

authors： Clark M,Smith MA,Weiss SR,Post RM

更新日期：1994-05-01 00:00:00