Abstract:
:The influence of bilateral injections of serotonin (5-HT) and methysergide (MET) to antero-medial hypothalamus (HA) on carbachol-induced emotional-defensive behavior was investigated. Earlier (15 min) stimulation of 5-HT receptors in HA region by 5-HT injections evoked a decrease in the level of vocal response (number and time of growling), while previous blocking of these receptors by means of MET brought about a considerable increase of vocalization level evoked by carbachol (Cch) injections (10 pg) to the same loci of HA. Intrahypothalamic injections of 5-HT alone or MET did not evoke any observable changes in the animals behavior. The alterations of the level of Cch-induced vocal response 3 to 35 days after chemical damage of 5-HT neurons in HA or in the middle forebrain bundle (MFB) in posterolateral hypothalamus caused by 5,7-dihydroxytryptamine were examined. Local neurotoxin injections both to MFB and to HA evoked a long lasting increase in the level of Cch-induced vocalization, which began on the 5th-7th day after lesioning and lasted till the completion of the experiment (35 days). Results data indicate that the 5-HT system exerts an inhibiting influence on the emotional-defensive behavior induced by the cholinergic system.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Gołebiewski H,Romaniuk Asubject
Has Abstractpub_date
1985-01-01 00:00:00pages
25-36issue
1-2eissn
0065-1400issn
1689-0035journal_volume
45pub_type
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
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更新日期:1992-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
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更新日期:1996-01-01 00:00:00
abstract::It is well known that the fetal ethanol exposure and prenatal stress may have adverse effects on brain development. Interestingly, some morphological and functional recovery from their teratogenic effects that take place during brain maturation. However, mechanisms that underlie this recovery are not fully elucidated....
journal_title:Acta neurobiologiae experimentalis
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doi:
更新日期:2019-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
abstract::The interaction between kinins formed in central nervous system and acetylcholine was studied. Endogenous ACh in excess acted psychodepressively on the animal's behavior as evaluated with Lat's test. This effect was more intense in those rats in which the activity of kinin-forming enzymes in the nervous tissue had bee...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::A mixture of fibrinopeptides A and B did not evoke any significant central effects when given by intraperitoneal injection, whereas it increased psychomotor activity when injected into a cerebral ventricle. The fibrinopeptides when given by intraperitoneal injection interacted with amphetamine to increase locomotor ac...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::During the first two postnatal weeks postural reflexes were either absent or abortive. First adult-like patterns of reactions were seen at the end of the 3rd week but they could be regularly elicited only by the 6th-9th week. ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2020-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:10.21307/ane-2017-017
更新日期:2016-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
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doi:
更新日期:2005-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
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doi:
更新日期:2006-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
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journal_title:Acta neurobiologiae experimentalis
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doi:
更新日期:2010-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
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