Abstract：
:Rats with electrolytic lesions of the nucleus basalis magnocellularis were compared to sham-lesioned rats in the retention of a continuously reinforced lever-pressing response and in the acquisition and reversal of a visual discrimination task. The muscarinic agonist pilocarpine, in conjunction with the peripheral muscarinic antagonist methyl-scopolamine, was administered in three doses to subsets of each group during acquisition. The lesion interfered with retention of the lever-pressing response. It did not affect the rate of acquisition of the visual discrimination, but facilitated reversal, and increased the number of perseverative errors made by the rats. Pilocarpine's only notable effect was to increase the latency to respond.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Wilson WJ,Cook JAsubject
Has Abstractpub_date
1995-01-01 00:00:00pages
295-9issue
4eissn
0065-1400issn
1689-0035journal_volume
55pub_type
杂志文章abstract：:Techniques (push-pull cannula, cup, brain ventricles perfusion) allowing estimation of the amount of the ACh released in vivo from the brain are described. The main attention is paid to biochemical, physiological and morphological factors influencing the amount of ACh released and available for estimation. Conditions ...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:The effect of central, short-term melatonin administration on daily GnRH and LH secretion was studied in ewes during seasonal anestrus. Melatonin, in a total dose of 32 micrograms and the vehicle were perfused for 4 hours into the mediobasal hypothalamus/median eminence (MBH/ME). The mean GnRH concentration during per...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The effect of anorectic dose of amphetamine on some correlates of arousal (hippocampal EEG and EOG activity) was examined in cats. After injection of amphetamine the frequency of hippocampal rhythmic slow activity and EOG activity increased when preinjection value of rhytmic slow activity was low, but decreased when i...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:The purpose of this study was to determine if the contribution of a muscle to an increase in VT remained the same regardless of the chemical stimulus used to provoke the increase. In seven anaesthetized cats one phrenic nerve was transected and placed on platinum electrodes. The activity was rectified and integrated. ...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1973-01-01 00:00:00
abstract：:The parabrachial complex has been related to various rewarding or aversive behavioral processes, including taste aversion learning and conditioned place aversion. This study examined the effect of tiapride, an antagonist of D2/D3 dopaminergic receptors, on place aversion induced by electrical stimulation of the extern...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：:The cortex of the middle suprasylvian sulcus was removed unilaterally in cats with brain stem transected at the pretrigeminal level. The vertical following reflex was evoked by a slit of light (1 degree x 4 degrees) moving along the vertical meridian or parallel to it up to 40 degrees in the left or right hemifield. T...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Our work assesses the effects of mu opioid receptor activation on high-threshold Ca2+/Ba2+ currents in freshly dispersed pyramidal neurons of the medial prefrontal cortex in rats. Application of the specific mu receptor agonist (D-Ala2+, N-Me-Phe4+, Gly5+-ol)-enkephalin (DAMGO) at 1 microM decreased Ca2+ current ampli...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:The aim of the study was to evaluate REM sleep parameters, especially the temporal characteristics of rapid eye movement activity, in depressed patients, and to compare three different methods for scoring of REM density. The sleep of 15 nonmedicated depressed patients and 13 healthy controls was recorded during two co...
journal_title：Acta neurobiologiae experimentalis
pub_type： 临床试验,杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:Abnormal auditory temporal processing might be an underlying deficit in language disabilities. The auditory temporal-order threshold, one measure for temporal processing abilities, is defined as the shortest time interval between two acoustic events necessary for a person to be able to identify the correct temporal or...
journal_title：Acta neurobiologiae experimentalis
pub_type： 临床试验,杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Partial deafferentation of the hippocampus due to trimethyltin (TMT) intoxication has been reported to induce plastic rearrangements of neuronal elements but the factors that direct these responses are unknown. To assess the possible involvement of nerve growth factor (NGF) in the phenomenon we evaluated the presumabl...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Cyto- and myeloarchitectonics as well as acetylcholinesterase activity of the nucleus limitans thalami--an important part of the nociceptive system--were studied in insectivora (Sorex araneus, Erinaceus europaeus, Talpa europaeus), rat, rabbit, cat, monkey and man. Our results suggest that nucleus limitans is phylogen...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:During the normal course of neuronal differentiation gangliosides undergo marked changes in both quantity and quality. These changes, i.e. several-fold increase in concentration and appearance of the gangliotetraose family, have been observed both in vivo and in neuronal cell cultures. In addition to these naturally o...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：:The acute cerveau isole rat shows spindle bursts of large amplitude alternating with low voltage activity in the frontal cortex and continuous theta rhythm in the dorsal hippocampus. These patterns closely resemble an "intermediate" stage of sleep-waking cycle, when the forebrain structures seem to be functionally dis...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Cholinesterase inhibitors are currently the mainstream of symptomatic treatment of patients with Alzheimer's disease. The response to treatment with cholinesterase inhibitors is clinically difficult to predict. Several demographic, clinical and biological variables have been proposed as pretreatment predictors of long...
journal_title：Acta neurobiologiae experimentalis
pub_type： 临床试验,杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:In normal dogs a differentiation task consisting of lifting the left or right foreleg in response to the tactile stimuli administered to the left or right side of the body respectively is very difficult, requiring from 500 to 1,000 trials. On the contrary the same task presented to other dogs after transection of the ...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1973-01-01 00:00:00
abstract：:The variability of simple actions with response to auditory stimuli was studied under different delay conditions. Subjects reacted as fast as possible or with a defined time delay (from 250 to 750 ms) to a tone switching off by pressing a response-key with the left index finger (controlled by the right hemisphere) or ...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:A review of recent anatomical evidence shows that every neocortical area and many nuclei from the dorsal thalamus project to restricted neostriatal regions. The neurobehavioral literature offers many examples of the same results obtained with lesions, stimulations or recordings in a neocortical area and the associated...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：:Stroke is the second leading cause of death worldwide, affecting about 240 people a day in South Africa and leaving survivors with residual disabilities. At the moment, there is no clinically approved neuroprotective product for stroke but the consumption of plant polyphenols has been suggested to offer some protectio...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：10.21307/ane-2017-040
更新日期：2017-01-01 00:00:00
abstract：:The changes of intertrial response (ITR) rate along the intertrial interval duration were examined in 30 rats trained in two-way avoidance. The lowest ITR rate was observed just after a cross-through response terminating a trial. Rats trained with a warning signal of darkness showed over-all higher ITR rates and short...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The midbrain was isolated from the pons and forebrain by two brainstem transections, pretrigeminal and "preoptic", inclined at 32 degree or 35 degree to the vertical plane. The preoptic transection passed along the rostral border of the optic tract, leaving it and the chiasm intact. Thus, direct visual input into the ...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:The finding of stem/progenitor cells in postnatal bone marrow and umbilical cord blood, opens up a possibility of using stem cells to treat neurologic diseases. There is a controversy, whether intravenously administered human umbilical cord blood cells (HUCBC) migrate to the brain, differentiate and improve recovery a...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Inherited or acquired oligodendrocyte deficiency or abnormalities usually lead to severe neurological disorders, common in humans and animals. The wide spectrum of diseases to be treated, their frequency and lack of effective treatments result in an urgent need to elaborate alternative options such as cell replacement...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：:Thyroid hormones are essential for normal brain development and very important in the normal functioning of the brain. Thyroid hormones action in the adult brain has not been widely studied. The effects of adult hyperthyroidism are not as well understood as adult hypothyroidism, mainly in hippocampal granular cells. T...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:The intergeniculate leaflet (IGL) of the thalamus constitutes a small but important part of the neural network controlling circadian activity in rodents. It appears that IGL integrates photic cues from retina with non-photic information originating from different nonspecific brain systems. Subsequently, this integrate...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：:In awake rabbits, which received auditory stimuli paired with electric shock to a forelimb, the activity of 229 units were recorded. In 118 units conditioned responses were observed. In 68 units they were excitatory and in 50 units, inhibitory in accordance with the excitatory or inhibitory effect of the reinforcing s...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1973-01-01 00:00:00
abstract：:In an effort to determine the plasticity of the proliferative matrix of the hippocampus in an adult rat to environmental manipulation, the following study was conducted. Fifteen adult male Long-Evans rats (6 months old at the start of the experiment) were placed into two different environments for 3 months. Seven anim...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Adult, male, Long-Evans hooded rats were subjected to a spinal cord transection in the mid-thoracic region. Following surgery, animals were divided into groups for treatments with ACTH, Piromen, isobutyl-2-cyanoacrylate and Cytoxan. Animals were sacrificed at varying intervals from 7-180 days. Horizontal sections of t...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:In the context of cell therapy, the epigenetic status of core stemness transcription factor (STF) genes regulating the cell proliferation/differentiation program is of primary interest. Our results confirmed that in vitro differentiation of the umbilicalcord-blood-derived-neural-stem-cells (HUCB-NSC) coincides with th...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Multiple neuronal activity, recorded through chronically implanted electrodes, was analyzed. During acquisition and consolidation of alimentary conditioned reflexes to electrostimulation of the lateral geniculate body or optical tract, the patterns of neuronal activity in the visual cortex and sensory motor cortex bec...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:Neuron transplantation is considered to be a promising therapeutic method to replace functions lost due to central nervous system (CNS) damage. However, little is known about the extent to which implanted neuron-like cells can develop into mature neurons and acquire essential properties, and especially formation of sy...
journal_title：Acta neurobiologiae experimentalis
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
