Abstract:
:The effect of central, short-term melatonin administration on daily GnRH and LH secretion was studied in ewes during seasonal anestrus. Melatonin, in a total dose of 32 micrograms and the vehicle were perfused for 4 hours into the mediobasal hypothalamus/median eminence (MBH/ME). The mean GnRH concentration during perfusion with melatonin decreased significantly (P < 0.05), as compared to the concentration during the preceding perfusion with the vehicle only. This change resulted from high variations in GnRH concentration noted during the initial phase of perfusion rather than from an action of melatonin. Melatonin perfused into the MBH/ME did not significantly affect LH secretion. A higher dose of melatonin and vehicle were also infused intracerebroventricularly (icv.) in either intact (300 micrograms for 3 hours) or ovariectomized (OVX) ewes (400 micrograms for 4 hours, 100 micrograms/100 microliters/h). In the intact animals, melatonin did not significantly affect LH secretion. Interestingly, melatonin significantly decreased (P < 0.05) the number of LH peaks in OVX ewes. These results demonstrate that melatonin delivered for a few hours directly into the central nervous system did not affect either daily hypothalamic GnRH release or pituitary LH secretion in intact ewes during seasonal anestrus, but did modify pulsatile LH secretion in ewes deprived of the negative feedback of estradiol.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Romanowicz K,Misztal T,Gajewska A,Barcikowski Bsubject
Has Abstractpub_date
2001-01-01 00:00:00pages
289-97issue
4eissn
0065-1400issn
1689-0035journal_volume
61pub_type
杂志文章abstract::Proprioceptive effects (PE) on directional hearing, i.e., sound image shifts relatively to the sound source, produced by changes in head position, were studied in their dependence on head movement type in two groups of listeners. The first group included subjects in whom horizontal head deviation to the right or to th...
journal_title:Acta neurobiologiae experimentalis
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
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journal_title:Acta neurobiologiae experimentalis
pub_type: 临床试验,杂志文章
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更新日期:1996-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
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doi:
更新日期:2010-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
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更新日期:1980-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
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更新日期:2000-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
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doi:
更新日期:2013-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract::A immunohistochemical study of postnatal development of the paraclaustral reservoir of migrating cells in the rat brain was performed using anti-GFAP (for astroglia), ED1 and OX-42 (for microglia) antibodies. From birth to the 4th day of postnatal life most GFAP-positive cells in the paraclaustral reservoir are simila...
journal_title:Acta neurobiologiae experimentalis
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更新日期:2001-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
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更新日期:2005-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
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journal_title:Acta neurobiologiae experimentalis
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doi:
更新日期:2004-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
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pub_type: 临床试验,杂志文章
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