Abstract:
:A term "paralytic tremor" (pt) is attributed to a neurological mutation of Chinchilla rabbits, affecting the development of the central nervous system (CNS). A quantification of myelin protein content indicates the strong CNS hypomyelination during the development (1-120 postnatal days). SDS-PAGE electrophoresis of total brain homogenates, followed by immunoblotting, shows a reduced concentration of major myelin-connected proteins. MBP deficiency corresponds approximately to the level of the hypomyelination, whereas PLP expression is drastically reduced.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Sypecka J,Tosic M,Dolivo M,Domańska-Janik K,Matthieu JMsubject
Has Abstractpub_date
1993-01-01 00:00:00pages
281-4issue
1eissn
0065-1400issn
1689-0035journal_volume
53pub_type
杂志文章abstract::Clinical and immunopathological evidence support a potential role of inflammatory cytokines in Alzheimer's disease (AD). However, studies examining the association between cytokine gene polymorphisms and risk of developing AD yielded conflicting results. The objective of our study was to evaluate the association betwe...
journal_title:Acta neurobiologiae experimentalis
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