Abstract:
:In 6 normotensive Wistar-Kyoto (WKY) and 6 spontaneously hypertensive rats (SHRs) anesthetized with urethane and chloralose, paralyzed, artificially ventilated, vagotomized with carotid sinus nerves bilaterally cut, somatosympathetic reflex discharges were recorded in cervical and renal nerves by stimulating group II and III cutaneous afferents in the sural nerve. Only a long-circuited, late supraspinal component reflex discharge could be elicited. After averaging the responses evoked by random stimulation, the latency of the reflex discharge was significantly longer in the renal than in the cervical sympathetic nerve, equally in the WKY rat and in SHR. In WKY rats the peak of sympathetic discharge corresponded to early expiration, whereas in SHRs--to late inspiratory phase. The duration of the reflex discharge elicited in inspiration was greater in SHR than in WKY rats. In WKY rats stimuli applied during phrenic discharge produced a reflex response of longer latency and of reduced amplitude than those applied in expiration. In SHRs the latency of the reflex response in the sympathetic cervical nerve was shorter during inspiration than in expiratory phase. The timing of the sympathetic reflex responsiveness within respiratory cycle in SHR and in WKY rats corresponded to strain-dependent opposite respiratory synchronization pattern of the spontaneous sympathetic activity characterizing each strain. No respiratory modulation of the somatosympathetic reflex was observed in the renal nerve of SHR. It is concluded that both spontaneous and evoked sympathetic activity is synchronized differently in SHR and in WKY rats and this difference is both species- and strain-dependent.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Czyzyk-Krzeska MF,Trzebski Asubject
Has Abstractpub_date
1990-01-01 00:00:00pages
47-60issue
3eissn
0065-1400issn
1689-0035journal_volume
50pub_type
杂志文章abstract::Anxiety is a complex psychological state which happens after stressful life experiences. Many factors such as daily life events, neurotransmitter systems, and different brain areas could influence anxiety behavior in humans and animals. For example, opioids and androgens decrease anxiety behavior both in humans and an...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2020-01-01 00:00:00
abstract::The performance of well established avoidance response was tested in cats with developed, kindled, bioelectric hippocampal epileptic focus and complex partial and secondarily generalized seizures. The animals were trained before kindling to perform foreleg movement in response to clicks (conditioning stimulus) in orde...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Trimethyltin, an organic compound of tin, is a potent neurotoxicant of a mechanism of action yet to be uncovered. The neuropathological findings that trimethyltin causes selective hippocampal damage with several unique features, highly reminiscent of Ammon's horn sclerosis as a final result, have raised the possibilit...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::New features of actual choice behavior and effortful information processing in rats were demonstrated in an eight-arm radial maze through modifications of a matching-to-sample task. Two attempts were allowed for a squad of hooded Sprague-Dawley rats (n=7) for finding a reward in a testing phase of the task. The result...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Deprivation of patterned visual information, as in early onset congenital cataract patients, results in a severe impairment in global motion perception. Previously we reported a delayed maturation of the peripheral visual field representation in primary visual area 17, based on a 2-D DIGE screen for protein expression...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2017-01-01 00:00:00
abstract::The experiment concerned the functional specialization of brain hemispheres in recognizing faces expressing emotions in patients with focal brain damage of the left and right hemispheres and in persons without damage of the central nervous system. Three types of faces were presented: happy i.e. expressing positive emo...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::The Sgt1 protein was discovered in yeast but later it was found in other eucaryotic organisms, including plants and mammals. It was suggested that the Sgt1 protein plays a role in the CBF3 kinetochore and the SCF ubiquitin ligase complexes. Since the distribution, properties and functions of the mammalian Sgt1 have no...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Four experiments were carried out to study the development of the orienting response (OR) under different experimental conditions in the cat and rat. In Experiment I and II (cat) and Experiment IV (rat) classical CS-US pairing was used (with food, shock and water reinforcers, respectively). In Experiment III (cat) an ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::The effect of central, short-term melatonin administration on daily GnRH and LH secretion was studied in ewes during seasonal anestrus. Melatonin, in a total dose of 32 micrograms and the vehicle were perfused for 4 hours into the mediobasal hypothalamus/median eminence (MBH/ME). The mean GnRH concentration during per...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::In an effort to determine the plasticity of the proliferative matrix of the hippocampus in an adult rat to environmental manipulation, the following study was conducted. Fifteen adult male Long-Evans rats (6 months old at the start of the experiment) were placed into two different environments for 3 months. Seven anim...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Techniques (push-pull cannula, cup, brain ventricles perfusion) allowing estimation of the amount of the ACh released in vivo from the brain are described. The main attention is paid to biochemical, physiological and morphological factors influencing the amount of ACh released and available for estimation. Conditions ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Dogs were trained to perform an instrumental avoidance reflex of lifting and holding a limb above a pre-determined level to prevent or to interrupt painful stimulation of the same limb. A tone preceding the stimulation by 0.5 s served as the CS. During the CS the excitability of the motoneuronal pools involved in the ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::Hypothyroidism affects neuron population dynamics in the hippocampus of the adult rat, with neuronal damage as the main feature of its effect. This effect is prevented by the blockade of NMDA receptors, which suggests that glutamatergic activity mediates cell death in this condition. Glutamate can also stimulate cell ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract::Temporal information processing controls many aspects of human mental activity and may be assessed by examining perception of temporal order in the tens of milliseconds time range. Although existing studies suggest an age-related decline in mental abilities, the data on the deterioration of temporal order perception s...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::The influence of bilateral injections of serotonin (5-HT) and methysergide (MET) to antero-medial hypothalamus (HA) on carbachol-induced emotional-defensive behavior was investigated. Earlier (15 min) stimulation of 5-HT receptors in HA region by 5-HT injections evoked a decrease in the level of vocal response (number...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::The noble gas xenon (Xe) inhibits not only NMDA receptors (NMDARs) but also the two other subtypes of glutamate receptor i.e. AMPA (AMPARs) and kainate receptors. Preliminary studies on AMPARs suggest that Xe sensitivity might be coupled to receptor desensitization. In order to find out if this hypothesis can be appli...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Cholinesterase inhibitors are currently the mainstream of symptomatic treatment of patients with Alzheimer's disease. The response to treatment with cholinesterase inhibitors is clinically difficult to predict. Several demographic, clinical and biological variables have been proposed as pretreatment predictors of long...
journal_title:Acta neurobiologiae experimentalis
pub_type: 临床试验,杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::In laboratory rats an epileptic-like spontaneous neocortical activity in the form of bursts of spike and wave discharges (SWD) develops gradually with age. High incidence of the SWD episodes is accompanied by other indices characteristic of advanced age: memory disturbances and atrophic changes within basal forebrain ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Quercetin, one of the major flavonoids, exhibits many beneficial effects on human organism as antihistamine, antioxidant, anti-inflammatory, anticancer and antiviral drug. It is recommended as supplement of healthy diet but still the knowledge of its beneficial effect on normal cells is not satisfactory. We decided to...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::A new method of investigating animal locomotion is presented which allows for the simultaneous measurement of the basic overground locomotion parameters: swing and stance durations, stride lengths, velocity of movement, gait diagrams and temporal relationships between all animal limbs. The measurements and recordings ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::As investigation has been made of the adequacy of direct current to block conduction in the myelinated fibres of the cervical vagus nerve, leaving the nonmyelinated fibres conducting normally. Conduction was assessed from the compound electroneurograms, and from single fibre recording. Conduction of spontaneous activi...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::Poly (lactide‑co‑glycolide) (PLGA) nanoparticles (NPs) are biodegradable carriers that participate in the transport of neuroprotective drugs across the blood brain barrier (BBB). Targeted brain‑derived neurotrophic factor (BDNF) delivery across the BBB could provide neuroprotection in brain injury. We tested the neuro...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2020-01-01 00:00:00
abstract::During the first two postnatal weeks postural reflexes were either absent or abortive. First adult-like patterns of reactions were seen at the end of the 3rd week but they could be regularly elicited only by the 6th-9th week. ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Clinical and immunopathological evidence support a potential role of inflammatory cytokines in Alzheimer's disease (AD). However, studies examining the association between cytokine gene polymorphisms and risk of developing AD yielded conflicting results. The objective of our study was to evaluate the association betwe...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::Functional interactions between serotoninergic and GABAergic systems in the vertebrate retina are largely unknown. In this study, the effects of isolated or combined stimulation of the serotonin receptors (with 100 μM serotonin) and ionotropic GABAA and GABAC receptors (with 5 mM TACA) on the electroretinographic (ERG...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2017-01-01 00:00:00
abstract::Huntington's disease is an autosomal dominant progressive neurodegenerative disease, which results in a decreased quality of life and an early death. A high prevalence of vitamin D deficiency was first described in a 2013 study in patients with manifest Huntington's disease, where serum vitamin D level was found to be...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:10.21307/ane-2017-017
更新日期:2016-01-01 00:00:00
abstract::In the present study the functional role of SH groups in the Ca(2+)-independent K(+)-selective channel activity in the membrane of bovine adrenal gland chromaffin granules has been studied. Ionic channel activity has been estimated using 86Rb+, a K+ analogue, flux measurements. The inhibition of chromaffin granules K+...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::We have studied MHC class II antigen expression and lymphocytic infiltration during dopaminergic neurone degeneration produced by intoxication with 1-methyl-4-phenyl-1,2,3,6-tetrahydropiridine (MPTP). Microglial activation was observed in the striatum and in the substantia nigra (SN) in this model. We noticed a marked...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Adult mammalian brain contains a number of specialized neurovascular structures termed "niches" that act as sources of neuronal cells throughout the individual's life. Some of the niches generate neurons to satisfy the need for 'replacement' neurons within the same or closely located brain structures, whereas the othe...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:10.21307/ane-2017-012
更新日期:2016-01-01 00:00:00
abstract::A new hypothesis concerning the mechanism of the P. rufescens' slave-raids, is proposed. (i) The so-called pseudo-scouting does not contribute to the slave-raids. (ii) The direction of the raid is determined by the random movement of the most easily aroused individuals - the so-called activists. (iii) Once the directi...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00