Abstract:
:The purpose of this study was to determine if the contribution of a muscle to an increase in VT remained the same regardless of the chemical stimulus used to provoke the increase. In seven anaesthetized cats one phrenic nerve was transected and placed on platinum electrodes. The activity was rectified and integrated. After a control period the cat was given either an 8 percent CO2 in air or an 8-10 percent O2 mixture to breathe for 30-45 breaths until a relatively constant VT appeared. Phrenic nerve activity/time (PE) was correlated with tidal volume (VT) for each breath. The linear correlation coefficient (r) for the hypercapnic response was 0.958; for the hypoxic response it was 0.858. The slope of the hypercapnic response (PE, VT) was 0.0619 while that for hypoxia was 0.0379. The rate of phrenic nerve activity was significantly more responsible for the generation of an increase in VT than was the duration of the phrenic burst. And the relative contribution of each was significantly different for the two different stimuli. These results suggest that when equal VT is demanded in response to hypercapnia or hypoxia, the diaphragm is less active in generating the increase in VT during hypercapnia. Or if the diaphragm contracts equally in generating equal VT's, more neural energy per unit time is required if the stimulus is hypoxia.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Fitzgerald RSsubject
Has Abstractpub_date
1973-01-01 00:00:00pages
419-25issue
1eissn
0065-1400issn
1689-0035journal_volume
33pub_type
杂志文章abstract::With the development of new therapeutic strategies, and the concept of mild cognitive impairment (MCI) as an early stage of Alzheimer's disease (AD), there is an increasing need for an early and accurate diagnosis of sporadic AD. Therefore, biological markers allowing a positive diagnosis early in the course of the di...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2004-01-01 00:00:00
abstract::The aim of the present study was to investigate the effect of small unilateral lesions to the ventromedial portion of the prefrontal cortex on two memory functions: memory for objects and memory for object locations. Patients, who had undergone surgery of the anterior communicating artery aneurysm, and normal control ...
journal_title:Acta neurobiologiae experimentalis
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更新日期:2003-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
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doi:10.21307/ane-2017-017
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:1974-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Abnormal auditory temporal processing might be an underlying deficit in language disabilities. The auditory temporal-order threshold, one measure for temporal processing abilities, is defined as the shortest time interval between two acoustic events necessary for a person to be able to identify the correct temporal or...
journal_title:Acta neurobiologiae experimentalis
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Lesions in ventromedial part of amygdala impaired neither alimentary instrumental reflexes nor food intake, but impaired predatory behavior. Lesions localized in the more dorsal and lateral part of the amygdala produced disorders in instrumental performance and food intake without changes in predatory attack. Both kin...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Dorsal prefrontal lesions in dogs elicit hyperreactivity in instrumental discrimination and perseveration in trained serial action pattern. Lateral premotor injury causes hyporeactivity in instrumental discrimination and prolongation of activity in the trained serial action pattern. When the dorsal prefrontal area was...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
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doi:
更新日期:2011-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
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pub_type: 杂志文章,评审
doi:
更新日期:2019-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1974-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
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doi:
更新日期:2012-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1974-01-01 00:00:00
abstract::Poly (lactide‑co‑glycolide) (PLGA) nanoparticles (NPs) are biodegradable carriers that participate in the transport of neuroprotective drugs across the blood brain barrier (BBB). Targeted brain‑derived neurotrophic factor (BDNF) delivery across the BBB could provide neuroprotection in brain injury. We tested the neuro...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2020-01-01 00:00:00
abstract::In four dogs instrumental defensive conditioned reflexes to direct electrical stimulation of the hippocampus were elaborated. After reaching 60 percent CR performance, unreinforced stimulations of several limbic structures were given to test generalization. Positive generalization was more frequent than negative one. ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2018-01-01 00:00:00
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journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00