Abstract:
:Twenty five animals trained in the left leg-right leg differentiation were given orbital, proreal or medial precruciate lesions. Pure cortical ablations did not affect the task whereas these deep lesions involving the bundle of fibers inside the prefrontal region caused severe deficit. The medial lesions (superficial and deep) produced disinhibition of the intertrial reactions. The nature of the deficit in the differentiation and the relation between this deficit and the disinhibition is discussed.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Stepień I,Stepień Lsubject
Has Abstractpub_date
1972-01-01 00:00:00pages
331-43issue
2eissn
0065-1400issn
1689-0035journal_volume
32pub_type
杂志文章abstract::Adult mammalian brain contains a number of specialized neurovascular structures termed "niches" that act as sources of neuronal cells throughout the individual's life. Some of the niches generate neurons to satisfy the need for 'replacement' neurons within the same or closely located brain structures, whereas the othe...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:10.21307/ane-2017-012
更新日期:2016-01-01 00:00:00
abstract::Time characteristics of lateral-hypothalamic self-stimulation were analyzed in rats using point process statistics. Inter-barpressing interval distributions were usually unimodal and asymmetrical and resembled shifted exponential distribution, i.e. bar-pressings seem to be performed more or less randomly over time. Wh...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Our work assesses the effects of mu opioid receptor activation on high-threshold Ca2+/Ba2+ currents in freshly dispersed pyramidal neurons of the medial prefrontal cortex in rats. Application of the specific mu receptor agonist (D-Ala2+, N-Me-Phe4+, Gly5+-ol)-enkephalin (DAMGO) at 1 microM decreased Ca2+ current ampli...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::The aim of the present study was to investigate the effect of small unilateral lesions to the ventromedial portion of the prefrontal cortex on two memory functions: memory for objects and memory for object locations. Patients, who had undergone surgery of the anterior communicating artery aneurysm, and normal control ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::Working memory is an ability to keep information in short-term memory and manipulate them 'on line'. Working memory is also involved in complex frontal executive functions. The role of dopaminergic system in modulating working memory processes in prefrontal cortex is well established. Also the role of serotoninergic r...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::It is well-known that the cholinergic system and the muscarinic cholinergic receptors are associated with cognitive functions. Here we examined whether a non-selective muscarinic receptor antagonist scopolamine affects learning performance and/or synaptic plasticity during the memory consolidation period. Adult male W...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract::Frontal rats, subjected to electroconvulsive shock (ECS) after each experimental session, performed better than they did before ECS treatment. The other subjects, which were treated with ECS after every third session, showed lower error scores on days immediately folloiwing ECS administration that 2 or 3 days later. W...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
abstract::Sham operated controls and four groups of rats subjected to ablation of various parts of their frontal cortex were compared in food and water intake and four behavioural tasks. The ablations were aimed at removing (1) the ventral prefrontal cortex, (2) the dorsal part of the medial prefrontal cortex, (3) the total med...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Disturbances of enteric nerve-mediated anorectal evacuation mechanisms have medical and social impact. The study aimed at further eliciting the contribution of cholinergic and nitrergic neurotransmission systems to modular nerve networks in different regions of Wistar rat anorectum. Electrical field stimulation (EFS, ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::All myelinated fibres along the unbranched pant of the phrenic nerve were teased and measured at regular intervals. At the proximal level, the size frequency distribution is bimodal with peaks at 2 and 7 micrometers. Fibres in most size classes exhibit a slight progressive tapering along their unbranched course in the...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1974-01-01 00:00:00
abstract::Embedment-free electron microscopy (EFEM) is a new method which allows the visualisation of cytoskeleton in whole-mounted cells. In this study we employed EFEM to investigate the structure of cellular scaffolds in glioma C6 cell line. The cells were extracted with Triton X-100 that dissolves phospholipids in the membr...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Twenty-two rats were reared in standard conditions during the first two months of their life. Then the animals were divided into two groups exposed to different rearing conditions. Twelve animals (Group SO) were housed socially, six animals per cage, and for three weeks they were subjected to sensory stimulation in an...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::The variability of simple actions with response to auditory stimuli was studied under different delay conditions. Subjects reacted as fast as possible or with a defined time delay (from 250 to 750 ms) to a tone switching off by pressing a response-key with the left index finger (controlled by the right hemisphere) or ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Twenty two months old and eight months old rats were used. They were submitted to object recognition test with 1 min interval between two successive presentations of the same object or two different objects. Initial exploration of the object was lower in aged than in young rats. However, both groups showed comparable ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The activity of the biceps brachii and lateral head of the triceps brachii were compared during the contact placing reactions elicited by tactile stimuli applied to the lateral, medial or dorsal aspects of the forepaw to verify the hypothesis that common movement strategy was used in all these reactions. Similar laten...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Eight cats were binocularly deprived of pattern vision by rearing in masks from the time of eye opening. Twenty five groups of 3 neurons and 28 neuronal pairs were studied in visual orientation columns of their striate cortices. The crosscorrelograms of neuronal discharges were analyzed and the inference of underlying...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The superior colliculus has been implicated in visual orientation and localization in several mammalian species. To examine this possibility in rhesus monkeys, we trained monkeys to respond to one of six locations signaled by a small light of 5 s duration that was turned off immediately before they were allowed to res...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Electrical activity of hippocampus was investigated in cats in the delayed response situation by comparing spectral analysis and integration of electrohippocampogram rhythms in different stages of delayed response performance. In addition, electrical stimulation of lateral and ventromedial hypothalamic nuclei was used...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
abstract::Connnections of the cortical region situated in the medial and lateral walls of the presylvian fissure in the dog were investigated using the method of retrograde HRP transport. The patterns of subcortico-cortical and cortico-cortical projections sho,w that the cortical field of the medial presylvian wall (paraorbital...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The neurocognitive consequences of correct or incorrect spatial prediction in a sequential S1-S2 paradigm were assessed. Sequential dependence on previous trial outcome (valid or invalid) was assessed by late Event-Related Potentials (ERPs) and behavioral responses. Two different experiments were performed, situating ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Persons with trisomy 21 (Down syndrome) present different phenotypes, including early neurodegeneration, which is prominent in the brain olfactory areas, and olfactory deficit. The use of in vivo techniques in animal models allows to characterize and follow up these slowly developing phenomena. We explored by means of...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2020-01-01 00:00:00
abstract::A change in feeding behavior on the 15th and 16th day of the maternal cycle was observed in experimental bitches whose own litter was partly replaced, on the onset of the 15th day, by foster puppies 12-13 days younger. The number of feeding acts and the overall feeding time increased, as compared with the indices for ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract:INTRODUCTION AND METHODS:Cognitive deficits in insomnia have been already reported (5), however, a correlation between cognitive impairment and severity of insomnia was not as yet studied. Sixteen not medicated patients with primary insomnia according to DSM-IV (4), 7 men an 9 women, of mean age 40.8 year, were compare...
journal_title:Acta neurobiologiae experimentalis
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Clinical and immunopathological evidence support a potential role of inflammatory cytokines in Alzheimer's disease (AD). However, studies examining the association between cytokine gene polymorphisms and risk of developing AD yielded conflicting results. The objective of our study was to evaluate the association betwe...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::Dogs were trained to perform an instrumental avoidance reflex of lifting and holding a limb above a pre-determined level to prevent or to interrupt painful stimulation of the same limb. A tone preceding the stimulation by 0.5 s served as the CS. During the CS the excitability of the motoneuronal pools involved in the ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::Signal integration in neurons is a complex process that depends on e.g. the kinetics of synaptic currents, distribution of synaptic connections as well as passive and excitatory membrane properties. The time course of synaptic currents is largely determined by the kinetics of the postsynaptic receptors and the time co...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
abstract::The mammalian pineal organ contains photoreceptor-specific proteins, whose distribution shows conspicuous variation among different species of mammals. Nevertheless, the following general conclusions can be drawn: immunoreactions for S-antigen and recoverin labeled more pinealocytes than the rod-opsin immunoreaction. ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::In this study I attempted to assess, in rats, the role of AT1 and AT2 angiotensin receptor subtypes in the phenomenon of improved learning and memory after an intracerebroventricular (icv) injection of angiotensin II (Ang II) and Ang II (3-7). Selective AT1 (losartan, 1 mg) or AT2 (CGP 42112 A, 2 micrograms) receptor ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Vocalization and eye movements during emotional-defensive response evoked by unilateral intrahypothalamic carbachol injections (10 micrograms) were quantitatively determined. The growling episodes duration paralleled the development and the subsiding of the defensive behavior, while the changes of eye movements indica...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::The involvement of calcium ions in mechanisms of ischemic brain injury has been suggested for several years. Our understanding of the role of intracellular Ca2+ as a trigger of acute neurotoxicity and in the induction of long lasting processes leading to necrotic and/or apoptotic postischemic delayed neuronal death or...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00