Helper-dependent properties of Friend spleen focus-forming virus: effect of the Fv-1 gene on the late stages in virus synthesis.

abstract：:From purified linear and superhelical DNAs, the restriction endonuclease maps of four xenotropic murine leukemia virus DNAs from NFS, NZB, BALB/c, and AKR mice were determined with ten restriction endonucleases. Each xenotropic proviral DNA was found to be a unique restriction endonuclease map, with differences in the...

journal_title：Journal of virology

authors： Joseph DR

更新日期：1981-12-01 00:00:00

abstract：:Interactions between host factors and the viral replication complex play important roles in host adaptation and regulation of influenza virus replication. A cellular protein, nuclear factor 90 (NF90), was copurified with H5N1 viral nucleoprotein (NP) from human cells in which NP was transiently expressed and identifie...

journal_title：Journal of virology

authors： Wang P,Song W,Mok BW,Zhao P,Qin K,Lai A,Smith GJ,Zhang J,Lin T,Guan Y,Chen H

更新日期：2009-08-01 00:00:00

abstract：:The adjuvant effects of cytokines in humoral and cell-mediated immunity to herpes simplex virus type 1 (HSV-1) have been examined in mice using HSV-1 recombinant viruses expressing murine interleukin-2 (IL-2), IL-4, or gamma interferon (IFN-gamma) gene. Groups of naive BALB/c mice were immunized intraperitoneally with...

journal_title：Journal of virology

authors： Osorio Y,Ghiasi H

更新日期：2003-05-01 00:00:00

abstract：:p60src, the transforming protein of Rous sarcoma virus, was found to contain 0.5 to 0.9 mol of total phosphate per mol of polypeptide. The protein is known to be phosphorylated at two sites, a serine in the amino-terminal domain and a tyrosine in the carboxy-terminal domain. Because our indirect analysis suggests that...

journal_title：Journal of virology

authors： Sefton BM,Patschinsky T,Berdot C,Hunter T,Elliott T

更新日期：1982-03-01 00:00:00

abstract：:Worldwide amphibian population declines have been ascribed to global warming, increasing pollution levels, and other factors directly related to human activities. These factors may additionally be favoring the emergence of novel pathogens. In this report, we have determined the complete genome sequence of the emerging...

journal_title：Journal of virology

authors： Mavian C,López-Bueno A,Balseiro A,Casais R,Alcamí A,Alejo A

更新日期：2012-04-01 00:00:00

abstract：:We have examined the influence of the V1/V2 region of the human immunodeficiency virus type 1 (HIV-1) gp120 on certain biologic properties of the virus. We observed that on the genomic background of the T-cell-line-tropic strain, HIV-1SF2mc, both the V1 and V2 domains of the macrophage-tropic strain, HIV-1SF162mc, in ...

journal_title：Journal of virology

authors： Koito A,Harrowe G,Levy JA,Cheng-Mayer C

更新日期：1994-04-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) glycoprotein US2 increases the proteasome-mediated degradation of major histocompatibility complex (MHC) class I heavy chain (HC), class II DR-alpha and DM-alpha proteins, and HFE, a nonclassical MHC protein. US2-initiated degradation of MHC proteins apparently involves the recruitment of ...

journal_title：Journal of virology

authors： Chevalier MS,Johnson DC

更新日期：2003-04-01 00:00:00

abstract：:The papillomavirus E2 protein is a critical viral regulatory protein with transcription, DNA replication, and genome maintenance functions. We have previously identified the cellular bromodomain protein Brd4 as a major E2-interacting protein and established that it participates in tethering bovine papillomavirus type ...

journal_title：Journal of virology

authors： Schweiger MR,Ottinger M,You J,Howley PM

更新日期：2007-09-01 00:00:00

abstract：:Selecting human immunodeficiency virus (HIV) sequences for inclusion within vaccines has been a difficult problem, as circulating HIV strains evolve relentlessly and become increasingly divergent over time. We report an assessment of this divergence from three perspectives: (i) across different hosts as a function of ...

journal_title：Journal of virology

authors： Herbeck JT,Nickle DC,Learn GH,Gottlieb GS,Curlin ME,Heath L,Mullins JI

更新日期：2006-02-01 00:00:00

abstract：:The ribonucleic acid (RNA) of murine leukemia virus (MLV) Rauscher strain was observed by the aid of electron microscopy with the use of the protein monolayer technique. RNA was observed directly after release from virus particles or after isolation by sedimentation in sucrose density gradients. Molecules were found i...

journal_title：Journal of virology

authors： Kakefuda T,Bader JP

更新日期：1969-10-01 00:00:00

abstract：:Treatment of [3H]glucosamine-labeled Friend mink cell focus-forming virus (FrMCF) gp70 with excess peptide:N-glycanase F (PNGase F) resulted in removal of the expected seven N-linked oligosaccharide chains; however, approximately 10% of the glucosamine label was retained in the resulting 49,000-Mr (49K) product. For [...

journal_title：Journal of virology

authors： Pinter A,Honnen WJ

更新日期：1988-03-01 00:00:00

abstract：:Herpes simplex virus VP22 is a major tegument protein of unknown function. Very recently, we reported that the predominant effect of deleting the VP22 gene was on the expression, localization, and virion incorporation of ICP0. In addition, the Delta22 virus replicated poorly in epithelial MDBK cells. We have also prev...

journal_title：Journal of virology

authors： Potel C,Elliott G

更新日期：2005-11-01 00:00:00

abstract：:Herpesviruses use a cascade of interactions with different cell surface molecules to gain entry into cells. In many cases, this involves binding to abundant glycosaminoglycans or integrins followed by interactions with more limited cell surface proteins, leading to fusion with cellular membranes. Human cytomegalovirus...

journal_title：Journal of virology

authors： Vanarsdall AL,Ryckman BJ,Chase MC,Johnson DC

更新日期：2008-12-01 00:00:00

abstract：:Galectin-9 is a pleiotropic immune modulator affecting numerous cell types of innate and adaptive immunity. Patients with chronic infection with either hepatitis C virus (HCV) or HIV have elevated circulating levels. Limited data exist on the regulation of natural killer (NK) cell function through interaction with gal...

journal_title：Journal of virology

authors： Golden-Mason L,McMahan RH,Strong M,Reisdorph R,Mahaffey S,Palmer BE,Cheng L,Kulesza C,Hirashima M,Niki T,Rosen HR

更新日期：2013-05-01 00:00:00

abstract：:Inclusion bodies are a characteristic feature of ebolavirus infections in cells. They contain large numbers of preformed nucleocapsids, but their biological significance has been debated, and they have been suggested to be aggregates of viral proteins without any further biological function. However, recent data for o...

journal_title：Journal of virology

authors： Hoenen T,Shabman RS,Groseth A,Herwig A,Weber M,Schudt G,Dolnik O,Basler CF,Becker S,Feldmann H

更新日期：2012-11-01 00:00:00

abstract：:When ts7, a temperature-sensitive (ts) mutant of influenza B/Kanagawa/73 virus, infected MDCK cells at the nonpermissive temperature (37.5 degrees C), infectious virus was produced at very low levels compared with the yield at the permissive temperature (32 degrees C) and hemagglutinating activity and enzymatic activi...

journal_title：Journal of virology

authors： Yamamoto-Goshima F,Maeno K,Morishita T,Ueda M,Fujita Y,Nakajima K,Yoshii S

更新日期：1994-02-01 00:00:00

abstract：:Mitochondria are important for the viral life cycle, mainly by providing the energy required for viral replication and assembly. A highly complex interaction with mitochondria is exerted by rubella virus (RV), which includes an increase in the mitochondrial membrane potential as a general marker for mitochondrial acti...

journal_title：Journal of virology

authors： Claus C,Schönefeld K,Hübner D,Chey S,Reibetanz U,Liebert UG

更新日期：2013-08-01 00:00:00

abstract：:Viral myocarditis is an important human disease, and reovirus-induced murine myocarditis provides an excellent model system for study. Cardiac myocytes, like neurons in the central nervous system, are not replenished, yet there is no cardiac protective equivalent to the blood-brain barrier. Thus, cardiac myocytes may ...

journal_title：Journal of virology

authors： Zurney J,Howard KE,Sherry B

更新日期：2007-12-01 00:00:00

abstract：:We previously demonstrated that polyhedron formation (PF) mutants arise at a high frequency during serial passage of the Lymantria dispar nucleopolyhedrovirus (LdMNPV) in the L. dispar 652Y cell line (J. M. Slavicek, N. Hayes-Plazolles, and M. E. Kelly, Biol. Control 5:251-261, 1995). Most of these PF mutants exhibite...

journal_title：Journal of virology

authors： Bischoff DS,Slavicek JM

更新日期：1997-02-01 00:00:00

abstract：:An important site for bovine herpesvirus 1 (BoHV-1) latency is sensory neurons within trigeminal ganglia (TG). The synthetic corticosteroid dexamethasone consistently induces BoHV-1 reactivation from latency. Expression of four Krüppel-like transcription factors (KLF), i.e., KLF4, KLF6, PLZF (promyelocytic leukemia zi...

journal_title：Journal of virology

authors： El-Mayet FS,Sawant L,Thunuguntla P,Zhao J,Jones C

更新日期：2020-01-31 00:00:00

abstract：:A distinct clinical presentation of respiratory syncytial virus (RSV) infection of humans is bronchiolitis, which has clinical features similar to those of asthma. Substance P (SP), a tachykinin neuropeptide, has been associated with neurogenic inflammation and asthma; therefore, we chose to examine SP-induced inflamm...

journal_title：Journal of virology

authors： Tripp RA,Moore D,Winter J,Anderson LJ

更新日期：2000-02-01 00:00:00

abstract：:In response to viral infection, host cells elicit a number of responses, including the expression of alpha/beta interferon (IFN-alpha/beta). In these cells, IFN regulatory factor-3 (IRF-3) undergoes a sequence of posttranslational modifications that allow it to act as a potent transcriptional coactivator of specific I...

journal_title：Journal of virology

authors： Melroe GT,DeLuca NA,Knipe DM

更新日期：2004-08-01 00:00:00

abstract：:The techniques of deoxyribonucleic acid-ribonucleic acid (DNA-RNA) hybridization and immunological precipitation were used to compare the synthesis of adenovirus-specific macromolecules in African green monkey kidney (AGMK) cells infected with adenovirus, an abortive infection, and coinfected with both adenovirus and ...

journal_title：Journal of virology

authors： Lucas JJ,Ginsberg HS

更新日期：1972-12-01 00:00:00

abstract：:Human immunodeficiency virus clade C (HIV-C) accounts for >56% of all HIV infections worldwide. To investigate vaccine safety and efficacy in nonhuman primates, a pathogenic, R5-tropic, neutralization-sensitive simian-human immunodeficiency virus (SHIV) carrying HIV-C env would be desirable. We have constructed SHIV-2...

journal_title：Journal of virology

authors： Siddappa NB,Song R,Kramer VG,Chenine AL,Velu V,Ong H,Rasmussen RA,Grisson RD,Wood C,Zhang H,Kankasa C,Amara RR,Else JG,Novembre FJ,Montefiori DC,Ruprecht RM

更新日期：2009-02-01 00:00:00

abstract：:Similar to other positive-sense, single-stranded RNA viruses, hepatitis C virus (HCV) replicates its genome in a remodeled intracellular membranous structure known as the membranous web (MW). To date, the process of MW formation remains unclear. It is generally acknowledged that HCV nonstructural protein 4B (NS4B) can...

journal_title：Journal of virology

authors： Xu S,Pei R,Guo M,Han Q,Lai J,Wang Y,Wu C,Zhou Y,Lu M,Chen X

更新日期：2012-12-01 00:00:00

abstract：:Vaccine-elicited humoral immune responses comprise an array of antibody forms and specificities, with only a fraction contributing to protective host immunity. Elucidation of antibody effector functions responsible for protective immunity against human immunodeficiency virus type 1 (HIV-1) acquisition is a major goal ...

journal_title：Journal of virology

authors： Wills S,Hwang KK,Liu P,Dennison SM,Tay MZ,Shen X,Pollara J,Lucas JT,Parks R,Rerks-Ngarm S,Pitisuttithum P,Nitayapan S,Kaewkungwal J,Thomas R,Kim JH,Michael NL,Robb ML,McRaven M,Montefiori DC,Hope TJ,Liao HX,Mood

更新日期：2018-03-14 00:00:00

abstract：:Understanding the microbiome of ticks in Australia is of considerable interest given the ongoing debate over whether Lyme disease and its causative agent, the bacterium Borrelia burgdorferisensu lato, are present in Australia. The diversity of bacteria infecting Australian ticks has been studied using both culture- an...

journal_title：Journal of virology

authors： Harvey E,Rose K,Eden JS,Lo N,Abeyasuriya T,Shi M,Doggett SL,Holmes EC

更新日期：2019-01-17 00:00:00

abstract：:The insertion of a particular phi X DNA sequence in the plasmid pACYC177 strongly decreased the capacity of Escherichia coli cells containing such a plasmid to propagate bacteriophage phi X174. The smallest DNA sequence tested that showed the effect was the HindII fragment R4. This fragment does not code for a complet...

journal_title：Journal of virology

authors： van der Avoort HG,van Arkel GA,Weisbeek PJ

更新日期：1982-04-01 00:00:00

abstract：:Extrachromosomal DNA was isolated from tissue culture cells that were acutely infected with simian sarcoma virus (SSV) and its associated helper (simian sarcoma-associated virus [SSAV]). Two sizes of closed circular viral genomic DNA intermediates were isolated, cleaved at the single EcoRI site, and ligated to the Cha...

journal_title：Journal of virology

authors： Gelmann EP,Petri E,Cetta A,Wong-Staal F

更新日期：1982-02-01 00:00:00

abstract：:Genotype 1 hepatitis E viruses (HEVs) are restricted to primate hosts, whereas genotype 3 HEVs predominantly infect swine, in addition to primates. In order to identify possible determinants of the host range, infectious recombinant viruses and chimeras of a genotype 1 isolate and a genotype 3 isolate were compared fo...

journal_title：Journal of virology

authors： Nguyen HT,Shukla P,Torian U,Faulk K,Emerson SU

更新日期：2014-01-01 00:00:00