Comparison of the restriction endonuclease maps of unintegrated proviral DNAs from four xenotropic murine leukemia viruses.

abstract：:Because immunologic classification of human immunodeficiency virus type 1 (HIV) might be more relevant than genotypic classification for designing polyvalent vaccines, studies were undertaken to determine whether immunologically defined groups of HIV ("immunotypes") could be identified. For these experiments, the V3 r...

journal_title：Journal of virology

authors： Zolla-Pazner S,Gorny MK,Nyambi PN,VanCott TC,Nádas A

更新日期：1999-05-01 00:00:00

abstract：:The mechanism by which bovine herpesvirus 1 (BHV-1) predisposes cattle to bacterial pneumonia was investigated by using an in vitro system to demonstrate immunosuppression. At a multiplicity of infection of 0.001, live or inactivated BHV-1 induced a 50% inhibition of the proliferative response of peripheral blood mono...

journal_title：Journal of virology

authors： Hutchings DL,Campos M,Qualtiere L,Babiuk LA

更新日期：1990-09-01 00:00:00

abstract：:The Moloney murine leukemia virus (MuLV) is a highly leukemogenic virus. To map the leukemogenic potential of Moloney MuLV, we constructed chimeric viral DNA genomes in vitro between parental cloned infectious viral DNA from Moloney and amphotropic 4070-A MuLVs. Infectious chimeric MuLVs were recovered by microinjecti...

journal_title：Journal of virology

authors： DesGroseillers L,Jolicoeur P

更新日期：1984-11-01 00:00:00

abstract：:The innate immune response is crucial for defense against viral infections. Cells recognize virus infection through pattern recognition receptors and induce type I interferons as well as proinflammatory cytokines to orchestrate an innate immune response. Herpes simplex virus 1 (HSV-1) triggers both the cyclic GMP-AMP ...

journal_title：Journal of virology

authors： Latif MB,Raja R,Kessler PM,Sen GC

更新日期：2020-02-28 00:00:00

abstract：:Interactions between host factors and the viral replication complex play important roles in host adaptation and regulation of influenza virus replication. A cellular protein, nuclear factor 90 (NF90), was copurified with H5N1 viral nucleoprotein (NP) from human cells in which NP was transiently expressed and identifie...

journal_title：Journal of virology

authors： Wang P,Song W,Mok BW,Zhao P,Qin K,Lai A,Smith GJ,Zhang J,Lin T,Guan Y,Chen H

更新日期：2009-08-01 00:00:00

abstract：:The classical swine fever virus (CSFV) live attenuated vaccine C-strain is adaptive to rabbits and attenuated in pigs, in contrast with the highly virulent CSFV Shimen strain. Previously, we demonstrated that P108 and T109 on the E2 glycoprotein (E2P108-T109) in domain I (E2DomainI) rather than R132, S133, and D191 in...

journal_title：Journal of virology

authors： Xie L,Han Y,Ma Y,Yuan M,Li W,Li LF,Li M,Sun Y,Luo Y,Li S,Hu S,Li Y,Qiu HJ

更新日期：2020-08-17 00:00:00

abstract：:Subcutaneous injection of FK506 (10 mg/kg of body weight) completely blocked the clonal expansion of staphylococcal enterotoxin A (SEA)-reactive T cells in healthy (control) mice after SEA injection but did not disturb it in mice with murine AIDS (MAIDS) caused by infection with LP-BM5 murine leukemia virus. MAIDS mic...

journal_title：Journal of virology

authors： Yoshikai Y,Kidokoro H,Kimura K,Aoki Y,Makino M,Hiromatsu K

更新日期：1997-01-01 00:00:00

abstract：:A more complete assessment of ovine prion strain diversity will be achieved by complementing biological strain typing in conventional and ovine PrP transgenic mice with a biochemical analysis of the resultant PrPSc. This will provide a correlation between ovine prion strain phenotype and the molecular nature of differ...

journal_title：Journal of virology

authors： Thackray AM,Hopkins L,Spiropoulos J,Bujdoso R

更新日期：2008-11-01 00:00:00

abstract：:The level of RNase activity in human interferon preparations was examined. Although sequential purification of interferon resulted in nearly a 300-fold increase in specific activity, RNase-specific activity remained more or less constant. The implications of this finding for the analyses of the mode of action of inter...

journal_title：Journal of virology

authors： Winchurch RA,Karpetsky TP,Levy CC,Cantell K

更新日期：1977-03-01 00:00:00

abstract：:Interferons (IFNs) are a critical component of the first line of antiviral defense. The activation of Toll-like receptors (TLRs) expressed by dendritic cells triggers different signaling cascades that result in the production of large amounts of IFNs. However, the functional consequences of TLR activation and differen...

journal_title：Journal of virology

authors： Ioannidis I,Ye F,McNally B,Willette M,Flaño E

更新日期：2013-03-01 00:00:00

abstract：:Upon immunization and restimulation with tumors induced by the endogenous AKR/Gross murine leukemia virus (MuLV), C57BL/6 mice generate vigorous H-2K(b)-restricted cytotoxic T-lymphocyte (CTL) responses to a determinant (KSPWFTTL) derived from the p15E transmembrane portion of the viral envelope glycoprotein. By contr...

journal_title：Journal of virology

authors： Kim V,Yewdell JW,Green WR

更新日期：2000-04-01 00:00:00

abstract：:Vaccine-induced memory is necessary for protective immunity to pathogens, but many viruses induce a state of transient immune suppression that might contribute to the inability of a vaccine to elicit immunity. We evaluated here the fate of bystander T cells activated by third party cognate antigens during acute viral ...

journal_title：Journal of virology

authors： Marshall HD,Urban SL,Welsh RM

更新日期：2011-06-01 00:00:00

abstract：:Caprine arthritis encephalitis virus (CAEV) is a lentivirus closely related to visna virus and more distantly to other lentiviruses, such as human immunodeficiency virus. The genomes of visna virus and CAEV contain a tat gene encoding a protein able to weakly transactivate its own long terminal repeat, suggesting that...

journal_title：Journal of virology

authors： Harmache A,Vitu C,Russo P,Bouyac M,Hieblot C,Peveri P,Vigne R,Suzan M

更新日期：1995-09-01 00:00:00

abstract：:The presence of complement-fixing (CF) antibody reactive with T antigen and with viral C antigen in hamsters bearing adenovirus 12-induced tumors has been confirmed. Antibody activity in serum obtained at a time when the host was bearing large tumors was found to be associated exclusively with 7S immunoglobulins. Two ...

journal_title：Journal of virology

authors： Fugmann RA,Sigel MM

更新日期：1967-08-01 00:00:00

abstract：:The morphology and development of four members of the reticuloendotheliosis virus group were studied by transmission electron microscopy. Virions of duck spleen necrosis virus, duck infectious anemia virus, chicken syncytial virus, and reticuloendotheliosis virus strain T are sperical with a diameter of approximately ...

journal_title：Journal of virology

authors： Kang CY,Wong TC,Holmes KV

更新日期：1975-10-01 00:00:00

abstract：:Mutations critical for the central nervous system (CNS) attenuation of the Sabin vaccine strains of poliovirus (PV) are located within the viral internal ribosome entry site (IRES). We examined the interaction of the IRESs of PV type 3 (PV3) and Sabin type 3 (Sabin3) with polypyrimidine tract-binding protein (PTB) and...

journal_title：Journal of virology

authors： Guest S,Pilipenko E,Sharma K,Chumakov K,Roos RP

更新日期：2004-10-01 00:00:00

abstract：:PLC/PRF/5, a tissue culture cell line isolated from a human hepatocellular carcinoma and producing hepatitis B surface antigen, was studied for the presence of hepatitis B virus (HBV)-specific DNA and RNA. PLC/PRF/5 cell DNA accelerated the rate of reassociation of HBV [32P]DNA, and quantitative experiments indicated ...

journal_title：Journal of virology

authors： Marion PL,Salazar FH,Alexander JJ,Robinson WS

更新日期：1980-02-01 00:00:00

abstract：:RNA-dependent RNA polymerases were found to be associated with two salmonid rhabdoviruses: infectious hematopoietic necrosis (IHN) virus and the virus of hemorrhagic septicemia (VHS). The protein composition of these rhabdoviruses closely resembles that of rabies virus rather than that of vesicular stomatitis virus (M...

journal_title：Journal of virology

authors： McAllister PE,Wagner RR

更新日期：1977-06-01 00:00:00

abstract：:The occurrence of genome segment reassortment between two antigenically related orbiviruses was demonstrated in cattle. Individual virus clones were isolated by cell culture plaque assays directly from the blood of a calf infected with two serotypes of bluetongue virus. The majority (89%) of progeny viruses isolated f...

journal_title：Journal of virology

authors： Stott JL,Oberst RD,Channell MB,Osburn BI

更新日期：1987-09-01 00:00:00

abstract：:Although picornavirus RNA genomes contain a 3'-terminal poly(A) tract that is critical for their replication, the impact of encephalomyocarditis virus (EMCV) infection on the host poly(A)-binding protein (PABP) remains unknown. Here, we establish that EMCV infection stimulates site-specific PABP proteolysis, resulting...

journal_title：Journal of virology

authors： Kobayashi M,Arias C,Garabedian A,Palmenberg AC,Mohr I

更新日期：2012-10-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) is the most common congenitally transmitted pathogen worldwide, impacting an estimated 1 million newborns annually. Congenital HCMV (cCMV) infection is a major global contributor to long-term neurologic deficits, including deafness, microcephaly, and neurodevelopmental delay, as well as to...

journal_title：Journal of virology

authors： Permar SR,Schleiss MR,Plotkin SA

更新日期：2018-03-14 00:00:00

abstract：:The ribonucleic acid (RNA) of murine leukemia virus (MLV) Rauscher strain was observed by the aid of electron microscopy with the use of the protein monolayer technique. RNA was observed directly after release from virus particles or after isolation by sedimentation in sucrose density gradients. Molecules were found i...

journal_title：Journal of virology

authors： Kakefuda T,Bader JP

更新日期：1969-10-01 00:00:00

abstract：:Adenovirus infection and expression of E1A induces both proliferation and apoptosis, the latter of which is blocked by the adenovirus Bcl-2 homologue E1B 19K. The mechanism of apoptosis induction and the role that it plays in productive infection are not known. Unlike apoptosis mediated by death receptors, infection w...

journal_title：Journal of virology

authors： Cuconati A,Degenhardt K,Sundararajan R,Anschel A,White E

更新日期：2002-05-01 00:00:00

abstract：:The Tf1 retrotransposon of Schizosaccharomyces pombe represents a group of eukaryotic long terminal repeat (LTR) retroelements that, based on their sequences, were predicted to use an RNA self-primer for initiating reverse transcription while synthesizing the negative-sense DNA strand. This feature is substantially di...

journal_title：Journal of virology

authors： Hizi A

更新日期：2008-11-01 00:00:00

abstract：:p21((WAF1/SDII/CIP1)) (p21) arrests cell growth by inhibiting cyclin-depend kinases. To explore the potential of using p21 for the gene therapy of cervical cancer, we infected human papillomavirus (HPV)-positive cervical cancer cells (HeLa, SiHa, and Z172) and HPV-negative cervical cancer cells (C33A) with recombinant...

journal_title：Journal of virology

authors： Tsao YP,Huang SJ,Chang JL,Hsieh JT,Pong RC,Chen SL

更新日期：1999-06-01 00:00:00

abstract：:Molluscs, comprising one of the most successful phyla, lack clear evidence of adaptive immunity and yet thrive in the oceans, which are rich in viruses. There are thought to be nearly 120,000 species of Mollusca, most living in marine habitats. Despite the extraordinary abundance of viruses in oceans, molluscs often h...

journal_title：Journal of virology

authors： Dang VT,Benkendorff K,Green T,Speck P

更新日期：2015-08-01 00:00:00

abstract：:Autophagy is now known to be an essential component of host innate and adaptive immunity. Several herpesviruses have developed various strategies to evade this antiviral host defense. Herpes simplex virus 1 (HSV-1) blocks autophagy in fibroblasts and in neurons, and the ICP34.5 protein is important for the resistance ...

journal_title：Journal of virology

authors： Lussignol M,Queval C,Bernet-Camard MF,Cotte-Laffitte J,Beau I,Codogno P,Esclatine A

更新日期：2013-01-01 00:00:00

abstract：:Feline leukemia viruses (FeLVs) belonging to interference subgroup C induce fatal anemia resembling human pure red cell aplasia (PRCA). Subgroup A FeLVs, although closely related genetically to FeLVs of subgroup C, do not induce PRCA. The determinants for PRCA induction by a molecularly cloned prototype subgroup C vir...

journal_title：Journal of virology

authors： Dean GA,Groshek PM,Mullins JI,Hoover EA

更新日期：1992-09-01 00:00:00

abstract：:Historically, coronaviruses were predominantly associated with mild upper respiratory disease in humans. More recently, three novel coronaviruses associated with severe human respiratory disease were found, including (i) the severe acute respiratory syndrome coronavirus, associated with a significant atypical pneumoni...

journal_title：Journal of virology

authors： Donaldson EF,Yount B,Sims AC,Burkett S,Pickles RJ,Baric RS

更新日期：2008-12-01 00:00:00

abstract：:Marek's disease virus DNA appears to be wound around a central structure connecting the two inner poles of the capsid. Based on electron micrographs of Marek's disease virions, a diagram of spatial configuration of virus DNA is presented. This diagram may explain the pleomorphic character of the herpesvirus core obser...

journal_title：Journal of virology

authors： Nazerian K

更新日期：1974-05-01 00:00:00