Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS.

abstract：UNLABELLED:Influenza virus transcription requires functional coupling with cellular transcription for the cap-snatching process. Despite this fact, RNA polymerase II (RNAP II) is degraded during infection in a process triggered by the viral polymerase. Reassortant viruses from the A/PR/8/34 (PR8) strain that induce (hv...

journal_title：Journal of virology

authors： Llompart CM,Nieto A,Rodriguez-Frandsen A

更新日期：2014-03-01 00:00:00

abstract：:A gene encoding the large T antigen of polyomavirus was inserted into the baculovirus Autographa californica nuclear polyhedrosis virus so that gene expression was under the control of the strong, very late polyhedrin gene promoter. Significantly more large T antigen was produced in recombinant virus-infected insect c...

journal_title：Journal of virology

authors： Rice WC,Lorimer HE,Prives C,Miller LK

更新日期：1987-05-01 00:00:00

abstract：UNLABELLED:Cattle have been proposed as the natural reservoir of a novel member of the virus family Orthomyxoviridae, which has been tentatively classified as influenza D virus (IDV). Although isolated from sick animals, it is unclear whether IDV causes any clinical disease in cattle. To address this aspect of Koch's p...

journal_title：Journal of virology

authors： Ferguson L,Olivier AK,Genova S,Epperson WB,Smith DR,Schneider L,Barton K,McCuan K,Webby RJ,Wan XF

更新日期：2016-05-27 00:00:00

abstract：:Efficient T-cell responses against recombinant antigens expressed by vaccinia virus vectors require expression of these antigens in the early phase of the virus replication cycle. The kinetics of recombinant gene expression in poxviruses are largely determined by the promoter chosen. We used the highly attenuated modi...

journal_title：Journal of virology

authors： Baur K,Brinkmann K,Schweneker M,Pätzold J,Meisinger-Henschel C,Hermann J,Steigerwald R,Chaplin P,Suter M,Hausmann J

更新日期：2010-09-01 00:00:00

abstract：:The occurrence of genome segment reassortment between two antigenically related orbiviruses was demonstrated in cattle. Individual virus clones were isolated by cell culture plaque assays directly from the blood of a calf infected with two serotypes of bluetongue virus. The majority (89%) of progeny viruses isolated f...

journal_title：Journal of virology

authors： Stott JL,Oberst RD,Channell MB,Osburn BI

更新日期：1987-09-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is typically acquired asymptomatically in childhood. In contrast, infection later in life often leads to infectious mononucleosis (IM), a febrile illness characterized by anti-EBV IgM antibody positivity, high loads of circulating latently infected B cells, and a marked lymphocytosis caused by...

journal_title：Journal of virology

authors： Abbott RJ,Pachnio A,Pedroza-Pacheco I,Leese AM,Begum J,Long HM,Croom-Carter D,Stacey A,Moss PAH,Hislop AD,Borrow P,Rickinson AB,Bell AI

更新日期：2017-10-13 00:00:00

abstract：:Ribosomes are observed intimately associated with nucleocapsids of vesicular, stomatitis virus, especially those that line structures that are either cytoplasmic vesicles or invaginations of the plasma membrane. ...

journal_title：Journal of virology

authors： Orenstein J,Shelton E,Lazzarini RA

更新日期：1975-08-01 00:00:00

abstract：:The emergence in 1997 and continuance today of a highly lethal H5N1 avian influenza virus (AIV) causing human disease has raised concern about an impending pandemic and the need for a vaccine to prepare for such an occurrence. We previously generated an efficacious vesicular stomatitis virus (VSV)-based AIV vaccine ex...

journal_title：Journal of virology

authors： Schwartz JA,Buonocore L,Suguitan AL Jr,Silaghi A,Kobasa D,Kobinger G,Feldmann H,Subbarao K,Rose JK

更新日期：2010-05-01 00:00:00

abstract：UNLABELLED:The HIV-1 glycoprotein 41 promotes fusion of the viral membrane with that of the target cell. Structural, biochemical, and biophysical studies suggest that its membrane-proximal external region (MPER) may interact with the HIV-1 membrane and induce its disruption and/or deformation during the process. Howeve...

journal_title：Journal of virology

authors： Apellániz B,Rujas E,Carravilla P,Requejo-Isidro J,Huarte N,Domene C,Nieva JL

更新日期：2014-11-01 00:00:00

abstract：UNLABELLED:The genus beta human papillomaviruses (beta HPVs) cause cutaneous lesions and are thought to be involved in the initiation of some nonmelanoma skin cancers (NMSCs), particularly in patients with the genetic disorder epidermodysplasia verruciformis (EV). We have previously reported that at least two of the ge...

journal_title：Journal of virology

authors： White EA,Walther J,Javanbakht H,Howley PM

更新日期：2014-08-01 00:00:00

abstract：:Signal peptidase cleavage at the C-prM junction in the flavivirus structural polyprotein is inefficient in the absence of the cytoplasmic viral protease, which catalyzes cleavage at the COOH terminus of the C protein. The signal peptidase cleavage occurs efficiently in circumstances where the C protein is deleted or i...

journal_title：Journal of virology

authors： Stocks CE,Lobigs M

更新日期：1998-03-01 00:00:00

abstract：:The interaction of the human immunodeficiency virus type 1 (HIV-1) nucleoprotein complex with the cell nuclear import machinery is necessary for viral replication in macrophages and for the establishment of infection in quiescent T lymphocytes. The karyophilic properties of two viral proteins, matrix (MA) and Vpr, are...

journal_title：Journal of virology

authors： Gallay P,Stitt V,Mundy C,Oettinger M,Trono D

更新日期：1996-02-01 00:00:00

abstract：:Historically, coronaviruses were predominantly associated with mild upper respiratory disease in humans. More recently, three novel coronaviruses associated with severe human respiratory disease were found, including (i) the severe acute respiratory syndrome coronavirus, associated with a significant atypical pneumoni...

journal_title：Journal of virology

authors： Donaldson EF,Yount B,Sims AC,Burkett S,Pickles RJ,Baric RS

更新日期：2008-12-01 00:00:00

abstract：:Inoculation of 3-day-old (3D) or 3-week-old (3W) ducklings with duck hepatitis B virus results in chronic or transient infection, respectively. We previously showed that rapid production of neutralizing antibody following inoculation of 3W ducklings prevents virus from spreading in the liver and leads to a transient i...

journal_title：Journal of virology

authors： Zhang YY,Theele DP,Summers J

更新日期：2005-08-01 00:00:00

abstract：:Inhibition of RNA synthesis of the LH strain of type 3 poliovirus at the restrictive temperature occurs concurrently with the breakdown of noncapsid virus-specific peptide 2. This finding, along with other reported data (B.D. Korant, In Proteases and Biological Control, p. 621-644, 1975), suggests that noncapsid virus...

journal_title：Journal of virology

authors： Bowles SA,Tershak DR

更新日期：1978-08-01 00:00:00

abstract：:In December 2016, a low-pathogenic avian influenza (LPAI) A(H7N2) virus was identified to be the causative source of an outbreak in a cat shelter in New York City, which subsequently spread to multiple shelters in the states of New York and Pennsylvania. One person with occupational exposure to infected cats became in...

journal_title：Journal of virology

authors： Belser JA,Pulit-Penaloza JA,Sun X,Brock N,Pappas C,Creager HM,Zeng H,Tumpey TM,Maines TR

更新日期：2017-07-12 00:00:00

abstract：:The molecular mechanisms responsible for random integration and gene targeting by recombinant adeno-associated virus (AAV) vectors are largely unknown, and whether vectors derived from autonomous parvoviruses transduce cells by similar pathways has not been investigated. In this report, we constructed vectors based on...

journal_title：Journal of virology

authors： Hendrie PC,Hirata RK,Russell DW

更新日期：2003-12-01 00:00:00

abstract：:Induction of the resident prophage did not permit restricted phage T1 to replicate freely in P1-lysogenic hosts. A few induced cells did become infectible. ...

journal_title：Journal of virology

authors： Christensen JR,Werner ER

更新日期：1969-04-01 00:00:00

abstract：:Transcription of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) is activated through binding of the viral Tat protein to the trans-activating response (TAR) element at the 5' end of the nascent transcript. Whereas HIV type 1 (HIV-1) TAR folds a simple hairpin structure, the corresponding do...

journal_title：Journal of virology

authors： Centlivre M,Klaver B,Berkhout B,Das AT

更新日期：2008-09-01 00:00:00

abstract：:The extracellular virion form (EV) of vaccinia virus (VACV) is essential for viral pathogenesis and is difficult to neutralize with antibodies. Why this is the case and how the smallpox vaccine overcomes this challenge remain incompletely understood. We previously showed that high concentrations of anti-B5 antibodies ...

journal_title：Journal of virology

authors： Benhnia MR,Maybeno M,Blum D,Aguilar-Sino R,Matho M,Meng X,Head S,Felgner PL,Zajonc DM,Koriazova L,Kato S,Burton DR,Xiang Y,Crowe JE Jr,Peters B,Crotty S

更新日期：2013-02-01 00:00:00

abstract：:Early stages of infection by the mouse polyomavirus have been studied using HeLa cells stably expressing small interfering RNA to protein disulfide isomerase (PDI). Infectibility measured by nuclear T antigen expression was reduced commensurately with the degree of PDI downregulation. Infectibility was restored by tra...

journal_title：Journal of virology

authors： Gilbert J,Ou W,Silver J,Benjamin T

更新日期：2006-11-01 00:00:00

abstract：:Hepatitis C virus (HCV) RNA genome replicates within the ribonucleoprotein (RNP) complex in the modified membranous structures extended from endoplasmic reticulum. A proteomic analysis of HCV RNP complexes revealed the association of oxysterol binding protein (OSBP) as one of the components of these complexes. OSBP in...

journal_title：Journal of virology

authors： Amako Y,Sarkeshik A,Hotta H,Yates J 3rd,Siddiqui A

更新日期：2009-09-01 00:00:00

abstract：:Cholesterol has been implicated in various viral life cycle steps for different enveloped viruses, including viral entry into host cells, cell-cell fusion, and viral budding from infected cells. Enveloped viruses acquire their membranes from their host cells. Though cholesterol has been associated with binding and ent...

journal_title：Journal of virology

authors： Contreras EM,Johnston GP,Buchholz DW,Ortega V,Monreal IA,Zamora JLR,Cheung T,Aguilar HC

更新日期：2021-01-06 00:00:00

abstract：:The vesicular stomatitis virus (VSV) RNA-dependent RNA polymerase consists of two viral proteins; the large (L) protein is the main catalytic subunit, and the phosphoprotein (P) is an essential cofactor for polymerase function. The P protein interacts with the L protein and the N-RNA template, thus connecting the poly...

journal_title：Journal of virology

authors： Mondal A,Victor KG,Pudupakam RS,Lyons CE,Wertz GW

更新日期：2014-02-01 00:00:00

abstract：:TRIM5α is a natural resistance factor that binds retroviral capsid proteins and restricts virus replication. The B30.2/SPRY domain of TRIM5α is polymorphic in rhesus macaques, and some alleles are associated with reduced simian immunodeficiency virus (SIV) SIV(mac251) and SIV(smE543) replication in vivo. We determined...

journal_title：Journal of virology

authors： Fenizia C,Keele BF,Nichols D,Cornara S,Binello N,Vaccari M,Pegu P,Robert-Guroff M,Ma ZM,Miller CJ,Venzon D,Hirsch V,Franchini G

更新日期：2011-12-01 00:00:00

abstract：:A detailed analysis of the expression of the bacterial chloramphenicol acetyltransferase gene controlled by the herpes simplex virus major capsid protein (VP5) promoter showed that this promoter can be functionally separated into an 80-base core region, which has the minimal information required to serve as a pol II p...

journal_title：Journal of virology

authors： Blair ED,Wagner EK

更新日期：1986-11-01 00:00:00

abstract：:Alternative splicing of the human immunodeficiency virus type 1 (HIV-1) genomic mRNA produces more than 40 unique viral mRNA species, of which more than half remain incompletely spliced within an HIV-1-infected cell. Regulation of splicing at HIV-1 3' splice sites (3'ss) requires suboptimal polypyrimidine tracts, and ...

journal_title：Journal of virology

authors： Madsen JM,Stoltzfus CM

更新日期：2005-08-01 00:00:00

abstract：:Infection and transformation of chondrocytes by Rous sarcoma viruses (RSVs) (Schmidt-Ruppin, Prague) stimulated the rate of cell growth. In contrast, several transformation-defective (td) mutants (tdPRA, tdNY105, tdNY106, tdNY107, and tdNY108) retaining various sizes of the src gene did not stimulate cell growth, indi...

journal_title：Journal of virology

authors： Tanaka A,Parker C,Kaji A

更新日期：1980-08-01 00:00:00

abstract：:Type I interferons (IFNs), including alpha IFN (IFN-α) and IFN-β, potently suppress HIV-1 replication by upregulating IFN-stimulated genes (ISGs). The viral capsid protein (CA) partly determines the sensitivity of HIV-1 to IFNs. However, it remains to be determined whether CA-related functions, including utilization o...

journal_title：Journal of virology

authors： Sultana T,Mamede JI,Saito A,Ode H,Nohata K,Cohen R,Nakayama EE,Iwatani Y,Yamashita M,Hope TJ,Shioda T

更新日期：2019-11-13 00:00:00

abstract：UNLABELLED:Kaposi's sarcoma-associated herpesvirus (KSHV) infection is required for the development of several AIDS-related malignancies, including Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL). The high incidence of AIDS-KS has been ascribed to the interaction of KSHV and HIV-1. We have previously shown th...

journal_title：Journal of virology

authors： Yan Q,Shen C,Qin J,Li W,Hu M,Lu H,Qin D,Zhu J,Gao SJ,Lu C

更新日期：2016-09-12 00:00:00