Abstract：
:Present methods of controlling meningococcal cerebrospinal meningitis have failed to contain the disease. This has led to the search for effective vaccines and to the development of methods for assaying the potency of these vaccines, as well as for measuring the immune response of the individual. The feasibility of using the sero-protection test in embryonated eggs for the assay of meningococcal antibody has been investigated. The paper describes detailed investigations of the infectious process established by injecting Neisseria meningitidis by various challenge routes. Embryos, even 10-12 days old, showed high susceptibility to meningococci injected via the yolksac or chorioallantoic vein, and lesser susceptibility when injected via the intra-allantoic and chorioallantoic routes. The deaths of intravenously inoculated embryos coincided with the multiplication of the organisms and ensuing septicaemia. A study of the infection in embryos which had died, or were killed, 18-24 hours after inoculation showed a specific localization of the organisms in the brain.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Ueda K,Diena BB,Greenberg Lsubject
Has Abstractpub_date
1969-01-01 00:00:00pages
235-40issue
2eissn
0042-9686issn
1564-0604journal_volume
40pub_type
杂志文章abstract：:The author describes the design and operation of an automatic molluscicide dispenser for use in flowing water. The equipment, which consists basically of a measuring weir coupled to a float-activated siphon, was designed for simplicity, low cost, construction with commonly available materials, and operation by untrain...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1956-01-01 00:00:00
abstract：:As in an earlier study, the authors have endeavoured to review the world incidence of poliomyelitis on the basis of the available statistical information (official notifications of cases and deaths) and to compare these data with data received from various sources regarding the prevailing viruses.It is certainly not y...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1956-01-01 00:00:00
abstract：:An epidemic of sleeping sickness, which started in 1976 in a focus within the county of Luuka in Central Busoga, has spread to cover the three districts of Busoga and large parts of the neighbouring districts of Tororo and Mukono. Forty-three isolates of the subgenus Trypanozoon from Busoga and Tororo (27 from man, 9 ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Viruses of various biological types are known to cause a wide range of acute respiratory infections, ranging from mild colds and catarrh to severe bronchiolitis and pneumonia. Bacteria also cause respiratory diseases including serious conditions such as otitis media and pneumonia. The whole situation is complex and to...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Options for health financing reform are often portrayed as a choice between general taxation (known as the Beveridge model) and social health insurance (known as the Bismarck model). Ten years of health financing reform in Kyrgyzstan, since the introduction of its compulsory health insurance fund in 1997, provide an e...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.07.049544
更新日期：2009-07-01 00:00:00
abstract：:Aortic and coronary atherosclerosis were studied in two groups, the "high atherosclerosis group" and the "low atherosclerosis group". The latter may be considered as showing basic levels of atherosclerosis in the different communities. The development of lesions in the two groups occurred in parallel, but earlier in t...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:There is widespread agreement that both the configuration and the application of state authority in the health sector should be realigned in the interest of achieving agreed policy objectives. The desired outcome is frequently characterized as a search for good governance serving the public interest. The present paper...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:In developing countries, chronic respiratory diseases represent a challenge to public health because of their frequency, severity, projected trends, and economic impact. Health care planners, for example, are faced with a dramatic increase in tobacco use and must establish priorities for the allocation of limited reso...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Twenty-six patients suffering from methylmercury poisoning were treated by different therapeutic regimes. Seven received penicillamine or N-acetyl-d-L-penicillamine, 10 were treated with dimercaprol sulfonate and 9, who could not be treated, were given a placebo and were used as controls. Penicillamine, N-acetyl-d-L-p...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Representatives of the WHO influenza programme recently proposed a standard method of determining neuraminidase activity and neuraminidase inhibition (NI) antibody titres. Logit transformation of the data obtained with the WHO method for the NI assay permits a more efficient performance of the test and easy calculatio...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：OBJECTIVE:To appraise the process of development and clinical content of national human immunodeficiency virus (HIV) clinical practice guidelines of countries in the eastern Mediterranean and to formulate recommendations for future guideline development and adaptation. METHODS:Twenty-three countries in the World Healt...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.10.083790
更新日期：2011-06-01 00:00:00
abstract：:The usefulness of a recently developed portable haemoglobinometer in primary health care was assessed in a survey of anaemia carried out in an isolated Indian community living in the jungles of northern Peru. This haemoglobinometer requires only one drop of blood to be added to a disposable cuvette without predilution...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:This paper reviews recent experimental evidence in support of inoculation with antirabies serum, the value of which, as a prophylactic measure, is compared with that of vaccine treatment alone. The author concludes that the chief advantages of combined antiserum-vaccine prophylaxis lie in the rapid treatment of cases ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1954-01-01 00:00:00
abstract：:The sensitivity of Plasmodium falciparum strains to chloroquine was tested in one locality in the north-east of the United Republic of Tanzania, where a chloroquine-medicated salt project has been implemented for chemosuppression for many years, and where large amounts of the drug have been available during the last d...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Uruguay is hosting the WHO Global Conference on Noncommunicable Diseases (NCDs) this month, from 18-20 October. Tabaré Vázquez, the President of Uruguay, tells the Bulletin of the World Health Organization about his country's efforts to prevent and fight NCDs and why countries should step up the global response. ...
journal_title：Bulletin of the World Health Organization
pub_type： 新闻
doi：10.2471/BLT.17.031017
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVE:To determine paediatric blood sample volume limits that are consistent with physiological "minimal risk." METHODS:A literature review was performed to search for evidence concerning the adverse effects of blood sampling in children and for guidelines on sampling volume in paediatric research. The search incl...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：10.2471/BLT.10.080010
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:To improve the use and dosage of antibiotics prescribed at Commune Health Stations in Viet Nam, and in so doing find out whether antibiotic dosage can be easily and reliably measured as a drug-use indicator. METHODS:All commune health workers from the 217 commune health stations in Hai Phong Province, Viet N...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Thiotepa and its oxygen analogue tepa, used to chemosterilize males of Culex pipiens fatigans for genetic control purposes, are toxic and mutagenic. An investigation showed that adult mosquitos that had been treated as pupae showed no detectable chemosterilant in their tissue 24 hours after emergence from the pupal st...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：OBJECTIVE:Delivery by a skilled birth attendant (SBA) serves as an indicator of progress towards reducing maternal mortality worldwide -- the fifth Millennium Development Goal. Though WHO tracks the proportion of women delivered by SBAs, we know little about their competence to manage common life-threatening obstetric ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.06.038455
更新日期：2007-10-01 00:00:00
abstract：:The treatment of cholera with bacteriophage has, in the past, been unsuccessful, owing to the fact that the phages prepared by the usual method (multiplication on cholera vibrios in broth) proved incapable of parasitizing cholera vibrios in vivo. In this paper, the author presents the results of therapeutic and prophy...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1963-01-01 00:00:00
abstract：:A study was made on the effect of undernutrition on the immunological responses of mice to TAB and BCG vaccines. The mice were fed a diet comprising chapati and germinated grams; one group was fed ad libitum while another was given half the quantity consumed by the first group. The undernourished mice showed a poor im...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:The COVID-19 pandemic has drawn attention to the international agreement governing responses to public health emergencies, with some experts calling for its revision. Lynn Eaton and Gary Humphreys report. ...
journal_title：Bulletin of the World Health Organization
pub_type： 新闻
doi：10.2471/BLT.20.020620
更新日期：2020-06-01 00:00:00
abstract：:Studies were made on the host-feeding patterns and behaviour of 4 Culex species in China (Province of Taiwan) to further assess their importance as vectors of Japanese encephalitis. A relatively unbiased, non-attractant technique (vacuum sweep-net) was used for collecting mosquitos resting outdoors on rural premises; ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1973-01-01 00:00:00
abstract：:A survey of the sandfly population of Iran was conducted in the interests of providing further knowledge of the biology of these vectors of leishmaniasis, sandfly fever and kalaazar. The search for specimens was carried out in the Tabriz, Sarab, Caspian Sea, Teheran and Kazerun areas, both inside buildings and in natu...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1961-01-01 00:00:00
abstract：:Access to contraceptives in Africa has not increased at the same pace as elsewhere in the world. Some African nations are investing in family planning services to reduce fertility rates, improve economic development and their population's health. Tatum Anderson reports. ...
journal_title：Bulletin of the World Health Organization
pub_type： 新闻
doi：10.2471/BLT.17.020917
更新日期：2017-09-01 00:00:00
abstract：:Subjects with sickle cell trait have been known to offer resistance to induced Plasmodium falciparum infection. The resistance to malarial infection in other haemoglobinopathic disorders is not clearly known. Investigations were undertaken to test for resistance to malaria in Hb E thalassaemia disease. Compared to con...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1964-01-01 00:00:00
abstract：OBJECTIVE:To determine trends in mortality from respiratory disease in several areas of Latin America between 1998 and 2009. METHODS:The numbers of deaths attributed to respiratory disease between 1998 and 2009 were extracted from mortality data from Argentina, southern Brazil, Chile, Costa Rica, Ecuador, Mexico and P...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.12.116871
更新日期：2013-07-01 00:00:00
abstract：:The paper presents clinical observations on 1 233 persons with smallpox who were admitted to the Infectious Diseases Hospital, Calcutta, in 1973. The disease was of the modified type in 53 patients (4.3%), the ordinary type in 717 (58.2%), the flat type in 249 (20.2%), and the haemorrhagic type in 214 (17.3%). The fat...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:Reported are the results of a study to investigate the immunogenicity of oral poliovirus vaccine (OPV) when administered in mass campaigns compared with that following routine immunization programmes. For this purpose, paired sera were collected from a cohort of children before and after a mass vaccination with OPV in...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:In 39 randomly selected villages and towns in Tumkur District, South India, approximately 2000 persons, tuberculosis cases and matched controls, were interviewed in order to determine how many had symptoms suggestive of tuberculosis. Approximately 70% of the bacteriologically confirmed cases and over half the radiolog...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1963-01-01 00:00:00
