Source of the nonlinear dependence of bacteriophage SP82 transfection on deoxyribonucleic acid concentration.

abstract：:Recombinant vaccinia viruses expressing C-terminally truncated E's that ranged in length from 9 to 99% of the N-terminal sequence were constructed. The overall antigenicity of the E products was analyzed by radioimmunoprecipitation, using dengue virus hyperimmune mouse ascitic fluid (HMAF) or an anti-E peptide serum. ...

journal_title：Journal of virology

authors： Men RH,Bray M,Lai CJ

更新日期：1991-03-01 00:00:00

abstract：:Sequences present at the genomic termini of herpesviruses become linked during lytic-phase replication and provide the substrate for cleavage and packaging of unit length viral genomes. We have previously shown that homologs of the consensus herpesvirus cleavage-packaging signals, pac1 and pac2, are located at the lef...

journal_title：Journal of virology

authors： Deng H,Dewhurst S

更新日期：1998-01-01 00:00:00

abstract：:Most current diagnostic tests for transmissible spongiform encephalopathies (TSE) rely on the presence of proteinase K (PK)-resistant PrP(Sc) (PrP-res) in postmortem tissues as an indication of TSE disease. However, a number of studies have highlighted a discrepancy between TSE infectivity and PrP-res levels in both n...

journal_title：Journal of virology

authors： Dobie K,Barron R

更新日期：2013-05-01 00:00:00

abstract：:The internal hydrophobic sequence within the flaviviral capsid protein (protein C) plays an important role in the assembly of infectious virions. Here, this sequence was analyzed in a West Nile virus lineage I isolate (crow V76/1). An infectious cDNA clone was constructed and used to introduce deletions into the inter...

journal_title：Journal of virology

authors： Schlick P,Taucher C,Schittl B,Tran JL,Kofler RM,Schueler W,von Gabain A,Meinke A,Mandl CW

更新日期：2009-06-01 00:00:00

abstract：:All human influenza pandemics have originated from avian influenza viruses. Although multiple changes are needed for an avian virus to be able to transmit between humans, binding to human-type receptors is essential. Several research groups have reported mutations in H5N1 viruses that exhibit specificity for human-typ...

journal_title：Journal of virology

authors： Peng W,Bouwman KM,McBride R,Grant OC,Woods RJ,Verheije MH,Paulson JC,de Vries RP

更新日期：2018-04-27 00:00:00

abstract：UNLABELLED:The potency and breadth of the recently isolated neutralizing human monoclonal antibodies to HIV-1 have stimulated interest in their use to prevent or to treat HIV-1 infection. Due to the antigenically diverse nature of the HIV-1 envelope (Env), no single antibody is highly active against all viral strains. ...

journal_title：Journal of virology

authors： Asokan M,Rudicell RS,Louder M,McKee K,O'Dell S,Stewart-Jones G,Wang K,Xu L,Chen X,Choe M,Chuang G,Georgiev IS,Joyce MG,Kirys T,Ko S,Pegu A,Shi W,Todd JP,Yang Z,Bailer RT,Rao S,Kwong PD,Nabel GJ,Mascola JR

更新日期：2015-12-01 00:00:00

abstract：:Skin fibroblast cultures were established from eight individuals. These cell cultures, together with WI-38 cells, were examined for susceptibility to transformation by SV40 virus. Four transformation-susceptible cell lines (TS), established from patients with Down's syndrome, were found to be three to four times more ...

journal_title：Journal of virology

authors： Potter CW,Potter AM,Oxford JS

更新日期：1970-03-01 00:00:00

abstract：:One common attribute of herpesviruses is the ability to establish latent, life-long infections. The role of virus-virus interaction in viral reactivation between or among herpesviruses has not been studied. Preliminary experiments in our laboratory had indicated that infection of Epstein-Barr virus (EBV) genome-positi...

journal_title：Journal of virology

authors： Flamand L,Stefanescu I,Ablashi DV,Menezes J

更新日期：1993-11-01 00:00:00

abstract：:Nearly 50 years ago, the discovery of interferon prompted the notion that host cells innately respond to viral invasion. Since that time, technological advances have allowed this response to be extensively characterized and dissected in vitro. However, these advances have only recently been applied to highly complex, ...

journal_title：Journal of virology

authors： Hartman ZC,Kiang A,Everett RS,Serra D,Yang XY,Clay TM,Amalfitano A

更新日期：2007-02-01 00:00:00

abstract：:Spatial variation in the epidemiological patterns of successive waves of pandemic influenza virus in humans has been documented throughout the 20th century but never understood at a molecular level. However, the unprecedented intensity of sampling and whole-genome sequencing of the H1N1/09 pandemic virus now makes suc...

journal_title：Journal of virology

authors： Nelson MI,Tan Y,Ghedin E,Wentworth DE,St George K,Edelman L,Beck ET,Fan J,Lam TT,Kumar S,Spiro DJ,Simonsen L,Viboud C,Holmes EC,Henrickson KJ,Musser JM

更新日期：2011-01-01 00:00:00

abstract：UNLABELLED:The novel H7N9 avian influenza virus (AIV) was demonstrated to cause severe human respiratory infections in China. Here, we examined poultry specimens from live bird markets linked to human H7N9 infection in Hangzhou, China. Metagenomic sequencing revealed mixed subtypes (H5, H7, H9, N1, N2, and N9). Subsequ...

journal_title：Journal of virology

authors： Yu Y,Wang X,Jin T,Wang H,Si W,Yang H,Wu J,Yan Y,Liu G,Sang X,Wu X,Gao Y,Xia X,Yu X,Pan J,Gao GF,Zhou J

更新日期：2015-09-01 00:00:00

abstract：:Human papillomaviruses (HPVs) infect squamous epithelium and establish their genomes as episomes in proliferating basal cells. As infected cells differentiate, the viral DNA is amplified to high copy number and infectious virus is produced. Viral production has not yet been observed in vitro due to the inability of st...

journal_title：Journal of virology

authors： Bedell MA,Hudson JB,Golub TR,Turyk ME,Hosken M,Wilbanks GD,Laimins LA

更新日期：1991-05-01 00:00:00

abstract：:Revertants of Kirsten sarcoma virus transformed nonproducer BALB/3T3 cells (KA31 cells) were isolated after exposing the transformed cells to 5-fluorodeoxyuridine at high cell density, or when suspended in methylcellulose. Revertants were also isolated by treating KA31 cells with the lectin, concanavalin A, which is m...

journal_title：Journal of virology

authors： Ozanne B,Vogel A

更新日期：1974-08-01 00:00:00

abstract：:The chimeric murine oncornavirus FrCas(E) causes a rapidly progressive paralytic disease associated with spongiform neurodegeneration throughout the neuroaxis. Neurovirulence is determined by the sequence of the viral envelope gene and by the capacity of the virus to infect microglia. The neurocytopathic effect of thi...

journal_title：Journal of virology

authors： Askovic S,Favara C,McAtee FJ,Portis JL

更新日期：2001-03-01 00:00:00

abstract：:Rotavirus NSP5 is a nonstructural protein that localizes in cytoplasmic viroplasms of infected cells. NSP5 interacts with NSP2 and undergoes a complex posttranslational hyperphosphorylation, generating species with reduced polyacrylamide gel electrophoresis mobility. This process has been suggested to be due in part t...

journal_title：Journal of virology

authors： Eichwald C,Vascotto F,Fabbretti E,Burrone OR

更新日期：2002-04-01 00:00:00

abstract：UNLABELLED:Pneumonia virus of mice (PVM) is a natural rodent pathogen that replicates in bronchial epithelial cells and reproduces many clinical and pathological features of the more severe forms of disease associated with human respiratory syncytial virus. In order to track virus-target cell interactions during acute ...

journal_title：Journal of virology

authors： Dyer KD,Drummond RA,Rice TA,Percopo CM,Brenner TA,Barisas DA,Karpe KA,Moore ML,Rosenberg HF

更新日期：2015-11-04 00:00:00

abstract：:Mutations critical for the central nervous system (CNS) attenuation of the Sabin vaccine strains of poliovirus (PV) are located within the viral internal ribosome entry site (IRES). We examined the interaction of the IRESs of PV type 3 (PV3) and Sabin type 3 (Sabin3) with polypyrimidine tract-binding protein (PTB) and...

journal_title：Journal of virology

authors： Guest S,Pilipenko E,Sharma K,Chumakov K,Roos RP

更新日期：2004-10-01 00:00:00

abstract：:Expression of the region of the feline calicivirus (FCV) ORF1 encoded by nucleotides 3233 to 4054 in an in vitro rabbit reticulocyte system resulted in synthesis of an active proteinase that specifically processes the viral nonstructural polyprotein. Site-directed mutagenesis of the cysteine (Cys1193) residue in the p...

journal_title：Journal of virology

authors： Sosnovtseva SA,Sosnovtsev SV,Green KY

更新日期：1999-08-01 00:00:00

abstract：:Bats are the second largest group of mammals on earth and act as reservoirs of many emerging viruses. In this study, a novel bat adenovirus (AdV) (BtAdV-TJM) was isolated from bat fecal samples by using a bat primary kidney cell line. Infection studies indicated that most animal and human cell lines are susceptible to...

journal_title：Journal of virology

authors： Li Y,Ge X,Zhang H,Zhou P,Zhu Y,Zhang Y,Yuan J,Wang LF,Shi Z

更新日期：2010-04-01 00:00:00

abstract：:We have developed a complementation assay, using transiently transfected COS cells, to facilitate a molecular analysis of the herpes simplex virus type 1 glycoprotein gH. When infected by a gH-null syncytial virus, COS cells expressing wild-type gH generate infectious progeny virions and form a syncytium with neighbor...

journal_title：Journal of virology

authors： Wilson DW,Davis-Poynter N,Minson AC

更新日期：1994-11-01 00:00:00

abstract：:The genome of a human papillomavirus (HPV) found in a patient with Bowen's disease of the skin was molecularly cloned. Blot hybridization experiments, performed under stringent conditions, revealed no cross-hybridization between this HPV DNA and the other known HPV DNAs, showing that this HPV represents a new type, te...

journal_title：Journal of virology

authors： Kawashima M,Jablonska S,Favre M,Obalek S,Croissant O,Orth G

更新日期：1986-02-01 00:00:00

abstract：:Formation of a six-helix bundle comprised of three C-terminal heptad repeat regions in antiparallel orientation in the grooves of an N-terminal coiled-coil is critical for promotion of membrane fusion by paramyxovirus fusion (F) proteins. We have examined the effect of mutations in four residues of the N-terminal hept...

journal_title：Journal of virology

authors： West DS,Sheehan MS,Segeleon PK,Dutch RE

更新日期：2005-02-01 00:00:00

abstract：:We cloned and analyzed the integrated human papillomavirus type 16 (HPV-16) genomes that are present in the human cervical carcinoma cell lines SiHa and CaSki. The single HPV-16 genome in the SiHa line was cloned as a 10-kilobase (kb) HindIII fragment. Integration of the HPV-16 genome occurred at bases 3132 and 3384 w...

journal_title：Journal of virology

authors： Baker CC,Phelps WC,Lindgren V,Braun MJ,Gonda MA,Howley PM

更新日期：1987-04-01 00:00:00

abstract：:SE21Q1b, a Rous sarcoma virus mutant which packages cellular rather than viral RNA, is competent for infection of quail cells and can transmit defective transforming retrovirus genes. Stably transformed recipient clones have been obtained by using this mutant. ...

journal_title：Journal of virology

authors： Linial M

更新日期：1981-04-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) plays a significant role in the development of Kaposi's sarcoma, primary effusion lymphoma, and some forms of multicentric Castleman's disease. The KSHV open reading frame K9 encodes the viral interferon (IFN) factor 1 (vIRF1), which downregulates IFN- and IRF-mediated tr...

journal_title：Journal of virology

authors： Seo T,Lee D,Shim YS,Angell JE,Chidambaram NV,Kalvakolanu DV,Choe J

更新日期：2002-09-01 00:00:00

abstract：:Cytotoxic T-lymphocyte (CTL) responses are crucial for the control of immunodeficiency virus replication. Possible involvement of a dominant single epitope-specific CTL in control of viral replication has recently been indicated in preclinical AIDS vaccine trials, but it has remained unclear if multiple epitope-specif...

journal_title：Journal of virology

authors： Kawada M,Igarashi H,Takeda A,Tsukamoto T,Yamamoto H,Dohki S,Takiguchi M,Matano T

更新日期：2006-02-01 00:00:00

abstract：:The capsid (CA) domain of the Moloney murine leukemia virus (Mo-MuLV) Gag protein has a unique carboxy terminus with a highly charged arginine-rich sequence. Mutant viruses harboring arginine-to-alanine mutations affecting this region of CA displayed significant defects in virion release, and the few viral particles p...

journal_title：Journal of virology

authors： Wang MQ,Goff SP

更新日期：2003-03-01 00:00:00

abstract：:Fanconi anemia (FA) patients have an increased risk for squamous cell carcinomas (SCCs) at sites of predilection for infection with high-risk human papillomavirus (HPV) types, including the oral cavity and the anogenital tract. We show here that activation of the FA pathway is a frequent event in cervical SCCs. We fou...

journal_title：Journal of virology

authors： Spardy N,Duensing A,Charles D,Haines N,Nakahara T,Lambert PF,Duensing S

更新日期：2007-12-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is associated with about 6 to 16% of gastric carcinoma cases worldwide. Expression of the EBV microRNAs (miRNAs) was observed in B cells and nasopharyngeal carcinoma cells infected with EBV. However, it is not clear if the EBV miRNAs are expressed in EBV-associated gastric carcinomas (EBVaGCs)...

journal_title：Journal of virology

authors： Kim DN,Chae HS,Oh ST,Kang JH,Park CH,Park WS,Takada K,Lee JM,Lee WK,Lee SK

更新日期：2007-01-01 00:00:00

abstract：UNLABELLED:In a genome-wide small interfering RNA (siRNA) screen, we recently identified the interferon (IFN)-inducible protein 35 (IFI35; also known as IFP35) as a factor required for vesicular stomatitis virus (VSV) infection. Studies reported here were conducted to further understand the role and requirement of IFI3...

journal_title：Journal of virology

authors： Das A,Dinh PX,Panda D,Pattnaik AK

更新日期：2014-03-01 00:00:00