Spiking neural circuits with dendritic stimulus processors : encoding, decoding, and identification in reproducing kernel Hilbert spaces.

abstract：:We address how spatial frequency selectivity arises in Macaque primary visual cortex (V1) by simulating V1 with a large-scale network model consisting of O(10(4)) excitatory and inhibitory integrate-and-fire neurons with realistic synaptic conductances. The new model introduces variability of the widths of subregions ...

journal_title：Journal of computational neuroscience

authors： Zhu W,Shelley M,Shapley R

更新日期：2009-04-01 00:00:00

abstract：:Prominent models of spike trains assume only one source of variability - stochastic (Poisson) spiking - when stimuli and behavior are fixed. However, spike trains may also reflect variability due to internal processes such as planning. For example, we can plan a movement at one point in time and execute it at some arb...

journal_title：Journal of computational neuroscience

authors： Lawlor PN,Perich MG,Miller LE,Kording KP

更新日期：2018-12-01 00:00:00

abstract：:Information maximization has long been suggested as the underlying coding strategy of the primary visual cortex (V1). Grouping image sequences into blocks has been shown by others to improve agreement between experiments and theory. We have studied the effect of temporal convolution on the formation of spatiotemporal ...

journal_title：Journal of computational neuroscience

authors： Szatmáry B,Lorincz A

更新日期：2001-11-01 00:00:00

abstract：:We present a new method to characterize multi-input and output neuronal systems using information theory. To obtain a lower bound of transinformation we take three steps: (1) Estimation of the deterministic response to isolate components carrying stimulus information. The deviation of the original response from the de...

journal_title：Journal of computational neuroscience

authors： Eger M,Eckhorn R

更新日期：2002-05-01 00:00:00

abstract：:Models of electrical activity in excitable cells involve nonlinear interactions between many ionic currents. Changing parameters in these models can produce a variety of activity patterns with sometimes unexpected effects. Further more, introducing new currents will have different effects depending on the initial para...

journal_title：Journal of computational neuroscience

authors： Fletcher P,Bertram R,Tabak J

更新日期：2016-06-01 00:00:00

abstract：:Information from the vestibular, sensorimotor, or visual systems can affect the firing of grid cells recorded in entorhinal cortex of rats. Optic flow provides information about the rat's linear and rotational velocity and, thus, could influence the firing pattern of grid cells. To investigate this possible link, we m...

journal_title：Journal of computational neuroscience

authors： Raudies F,Mingolla E,Hasselmo ME

更新日期：2012-12-01 00:00:00

abstract：:We investigate the use of extracellular action potential (EAP) recordings for biophysically faithful compartmental models. We ask whether constraining a model to fit the EAP is superior to matching the intracellular action potential (IAP). In agreement with previous studies, we find that the IAP method under-constrain...

journal_title：Journal of computational neuroscience

authors： Gold C,Henze DA,Koch C

更新日期：2007-08-01 00:00:00

abstract：:Hebbian plasticity means that if the firing of two neurons is correlated, then their connection is strengthened. Conversely, uncorrelated firing causes a decrease in synaptic strength. Spike-timing-dependent plasticity (STDP) represents one instantiation of Hebbian plasticity. Under STDP, synaptic changes depend on th...

journal_title：Journal of computational neuroscience

authors： Houben AM,Keil MS

更新日期：2020-02-01 00:00:00

abstract：:Encoding brain regions and their connections as a network of nodes and edges captures many of the possible paths along which information can be transmitted as humans process and perform complex behaviors. Because cognitive processes involve large, distributed networks of brain areas, principled examinations of multi-n...

journal_title：Journal of computational neuroscience

authors： Sizemore AE,Giusti C,Kahn A,Vettel JM,Betzel RF,Bassett DS

更新日期：2018-02-01 00:00:00

abstract：:The kinematics of the hand and fingers were studied during various keystrokes in typing. These movements were defined by 17 degrees of freedom of motion, and methods were developed to identify simplifying strategies in the execution of the task. Most of the analysis was restricted to the 11 degrees of freedom of the f...

journal_title：Journal of computational neuroscience

authors： Soechting JF,Flanders M

更新日期：1997-01-01 00:00:00

abstract：:Waves have long been thought to be a fundamental mechanism for communicating information within a medium and are widely observed in biological systems. However, a quantitative analysis of biological waves is confounded by the variability and complexity of the response. This paper proposes a robust technique for extrac...

journal_title：Journal of computational neuroscience

authors： Robbins KA,Senseman DM

更新日期：2004-05-01 00:00:00

abstract：:An analytical model is proposed that can predict the shape of the poststimulus time histogram (PSTH) response to a current pulse of a neuron subjected to uncorrelated background input. The model is based on an explicit description of noise in the form of an escape rate and corresponding hazard function. Two forms of t...

journal_title：Journal of computational neuroscience

authors： Herrmann A,Gerstner W

更新日期：2001-09-01 00:00:00

abstract：:The original version of this article unfortunately has some typographical errors in equations (5), (6), (7), (8), and (12). ...

journal_title：Journal of computational neuroscience

authors： Devecioğlu İ,Güçlü B

更新日期：2020-08-01 00:00:00

abstract：:With the advancement in computer technology, it has become possible to fit complex models to neuronal data. In this work, we test how two methods can estimate parameters of simple neuron models (passive soma) to more complex ones (neuron with one dendritic cylinder and two active conductances). The first method uses c...

journal_title：Journal of computational neuroscience

authors： Tabak J,Murphey CR,Moore LE

更新日期：2000-11-01 00:00:00

abstract：:We explore the effects of stochastic sodium (Na) channel activation on the variability and dynamics of spiking and bursting in a model neuron. The complete model segregates Hodgin-Huxley-type currents into two compartments, and undergoes applied current-dependent bifurcations between regimes of periodic bursting, chao...

journal_title：Journal of computational neuroscience

authors： Rowat PF,Elson RC

更新日期：2004-03-01 00:00:00

abstract：:A population of uncoupled neurons can often be brought close to synchrony by a single strong inhibitory input pulse affecting all neurons equally. This mechanism is thought to underlie some brain rhythms, in particular gamma frequency (30-80 Hz) oscillations in the hippocampus and neocortex. Here we show that synchron...

journal_title：Journal of computational neuroscience

authors： Börgers C,Krupa M,Gielen S

更新日期：2010-06-01 00:00:00

abstract：:The paper presents a hierarchical series of computational models for myelinated axonal compartments. Three classes of models are considered, either with distributed parameters (2.5D EQS-ElectroQuasi Static, 1D TL-Transmission Lines) or with lumped parameters (0D). They are systematically analyzed with both analytical ...

journal_title：Journal of computational neuroscience

authors： Ioan D,Bărbulescu R,Silveira LM,Ciuprina G

更新日期：2019-12-01 00:00:00

abstract：:This modeling study examines the possible functional roles of two hyperpolarization-activated conductances in lateral superior olive (LSO) principal neurons. Inputs of these LSO neurons are transformed into an output, which provides a firing-rate code for a certain interaural sound intensity difference (IID) range. Re...

journal_title：Journal of computational neuroscience

authors： Szalisznyó K

更新日期：2006-04-01 00:00:00

abstract：:Lyapunov exponents are a basic and powerful tool to characterise the long-term behaviour of dynamical systems. The computation of Lyapunov exponents for continuous time dynamical systems is straightforward whenever they are ruled by vector fields that are sufficiently smooth to admit a variational model. Hybrid neuron...

journal_title：Journal of computational neuroscience

authors： Bizzarri F,Brambilla A,Gajani GS

更新日期：2013-10-01 00:00:00

abstract：:We have previously formulated an abstract dynamical system for networks of spiking neurons and derived a formal result that identifies the criterion for its dynamics, without inputs, to be "sensitive to initial conditions". Since formal results are applicable only to the extent to which their assumptions are valid, we...

journal_title：Journal of computational neuroscience

authors： Banerjee A

更新日期：2006-06-01 00:00:00

abstract：:Retinal ganglion cells (RGCs) display differences in their morphology and intrinsic electrophysiology. The goal of this study is to characterize the ionic currents that explain the behavior of ON and OFF RGCs and to explore if all morphological types of RGCs exhibit the phenomena described in electrophysiological data...

journal_title：Journal of computational neuroscience

authors： Maturana MI,Kameneva T,Burkitt AN,Meffin H,Grayden DB

更新日期：2014-04-01 00:00:00

abstract：:When two-frame apparent motion stimuli are presented with an appropriate inter-stimulus interval (ISI), motion is perceived in the direction opposite to the actual image shift. Herein, we measured a simple eye movement, ocular following responses (OFRs), in macaque monkeys to examine the ISI reversal effect on oculomo...

journal_title：Journal of computational neuroscience

authors： Takemura A,Matsumoto J,Hashimoto R,Kawano K,Miura K

更新日期：2020-07-17 00:00:00

abstract：:We present a model for the use of open loop optogenetic control to inhibit epileptiform activity in a meso scale model of the human cortex. The meso scale cortical model first developed by Liley et al. (2001) is extended to two dimensions and the nature of the seizure waves is studied. We adapt to the meso scale a 4 s...

journal_title：Journal of computational neuroscience

authors： Selvaraj P,Sleigh JW,Freeman WJ,Kirsch HE,Szeri AJ

更新日期：2014-06-01 00:00:00

abstract：:We use a modeling approach to examine ideas derived from physiological network analyses, pertaining to the switch of a motor control network between two opposite control modes. We studied the femur-tibia joint control system of the insect leg, and its switch between resistance reflex in posture control and "active rea...

journal_title：Journal of computational neuroscience

authors： Stein W,Straub O,Ausborn J,Mader W,Wolf H

更新日期：2008-12-01 00:00:00

abstract：:During slow-wave sleep, brain electrical activity is dominated by the slow (< 1 Hz) electroencephalogram (EEG) oscillations characterized by the periodic transitions between active (or Up) and silent (or Down) states in the membrane voltage of the cortical and thalamic neurons. Sleep slow oscillation is believed to pl...

journal_title：Journal of computational neuroscience

authors： Komarov M,Krishnan G,Chauvette S,Rulkov N,Timofeev I,Bazhenov M

更新日期：2018-02-01 00:00:00

abstract：:The effect of a non-symmetric waveform on nerve conduction block induced by high-frequency biphasic stimulation is investigated using a lumped circuit model of the unmyelinated axon based on Hodgkin-Huxley equations. The simulation results reveal that the block threshold monotonically increases with the stimulation fr...

journal_title：Journal of computational neuroscience

authors： Zhao S,Yang G,Wang J,Roppolo JR,de Groat WC,Tai C

更新日期：2014-10-01 00:00:00

abstract：:Purkinje cells aligned on the medio-lateral axis share a large proportion of their approximately 175,000 parallel fiber inputs. This arrangement has led to the hypothesis that movement timing is coded in the cerebellum by beams of synchronously active parallel fibers. In computer simulations I show that such synchrono...

journal_title：Journal of computational neuroscience

authors： Jaeger D

更新日期：2003-05-01 00:00:00

abstract：:In this paper, we systematically investigate both the synfire propagation and firing rate propagation in feedforward neuronal network coupled in an all-to-all fashion. In contrast to most earlier work, where only reliable synaptic connections are considered, we mainly examine the effects of unreliable synapses on both...

journal_title：Journal of computational neuroscience

authors： Guo D,Li C

更新日期：2011-06-01 00:00:00

abstract：:Calmodulin (CaM) is a major Ca(2+) binding protein involved in two opposing processes of synaptic plasticity of CA1 pyramidal neurons: long-term potentiation (LTP) and depression (LTD). The N- and C-terminal lobes of CaM bind to its target separately but cooperatively and introduce complex dynamics that cannot be well...

journal_title：Journal of computational neuroscience

authors： Byrne MJ,Putkey JA,Waxham MN,Kubota Y

更新日期：2009-12-01 00:00:00

abstract：:Epilepsy is one of the most common neurological disorders and is characterized by recurrent seizures. We use theoretical neuroscience tools to study brain dynamics during seizures. We derive and simulate a computational model of a network of hippocampal neuronal populations. Each population within the network is based...

journal_title：Journal of computational neuroscience

authors： Kameneva T,Ying T,Guo B,Freestone DR

更新日期：2017-04-01 00:00:00