Abstract:
:The original version of this article unfortunately has some typographical errors in equations (5), (6), (7), (8), and (12).
journal_name
J Comput Neuroscijournal_title
Journal of computational neuroscienceauthors
Devecioğlu İ,Güçlü Bdoi
10.1007/s10827-020-00759-0subject
Has Abstractpub_date
2020-08-01 00:00:00pages
355issue
3eissn
0929-5313issn
1573-6873pii
10.1007/s10827-020-00759-0journal_volume
48pub_type
已发布勘误abstract::A population of uncoupled neurons can often be brought close to synchrony by a single strong inhibitory input pulse affecting all neurons equally. This mechanism is thought to underlie some brain rhythms, in particular gamma frequency (30-80 Hz) oscillations in the hippocampus and neocortex. Here we show that synchron...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-010-0233-8
更新日期:2010-06-01 00:00:00
abstract::The response of leaky integrate-and-fire neurons is analyzed for periodic inputs whose phases vary with their spatial location. The model gives the relationship between the spatial summation distance and the degree of phase locking of the output spikes (i.e., locking to the periodic stochastic inputs, measured by the ...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1023/a:1014994113776
更新日期:2002-01-01 00:00:00
abstract::Inhibitory networks are now recognized as being the controllers of several brain rhythms. However, experimental work with inhibitory cells is technically difficult not only because of their smaller percentage of the neuronal population, but also because of their diverse properties. As such, inhibitory network models w...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-005-0331-1
更新日期:2005-06-01 00:00:00
abstract::Activation of calcium/calmodulin-dependent protein kinase II (CaMKII) by calmodulin following calcium entry into the cell is important for long-term potentiation (LTP). Here a model of calmodulin binding and trapping by CaMKII in a dendritic spine was used to estimate levels and durations of CaMKII activation followin...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1023/a:1008969032563
更新日期:2000-01-01 00:00:00
abstract::Information theoretical approaches to sensory processing in electric fish have focused on the encoding of amplitude modulations in a single sensory pathway in the South American gymnotiforms. To assess the generality of these studies, we investigated the encoding of amplitude and phase modulations in the distantly rel...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-007-0062-6
更新日期:2008-08-01 00:00:00
abstract::The timing of transmitter release from nerve endings is considered nowadays as one of the factors determining the plasticity and efficacy of synaptic transmission. In the neuromuscular junction, the moments of release of individual acetylcholine quanta are related to the synaptic delays of uniquantal endplate currents...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-015-0567-3
更新日期:2015-10-01 00:00:00
abstract::We consider whole-cell voltage-clamp data of isolated currents characterized by the Hodgkin-Huxley paradigm. We examine the errors associated with the typical parameter estimation method for these data and show them to be unsatisfactorally large especially if the time constants of activation and inactivation are not s...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1023/a:1008880518515
更新日期:1999-03-01 00:00:00
abstract::Stellate cells in the cat antero-ventral cochlear nucleus (AVCN) maintain a robust rate-place representation of vowel spectra over a wide range of stimulus levels. This rate-place representation resembles that of low threshold, high spontaneous rate (SR) auditory nerve fibers (ANFs) at low stimulus levels, and that of...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章,评审
doi:10.1007/BF00961733
更新日期:1994-08-01 00:00:00
abstract::Many mechanisms of neural processing rely critically upon the synaptic connectivity between neurons. As our ability to simultaneously record from large populations of neurons expands, the ability to infer network connectivity from this data has become a major goal of computational neuroscience. To address this issue, ...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-013-0443-y
更新日期:2013-08-01 00:00:00
abstract::Confirming that synaptic loss is directly related to cognitive deficit in Alzheimer's disease (AD) has been the focus of many studies. Compensation mechanisms counteract synaptic loss and prevent the catastrophic amnesia induced by synaptic loss via maintaining the activity levels of neural circuits. Here we investiga...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-013-0462-8
更新日期:2014-02-01 00:00:00
abstract::Many animals produce pulse-like signals during acoustic communication. These signals exhibit structure on two time scales: they consist of trains of pulses that are often broadcast in packets-so called chirps. Temporal parameters of the pulse and of the chirp are decisive for female preference. Despite these signals b...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-013-0441-0
更新日期:2013-08-01 00:00:00
abstract::Purkinje cells aligned on the medio-lateral axis share a large proportion of their approximately 175,000 parallel fiber inputs. This arrangement has led to the hypothesis that movement timing is coded in the cerebellum by beams of synchronously active parallel fibers. In computer simulations I show that such synchrono...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1023/a:1023217111784
更新日期:2003-05-01 00:00:00
abstract::Mathematical neuronal models are normally expressed using differential equations. The Parker-Sochacki method is a new technique for the numerical integration of differential equations applicable to many neuronal models. Using this method, the solution order can be adapted according to the local conditions at each time...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-008-0131-5
更新日期:2009-08-01 00:00:00
abstract::With the advancement in computer technology, it has become possible to fit complex models to neuronal data. In this work, we test how two methods can estimate parameters of simple neuron models (passive soma) to more complex ones (neuron with one dendritic cylinder and two active conductances). The first method uses c...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1023/a:1026531603628
更新日期:2000-11-01 00:00:00
abstract::The kinematics of the hand and fingers were studied during various keystrokes in typing. These movements were defined by 17 degrees of freedom of motion, and methods were developed to identify simplifying strategies in the execution of the task. Most of the analysis was restricted to the 11 degrees of freedom of the f...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1023/a:1008812426305
更新日期:1997-01-01 00:00:00
abstract::Following a flashed stimulus, I show that a simple neurophysiological mechanism in the primary visual system can generate orientation selectivity based on the first incoming spikes. A biological model of the lateral geniculate nucleus generates an asynchronous wave of spikes, with the most strongly activated neurons f...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1023/a:1027420012134
更新日期:2003-11-01 00:00:00
abstract::The existence of electrical communication among pyramidal cells (PCs) in the adult cortex has been debated by neuroscientists for several decades. Gap junctions (GJs) among cortical interneurons have been well documented experimentally and their functional roles have been proposed by both computational neuroscientists...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-020-00762-5
更新日期:2020-11-01 00:00:00
abstract::During neural development sensory stimulation induces long-term changes in the receptive field of the neurons that encode the stimuli. The Bienenstock-Cooper-Munro (BCM) model was introduced to model and analyze this process computationally, and it remains one of the major models of unsupervised plasticity to this day...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-019-00715-7
更新日期:2019-04-01 00:00:00
abstract::The background activity of a cortical neural network is modeled by a homogeneous integrate-and-fire network with unreliable inhibitory synapses. For the case of fast synapses, numerical and analytical calculations show that the network relaxes into a stationary state of high attention. The majority of the neurons has ...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-007-0049-3
更新日期:2008-02-01 00:00:00
abstract::The effect of a non-symmetric waveform on nerve conduction block induced by high-frequency biphasic stimulation is investigated using a lumped circuit model of the unmyelinated axon based on Hodgkin-Huxley equations. The simulation results reveal that the block threshold monotonically increases with the stimulation fr...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-014-0510-z
更新日期:2014-10-01 00:00:00
abstract::Hebbian plasticity means that if the firing of two neurons is correlated, then their connection is strengthened. Conversely, uncorrelated firing causes a decrease in synaptic strength. Spike-timing-dependent plasticity (STDP) represents one instantiation of Hebbian plasticity. Under STDP, synaptic changes depend on th...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-019-00737-1
更新日期:2020-02-01 00:00:00
abstract::The primary goal of this study was to construct a simulation model of a biofeedback brain-computer interface (BCI) system to analyze the effect of biofeedback training on BCI users. A mathematical model of a man-machine visual-biofeedback BCI system was constructed to simulate a subject using a BCI system to control c...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-009-0148-4
更新日期:2009-12-01 00:00:00
abstract::Information transfer may not be limited only to synapses. Therefore, the processes and dynamics of biological neuron-astrocyte coupling and intercellular interaction within this domain are worth investigating. Existing models of tripartite synapse consider an astrocyte as a point process. Here, we extended the tripart...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-019-00734-4
更新日期:2020-02-01 00:00:00
abstract::Sensory neurons code information about stimuli in their sequence of action potentials (spikes). Intuitively, the spikes should represent stimuli with high fidelity. However, generating and propagating spikes is a metabolically expensive process. It is therefore likely that neural codes have been selected to balance en...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-016-0592-x
更新日期:2016-04-01 00:00:00
abstract::Simultaneous recordings of spike trains from multiple single neurons are becoming commonplace. Understanding the interaction patterns among these spike trains remains a key research area. A question of interest is the evaluation of information flow between neurons through the analysis of whether one spike train exerts...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-008-0126-2
更新日期:2009-08-01 00:00:00
abstract::We have presented a new generation mechanism of slow spiking or repetitive discharges with extraordinarily long inter-spike intervals using the modified Hodgkin-Huxley equations (Doi and Kumagai, 2001). This generation process of slow firing is completely different from that of the well-known potassium A-current in th...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-005-2895-1
更新日期:2005-12-01 00:00:00
abstract::We have previously formulated an abstract dynamical system for networks of spiking neurons and derived a formal result that identifies the criterion for its dynamics, without inputs, to be "sensitive to initial conditions". Since formal results are applicable only to the extent to which their assumptions are valid, we...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-006-7188-9
更新日期:2006-06-01 00:00:00
abstract::We investigated the effect of mean firing on the information rate of a spiking motion-sensitive neuron in the fly (H1-cell). In the control condition, the cell was stimulated repeatedly by identical zero-symmetrical white-noise motion. The mean firing rate was manipulated by adding a constant velocity offset either in...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1023/a:1011225232120
更新日期:2001-03-01 00:00:00
abstract::Computational modeling of dendritic morphology is a powerful tool for quantitatively describing complex geometrical relationships, uncovering principles of dendritic development, and synthesizing virtual neurons to systematically investigate cellular biophysics and network dynamics. A feature common to many morphologi...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-005-1850-5
更新日期:2005-10-01 00:00:00
abstract::Lyapunov exponents are a basic and powerful tool to characterise the long-term behaviour of dynamical systems. The computation of Lyapunov exponents for continuous time dynamical systems is straightforward whenever they are ruled by vector fields that are sufficiently smooth to admit a variational model. Hybrid neuron...
journal_title:Journal of computational neuroscience
pub_type: 杂志文章
doi:10.1007/s10827-013-0448-6
更新日期:2013-10-01 00:00:00