abstract：:The existence of electrical communication among pyramidal cells (PCs) in the adult cortex has been debated by neuroscientists for several decades. Gap junctions (GJs) among cortical interneurons have been well documented experimentally and their functional roles have been proposed by both computational neuroscientists...

journal_title：Journal of computational neuroscience

authors： Crodelle J,Zhou D,Kovačič G,Cai D

更新日期：2020-11-01 00:00:00

abstract：:Networks of spiking neurons can have persistently firing stable bump attractors to represent continuous spaces (like temperature). This can be done with a topology with local excitatory synapses and local surround inhibitory synapses. Activating large ranges in the attractor can lead to multiple bumps, that show repel...

journal_title：Journal of computational neuroscience

authors： Huyck CR,Vergani AA

更新日期：2020-08-01 00:00:00

abstract：:The original version of this article unfortunately has some typographical errors in equations (5), (6), (7), (8), and (12). ...

journal_title：Journal of computational neuroscience

authors： Devecioğlu İ,Güçlü B

更新日期：2020-08-01 00:00:00

abstract：:When two-frame apparent motion stimuli are presented with an appropriate inter-stimulus interval (ISI), motion is perceived in the direction opposite to the actual image shift. Herein, we measured a simple eye movement, ocular following responses (OFRs), in macaque monkeys to examine the ISI reversal effect on oculomo...

journal_title：Journal of computational neuroscience

authors： Takemura A,Matsumoto J,Hashimoto R,Kawano K,Miura K

更新日期：2020-07-17 00:00:00

abstract：:Transcranial Direct brain stimulation (tDCS) is commonly used in order to modulate cortical networks activity during physiological processes through the application of weak electrical fields with scalp electrodes. Cathodal stimulation has been shown to decrease brain excitability in the context of epilepsy, with varia...

journal_title：Journal of computational neuroscience

authors： Denoyer Y,Merlet I,Wendling F,Benquet P

更新日期：2020-05-01 00:00:00

abstract：:In this paper, we investigate the dynamics of a neuron-glia cell system and the underlying mechanism for the occurrence of seizures. For our mathematical and numerical investigation of the cell model we will use bifurcation analysis and some computational methods. It turns out that an increase of the potassium concent...

journal_title：Journal of computational neuroscience

authors： Erhardt AH,Mardal KA,Schreiner JE

更新日期：2020-05-01 00:00:00

abstract：:Hebbian plasticity means that if the firing of two neurons is correlated, then their connection is strengthened. Conversely, uncorrelated firing causes a decrease in synaptic strength. Spike-timing-dependent plasticity (STDP) represents one instantiation of Hebbian plasticity. Under STDP, synaptic changes depend on th...

journal_title：Journal of computational neuroscience

authors： Houben AM,Keil MS

更新日期：2020-02-01 00:00:00

abstract：:Information transfer may not be limited only to synapses. Therefore, the processes and dynamics of biological neuron-astrocyte coupling and intercellular interaction within this domain are worth investigating. Existing models of tripartite synapse consider an astrocyte as a point process. Here, we extended the tripart...

journal_title：Journal of computational neuroscience

authors： Lorenzo J,Vuillaume R,Binczak S,Jacquir S

更新日期：2020-02-01 00:00:00

abstract：:The paper presents a hierarchical series of computational models for myelinated axonal compartments. Three classes of models are considered, either with distributed parameters (2.5D EQS-ElectroQuasi Static, 1D TL-Transmission Lines) or with lumped parameters (0D). They are systematically analyzed with both analytical ...

journal_title：Journal of computational neuroscience

authors： Ioan D,Bărbulescu R,Silveira LM,Ciuprina G

更新日期：2019-12-01 00:00:00

abstract：:A neuron's firing correlates are defined as the features of the external world to which its activity is correlated. In many parts of the brain, neurons have quite simple such firing correlates. A striking example are grid cells in the rodent medial entorhinal cortex: their activity correlates with the animal's positio...

journal_title：Journal of computational neuroscience

authors： Rosay S,Weber S,Mulas M

更新日期：2019-08-01 00:00:00

abstract：:During neural development sensory stimulation induces long-term changes in the receptive field of the neurons that encode the stimuli. The Bienenstock-Cooper-Munro (BCM) model was introduced to model and analyze this process computationally, and it remains one of the major models of unsupervised plasticity to this day...

journal_title：Journal of computational neuroscience

authors： Froc M,van Rossum MCW

更新日期：2019-04-01 00:00:00

abstract：:Several neuron types have been shown to exhibit (subthreshold) membrane potential resonance (MPR), defined as the occurrence of a peak in their voltage amplitude response to oscillatory input currents at a preferred (resonant) frequency. MPR has been investigated both experimentally and theoretically. However, whether...

journal_title：Journal of computational neuroscience

authors： Bel A,Rotstein HG

更新日期：2019-04-01 00:00:00

abstract：:Prominent models of spike trains assume only one source of variability - stochastic (Poisson) spiking - when stimuli and behavior are fixed. However, spike trains may also reflect variability due to internal processes such as planning. For example, we can plan a movement at one point in time and execute it at some arb...

journal_title：Journal of computational neuroscience

authors： Lawlor PN,Perich MG,Miller LE,Kording KP

更新日期：2018-12-01 00:00:00

abstract：:Replicability and reproducibility of computational models has been somewhat understudied by "the replication movement." In this paper, we draw on methodological studies into the replicability of psychological experiments and on the mechanistic account of explanation to analyze the functions of model replications and m...

journal_title：Journal of computational neuroscience

authors： Miłkowski M,Hensel WM,Hohol M

更新日期：2018-12-01 00:00:00

abstract：:A critical component of any statistical modeling procedure is the ability to assess the goodness-of-fit between a model and observed data. For spike train models of individual neurons, many goodness-of-fit measures rely on the time-rescaling theorem and assess model quality using rescaled spike times. Recently, there ...

journal_title：Journal of computational neuroscience

authors： Tao L,Weber KE,Arai K,Eden UT

更新日期：2018-10-01 00:00:00

abstract：:Encoding brain regions and their connections as a network of nodes and edges captures many of the possible paths along which information can be transmitted as humans process and perform complex behaviors. Because cognitive processes involve large, distributed networks of brain areas, principled examinations of multi-n...

journal_title：Journal of computational neuroscience

authors： Sizemore AE,Giusti C,Kahn A,Vettel JM,Betzel RF,Bassett DS

更新日期：2018-02-01 00:00:00

abstract：:Voltage-sensitive dye imaging (VSDi) has revealed fundamental properties of neocortical processing at macroscopic scales. Since for each pixel VSDi signals report the average membrane potential over hundreds of neurons, it seems natural to use a mean-field formalism to model such signals. Here, we present a mean-field...

journal_title：Journal of computational neuroscience

authors： Zerlaut Y,Chemla S,Chavane F,Destexhe A

更新日期：2018-02-01 00:00:00

abstract：:During slow-wave sleep, brain electrical activity is dominated by the slow (< 1 Hz) electroencephalogram (EEG) oscillations characterized by the periodic transitions between active (or Up) and silent (or Down) states in the membrane voltage of the cortical and thalamic neurons. Sleep slow oscillation is believed to pl...

journal_title：Journal of computational neuroscience

authors： Komarov M,Krishnan G,Chauvette S,Rulkov N,Timofeev I,Bazhenov M

更新日期：2018-02-01 00:00:00

abstract：:The pathophysiology of auditory hallucination, a common symptom of schizophrenia, has yet been understood, but during auditory hallucination, primary auditory cortex (A1) shows paradoxical responses. When auditory stimuli are absent, A1 becomes hyperactive, while A1 responses to auditory stimuli are reduced. Such acti...

journal_title：Journal of computational neuroscience

authors： Lee JH

更新日期：2017-12-01 00:00:00

abstract：:A neuron receives input from other neurons via electrical pulses, so-called spikes. The pulse-like nature of the input is frequently neglected in analytical studies; instead, the input is usually approximated to be Gaussian. Recent experimental studies have shown, however, that an assumption underlying this approximat...

journal_title：Journal of computational neuroscience

authors： Droste F,Lindner B

更新日期：2017-08-01 00:00:00

abstract：:Epilepsy is one of the most common neurological disorders and is characterized by recurrent seizures. We use theoretical neuroscience tools to study brain dynamics during seizures. We derive and simulate a computational model of a network of hippocampal neuronal populations. Each population within the network is based...

journal_title：Journal of computational neuroscience

authors： Kameneva T,Ying T,Guo B,Freestone DR

更新日期：2017-04-01 00:00:00

abstract：:Neuron modeling may be said to have originated with the Hodgkin and Huxley action potential model in 1952 and Rall's models of integrative activity of dendrites in 1964. Over the ensuing decades, these approaches have led to a massive development of increasingly accurate and complex data-based models of neurons and ne...

journal_title：Journal of computational neuroscience

authors： McDougal RA,Morse TM,Carnevale T,Marenco L,Wang R,Migliore M,Miller PL,Shepherd GM,Hines ML

更新日期：2017-02-01 00:00:00

abstract：:One of the most common examples of audiovisual speech integration is the McGurk effect. As an example, an auditory syllable /ba/ recorded over incongruent lip movements that produce "ga" typically causes listeners to hear "da". This report hypothesizes reasons why certain clinical and listeners who are hard of hearing...

journal_title：Journal of computational neuroscience

authors： Altieri N,Yang CT

更新日期：2016-10-01 00:00:00

abstract：:Models of electrical activity in excitable cells involve nonlinear interactions between many ionic currents. Changing parameters in these models can produce a variety of activity patterns with sometimes unexpected effects. Further more, introducing new currents will have different effects depending on the initial para...

journal_title：Journal of computational neuroscience

authors： Fletcher P,Bertram R,Tabak J

更新日期：2016-06-01 00:00:00

abstract：:Sensory neurons code information about stimuli in their sequence of action potentials (spikes). Intuitively, the spikes should represent stimuli with high fidelity. However, generating and propagating spikes is a metabolically expensive process. It is therefore likely that neural codes have been selected to balance en...

journal_title：Journal of computational neuroscience

authors： Johnson EC,Jones DL,Ratnam R

更新日期：2016-04-01 00:00:00

abstract：:We introduce a method for computing probabilities for spontaneous activity and propagation failure of the action potential in spatially extended, conductance-based neuronal models subject to noise, based on statistical properties of the membrane potential. We compare different estimators with respect to the quality of...

journal_title：Journal of computational neuroscience

authors： Sauer M,Stannat W

更新日期：2016-02-01 00:00:00

abstract：:The timing of transmitter release from nerve endings is considered nowadays as one of the factors determining the plasticity and efficacy of synaptic transmission. In the neuromuscular junction, the moments of release of individual acetylcholine quanta are related to the synaptic delays of uniquantal endplate currents...

journal_title：Journal of computational neuroscience

authors： Saveliev A,Khuzakhmetova V,Samigullin D,Skorinkin A,Kovyazina I,Nikolsky E,Bukharaeva E

更新日期：2015-10-01 00:00:00

abstract：:It is widely believed that the theta rhythm in the hippocampus is caused by the rhythmic input from the medial septum-diagonal band of Broca (MSDB). The main MSDB output is formed by GABAergic projection neurons which are divided into two subpopulations and fire at different phases of the hippocampal theta rhythm. The...

journal_title：Journal of computational neuroscience

authors： Mysin IE,Kitchigina VF,Kazanovich Y

更新日期：2015-08-01 00:00:00

abstract：:This work presents a probabilistic method for inferring the parameter ranges in a biologically relevant mathematical model of the cortex most likely to be producing seizures observed in an electrocorticogram (ECoG) signal from a human subject. Additionally, this method produces a probabilistic pathway of the temporal ...

journal_title：Journal of computational neuroscience

authors： Dadok VM,Kirsch HE,Sleigh JW,Lopour BA,Szeri AJ

更新日期：2015-06-01 00:00:00

abstract：:We present a multi-input multi-output neural circuit architecture for nonlinear processing and encoding of stimuli in the spike domain. In this architecture a bank of dendritic stimulus processors implements nonlinear transformations of multiple temporal or spatio-temporal signals such as spike trains or auditory and ...

journal_title：Journal of computational neuroscience

authors： Lazar AA,Slutskiy YB

更新日期：2015-02-01 00:00:00

abstract：:Neural mass models are successful in modeling brain rhythms as observed in macroscopic measurements such as the electroencephalogram (EEG). While the synaptic current is explicitly modeled in current models, the single cell electrophysiology is not taken into account. To allow for investigations of the effects of chan...

journal_title：Journal of computational neuroscience

authors： Zandt BJ,Visser S,van Putten MJ,Ten Haken B

更新日期：2014-12-01 00:00:00

abstract：:The primary sensory feature represented within the rodent barrel cortex is the velocity with which a whisker has been deflected. Whisker deflection velocity is encoded within the thalamus via population synchrony (higher deflection velocities entail greater synchrony among the corresponding thalamic population). Thala...

journal_title：Journal of computational neuroscience

authors： Liu R,Patel M,Joshi B

更新日期：2014-12-01 00:00:00

abstract：:Implementation of double cable models to simulate the behavior of myelinated peripheral nerve fibers requires defining a segmentation of the internode between successive nodes of Ranvier. The number of internodal segments is a model parameter that is not well agreed on, with values in the literature ranging from 1 to ...

journal_title：Journal of computational neuroscience

authors： Dekker DM,Briaire JJ,Frijns JH

更新日期：2014-10-01 00:00:00

abstract：:The effect of a non-symmetric waveform on nerve conduction block induced by high-frequency biphasic stimulation is investigated using a lumped circuit model of the unmyelinated axon based on Hodgkin-Huxley equations. The simulation results reveal that the block threshold monotonically increases with the stimulation fr...

journal_title：Journal of computational neuroscience

authors： Zhao S,Yang G,Wang J,Roppolo JR,de Groat WC,Tai C

更新日期：2014-10-01 00:00:00

abstract：:Many neuron types exhibit preferred frequency responses in their voltage amplitude (resonance) or phase shift to subthreshold oscillatory currents, but the effect of biophysical parameters on these properties is not well understood. We propose a general framework to analyze the role of different ionic currents and the...

journal_title：Journal of computational neuroscience

authors： Rotstein HG,Nadim F

更新日期：2014-08-01 00:00:00

abstract：:We present a model for the use of open loop optogenetic control to inhibit epileptiform activity in a meso scale model of the human cortex. The meso scale cortical model first developed by Liley et al. (2001) is extended to two dimensions and the nature of the seizure waves is studied. We adapt to the meso scale a 4 s...

journal_title：Journal of computational neuroscience

authors： Selvaraj P,Sleigh JW,Freeman WJ,Kirsch HE,Szeri AJ

更新日期：2014-06-01 00:00:00

abstract：:Retinal ganglion cells (RGCs) display differences in their morphology and intrinsic electrophysiology. The goal of this study is to characterize the ionic currents that explain the behavior of ON and OFF RGCs and to explore if all morphological types of RGCs exhibit the phenomena described in electrophysiological data...

journal_title：Journal of computational neuroscience

authors： Maturana MI,Kameneva T,Burkitt AN,Meffin H,Grayden DB

更新日期：2014-04-01 00:00:00

abstract：:Confirming that synaptic loss is directly related to cognitive deficit in Alzheimer's disease (AD) has been the focus of many studies. Compensation mechanisms counteract synaptic loss and prevent the catastrophic amnesia induced by synaptic loss via maintaining the activity levels of neural circuits. Here we investiga...

journal_title：Journal of computational neuroscience

authors： Abuhassan K,Coyle D,Belatreche A,Maguire L

更新日期：2014-02-01 00:00:00

abstract：:Firing-rate models provide a practical tool for studying signal processing in the early visual system, permitting more thorough mathematical analysis than spike-based models. We show here that essential response properties of relay cells in the lateral geniculate nucleus (LGN) can be captured by surprisingly simple fi...

journal_title：Journal of computational neuroscience

authors： Heiberg T,Kriener B,Tetzlaff T,Casti A,Einevoll GT,Plesser HE

更新日期：2013-12-01 00:00:00

abstract：:Lyapunov exponents are a basic and powerful tool to characterise the long-term behaviour of dynamical systems. The computation of Lyapunov exponents for continuous time dynamical systems is straightforward whenever they are ruled by vector fields that are sufficiently smooth to admit a variational model. Hybrid neuron...

journal_title：Journal of computational neuroscience

authors： Bizzarri F,Brambilla A,Gajani GS

更新日期：2013-10-01 00:00:00