Role of hyperpolarization-activated conductances in the lateral superior olive: a modeling study.

abstract：:In inactive stick insects, sensory information from the femoral chordotonal organ (fCO) about position and movement of the femur-tibia joint is transferred via local nonspiking interneurons onto extensor and flexor tibiae motoneurons. Information is processed by the interaction of antagonistic parallel pathways at two...

journal_title：Journal of computational neuroscience

authors： Sauer AE,Driesang RB,Büschges A,Bässler U

更新日期：1996-09-01 00:00:00

abstract：:A neuron's firing correlates are defined as the features of the external world to which its activity is correlated. In many parts of the brain, neurons have quite simple such firing correlates. A striking example are grid cells in the rodent medial entorhinal cortex: their activity correlates with the animal's positio...

journal_title：Journal of computational neuroscience

authors： Rosay S,Weber S,Mulas M

更新日期：2019-08-01 00:00:00

abstract：:We introduce a method for computing probabilities for spontaneous activity and propagation failure of the action potential in spatially extended, conductance-based neuronal models subject to noise, based on statistical properties of the membrane potential. We compare different estimators with respect to the quality of...

journal_title：Journal of computational neuroscience

authors： Sauer M,Stannat W

更新日期：2016-02-01 00:00:00

abstract：:In this paper, we extend our framework for constructing low-dimensional dynamical system models of large-scale neuronal networks of mammalian primary visual cortex. Our dimensional reduction procedure consists of performing a suitable linear change of variables and then systematically truncating the new set of equatio...

journal_title：Journal of computational neuroscience

authors： Tao L,Praissman J,Sornborger AT

更新日期：2012-04-01 00:00:00

abstract：:Information transfer may not be limited only to synapses. Therefore, the processes and dynamics of biological neuron-astrocyte coupling and intercellular interaction within this domain are worth investigating. Existing models of tripartite synapse consider an astrocyte as a point process. Here, we extended the tripart...

journal_title：Journal of computational neuroscience

authors： Lorenzo J,Vuillaume R,Binczak S,Jacquir S

更新日期：2020-02-01 00:00:00

abstract：:Many mechanisms of neural processing rely critically upon the synaptic connectivity between neurons. As our ability to simultaneously record from large populations of neurons expands, the ability to infer network connectivity from this data has become a major goal of computational neuroscience. To address this issue, ...

journal_title：Journal of computational neuroscience

authors： Kobayashi R,Kitano K

更新日期：2013-08-01 00:00:00

abstract：:Networks of spiking neurons can have persistently firing stable bump attractors to represent continuous spaces (like temperature). This can be done with a topology with local excitatory synapses and local surround inhibitory synapses. Activating large ranges in the attractor can lead to multiple bumps, that show repel...

journal_title：Journal of computational neuroscience

authors： Huyck CR,Vergani AA

更新日期：2020-08-01 00:00:00

abstract：:Neuron modeling may be said to have originated with the Hodgkin and Huxley action potential model in 1952 and Rall's models of integrative activity of dendrites in 1964. Over the ensuing decades, these approaches have led to a massive development of increasingly accurate and complex data-based models of neurons and ne...

journal_title：Journal of computational neuroscience

authors： McDougal RA,Morse TM,Carnevale T,Marenco L,Wang R,Migliore M,Miller PL,Shepherd GM,Hines ML

更新日期：2017-02-01 00:00:00

abstract：:The voltage-gated currents in the fly lobula plate tangential cells were examined using the switched electrode voltage clamp technique. In CH cells, two currents were identified (Figs. 1, 2): a slow calcium inward current and a delayed rectifying, noninactivating potassium outward current. HS and VS cells appear to po...

journal_title：Journal of computational neuroscience

authors： Haag J,Theunissen F,Borst A

更新日期：1997-11-01 00:00:00

abstract：:Information from the vestibular, sensorimotor, or visual systems can affect the firing of grid cells recorded in entorhinal cortex of rats. Optic flow provides information about the rat's linear and rotational velocity and, thus, could influence the firing pattern of grid cells. To investigate this possible link, we m...

journal_title：Journal of computational neuroscience

authors： Raudies F,Mingolla E,Hasselmo ME

更新日期：2012-12-01 00:00:00

abstract：:In this paper, we systematically investigate both the synfire propagation and firing rate propagation in feedforward neuronal network coupled in an all-to-all fashion. In contrast to most earlier work, where only reliable synaptic connections are considered, we mainly examine the effects of unreliable synapses on both...

journal_title：Journal of computational neuroscience

authors： Guo D,Li C

更新日期：2011-06-01 00:00:00

abstract：:The existence of electrical communication among pyramidal cells (PCs) in the adult cortex has been debated by neuroscientists for several decades. Gap junctions (GJs) among cortical interneurons have been well documented experimentally and their functional roles have been proposed by both computational neuroscientists...

journal_title：Journal of computational neuroscience

authors： Crodelle J,Zhou D,Kovačič G,Cai D

更新日期：2020-11-01 00:00:00

abstract：:We use a modeling approach to examine ideas derived from physiological network analyses, pertaining to the switch of a motor control network between two opposite control modes. We studied the femur-tibia joint control system of the insect leg, and its switch between resistance reflex in posture control and "active rea...

journal_title：Journal of computational neuroscience

authors： Stein W,Straub O,Ausborn J,Mader W,Wolf H

更新日期：2008-12-01 00:00:00

abstract：:The effect of a non-symmetric waveform on nerve conduction block induced by high-frequency biphasic stimulation is investigated using a lumped circuit model of the unmyelinated axon based on Hodgkin-Huxley equations. The simulation results reveal that the block threshold monotonically increases with the stimulation fr...

journal_title：Journal of computational neuroscience

authors： Zhao S,Yang G,Wang J,Roppolo JR,de Groat WC,Tai C

更新日期：2014-10-01 00:00:00

abstract：:Purkinje cells aligned on the medio-lateral axis share a large proportion of their approximately 175,000 parallel fiber inputs. This arrangement has led to the hypothesis that movement timing is coded in the cerebellum by beams of synchronously active parallel fibers. In computer simulations I show that such synchrono...

journal_title：Journal of computational neuroscience

authors： Jaeger D

更新日期：2003-05-01 00:00:00

abstract：:The active dendritic conductances shape the input-output properties of many principal neurons in different brain regions, and the various ways in which they regulate neuronal excitability need to be investigated to better understand their functional consequences. Using a realistic model of a hippocampal CA1 pyramidal ...

journal_title：Journal of computational neuroscience

authors： Migliore M,Messineo L,Ferrante M

更新日期：2004-01-01 00:00:00

abstract：:Encoding brain regions and their connections as a network of nodes and edges captures many of the possible paths along which information can be transmitted as humans process and perform complex behaviors. Because cognitive processes involve large, distributed networks of brain areas, principled examinations of multi-n...

journal_title：Journal of computational neuroscience

authors： Sizemore AE,Giusti C,Kahn A,Vettel JM,Betzel RF,Bassett DS

更新日期：2018-02-01 00:00:00

abstract：:Nonlinear dynamics provides a complementary framework to control theory for the quantitative analysis of the oculomotor control system. This paper presents a number of findings relating to the aetiology and mechanics of the pathological ocular oscillation jerk congenital nystagmus (jerk CN). A range of time series ana...

journal_title：Journal of computational neuroscience

authors： Akman OE,Broomhead DS,Clement RA,Abadi RV

更新日期：2006-10-01 00:00:00

abstract：:Mathematical neuronal models are normally expressed using differential equations. The Parker-Sochacki method is a new technique for the numerical integration of differential equations applicable to many neuronal models. Using this method, the solution order can be adapted according to the local conditions at each time...

journal_title：Journal of computational neuroscience

authors： Stewart RD,Bair W

更新日期：2009-08-01 00:00:00

abstract：:Replicability and reproducibility of computational models has been somewhat understudied by "the replication movement." In this paper, we draw on methodological studies into the replicability of psychological experiments and on the mechanistic account of explanation to analyze the functions of model replications and m...

journal_title：Journal of computational neuroscience

authors： Miłkowski M,Hensel WM,Hohol M

更新日期：2018-12-01 00:00:00

abstract：:Wider dissemination and testing of computational models are crucial to the field of computational neuroscience. Databases are being developed to meet this need. ModelDB is a web-accessible database for convenient entry, retrieval, and running of published models on different platforms. This article provides a guide to...

journal_title：Journal of computational neuroscience

authors： Hines ML,Morse T,Migliore M,Carnevale NT,Shepherd GM

更新日期：2004-07-01 00:00:00

abstract：:This paper presents a synergistic parametric and non-parametric modeling study of short-term plasticity (STP) in the Schaffer collateral to hippocampal CA1 pyramidal neuron (SC) synapse. Parametric models in the form of sets of differential and algebraic equations have been proposed on the basis of the current underst...

journal_title：Journal of computational neuroscience

authors： Song D,Wang Z,Marmarelis VZ,Berger TW

更新日期：2009-02-01 00:00:00

abstract：:Firing-rate models provide a practical tool for studying signal processing in the early visual system, permitting more thorough mathematical analysis than spike-based models. We show here that essential response properties of relay cells in the lateral geniculate nucleus (LGN) can be captured by surprisingly simple fi...

journal_title：Journal of computational neuroscience

authors： Heiberg T,Kriener B,Tetzlaff T,Casti A,Einevoll GT,Plesser HE

更新日期：2013-12-01 00:00:00

abstract：:The calcium calmodulin dependent kinase (CaMKII) is important for long-term potentiation at dendritic spines. Photo-activatable GFP (PaGFP) - CaMKII fusions were used to map CaMKII movements between and within spines in dissociated hippocampal neurons. Photo-activated PaGFP (GFP*) generated in the shaft spread uniform...

journal_title：Journal of computational neuroscience

authors： Khan S,Reese TS,Rajpoot N,Shabbir A

更新日期：2012-08-01 00:00:00

abstract：:Many neuronal systems exhibit slow random alternations and sudden switches in activity states. Models with noisy relaxation dynamics (oscillatory, excitable or bistable) account for these temporal, slow wave, patterns and the fluctuations within states. The noise-induced transitions in a relaxation dynamics are analog...

journal_title：Journal of computational neuroscience

authors： Lim S,Rinzel J

更新日期：2010-02-01 00:00:00

abstract：:Retinal ganglion cells (RGCs) display differences in their morphology and intrinsic electrophysiology. The goal of this study is to characterize the ionic currents that explain the behavior of ON and OFF RGCs and to explore if all morphological types of RGCs exhibit the phenomena described in electrophysiological data...

journal_title：Journal of computational neuroscience

authors： Maturana MI,Kameneva T,Burkitt AN,Meffin H,Grayden DB

更新日期：2014-04-01 00:00:00

abstract：:Can one develop an abstract description of the dynamics of pattern generators that provides quantitative insight into their operation? We explored this question by examining the dynamics of a model central pattern generator that was created using an evolutionary algorithm. We propose an abstract description based on t...

journal_title：Journal of computational neuroscience

authors： Chiel HJ,Beer RD,Gallagher JC

更新日期：1999-09-01 00:00:00

abstract：:Motoneuron responses were elicited by global visual motion and stepwise displacements of an illuminated stripe. Stimulus protocols were identical to those used in previous behavioral studies of compensatory eyestalk reflexes. The firing rates and directional selectivity of the motoneuron responses were measured with r...

journal_title：Journal of computational neuroscience

authors： Miller CS,Johnson DH,Schroeter JP,Myint L,Glantz RM

更新日期：2003-09-01 00:00:00

abstract：:A population of uncoupled neurons can often be brought close to synchrony by a single strong inhibitory input pulse affecting all neurons equally. This mechanism is thought to underlie some brain rhythms, in particular gamma frequency (30-80 Hz) oscillations in the hippocampus and neocortex. Here we show that synchron...

journal_title：Journal of computational neuroscience

authors： Börgers C,Krupa M,Gielen S

更新日期：2010-06-01 00:00:00

abstract：:Lyapunov exponents are a basic and powerful tool to characterise the long-term behaviour of dynamical systems. The computation of Lyapunov exponents for continuous time dynamical systems is straightforward whenever they are ruled by vector fields that are sufficiently smooth to admit a variational model. Hybrid neuron...

journal_title：Journal of computational neuroscience

authors： Bizzarri F,Brambilla A,Gajani GS

更新日期：2013-10-01 00:00:00