No parallel fiber volleys in the cerebellar cortex: evidence from cross-correlation analysis between Purkinje cells in a computer model and in recordings from anesthetized rats.

abstract：:Nonlinear dynamics provides a complementary framework to control theory for the quantitative analysis of the oculomotor control system. This paper presents a number of findings relating to the aetiology and mechanics of the pathological ocular oscillation jerk congenital nystagmus (jerk CN). A range of time series ana...

journal_title：Journal of computational neuroscience

authors： Akman OE,Broomhead DS,Clement RA,Abadi RV

更新日期：2006-10-01 00:00:00

abstract：:We propose a new retina simulation software, called Virtual Retina, which transforms a video into spike trains. Our goal is twofold: Allow large scale simulations (up to 100,000 neurons) in reasonable processing times and keep a strong biological plausibility, taking into account implementation constraints. The underl...

journal_title：Journal of computational neuroscience

authors： Wohrer A,Kornprobst P

更新日期：2009-04-01 00:00:00

abstract：:The temporal durations between events often exert a strong influence over behavior. The details of this influence have been extensively characterized in behavioral experiments in different animal species. A remarkable feature of the data collected in these experiments is that they are often time-scale invariant. This ...

journal_title：Journal of computational neuroscience

authors： Almeida R,Ledberg A

更新日期：2010-02-01 00:00:00

abstract：:Can one develop an abstract description of the dynamics of pattern generators that provides quantitative insight into their operation? We explored this question by examining the dynamics of a model central pattern generator that was created using an evolutionary algorithm. We propose an abstract description based on t...

journal_title：Journal of computational neuroscience

authors： Chiel HJ,Beer RD,Gallagher JC

更新日期：1999-09-01 00:00:00

abstract：:Encoding brain regions and their connections as a network of nodes and edges captures many of the possible paths along which information can be transmitted as humans process and perform complex behaviors. Because cognitive processes involve large, distributed networks of brain areas, principled examinations of multi-n...

journal_title：Journal of computational neuroscience

authors： Sizemore AE,Giusti C,Kahn A,Vettel JM,Betzel RF,Bassett DS

更新日期：2018-02-01 00:00:00

abstract：:During slow-wave sleep, brain electrical activity is dominated by the slow (< 1 Hz) electroencephalogram (EEG) oscillations characterized by the periodic transitions between active (or Up) and silent (or Down) states in the membrane voltage of the cortical and thalamic neurons. Sleep slow oscillation is believed to pl...

journal_title：Journal of computational neuroscience

authors： Komarov M,Krishnan G,Chauvette S,Rulkov N,Timofeev I,Bazhenov M

更新日期：2018-02-01 00:00:00

abstract：:Voltage-sensitive dye imaging (VSDi) has revealed fundamental properties of neocortical processing at macroscopic scales. Since for each pixel VSDi signals report the average membrane potential over hundreds of neurons, it seems natural to use a mean-field formalism to model such signals. Here, we present a mean-field...

journal_title：Journal of computational neuroscience

authors： Zerlaut Y,Chemla S,Chavane F,Destexhe A

更新日期：2018-02-01 00:00:00

abstract：:The voltage-gated currents in the fly lobula plate tangential cells were examined using the switched electrode voltage clamp technique. In CH cells, two currents were identified (Figs. 1, 2): a slow calcium inward current and a delayed rectifying, noninactivating potassium outward current. HS and VS cells appear to po...

journal_title：Journal of computational neuroscience

authors： Haag J,Theunissen F,Borst A

更新日期：1997-11-01 00:00:00

abstract：:Many mechanisms of neural processing rely critically upon the synaptic connectivity between neurons. As our ability to simultaneously record from large populations of neurons expands, the ability to infer network connectivity from this data has become a major goal of computational neuroscience. To address this issue, ...

journal_title：Journal of computational neuroscience

authors： Kobayashi R,Kitano K

更新日期：2013-08-01 00:00:00

abstract：:We explore the effects of stochastic sodium (Na) channel activation on the variability and dynamics of spiking and bursting in a model neuron. The complete model segregates Hodgin-Huxley-type currents into two compartments, and undergoes applied current-dependent bifurcations between regimes of periodic bursting, chao...

journal_title：Journal of computational neuroscience

authors： Rowat PF,Elson RC

更新日期：2004-03-01 00:00:00

abstract：:The background activity of a cortical neural network is modeled by a homogeneous integrate-and-fire network with unreliable inhibitory synapses. For the case of fast synapses, numerical and analytical calculations show that the network relaxes into a stationary state of high attention. The majority of the neurons has ...

journal_title：Journal of computational neuroscience

authors： Kinzel W

更新日期：2008-02-01 00:00:00

abstract：:Many neuron types exhibit preferred frequency responses in their voltage amplitude (resonance) or phase shift to subthreshold oscillatory currents, but the effect of biophysical parameters on these properties is not well understood. We propose a general framework to analyze the role of different ionic currents and the...

journal_title：Journal of computational neuroscience

authors： Rotstein HG,Nadim F

更新日期：2014-08-01 00:00:00

abstract：:We present a computational study aimed at exploring the sensorimotor cortex modulation of the behaviour of dorsal column nuclei, specifically the impact of synaptic parameters, during both sleep and waking conditions. On the basis of the circuit proposed by Canedo et al. (2000), we have developed realistic computation...

journal_title：Journal of computational neuroscience

authors： Sánchez E,Barro S,Mariño J,Canedo A

更新日期：2006-08-01 00:00:00

abstract：:During neural development sensory stimulation induces long-term changes in the receptive field of the neurons that encode the stimuli. The Bienenstock-Cooper-Munro (BCM) model was introduced to model and analyze this process computationally, and it remains one of the major models of unsupervised plasticity to this day...

journal_title：Journal of computational neuroscience

authors： Froc M,van Rossum MCW

更新日期：2019-04-01 00:00:00

abstract：:Retinal ganglion cells (RGCs) display differences in their morphology and intrinsic electrophysiology. The goal of this study is to characterize the ionic currents that explain the behavior of ON and OFF RGCs and to explore if all morphological types of RGCs exhibit the phenomena described in electrophysiological data...

journal_title：Journal of computational neuroscience

authors： Maturana MI,Kameneva T,Burkitt AN,Meffin H,Grayden DB

更新日期：2014-04-01 00:00:00

abstract：:We address how spatial frequency selectivity arises in Macaque primary visual cortex (V1) by simulating V1 with a large-scale network model consisting of O(10(4)) excitatory and inhibitory integrate-and-fire neurons with realistic synaptic conductances. The new model introduces variability of the widths of subregions ...

journal_title：Journal of computational neuroscience

authors： Zhu W,Shelley M,Shapley R

更新日期：2009-04-01 00:00:00

abstract：:Prominent models of spike trains assume only one source of variability - stochastic (Poisson) spiking - when stimuli and behavior are fixed. However, spike trains may also reflect variability due to internal processes such as planning. For example, we can plan a movement at one point in time and execute it at some arb...

journal_title：Journal of computational neuroscience

authors： Lawlor PN,Perich MG,Miller LE,Kording KP

更新日期：2018-12-01 00:00:00

abstract：:We developed a multicompartmental Hodgkin-Huxley model of the Hermissenda type-B photoreceptor and used it to address the relative contributions of reductions of two K+ currents, IA and IC, to changes in cellular excitability and synaptic strength that occur in these cells after associative learning. We found that red...

journal_title：Journal of computational neuroscience

authors： Fost JW,Clark GA

更新日期：1996-06-01 00:00:00

abstract：:We have developed compact analog integrated circuits that simulate two synaptic excitatory conductances. A four-transistor circuit captures the dynamics of an excitatory postsynaptic current caused by a real AMPA conductance. A six-transistor circuit simulates the effects of a real voltage-dependent NMDA conductance. ...

journal_title：Journal of computational neuroscience

authors： Rasche C,Douglas RJ

更新日期：1999-07-01 00:00:00

abstract：:The resistive or non-resistive nature of the extracellular space in the brain is still debated, and is an important issue for correctly modeling extracellular potentials. Here, we first show theoretically that if the medium is resistive, the frequency scaling should be the same for electroencephalogram (EEG) and magne...

journal_title：Journal of computational neuroscience

authors： Dehghani N,Bédard C,Cash SS,Halgren E,Destexhe A

更新日期：2010-06-17 00:00:00

abstract：:One of the most common examples of audiovisual speech integration is the McGurk effect. As an example, an auditory syllable /ba/ recorded over incongruent lip movements that produce "ga" typically causes listeners to hear "da". This report hypothesizes reasons why certain clinical and listeners who are hard of hearing...

journal_title：Journal of computational neuroscience

authors： Altieri N,Yang CT

更新日期：2016-10-01 00:00:00

abstract：:During posture control, reflexive feedback allows humans to efficiently compensate for unpredictable mechanical disturbances. Although reflexes are involuntary, humans can adapt their reflexive settings to the characteristics of the disturbances. Reflex modulation is commonly studied by determining reflex gains: a set...

journal_title：Journal of computational neuroscience

authors： Schuurmans J,van der Helm FC,Schouten AC

更新日期：2011-06-01 00:00:00

abstract：:The influence of unreliable synapses on the dynamic properties of a neural network is investigated for a homogeneous integrate-and-fire network with delayed inhibitory synapses. Numerical and analytical calculations show that the network relaxes to a state with dynamic clusters of identical size which permanently exch...

journal_title：Journal of computational neuroscience

authors： Friedrich J,Kinzel W

更新日期：2009-08-01 00:00:00

abstract：:Several neuron types have been shown to exhibit (subthreshold) membrane potential resonance (MPR), defined as the occurrence of a peak in their voltage amplitude response to oscillatory input currents at a preferred (resonant) frequency. MPR has been investigated both experimentally and theoretically. However, whether...

journal_title：Journal of computational neuroscience

authors： Bel A,Rotstein HG

更新日期：2019-04-01 00:00:00

abstract：:The timing of transmitter release from nerve endings is considered nowadays as one of the factors determining the plasticity and efficacy of synaptic transmission. In the neuromuscular junction, the moments of release of individual acetylcholine quanta are related to the synaptic delays of uniquantal endplate currents...

journal_title：Journal of computational neuroscience

authors： Saveliev A,Khuzakhmetova V,Samigullin D,Skorinkin A,Kovyazina I,Nikolsky E,Bukharaeva E

更新日期：2015-10-01 00:00:00

abstract：:We construct a neuronal network to model the logic of associative conditioning as revealed in experimental results using the terrestrial mollusk Limax maximus. We show, in particular, how blocking to a previously conditioned stimulus in the presence of the unconditional stimulus, can emerge as a dynamical property of ...

journal_title：Journal of computational neuroscience

authors： Goel P,Gelperin A

更新日期：2006-12-01 00:00:00

abstract：:A Web-based simulation system of the spinal cord circuitry responsible for muscle control is described. The simulator employs two-compartment motoneuron models for S, FR and FF types, with synaptic inputs acting through conductance variations. Four motoneuron pools with their associated interneurons are represented in...

journal_title：Journal of computational neuroscience

authors： Cisi RR,Kohn AF

更新日期：2008-12-01 00:00:00

abstract：:The calcium calmodulin dependent kinase (CaMKII) is important for long-term potentiation at dendritic spines. Photo-activatable GFP (PaGFP) - CaMKII fusions were used to map CaMKII movements between and within spines in dissociated hippocampal neurons. Photo-activated PaGFP (GFP*) generated in the shaft spread uniform...

journal_title：Journal of computational neuroscience

authors： Khan S,Reese TS,Rajpoot N,Shabbir A

更新日期：2012-08-01 00:00:00

abstract：:Neural mass models are successful in modeling brain rhythms as observed in macroscopic measurements such as the electroencephalogram (EEG). While the synaptic current is explicitly modeled in current models, the single cell electrophysiology is not taken into account. To allow for investigations of the effects of chan...

journal_title：Journal of computational neuroscience

authors： Zandt BJ,Visser S,van Putten MJ,Ten Haken B

更新日期：2014-12-01 00:00:00

abstract：:In this paper, we systematically investigate both the synfire propagation and firing rate propagation in feedforward neuronal network coupled in an all-to-all fashion. In contrast to most earlier work, where only reliable synaptic connections are considered, we mainly examine the effects of unreliable synapses on both...

journal_title：Journal of computational neuroscience

authors： Guo D,Li C

更新日期：2011-06-01 00:00:00