Modeling Hermissenda: I. Differential contributions of IA and IC to type-B cell plasticity.

abstract：:One of the most common examples of audiovisual speech integration is the McGurk effect. As an example, an auditory syllable /ba/ recorded over incongruent lip movements that produce "ga" typically causes listeners to hear "da". This report hypothesizes reasons why certain clinical and listeners who are hard of hearing...

journal_title：Journal of computational neuroscience

authors： Altieri N,Yang CT

更新日期：2016-10-01 00:00:00

abstract：:Several neuron types have been shown to exhibit (subthreshold) membrane potential resonance (MPR), defined as the occurrence of a peak in their voltage amplitude response to oscillatory input currents at a preferred (resonant) frequency. MPR has been investigated both experimentally and theoretically. However, whether...

journal_title：Journal of computational neuroscience

authors： Bel A,Rotstein HG

更新日期：2019-04-01 00:00:00

abstract：:Wider dissemination and testing of computational models are crucial to the field of computational neuroscience. Databases are being developed to meet this need. ModelDB is a web-accessible database for convenient entry, retrieval, and running of published models on different platforms. This article provides a guide to...

journal_title：Journal of computational neuroscience

authors： Hines ML,Morse T,Migliore M,Carnevale NT,Shepherd GM

更新日期：2004-07-01 00:00:00

abstract：:Neuron modeling may be said to have originated with the Hodgkin and Huxley action potential model in 1952 and Rall's models of integrative activity of dendrites in 1964. Over the ensuing decades, these approaches have led to a massive development of increasingly accurate and complex data-based models of neurons and ne...

journal_title：Journal of computational neuroscience

authors： McDougal RA,Morse TM,Carnevale T,Marenco L,Wang R,Migliore M,Miller PL,Shepherd GM,Hines ML

更新日期：2017-02-01 00:00:00

abstract：:Gamma oscillations can synchronize with near zero phase lag over multiple cortical regions and between hemispheres, and between two distal sites in hippocampal slices. How synchronization can take place over long distances in a stable manner is considered an open question. The phase resetting curve (PRC) keeps track o...

journal_title：Journal of computational neuroscience

authors： Woodman MM,Canavier CC

更新日期：2011-10-01 00:00:00

abstract：:We present a multi-input multi-output neural circuit architecture for nonlinear processing and encoding of stimuli in the spike domain. In this architecture a bank of dendritic stimulus processors implements nonlinear transformations of multiple temporal or spatio-temporal signals such as spike trains or auditory and ...

journal_title：Journal of computational neuroscience

authors： Lazar AA,Slutskiy YB

更新日期：2015-02-01 00:00:00

abstract：:We construct a neuronal network to model the logic of associative conditioning as revealed in experimental results using the terrestrial mollusk Limax maximus. We show, in particular, how blocking to a previously conditioned stimulus in the presence of the unconditional stimulus, can emerge as a dynamical property of ...

journal_title：Journal of computational neuroscience

authors： Goel P,Gelperin A

更新日期：2006-12-01 00:00:00

abstract：:Epilepsy is one of the most common neurological disorders and is characterized by recurrent seizures. We use theoretical neuroscience tools to study brain dynamics during seizures. We derive and simulate a computational model of a network of hippocampal neuronal populations. Each population within the network is based...

journal_title：Journal of computational neuroscience

authors： Kameneva T,Ying T,Guo B,Freestone DR

更新日期：2017-04-01 00:00:00

abstract：:Inhibitory networks are now recognized as being the controllers of several brain rhythms. However, experimental work with inhibitory cells is technically difficult not only because of their smaller percentage of the neuronal population, but also because of their diverse properties. As such, inhibitory network models w...

journal_title：Journal of computational neuroscience

authors： Skinner FK,Bazzazi H,Campbell SA

更新日期：2005-06-01 00:00:00

abstract：:We study the dynamics and bifurcations of noise-free neurons coupled by gap junctions and inhibitory synapses, using both delayed delta functions and alpha functions to model the latter. We focus on the case of two cells, as in the studies of Chow and Kopell (2000) and Lewis and Rinzel (2003), but also show that stabl...

journal_title：Journal of computational neuroscience

authors： Gao J,Holmes P

更新日期：2007-02-01 00:00:00

abstract：:Characterizing how different cortical rhythms interact and how their interaction changes with sensory stimulation is important to gather insights into how these rhythms are generated and what sensory function they may play. Concepts from information theory, such as Transfer Entropy (TE), offer principled ways to quant...

journal_title：Journal of computational neuroscience

authors： Besserve M,Schölkopf B,Logothetis NK,Panzeri S

更新日期：2010-12-01 00:00:00

abstract：:Voltage-sensitive dye imaging (VSDi) has revealed fundamental properties of neocortical processing at macroscopic scales. Since for each pixel VSDi signals report the average membrane potential over hundreds of neurons, it seems natural to use a mean-field formalism to model such signals. Here, we present a mean-field...

journal_title：Journal of computational neuroscience

authors： Zerlaut Y,Chemla S,Chavane F,Destexhe A

更新日期：2018-02-01 00:00:00

abstract：:It is widely believed that the theta rhythm in the hippocampus is caused by the rhythmic input from the medial septum-diagonal band of Broca (MSDB). The main MSDB output is formed by GABAergic projection neurons which are divided into two subpopulations and fire at different phases of the hippocampal theta rhythm. The...

journal_title：Journal of computational neuroscience

authors： Mysin IE,Kitchigina VF,Kazanovich Y

更新日期：2015-08-01 00:00:00

abstract：:Avian brain area HVC is known to be important for the production of birdsong. In zebra finches, each RA-projecting neuron in HVC emits a single burst of spikes during a song motif. The population of neurons is activated in a precisely timed, stereotyped sequence. We propose a model of these burst sequences that relies...

journal_title：Journal of computational neuroscience

authors： Jin DZ,Ramazanoğlu FM,Seung HS

更新日期：2007-12-01 00:00:00

abstract：:In this paper, we systematically investigate both the synfire propagation and firing rate propagation in feedforward neuronal network coupled in an all-to-all fashion. In contrast to most earlier work, where only reliable synaptic connections are considered, we mainly examine the effects of unreliable synapses on both...

journal_title：Journal of computational neuroscience

authors： Guo D,Li C

更新日期：2011-06-01 00:00:00

abstract：:With the advancement in computer technology, it has become possible to fit complex models to neuronal data. In this work, we test how two methods can estimate parameters of simple neuron models (passive soma) to more complex ones (neuron with one dendritic cylinder and two active conductances). The first method uses c...

journal_title：Journal of computational neuroscience

authors： Tabak J,Murphey CR,Moore LE

更新日期：2000-11-01 00:00:00

abstract：:Computational modeling of dendritic morphology is a powerful tool for quantitatively describing complex geometrical relationships, uncovering principles of dendritic development, and synthesizing virtual neurons to systematically investigate cellular biophysics and network dynamics. A feature common to many morphologi...

journal_title：Journal of computational neuroscience

authors： Donohue DE,Ascoli GA

更新日期：2005-10-01 00:00:00

abstract：:We present a model for the use of open loop optogenetic control to inhibit epileptiform activity in a meso scale model of the human cortex. The meso scale cortical model first developed by Liley et al. (2001) is extended to two dimensions and the nature of the seizure waves is studied. We adapt to the meso scale a 4 s...

journal_title：Journal of computational neuroscience

authors： Selvaraj P,Sleigh JW,Freeman WJ,Kirsch HE,Szeri AJ

更新日期：2014-06-01 00:00:00

abstract：:We address how spatial frequency selectivity arises in Macaque primary visual cortex (V1) by simulating V1 with a large-scale network model consisting of O(10(4)) excitatory and inhibitory integrate-and-fire neurons with realistic synaptic conductances. The new model introduces variability of the widths of subregions ...

journal_title：Journal of computational neuroscience

authors： Zhu W,Shelley M,Shapley R

更新日期：2009-04-01 00:00:00

abstract：:The resistive or non-resistive nature of the extracellular space in the brain is still debated, and is an important issue for correctly modeling extracellular potentials. Here, we first show theoretically that if the medium is resistive, the frequency scaling should be the same for electroencephalogram (EEG) and magne...

journal_title：Journal of computational neuroscience

authors： Dehghani N,Bédard C,Cash SS,Halgren E,Destexhe A

更新日期：2010-12-01 00:00:00

abstract：:Many neuron types exhibit preferred frequency responses in their voltage amplitude (resonance) or phase shift to subthreshold oscillatory currents, but the effect of biophysical parameters on these properties is not well understood. We propose a general framework to analyze the role of different ionic currents and the...

journal_title：Journal of computational neuroscience

authors： Rotstein HG,Nadim F

更新日期：2014-08-01 00:00:00

abstract：:Most neurons in the primary visual cortex initially respond vigorously when a preferred stimulus is presented, but adapt as stimulation continues. The functional consequences of adaptation are unclear. Typically a reduction of firing rate would reduce single neuron accuracy as less spikes are available for decoding, b...

journal_title：Journal of computational neuroscience

authors： Cortes JM,Marinazzo D,Series P,Oram MW,Sejnowski TJ,van Rossum MC

更新日期：2012-06-01 00:00:00

abstract：:We present a computational study aimed at exploring the sensorimotor cortex modulation of the behaviour of dorsal column nuclei, specifically the impact of synaptic parameters, during both sleep and waking conditions. On the basis of the circuit proposed by Canedo et al. (2000), we have developed realistic computation...

journal_title：Journal of computational neuroscience

authors： Sánchez E,Barro S,Mariño J,Canedo A

更新日期：2006-08-01 00:00:00

abstract：:We have previously formulated an abstract dynamical system for networks of spiking neurons and derived a formal result that identifies the criterion for its dynamics, without inputs, to be "sensitive to initial conditions". Since formal results are applicable only to the extent to which their assumptions are valid, we...

journal_title：Journal of computational neuroscience

authors： Banerjee A

更新日期：2006-06-01 00:00:00

abstract：:Information maximization has long been suggested as the underlying coding strategy of the primary visual cortex (V1). Grouping image sequences into blocks has been shown by others to improve agreement between experiments and theory. We have studied the effect of temporal convolution on the formation of spatiotemporal ...

journal_title：Journal of computational neuroscience

authors： Szatmáry B,Lorincz A

更新日期：2001-11-01 00:00:00

abstract：:Retinal ganglion cells (RGCs) display differences in their morphology and intrinsic electrophysiology. The goal of this study is to characterize the ionic currents that explain the behavior of ON and OFF RGCs and to explore if all morphological types of RGCs exhibit the phenomena described in electrophysiological data...

journal_title：Journal of computational neuroscience

authors： Maturana MI,Kameneva T,Burkitt AN,Meffin H,Grayden DB

更新日期：2014-04-01 00:00:00

abstract：:Confirming that synaptic loss is directly related to cognitive deficit in Alzheimer's disease (AD) has been the focus of many studies. Compensation mechanisms counteract synaptic loss and prevent the catastrophic amnesia induced by synaptic loss via maintaining the activity levels of neural circuits. Here we investiga...

journal_title：Journal of computational neuroscience

authors： Abuhassan K,Coyle D,Belatreche A,Maguire L

更新日期：2014-02-01 00:00:00

abstract：:Waves have long been thought to be a fundamental mechanism for communicating information within a medium and are widely observed in biological systems. However, a quantitative analysis of biological waves is confounded by the variability and complexity of the response. This paper proposes a robust technique for extrac...

journal_title：Journal of computational neuroscience

authors： Robbins KA,Senseman DM

更新日期：2004-05-01 00:00:00

abstract：:We have developed compact analog integrated circuits that simulate two synaptic excitatory conductances. A four-transistor circuit captures the dynamics of an excitatory postsynaptic current caused by a real AMPA conductance. A six-transistor circuit simulates the effects of a real voltage-dependent NMDA conductance. ...

journal_title：Journal of computational neuroscience

authors： Rasche C,Douglas RJ

更新日期：1999-07-01 00:00:00

abstract：:Transcranial Direct brain stimulation (tDCS) is commonly used in order to modulate cortical networks activity during physiological processes through the application of weak electrical fields with scalp electrodes. Cathodal stimulation has been shown to decrease brain excitability in the context of epilepsy, with varia...

journal_title：Journal of computational neuroscience

authors： Denoyer Y,Merlet I,Wendling F,Benquet P

更新日期：2020-05-01 00:00:00