Modeling the influence of optic flow on grid cell firing in the absence of other cues1.

abstract：:The firing rate of neurons in parietal area 7a of the behaving Rhesus monkey with its head fixed incorporates both visual and eye position information. This neural tuning is not in an ego-centered coordinate space. This physiological result was unexpected as behavioral deficits following parietal damage in human and m...

journal_title：Journal of computational neuroscience

authors： Siegel RM

更新日期：1998-12-01 00:00:00

abstract：:A population of uncoupled neurons can often be brought close to synchrony by a single strong inhibitory input pulse affecting all neurons equally. This mechanism is thought to underlie some brain rhythms, in particular gamma frequency (30-80 Hz) oscillations in the hippocampus and neocortex. Here we show that synchron...

journal_title：Journal of computational neuroscience

authors： Börgers C,Krupa M,Gielen S

更新日期：2010-06-01 00:00:00

abstract：:Networks of hippocampal interneurons, with pyramidal neurons pharmacologically disconnected, can generate gamma-frequency (20 Hz and above) oscillations. Experiments and models have shown how the network frequency depends on excitation of the interneurons, and on the parameters of GABAA-mediated IPSCs between the inte...

journal_title：Journal of computational neuroscience

authors： Traub RD,Jefferys JG,Whittington MA

更新日期：1997-04-01 00:00:00

abstract：:This work presents a neuroinformatic method for deriving mechanistic descriptions of fine-structured neural activity. This is a new development in the computer-assisted analysis of dynamics in conductance-based models, which is illustrated using single compartment models of an action potential. A sequence of abstract,...

journal_title：Journal of computational neuroscience

authors： Clewley R

更新日期：2011-04-01 00:00:00

abstract：:The pathophysiology of auditory hallucination, a common symptom of schizophrenia, has yet been understood, but during auditory hallucination, primary auditory cortex (A1) shows paradoxical responses. When auditory stimuli are absent, A1 becomes hyperactive, while A1 responses to auditory stimuli are reduced. Such acti...

journal_title：Journal of computational neuroscience

authors： Lee JH

更新日期：2017-12-01 00:00:00

abstract：:We explore the effects of stochastic sodium (Na) channel activation on the variability and dynamics of spiking and bursting in a model neuron. The complete model segregates Hodgin-Huxley-type currents into two compartments, and undergoes applied current-dependent bifurcations between regimes of periodic bursting, chao...

journal_title：Journal of computational neuroscience

authors： Rowat PF,Elson RC

更新日期：2004-03-01 00:00:00

abstract：:The voltage-gated currents in the fly lobula plate tangential cells were examined using the switched electrode voltage clamp technique. In CH cells, two currents were identified (Figs. 1, 2): a slow calcium inward current and a delayed rectifying, noninactivating potassium outward current. HS and VS cells appear to po...

journal_title：Journal of computational neuroscience

authors： Haag J,Theunissen F,Borst A

更新日期：1997-11-01 00:00:00

abstract：:Calmodulin (CaM) is a major Ca(2+) binding protein involved in two opposing processes of synaptic plasticity of CA1 pyramidal neurons: long-term potentiation (LTP) and depression (LTD). The N- and C-terminal lobes of CaM bind to its target separately but cooperatively and introduce complex dynamics that cannot be well...

journal_title：Journal of computational neuroscience

authors： Byrne MJ,Putkey JA,Waxham MN,Kubota Y

更新日期：2009-12-01 00:00:00

abstract：:This work presents a probabilistic method for inferring the parameter ranges in a biologically relevant mathematical model of the cortex most likely to be producing seizures observed in an electrocorticogram (ECoG) signal from a human subject. Additionally, this method produces a probabilistic pathway of the temporal ...

journal_title：Journal of computational neuroscience

authors： Dadok VM,Kirsch HE,Sleigh JW,Lopour BA,Szeri AJ

更新日期：2015-06-01 00:00:00

abstract：:Characterizing how different cortical rhythms interact and how their interaction changes with sensory stimulation is important to gather insights into how these rhythms are generated and what sensory function they may play. Concepts from information theory, such as Transfer Entropy (TE), offer principled ways to quant...

journal_title：Journal of computational neuroscience

authors： Besserve M,Schölkopf B,Logothetis NK,Panzeri S

更新日期：2010-12-01 00:00:00

abstract：:We investigate the use of extracellular action potential (EAP) recordings for biophysically faithful compartmental models. We ask whether constraining a model to fit the EAP is superior to matching the intracellular action potential (IAP). In agreement with previous studies, we find that the IAP method under-constrain...

journal_title：Journal of computational neuroscience

authors： Gold C,Henze DA,Koch C

更新日期：2007-08-01 00:00:00

abstract：:The paper presents a hierarchical series of computational models for myelinated axonal compartments. Three classes of models are considered, either with distributed parameters (2.5D EQS-ElectroQuasi Static, 1D TL-Transmission Lines) or with lumped parameters (0D). They are systematically analyzed with both analytical ...

journal_title：Journal of computational neuroscience

authors： Ioan D,Bărbulescu R,Silveira LM,Ciuprina G

更新日期：2019-12-01 00:00:00

abstract：:This paper presents a synergistic parametric and non-parametric modeling study of short-term plasticity (STP) in the Schaffer collateral to hippocampal CA1 pyramidal neuron (SC) synapse. Parametric models in the form of sets of differential and algebraic equations have been proposed on the basis of the current underst...

journal_title：Journal of computational neuroscience

authors： Song D,Wang Z,Marmarelis VZ,Berger TW

更新日期：2009-02-01 00:00:00

abstract：:During slow-wave sleep, brain electrical activity is dominated by the slow (< 1 Hz) electroencephalogram (EEG) oscillations characterized by the periodic transitions between active (or Up) and silent (or Down) states in the membrane voltage of the cortical and thalamic neurons. Sleep slow oscillation is believed to pl...

journal_title：Journal of computational neuroscience

authors： Komarov M,Krishnan G,Chauvette S,Rulkov N,Timofeev I,Bazhenov M

更新日期：2018-02-01 00:00:00

abstract：:The effect of a non-symmetric waveform on nerve conduction block induced by high-frequency biphasic stimulation is investigated using a lumped circuit model of the unmyelinated axon based on Hodgkin-Huxley equations. The simulation results reveal that the block threshold monotonically increases with the stimulation fr...

journal_title：Journal of computational neuroscience

authors： Zhao S,Yang G,Wang J,Roppolo JR,de Groat WC,Tai C

更新日期：2014-10-01 00:00:00

abstract：:Neuronal responses are often characterized by the firing rate as a function of the stimulus mean, or the f-I curve. We introduce a novel classification of neurons into Types A, B-, and B+ according to how f-I curves are modulated by input fluctuations. In Type A neurons, the f-I curves display little sensitivity to in...

journal_title：Journal of computational neuroscience

authors： Lundstrom BN,Famulare M,Sorensen LB,Spain WJ,Fairhall AL

更新日期：2009-10-01 00:00:00

abstract：:Computational modeling of dendritic morphology is a powerful tool for quantitatively describing complex geometrical relationships, uncovering principles of dendritic development, and synthesizing virtual neurons to systematically investigate cellular biophysics and network dynamics. A feature common to many morphologi...

journal_title：Journal of computational neuroscience

authors： Donohue DE,Ascoli GA

更新日期：2005-10-01 00:00:00

abstract：:One of the most common examples of audiovisual speech integration is the McGurk effect. As an example, an auditory syllable /ba/ recorded over incongruent lip movements that produce "ga" typically causes listeners to hear "da". This report hypothesizes reasons why certain clinical and listeners who are hard of hearing...

journal_title：Journal of computational neuroscience

authors： Altieri N,Yang CT

更新日期：2016-10-01 00:00:00

abstract：:Many neuronal systems exhibit slow random alternations and sudden switches in activity states. Models with noisy relaxation dynamics (oscillatory, excitable or bistable) account for these temporal, slow wave, patterns and the fluctuations within states. The noise-induced transitions in a relaxation dynamics are analog...

journal_title：Journal of computational neuroscience

authors： Lim S,Rinzel J

更新日期：2010-02-01 00:00:00

abstract：:Much evidence indicates that recognition memory involves two separable processes, recollection and familiarity discrimination, with familiarity discrimination being dependent on the perirhinal cortex of the temporal lobe. Here, we describe a new neural network model designed to mimic the response patterns of perirhina...

journal_title：Journal of computational neuroscience

authors： Bogacz R,Brown MW,Giraud-Carrier C

更新日期：2001-01-01 00:00:00

abstract：:We address how spatial frequency selectivity arises in Macaque primary visual cortex (V1) by simulating V1 with a large-scale network model consisting of O(10(4)) excitatory and inhibitory integrate-and-fire neurons with realistic synaptic conductances. The new model introduces variability of the widths of subregions ...

journal_title：Journal of computational neuroscience

authors： Zhu W,Shelley M,Shapley R

更新日期：2009-04-01 00:00:00

abstract：:We construct a neuronal network to model the logic of associative conditioning as revealed in experimental results using the terrestrial mollusk Limax maximus. We show, in particular, how blocking to a previously conditioned stimulus in the presence of the unconditional stimulus, can emerge as a dynamical property of ...

journal_title：Journal of computational neuroscience

authors： Goel P,Gelperin A

更新日期：2006-12-01 00:00:00

abstract：:We have presented a new generation mechanism of slow spiking or repetitive discharges with extraordinarily long inter-spike intervals using the modified Hodgkin-Huxley equations (Doi and Kumagai, 2001). This generation process of slow firing is completely different from that of the well-known potassium A-current in th...

journal_title：Journal of computational neuroscience

authors： Doi S,Kumagai S

更新日期：2005-12-01 00:00:00

abstract：:Neural mass models are successful in modeling brain rhythms as observed in macroscopic measurements such as the electroencephalogram (EEG). While the synaptic current is explicitly modeled in current models, the single cell electrophysiology is not taken into account. To allow for investigations of the effects of chan...

journal_title：Journal of computational neuroscience

authors： Zandt BJ,Visser S,van Putten MJ,Ten Haken B

更新日期：2014-12-01 00:00:00

abstract：:Phase precession is one of the most well known examples within the temporal coding hypothesis. Here we present a biophysical spiking model for phase precession in hippocampal CA1 which focuses on the interaction between place cells and local inhibitory interneurons. The model's functional block is composed of a place ...

journal_title：Journal of computational neuroscience

authors： Castro L,Aguiar P

更新日期：2012-08-01 00:00:00

abstract：:Inhibitory networks are now recognized as being the controllers of several brain rhythms. However, experimental work with inhibitory cells is technically difficult not only because of their smaller percentage of the neuronal population, but also because of their diverse properties. As such, inhibitory network models w...

journal_title：Journal of computational neuroscience

authors： Skinner FK,Bazzazi H,Campbell SA

更新日期：2005-06-01 00:00:00

abstract：:Within the theory that describes the hippocampus as a device for the on-line storage of complex memories, the crucial autoassociative operations are ascribed mainly to the recurrent CA3 network. The CA3-to-CA1 connections may still be important, both in completing information retrieval and in re-expanding, with minima...

journal_title：Journal of computational neuroscience

authors： Treves A

更新日期：1995-09-01 00:00:00

abstract：:An analytical model is proposed that can predict the shape of the poststimulus time histogram (PSTH) response to a current pulse of a neuron subjected to uncorrelated background input. The model is based on an explicit description of noise in the form of an escape rate and corresponding hazard function. Two forms of t...

journal_title：Journal of computational neuroscience

authors： Herrmann A,Gerstner W

更新日期：2001-09-01 00:00:00

abstract：:We propose a new retina simulation software, called Virtual Retina, which transforms a video into spike trains. Our goal is twofold: Allow large scale simulations (up to 100,000 neurons) in reasonable processing times and keep a strong biological plausibility, taking into account implementation constraints. The underl...

journal_title：Journal of computational neuroscience

authors： Wohrer A,Kornprobst P

更新日期：2009-04-01 00:00:00

abstract：:The implications for motor learning of the model developed in the previous article are analyzed using idealized Pavlovian eyelid conditioning trials, a simple example of cerebellar motor learning. Results suggest that changes in gr-->Pkj synapses produced by a training trial disrupt equilibrium and lead to subsequent ...

journal_title：Journal of computational neuroscience

authors： Kenyon GT,Medina JF,Mauk MD

更新日期：1998-03-01 00:00:00