Abstract：
:Condensed pyrazole derivatives are important heterocyclic compounds due to their excellent biological activities and have been widely applied in pharmaceutical and agromedical fields. In recent years, numerous condensed pyrazole derivatives have been synthesized and advanced to clinic studies with various biological activities. In this review, we summarized the reported synthesis methods of condensed pyrazole derivatives from 2010 until now. All compounds are divided into three parts according to the rings connected to pyrazole-ring, i.e. [5, 5], [5,F 6], and [5, 7]-condensed pyrazole derivatives. The biological activities and applications in pharmaceutical fields are briefly introduced to offer an orientation for the design and synthesis of condensed pyrazole derivatives with good biological activities.
journal_name
Eur J Med Chemjournal_title
European journal of medicinal chemistryauthors
Li M,Zhao BXdoi
10.1016/j.ejmech.2014.07.102subject
Has Abstractpub_date
2014-10-06 00:00:00pages
311-40eissn
0223-5234issn
1768-3254pii
S0223-5234(14)00717-Xjournal_volume
85pub_type
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