Tranylcypromine vs nortriptyline vs placebo in depressed outpatients: a controlled trial.

abstract：:In the present study a cross-familiarisation conditioned taste aversion (CTA) paradigm was utilized to reveal stimulus resemblance between the selective 5-HT1A agonist 8-OHDPAT and a variety of serotonergic and non-serotonergic drugs. In male mice, a 0.22 mg/kg dose of 8-OHDPAT was used as the reference compound induc...

journal_title：Psychopharmacology

authors： De Beun R,Rijk HW,Broekkamp CL

更新日期：1993-01-01 00:00:00

abstract：:In the studies reported here, we investigated the effects of nicotine on memory for unrelated word lists. Nicotine was delivered through cigarette smoking, and memory performance was assessed using both intentional and incidental recall tasks, and employing an additional, indirect measure of memory. We report the resu...

journal_title：Psychopharmacology

authors： Rusted J,Graupner L,Warburton D

更新日期：1995-06-01 00:00:00

abstract：RATIONALE:Despite consistent evidence of the familiality of substance misuse, the mechanisms by which family history (FH) increases the risk of addiction are not well understood. One behavioral trait that may mediate the risk for substance use and addiction is delay discounting (DD), which characterizes an individual's...

journal_title：Psychopharmacology

authors： VanderBroek L,Acker J,Palmer AA,de Wit H,MacKillop J

更新日期：2016-01-01 00:00:00

abstract：RATIONALE:The effects of caffeine, especially caffeinated coffee, on human performance have been extensively studied. However, few studies have been naturalistic representations of how tea/coffee is normally consumed in terms of dose and time of consumption. OBJECTIVES:This study investigated the effects of day-long c...

journal_title：Psychopharmacology

authors： Hindmarch I,Rigney U,Stanley N,Quinlan P,Rycroft J,Lane J

更新日期：2000-04-01 00:00:00

abstract：RATIONALE:Past research has found that exposure to alcohol cues causes a narrowing of attentional scope and enhances the neural responses associated with approach motivation. OBJECTIVE:The current research sought to determine if a manipulated broadened (global) attentional scope would reduce approach-motivated neural ...

journal_title：Psychopharmacology

authors： Ryerson NC,Neal LB,Gable PA

更新日期：2017-04-01 00:00:00

abstract：RATIONALE:Several halogenated analogs of benztropine (BZT) have previously been characterized as potent DA uptake inhibitors with behavioral profiles that indicate diminished psychomotor stimulant effects relative to cocaine. In a previous study using a fixed-ratio 10 schedule, two chloro-analogs (3'-Cl-BZT and 4'-Cl-B...

journal_title：Psychopharmacology

authors： Woolverton WL,Hecht GS,Agoston GE,Katz JL,Newman AH

更新日期：2001-04-01 00:00:00

abstract：RATIONALE:N-methyl-D-aspartate (NMDA) receptor antagonists (e.g., PCP, ketamine) have been shown to impair learning/memory. Well documented in animal models, only limited research in humans has been reported. Findings to date are similar to results of animal studies; however, antagonists are typically administered befo...

journal_title：Psychopharmacology

authors： LaPorte DJ,Blaxton TA,Michaelidis T,Robertson DU,Weiler MA,Tamminga CA,Lahti AC

更新日期：2005-07-01 00:00:00

abstract：:Phencyclidine combined with footshock stress produced a greater increase in the homovanillic acid content of prefrontal cortex than either phencyclidine or footshock alone. Phencyclidine decreased both substance P and substance K in the ventral tegmental area. The results suggest that phencyclidine and footshock activ...

journal_title：Psychopharmacology

authors： Bowers MB Jr,Bannon MJ,Hoffman FJ Jr

更新日期：1987-01-01 00:00:00

abstract：RATIONALE/OBJECTIVES:Previous research has shown that ecstasy users are impaired in thinking and reasoning. The present study sought to explore the possibility that syllogistic reasoning errors in ecstasy users were due to an inability to construct a model of the premises due to working memory limitations. METHODS:Twe...

journal_title：Psychopharmacology

authors： Fisk JE,Montgomery C,Wareing M,Murphy PN

更新日期：2005-09-01 00:00:00

abstract：:Methadone as the most prevalent opioid substitution medication has been shown to influence the neurophysiological functions among heroin addicts. However, there is no firm conclusion on acute neuroelectrophysiological changes among methadone-treated subjects as well as the effectiveness of methadone in restoring brain...

journal_title：Psychopharmacology

authors： Motlagh F,Ibrahim F,Rashid R,Shafiabady N,Seghatoleslam T,Habil H

更新日期：2018-11-01 00:00:00

abstract：:Roxindole is a potent autoreceptor-selective dopamine agonist with additional properties as a serotonin reuptake inhibitor and 5-HT1A agonist. In order to get more insight into its mode of action in various psychiatric populations, we evaluated the effects of subchronic roxindole treatment on pituitary and adrenal hor...

journal_title：Psychopharmacology

authors： Gründer G,Wetzel H,Hillert A,Jochum E,Hiemke C,Benkert O

更新日期：1995-02-01 00:00:00

abstract：:Voluntary consumption of alcohol by rats (i.e. in the absence of food or water deprivation, sweetening of the alcohol solution, etc.) that results in the attainment of behaviorally significant or pharmacologically detectable blood alcohol levels (BALs) has been difficult to demonstrate. In this study, we showed that f...

journal_title：Psychopharmacology

authors： Linseman MA

更新日期：1987-01-01 00:00:00

abstract：:The effects of dopamine agonists on self-stimulation are a matter of considerable dispute. Apomorphine has variously been reported to inhibit, have no effect on, or to facilitate lever-press self-stimulation. To investigate the possibility that these discrepancies may reflect peculiarities of the lever-press test situ...

journal_title：Psychopharmacology

authors： Atrens DM,Becker FT,Hunt GE

更新日期：1980-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Footshock stress reliably reinstates heroin seeking in rats, but the time course of the development of this effect following drug withdrawal is not known. Here we studied the effect of intermittent footshock stress on reinstatement of heroin seeking following different withdrawal periods (1-66 ...

journal_title：Psychopharmacology

authors： Shalev U,Morales M,Hope B,Yap J,Shaham Y

更新日期：2001-06-01 00:00:00

abstract：INTRODUCTION:A growing number of studies have found evidence that anxiety and depressive disorders are associated with atypical amygdala hyperactivation, which decreases with effective treatment. Interest has emerged in this phenomenon as a possible biological marker for individuals who are likely to benefit from tailo...

journal_title：Psychopharmacology

authors： McClure EB,Adler A,Monk CS,Cameron J,Smith S,Nelson EE,Leibenluft E,Ernst M,Pine DS

更新日期：2007-03-01 00:00:00

abstract：:3,4-Methylenedioxymethamphetamine (MDMA) is a psychoactive phenylisopropylamine which is structurally similar to both amphetamine-related sympathomimetics and the hallucinogen, mescaline. MDMA produces pleasurable effects which include euphoria, and recent reports continue to demonstrate its widespread recreational us...

journal_title：Psychopharmacology

authors： Hubner CB,Bird M,Rassnick S,Kornetsky C

更新日期：1988-01-01 00:00:00

abstract：RATIONALE:Nicotine improves cognitive function in a number of animal models including rats, mice, monkeys, and recently, zebrafish. The zebrafish model allows higher throughput and ease in discovering mechanisms of cognitive improvement. MATERIALS AND METHODS:To further characterize the neural bases of nicotine effect...

journal_title：Psychopharmacology

authors： Eddins D,Petro A,Williams P,Cerutti DT,Levin ED

更新日期：2009-01-01 00:00:00

abstract：RATIONALE:Interrelationships between the discriminative stimulus and reinforcing properties of psychoactive drugs and the way in which they may interact to control drug intake are unclear. Studies have shown that drug history can influence the expression of drug-produced behavioral effects. OBJECTIVE:The present study...

journal_title：Psychopharmacology

authors： Childs E,Shoaib M,Stolerman IP

更新日期：2006-06-01 00:00:00

abstract：:The aim of the present study was to (i) characterise the mouse behavioural profile (particularly social interactions) during the preweaning period, (ii) assess the effects of prenatal exposure to an anticonvulsant drug widely used in clinical practice, (iii) examine possible genetic differences both in baseline behavi...

journal_title：Psychopharmacology

authors： Laviola G,Terranova ML,Sedowofia K,Clayton R,Manning A

更新日期：1994-01-01 00:00:00

abstract：:The time course of light adaptation after intense light exposure is significantly delayed by alcohol, marijuana, and a combined dose of alcohol and marijuana. These effects were found in a double blind experiment, using 10 subjects. The experimental treatments were placebo, 0.75 ml/kg of 95% ethanol, 8 and 15 mg of de...

journal_title：Psychopharmacology

authors： Adams AJ,Brown B,Haegerstrom-Portnoy G,Flom MC,Jones RT

更新日期：1978-01-31 00:00:00

abstract：:The antipsychotic drugs haloperidol and clozapine have the common action of increasing dopamine metabolism in the striatum (nucleus accumbens, caudate-putamen) of the rat. Intracerebroventricular administration of kainic acid (KA) produces neuronal loss in limbic-cortical brain regions which project directly or indire...

journal_title：Psychopharmacology

authors： Bardgett ME,Salaris SL,Jackson JL,Harding J,Csernansky JG

更新日期：1997-09-01 00:00:00

abstract：RATIONALE:Repeated intermittent exposure to ketamine has rapid and long-lasting antidepressant effects, but the abuse potential has only been assessed at high doses. Furthermore, while females are more susceptible to depression and more sensitive to ketamine's antidepressant-like effects, the abuse potential for ketami...

journal_title：Psychopharmacology

authors： Wright KN,Strong CE,Addonizio MN,Brownstein NC,Kabbaj M

更新日期：2017-02-01 00:00:00

abstract：RATIONALE:Research on the effects of nicotine abstinence and nicotine replacement has not provided consistent information about the impact of replacement therapies on tobacco withdrawal and craving. OBJECTIVE:. This study investigated craving and withdrawal symptoms over a 72-h period of abstinence from cigarettes. M...

journal_title：Psychopharmacology

authors： Teneggi V,Tiffany ST,Squassante L,Milleri S,Ziviani L,Bye A

更新日期：2002-11-01 00:00:00

abstract：RATIONALE:Cotreatment with clorgyline shifts the development of sensitization to the D2/D3 dopamine receptor agonist quinpirole from locomotion to mouthing, an effect apparently unrelated to the monoamine oxidase inhibition property of clorgyline. This phenomenon was demonstrated in rats examined in small activity cham...

journal_title：Psychopharmacology

authors： Dvorkin A,Culver KE,Szechtman H

更新日期：2006-07-01 00:00:00

abstract：:The effect of pretreatment with ritanserin, a potent and selective serotonin-S2 (5-HT2) receptor antagonist, on the prolactin (PRL) response to electroconvulsive therapy (ECT) was studied in seven female patients suffering from major depressive disorder. They were given either ECT alone, or ECT after 10 or 20 mg ritan...

journal_title：Psychopharmacology

authors： Papakostas Y,Markianos M,Papadimitriou G,Stefanis C

更新日期：1990-01-01 00:00:00

abstract：:The effects of pindolol on the prolactin (PRL) and growth hormone (GH) responses to intravenous tryptophan (LTP) were studied in eight healthy male volunteers. Pindolol pretreatment (40 mg over 48 h) markedly attenuated the GH response to LTP and modestly, but significantly, reduced the LTP-induced increase in plasma ...

journal_title：Psychopharmacology

authors： Smith CE,Ware CJ,Cowen PJ

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:Recent studies using positron emission tomography (PET) have established the relationship between an intravenous dose of cocaine and the percentage occupancy of the dopamine transporter in humans, and have documented the requirement of more than 50% occupancy for perception of the "high". The present experim...

journal_title：Psychopharmacology

authors： Gatley SJ,Volkow ND,Gifford AN,Fowler JS,Dewey SL,Ding YS,Logan J

更新日期：1999-09-01 00:00:00

abstract：:The effects of naloxone on diazepam-induced release of behavior in aversive situations were investigated in rats. Naloxone (0.5 and 1 mg/kg-1) suppressed diazepam-induced eating in an unfamiliar situation and reduced (1 mg/kg-1) spontaneous food intake. Naloxone (1 mg/kg-1) canceled the increased lever pressing produc...

journal_title：Psychopharmacology

authors： Soubrié P,Jobert A,Thiebot MH

更新日期：1980-01-01 00:00:00

abstract：:7-Hydroxychlorpromazine (7-OHCPZ) has been identified and quantified in CSF from chlorpromazine (CPZ)-treated schizophrenic patients. The level of the metabolite in CSF was similar to that of CPZ. In serum the amount of 7-OHCPZ was about 30% of CPZ. The concentration of 7-OHCPZ in csf was positively and significantly ...

journal_title：Psychopharmacology

authors： Alfredsson G,Lindberg M,Sedvall G

更新日期：1982-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Blood oxygen level dependent (BOLD) contrast pharmacological magnetic resonance imaging (phMRI) is an increasingly popular technique that allows the non-invasive investigation of spatial and temporal changes in rat brain function in response to pharmacological stimulation in vivo. Rat brain BOL...

journal_title：Psychopharmacology

authors： Steward CA,Marsden CA,Prior MJ,Morris PG,Shah YB

更新日期：2005-08-01 00:00:00