Dissection of HA20, a double mutant of bacteriophage SPO1.

abstract：:Genetic variation of the more complex retroviruses in the human T-cell leukemia virus/bovine leukemia virus (HTLV/BLV) group is less than in some other retroviral genera. To test whether reverse transcription of HTLV/BLV group members is less error prone than that of members of other groups, we developed an assay for ...

journal_title：Journal of virology

authors： Mansky LM,Temin HM

更新日期：1994-01-01 00:00:00

abstract：:Superinfection exclusion is the ability of an established virus infection to interfere with infection by a second virus. In this study, we found that Huh-7.5 cells acutely infected with hepatitis C virus (HCV) genotype 2a (chimeric strain J6/JFH) and cells harboring HCV genotype 1a, 1b, or 2a full-length or subgenomic...

journal_title：Journal of virology

authors： Tscherne DM,Evans MJ,von Hahn T,Jones CT,Stamataki Z,McKeating JA,Lindenbach BD,Rice CM

更新日期：2007-04-01 00:00:00

abstract：:The p24 protein, one of the three proteins implicated in local movement of potato virus X (PVX), was expressed in transgenic tobacco plants (Nicotiana tabacum Xanthi D8 NN). Plants with the highest level of p24 accumulation exhibited a stunted and slightly chlorotic phenotype. These transgenic plants facilitate the ce...

journal_title：Journal of virology

authors： Ares X,Calamante G,Cabral S,Lodge J,Hemenway P,Beachy RN,Mentaberry A

更新日期：1998-01-01 00:00:00

abstract：:Mutants (N(-)nin) of bacteriophage lambda in which the N gene product is not required for growth on wild-type Escherichia coli do not plate on recA bacterial mutants. Secondary mutants, selected for growth on recA, lie within the immunity region to the right of gene cI and appear identical to the cro mutants of Eisen ...

journal_title：Journal of virology

authors： Court D,Campbell A

更新日期：1972-06-01 00:00:00

abstract：:Herpes simplex virus 1 (HSV-1) establishes a lifelong latent infection in host peripheral neurons, including the neurons of the trigeminal ganglia (TG). HSV-1 can reactivate from neurons to cause recurrent infection. During latency, the insulator protein CTCF occupies DNA binding sites on the HSV-1 genome, and these s...

journal_title：Journal of virology

authors： Washington SD,Edenfield SI,Lieux C,Watson ZL,Taasan SM,Dhummakupt A,Bloom DC,Neumann DM

更新日期：2018-05-14 00:00:00

abstract：:Two different proteins with high affinities for the pteridine ring of folic acid have been used to determine the location of this portion of the folate molecule in the tail plate of T4D and other T-even bacteriophage particles. The two proteins used were (i) antibody specific for folic acid and (ii) the folate-binding...

journal_title：Journal of virology

authors： Kozloff LM,Lute M,Crosby LK

更新日期：1975-12-01 00:00:00

abstract：:The XC rat cell line was found to support the replication of a strain of the Moloney murine sarcoma-leukemia virus. In growth curve experiments cytopathology was paralleled by the production of murine sarcoma virus and leukemia virus progeny having the biologic, antigenic, and biophysical properties of the infecting v...

journal_title：Journal of virology

authors： Trowbridge ST,Benyesh-Melnick M,Biswal N

更新日期：1973-01-01 00:00:00

abstract：:The primary pathophysiologic finding of the viral disease known as Korean hemorrhagic fever, the etiological agent of which is Hantaan virus (HTV), is vascular instability. To investigate whether HTV was able to infect cells derived from human vascular tissue and alter their behavior, we infected in vitro primary adul...

journal_title：Journal of virology

authors： Pensiero MN,Sharefkin JB,Dieffenbach CW,Hay J

更新日期：1992-10-01 00:00:00

abstract：:The release of the ribonucleic acid (RNA)-containing phage MS2 from Escherichia coli is accompanied by cellular lysis at 37 C, whereas at 30 C phage are released from intact cells. Chloramphenicol or rifampin prevents the release of progeny phage particles at both temperatures. Neither drug causes an immediate cessati...

journal_title：Journal of virology

authors： Engelberg H,Soudry E

更新日期：1971-09-01 00:00:00

abstract：:Herpes simplex virus 1 (HSV-1) establishes a lifelong latent infection in peripheral nerve ganglia. Periodically, the virus reactivates from this latent reservoir and is transported to the original site of infection. Strains of HSV-1 have been noted to vary greatly in their virulence and reactivation efficiencies in a...

journal_title：Journal of virology

authors： Grams TR,Edwards TG,Bloom DC

更新日期：2020-07-16 00:00:00

abstract：:While a diversity of immunogens that elicit qualitatively different cellular immune responses are being assessed in clinical human immunodeficiency virus vaccine trials, the consequences of those varied responses for viral control remain poorly understood. In the present study, we evaluated the induction of virus-spec...

journal_title：Journal of virology

authors： Sun Y,Santra S,Schmitz JE,Roederer M,Letvin NL

更新日期：2008-09-01 00:00:00

abstract：:The RNA produced in vivo from bacteriophage phiX174 DNA has been analyzed by polyacrylamide-agarose gel electrophoresis and sedimentation in dimethyl sulfoxide gradients, and the results of Hayashi and Hayashi (1970) have been confirmed and extended. An efficient procedure for recovery of RNA from gels, followed by a ...

journal_title：Journal of virology

authors： Clements JB,Sinsheimer RL

更新日期：1975-01-01 00:00:00

abstract：:Two species of basic internal proteins were found in osmotic shock supernatant solutions of bacteriophages T4B, T4D, T2H, T2L, and T6. The major species of protein isolated had a molecular weight of approximately 21,000 daltons, whereas the minor protein molecular weight was near 9,500 daltons. The two protein species...

journal_title：Journal of virology

authors： Stone KR,Cummings DJ

更新日期：1970-10-01 00:00:00

abstract：:The effect of NS1 protein on the efficiency of influenza virus mRNA translation was evaluated by determining the accumulation of nucleoprotein (NP) or M1 mRNAs in the cytoplasm of cells expressing either of these genes alone or in combination with the NS1 gene, as well as the total cell accumulation of NP or M1 protei...

journal_title：Journal of virology

authors： de la Luna S,Fortes P,Beloso A,Ortín J

更新日期：1995-04-01 00:00:00

abstract：:Human metapneumovirus (hMPV) is a leading cause of viral lower respiratory tract infection in children. The sole target of neutralizing antibodies targeting hMPV is the fusion (F) protein, a class I viral fusion protein mediating virus-cell membrane fusion. There have been several monoclonal antibodies (mAbs) isolated...

journal_title：Journal of virology

authors： Bar-Peled Y,Diaz D,Pena-Briseno A,Murray J,Huang J,Tripp RA,Mousa JJ

更新日期：2019-09-12 00:00:00

abstract：:Profiles of bacteriophage T4 early proteins resolved by a two-dimensional nonequilibrium pH gradient electrophoresis system (P. Z. O'Farrell, H. M. Goodman, and P. H. O'Farrell, Cell 12:1133--1142, 1977) are presented. Over 65 phage-induced proteins were resolved. Amber or deletion mutants were used to identify 17 pro...

journal_title：Journal of virology

authors： Cook KS,Seasholtz AF

更新日期：1982-06-01 00:00:00

abstract：:We had previously demonstrated that a cellular protein specifically interacts with the 3' end of poliovirus negative-strand RNA. We now report the identity of this protein as heterogeneous nuclear ribonucleoprotein (hnRNP) C1/C2. Formation of an RNP complex with poliovirus RNA was severely impaired by substitution of ...

journal_title：Journal of virology

authors： Brunner JE,Nguyen JH,Roehl HH,Ho TV,Swiderek KM,Semler BL

更新日期：2005-03-01 00:00:00

abstract：:CD4C/HIV(nef) transgenic (Tg) mice express Nef in CD4+ T cells and in the cells of the macrophage/monocyte/dendritic lineage, and they develop an AIDS-like disease similar to human AIDS. In these mice, Nef is constitutively expressed throughout life. To rule out the contribution of any developmental defects caused by ...

journal_title：Journal of virology

authors： Rahim MM,Chrobak P,Hu C,Hanna Z,Jolicoeur P

更新日期：2009-11-01 00:00:00

abstract：:Viral protein R (Vpr) of human immunodeficiency virus type 1 has potent karyophilic properties, but details of the mechanism by which it enters the nucleus remain to be clarified. We reported previously that two regions, located between residues 17 and 34 (alphaH1) and between residues 46 and 74 (alphaH2), are indispe...

journal_title：Journal of virology

authors： Kamata M,Nitahara-Kasahara Y,Miyamoto Y,Yoneda Y,Aida Y

更新日期：2005-03-01 00:00:00

abstract：:The multistranded and double-stranded RNAs synthesized in HeLa cells infected with rhinovirus in the presence and in the absence of actinomycin D have been characterized by polyacrylamide gel electrophoresis and hybridization studies. The replicative form is only found in infected cells treated with actinomycin D, whe...

journal_title：Journal of virology

authors： Macnaughton MR,Cooper JA,Dimmock NJ

更新日期：1976-06-01 00:00:00

abstract：UNLABELLED:The first discovered and sequenced hepatitis C virus (HCV) genome and the first in vivo infectious HCV clones originated from the HCV prototype strains HCV-1 and H77, respectively, both widely used in research of this important human pathogen. In the present study, we developed efficient infectious cell cult...

journal_title：Journal of virology

authors： Li YP,Ramirez S,Mikkelsen L,Bukh J

更新日期：2015-01-01 00:00:00

abstract：:Influenza virus infection initiates transcription of a variety of genes for cytokines such as tumor necrosis factor alpha (TNF-alpha), TNF-beta, interleukin 1 alpha, (IL-1 alpha), IL-1 beta, IL-2, IL-4, IL-6, IL-10, granulocyte macrophage colony-stimulating factor, and gamma interferon. However, the mechanism by which...

journal_title：Journal of virology

authors： Pahl HL,Baeuerle PA

更新日期：1995-03-01 00:00:00

abstract：:We present an antiviral-immunomodulatory therapeutic strategy involving the chemokine receptor antagonist Met-RANTES, which yields significant survival in the setting of an otherwise fatal respiratory virus infection. In previous work, we demonstrated that infection with the natural rodent pathogen pneumonia virus of ...

journal_title：Journal of virology

authors： Bonville CA,Lau VK,DeLeon JM,Gao JL,Easton AJ,Rosenberg HF,Domachowske JB

更新日期：2004-08-01 00:00:00

abstract：:Replication-defective vaccine vectors based on vesicular stomatitis virus (VSV) lacking its envelope glycoprotein gene (G) are highly effective in animal models. However, such ΔG vectors are difficult to grow because they require complementation with the VSV G protein. In addition, the complementing G protein induces ...

journal_title：Journal of virology

authors： Chattopadhyay A,Rose JK

更新日期：2011-03-01 00:00:00

abstract：:Defective interfering RNAs have long been thought to be a causal factor of persistent RNA virus infections. Here we describe a novel type of defective genome of lymphocytic choriomeningitis virus and the unique mechanism by which these RNAs appear to contribute to the establishment and maintenance of persistent infect...

journal_title：Journal of virology

authors： Meyer BJ,Southern PJ

更新日期：1997-09-01 00:00:00

abstract：:A receptor on YAC-1 cells, a mouse T-lymphoma cell line, bound all six serotypes of the group B coxsackieviruses (CVB). In addition, the cells produced infectious virus. Each of the CVB competed for the same receptor on YAC-1 cells. CVB3 bound relatively slowly to YAC-1 cells (k = 4 x 10(-11) min-1 cell-1), and there ...

journal_title：Journal of virology

authors： Hsu KH,Crowell RL

更新日期：1989-07-01 00:00:00

abstract：:A number of human immunodeficiency type 1 (HIV-1)-based vectors have recently been shown to transduce nondividing cells in vivo as well as in vitro. However, if these vectors are to be considered for eventual clinical use, a major consideration is to reduce the probability of unintended generation of replication-compe...

journal_title：Journal of virology

authors： Gasmi M,Glynn J,Jin MJ,Jolly DJ,Yee JK,Chen ST

更新日期：1999-03-01 00:00:00

abstract：:We have previously identified 11 epitopes located in two topologically nonoverlapping antigenic sites (A and B) and a third bridging site (C) on the human type 3 parainfluenza virus (PIV3) hemagglutinin-neuraminidase (HN) glycoprotein by using monoclonal antibodies (MAbs) which inhibit hemagglutination and virus infec...

journal_title：Journal of virology

authors： Coelingh KJ,Winter CC,Murphy BR,Rice JM,Kimball PC,Olmsted RA,Collins PL

更新日期：1986-10-01 00:00:00

abstract：:The relationship between immunosenescence and the host response to virus infection is poorly understood at the molecular level. Two different patterns of pulmonary host responses to virus were observed when gene expression profiles from severe acute respiratory syndrome coronavirus (SARS-CoV)-infected young mice that ...

journal_title：Journal of virology

authors： Baas T,Roberts A,Teal TH,Vogel L,Chen J,Tumpey TM,Katze MG,Subbarao K

更新日期：2008-10-01 00:00:00

abstract：:V3-glycan-targeting broadly neutralizing antibodies (bNAbs) are a focus of HIV-1 vaccine development. Understanding the viral dynamics that stimulate the development of these antibodies can provide insights for immunogen design. We used a deep-sequencing approach, together with neutralization phenotyping, to investiga...

journal_title：Journal of virology

authors： Anthony C,York T,Bekker V,Matten D,Selhorst P,Ferreria RC,Garrett NJ,Karim SSA,Morris L,Wood NT,Moore PL,Williamson C

更新日期：2017-08-24 00:00:00