Hantaan virus infection of human endothelial cells.

abstract：:Titers of vaccinia virus consistently increased in cultures of washed phytohemagglutinin-treated, peripheral blood leukocytes of a vaccinated adult. Concomitantly, a gradual rise occurred in the numbers of infected leukocytes, as determined by the infective center assay. Increase in viral titer was accompanied by cell...

journal_title：Journal of virology

authors： Miller G,Enders JF

更新日期：1968-08-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) utilizes clathrin-mediated endocytosis for its infectious entry into human foreskin fibroblast (HFF) cells (S. M. Akula, P. P. Naranatt, N.-S. Walia, F.-Z. Wang, B. Fegley, and B. Chandran, J. Virol. 77:7978-7990, 2003). Here, we characterized KSHV entry into primary huma...

journal_title：Journal of virology

authors： Raghu H,Sharma-Walia N,Veettil MV,Sadagopan S,Chandran B

更新日期：2009-05-01 00:00:00

abstract：:The family Anelloviridae includes human and animal torque teno viruses (TTVs) with extensive genetic diversity. The antigenic diversity among anelloviruses has never been assessed. Using torque teno sus virus (TTSuV) as a model, we describe here the first investigation of the antigenic relationships among different an...

journal_title：Journal of virology

authors： Huang YW,Harrall KK,Dryman BA,Opriessnig T,Vaughn EM,Roof MB,Meng XJ

更新日期：2012-10-01 00:00:00

abstract：:The unique short (Us) region of the pseudorabies virus (PRV) genome, which displays high transcriptional activity during the late phase of infection and has been found to code for glycoproteins, is partially deleted in the genomes of three vaccine strains (A57, Norden, and NIA-4). This deletion is located in the SalI ...

journal_title：Journal of virology

authors： Mettenleiter TC,Lukàcs N,Rziha HJ

更新日期：1985-10-01 00:00:00

abstract：:Small-t antigen of simian virus 40 renders CV-1 cells resistant to growth arrest induced by theophylline and other methylxanthines. Elevated levels of cyclic AMP are not involved in growth arrest of CV-1 cells by methylxanthines, and small-t antigen does not alter cyclic AMP levels dramatically after infection. ...

journal_title：Journal of virology

authors： Renz C,Rundell K

更新日期：1985-06-01 00:00:00

abstract：:Retroviruses are believed to induce tumors by acting as insertional mutagens that activate expression of cellular protooncogenes. Indeed, almost 90% of mouse mammary tumor virus (MMTV)-induced mammary tumors in C3H/He mice show upregulation of Int protooncogenes. We have analyzed three different MMTV variants [MMTV(C3...

journal_title：Journal of virology

authors： Hook LM,Agafonova Y,Ross SR,Turner SJ,Golovkina TV

更新日期：2000-10-01 00:00:00

abstract：:In this study, we investigated the interaction of reovirus particles with cell membranes by using a 51Cr release assay. We confirmed prior observations (J. Borsa, B. D. Morash, M. D. Sargent, T. P. Copps, P. A. Lievaart, and J. G. Szekely, J. Gen. Virol. 45:161-170, 1979) that intermediate subviral particles (ISVPs) o...

journal_title：Journal of virology

authors： Lucia-Jandris P,Hooper JW,Fields BN

更新日期：1993-09-01 00:00:00

abstract：UNLABELLED:We have shown that glycoprotein K (gK) and its interacting partner, the UL20 protein, play crucial roles in virion envelopment. Specifically, virions lacking either gK or UL20 fail to acquire an envelope, thus causing accumulation of capsids in the cytoplasm of infected cells. The herpes simplex virus 1 (HSV...

journal_title：Journal of virology

authors： Jambunathan N,Chouljenko D,Desai P,Charles AS,Subramanian R,Chouljenko VN,Kousoulas KG

更新日期：2014-06-01 00:00:00

abstract：:Adenovirus infections cause significant morbidity and mortality in immunocompromised patients, yet little is known about the immune response to adenovirus infections. We established a system for the generation of a cytotoxic immune response to adenovirus in vitro. Cytotoxic T cells (CTLs) were derived from normal dono...

journal_title：Journal of virology

authors： Smith CA,Woodruff LS,Kitchingman GR,Rooney CM

更新日期：1996-10-01 00:00:00

abstract：:Bacterial lipopolysaccharide (LPS) induces interferon (IFN) secretion and an antiviral state in murine peritoneal macrophages (PM). These cells secrete predominantly IFN-beta, as shown by neutralization assays with monoclonal antibodies. Secretion of IFN-beta is also induced in PM by IFN-gamma. LPS and IFN-gamma syner...

journal_title：Journal of virology

authors： Gessani S,Belardelli F,Pecorelli A,Puddu P,Baglioni C

更新日期：1989-06-01 00:00:00

abstract：:Polyoma virus particles were purified by equilibrium centrifugation in CsCl. Particles from three regions of the density gradient were examined for infectivity, for their ability to induce expanded pools of deoxyribonucleic acid (DNA) precursors, and for their ability to stimulate the synthesis of DNA. The most infect...

journal_title：Journal of virology

authors： Skoog L,Nordenskjöld BA,Lindberg U

更新日期：1970-07-01 00:00:00

abstract：:Given the current difficulties generating vaccine-induced neutralizing antibodies to human immunodeficiency virus (HIV), the focus of the vaccine community has shifted toward creating cytotoxic-T-lymphocyte (CTL)-based vaccines. Recent reports of CTL-based vaccine trials in macaques challenged with simian/human immuno...

journal_title：Journal of virology

authors： Vogel TU,Reynolds MR,Fuller DH,Vielhuber K,Shipley T,Fuller JT,Kunstman KJ,Sutter G,Marthas ML,Erfle V,Wolinsky SM,Wang C,Allison DB,Rud EW,Wilson N,Montefiori D,Altman JD,Watkins DI

更新日期：2003-12-01 00:00:00

abstract：:Prasinoviruses infecting unicellular green algae in the order Mamiellales (class Mamiellophyceae) are commonly found in coastal marine waters where their host species frequently abound. We tested 40 Ostreococcus tauri viruses on 13 independently isolated wild-type O. tauri strains, 4 wild-type O. lucimarinus strains, ...

journal_title：Journal of virology

authors： Clerissi C,Desdevises Y,Grimsley N

更新日期：2012-04-01 00:00:00

abstract：:Chronic viruses such as herpes simplex virus 1 (HSV-1) evade the hosts' immune system by inducing the exhaustion of antiviral T cells. In the present study, we found that exhausted HSV-specific CD8+ T cells, with elevated expression of programmed death ligand-1 (PD-1) and lymphocyte activation gene-3 (LAG-3) receptors...

journal_title：Journal of virology

authors： Roy S,Coulon PG,Prakash S,Srivastava R,Geertsema R,Dhanushkodi N,Lam C,Nguyen V,Gorospe E,Nguyen AM,Salazar S,Alomari NI,Warsi WR,BenMohamed L

更新日期：2019-08-28 00:00:00

abstract：UNLABELLED:Respiratory syncytial virus (RSV), a member of the Paramyxoviridae family of nonsegmented, negative-sense, single-stranded RNA genome viruses, is a leading cause of lower respiratory tract infections in infants, young children, and the elderly or immunocompromised. There are many open questions regarding the...

journal_title：Journal of virology

authors： Kiss G,Holl JM,Williams GM,Alonas E,Vanover D,Lifland AW,Gudheti M,Guerrero-Ferreira RC,Nair V,Yi H,Graham BS,Santangelo PJ,Wright ER

更新日期：2014-07-01 00:00:00

abstract：:Replication of the human herpesvirus Epstein-Barr virus drastically impairs cellular protein synthesis. This shutoff phenotype results from mRNA degradation upon expression of the early lytic-phase protein BGLF5. Interestingly, BGLF5 is the viral DNase, or alkaline exonuclease, homologues of which are present througho...

journal_title：Journal of virology

authors： Horst D,Burmeister WP,Boer IG,van Leeuwen D,Buisson M,Gorbalenya AE,Wiertz EJ,Ressing ME

更新日期：2012-09-01 00:00:00

abstract：:Mammalian reoviruses are internalized into cells by receptor-mediated endocytosis. Within the endocytic compartment, the viral outer capsid undergoes acid-dependent proteolysis resulting in removal of the sigma3 protein and proteolytic cleavage of the mu1/mu1C protein. Ammonium chloride (AC) is a weak base that blocks...

journal_title：Journal of virology

authors： Clark KM,Wetzel JD,Gu Y,Ebert DH,McAbee SA,Stoneman EK,Baer GS,Zhu Y,Wilson GJ,Prasad BV,Dermody TS

更新日期：2006-01-01 00:00:00

abstract：:Myeloblastosis-associated virus (MAV)-2(0), a virus which was derived from avian myeloblastosis virus and induced a high incidence of osteopetrosis, was compared with avian lymphomatosis virus 5938, a recent field isolate which induced a high incidence of lymphomatosis. The following information was obtained. (i) MAV-...

journal_title：Journal of virology

authors： Smith RE,Davids LJ,Neiman PE

更新日期：1975-01-01 00:00:00

abstract：:Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (Tfh) cells with germinal center (GC) B cells. Th1 polarization of Tfh cells is an important process shaping the success of Tfh-GC B cell interactions by influencing costimulatory and cytokine-dependent T...

journal_title：Journal of virology

authors： Verma A,Schmidt BA,Elizaldi SR,Nguyen NK,Walter KA,Beck Z,Trinh HV,Dinasarapu AR,Lakshmanappa YS,Rane NN,Matyas GR,Rao M,Shen X,Tomaras GD,LaBranche CC,Reimann KA,Foehl DH,Gach JS,Forthal DN,Kozlowski PA,Amara RR

更新日期：2020-02-28 00:00:00

abstract：:Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus that causes neurological diseases in a variety of warm-blooded animal species. There is general consensus that BDV can also infect humans, being a possible zoonosis. Although the clinical consequences of human BDV infection are still controversial,...

journal_title：Journal of virology

authors： Bajramovic JJ,Syan S,Brahic M,de la Torre JC,Gonzalez-Dunia D

更新日期：2002-06-01 00:00:00

abstract：:The degree of genetic heterogeneity of DNA virus populations in nature and its consequences for disease control are virtually unknown. The parvovirus minute virus of mice (MVMi) was used here to investigate (i) the frequency of antibody-escape mutants in populations of a DNA virus and (ii) the ability of a DNA virus t...

journal_title：Journal of virology

authors： López-Bueno A,Mateu MG,Almendral JM

更新日期：2003-02-01 00:00:00

abstract：:Whether a genetic informational nucleic acid is required for the infectivity of transmissible spongiform encephalopathies is central to the debate about the infectious agent. Here we report that an infectious prion formed with bacterially expressed recombinant prion protein plus synthetic polyriboadenylic acid and syn...

journal_title：Journal of virology

authors： Wang F,Zhang Z,Wang X,Li J,Zha L,Yuan CG,Weissmann C,Ma J

更新日期：2012-02-01 00:00:00

abstract：:Recent studies have explored the chromatin structures associated with the herpes simplex virus type 1 (HSV-1) genome during latency, particularly with regard to specific histone tail modifications such as acetylation and dimethylation. The objective of our present study was to develop a rapid systemic method of in viv...

journal_title：Journal of virology

authors： Neumann DM,Bhattacharjee PS,Hill JM

更新日期：2007-06-01 00:00:00

abstract：:Utilization of internal ribosome entry segment (IRES) structures in the 5' noncoding region (5'NCR) of picornavirus RNAs for initiation of translation requires a number of host cell factors whose distribution may vary in different cells and whose requirement may vary for different picornaviruses. We have examined the ...

journal_title：Journal of virology

authors： Graff J,Cha J,Blyn LB,Ehrenfeld E

更新日期：1998-12-01 00:00:00

abstract：:The outcome of a viral infection is regulated in part by the complex coordination of viral and host interactions that compete for the control and optimization of virus replication. Severe acute respiratory syndrome coronavirus (SARS-CoV) intimately engages and regulates the host innate immune responses during infectio...

journal_title：Journal of virology

authors： Frieman M,Ratia K,Johnston RE,Mesecar AD,Baric RS

更新日期：2009-07-01 00:00:00

abstract：:We have developed a complementation assay, using transiently transfected COS cells, to facilitate a molecular analysis of the herpes simplex virus type 1 glycoprotein gH. When infected by a gH-null syncytial virus, COS cells expressing wild-type gH generate infectious progeny virions and form a syncytium with neighbor...

journal_title：Journal of virology

authors： Wilson DW,Davis-Poynter N,Minson AC

更新日期：1994-11-01 00:00:00

abstract：:Tumor progression locus 2 (TPL2) is a serine/threonine kinase that belongs to the mitogen-activated protein 3 kinase (MAP3K) family, and it plays an important role in pathogen infection. The trimer complex of TPL2, p105, and ABIN2 is essential for maintenance of TPL2 steady-state levels and host cell response to patho...

journal_title：Journal of virology

authors： Zhang K,Yan M,Hao J,Shen C,Zhu Z,Zhang D,Hou J,Xu G,Li D,Zheng H,Liu X

更新日期：2020-12-23 00:00:00

abstract：:When ts7, a temperature-sensitive (ts) mutant of influenza B/Kanagawa/73 virus, infected MDCK cells at the nonpermissive temperature (37.5 degrees C), infectious virus was produced at very low levels compared with the yield at the permissive temperature (32 degrees C) and hemagglutinating activity and enzymatic activi...

journal_title：Journal of virology

authors： Yamamoto-Goshima F,Maeno K,Morishita T,Ueda M,Fujita Y,Nakajima K,Yoshii S

更新日期：1994-02-01 00:00:00

abstract：:Bacteriophage CL31 was isolated on a Corynebacterium lilium strain. Out of 30 strains tested, only CL31 was able to form plaques on Corynebacterium glutamicum ATCC 13287, Brevibacterium lactofermentum ATCC 21086, and Arthrobacter sp. strain SI55, but at a very low frequency. This phage belongs to group B of Bradley's ...

journal_title：Journal of virology

authors： Trautwetter A,Blanco C,Sicard AM

更新日期：1987-05-01 00:00:00

abstract：:The adenovirus major late transcription unit (MLTU) encodes five families of mRNAs, L1 to L5, each distinguished by a unique poly(A) site. Use of the promoter-proximal L1 poly(A) site predominates during early infection, whereas poly(A) site choice shifts to the promoter-distal sites during late infection. A mini-MLTU...

journal_title：Journal of virology

authors： Gilmartin GM,Hung SL,DeZazzo JD,Fleming ES,Imperiale MJ

更新日期：1996-03-01 00:00:00