Lupus anticoagulant associated with specific inhibition of factor VII in a patient with AIDS.

abstract：:In today's environment, many laboratories and pathology practices are challenged to maintain or increase their quality while simultaneously lowering their overall costs. The cost of improving specimen processes is related to quality, and we demonstrate that actual costs can be reduced by designing "quality at the sour...

journal_title：American journal of clinical pathology

authors： Carlson RO,Amirahmadi F,Hernandez JS

更新日期：2012-09-01 00:00:00

abstract：:Oxidant-antioxidant balance is known to regulate growth factors and invasion of tumor cells. Manganese superoxide dismutase (MnSOD), copper zinc SOD (CuZnSOD), and extracellular SOD (ECSOD), the first-line antioxidant defenses, were studied in lung carcinomas by immunohistochemical analysis (n = 139, 56, and 37, respe...

journal_title：American journal of clinical pathology

authors： Svensk AM,Soini Y,Pääkkö P,Hiravikoski P,Kinnula VL

更新日期：2004-09-01 00:00:00

abstract：:Breast cancer is the result of a multistage carcinogenic process. Initiation, promotion, dependency and autonomy make up a sequence of experimentally distinguishable phases of this process. Progression--the transition from dependency on hormonal support to autonomy--is demonstrable clinically. High-affinity saturatabl...

journal_title：American journal of clinical pathology

authors： Brennan MJ

更新日期：1975-12-01 00:00:00

abstract：:Thrombocytosis may reflect a primary myeloproliferative disorder or be a secondary reaction to other pathologic processes. Patients with persistent unexplained thrombocytosis meeting criteria of primary thrombocythemia had elevated levels of serum lactic dehydrogenase, whereas comparable patients with secondary thromb...

journal_title：American journal of clinical pathology

authors： Budman DR,Lackner H,Berczeller P,Silber R

更新日期：1981-06-01 00:00:00

abstract：:Serrated adenomas are the precursors of at least 5.8% of colorectal cancers; otherwise little is known of their clinical significance in comparison with conventional adenomas and hyperplastic polyps. We compared the risk of metachronous lesions in colorectal serrated adenomas, conventional adenomas, and hyperplastic p...

journal_title：American journal of clinical pathology

authors： Lazarus R,Junttila OE,Karttunen TJ,Mäkinen MJ

更新日期：2005-03-01 00:00:00

abstract：:The May-Hegglin anomaly is one of the rare forms of heriditary thrombocytopenia. Since fewer than 100 cases of May-Hegglin anomaly have been described to date, major controversies regarding the adequacy of hemostasis in vivo and abnormalities of platelet function in vitro continue to prevail. This report describes the...

journal_title：American journal of clinical pathology

authors： Hamilton RW,Shaikh BS,Ottie JN,Storch AE,Saleem A,White JG

更新日期：1980-11-01 00:00:00

abstract：:The results from fetal-maternal hemorrhage (FMH) detection and quantitation external quality assessment surveys conducted in Ontario indicate that the rosette test had a sensitivity and specificity for an FMH of more than 10 mL of 1.0 and 0.75, respectively, compared with 0.96 and 0.92, respectively, for acid elution....

journal_title：American journal of clinical pathology

authors： Lafferty JD,Raby A,Crawford L,Linkins LA,Richardson H,Crowther M

更新日期：2003-01-01 00:00:00

abstract：:Hematogones (HGs) comprise a B-lineage lymphoid precursor cell population in the bone marrow (BM) that may simulate acute lymphoblastic leukemia or lymphoma. Increased numbers of HGs have been noted in children, but few reports describe their occurrence in adults. We identified 13 adult patients with significant numbe...

journal_title：American journal of clinical pathology

authors： Davis RE,Longacre TA,Cornbleet PJ

更新日期：1994-08-01 00:00:00

abstract：:Quantitative measurements of constituent concentrations of Survey specimens are generally recorded to the nearest integer or to the nearest tenth. Questions have arisen as to whether this degree of rounding of measurements is appropriate when available laboratory equipment can determine results more precisely. Statist...

journal_title：American journal of clinical pathology

authors： Williams GW,Schork MA

更新日期：1976-07-01 00:00:00

abstract：:During a 14-year period (1959-1972), 3,600 endometrial suction biopsies were performed in the office for specific indications in selected patients. Three hundred seventy-seven biopsies (10.5%) revealed abnormal findings. Of these, 233 showed endometritis, 96 associated with necrotic decidual or placental tissue, or bo...

journal_title：American journal of clinical pathology

authors： Baitlon D,Hadley JO

更新日期：1975-01-01 00:00:00

abstract：:Micropapillary lung adenocarcinoma (MPA) has been reported as an aggressive variant of adenocarcinoma, frequently manifesting at high stage with a poor prognosis. We analyzed the clinical and molecular profile of 15 primary MPAs for K-ras, EGFR, and BRAF mutations and performed fluorescence in situ hybridization for E...

journal_title：American journal of clinical pathology

authors： De Oliveira Duarte Achcar R,Nikiforova MN,Yousem SA

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:The 2014 Bethesda System (TBS 2014) guidelines for reporting cervical cytology revised the age for reporting benign endometrial cells (BECs) from 40 years or older to age 45 years or older. We evaluated this change and further investigated if extending the reporting age to 50 years or older may be acceptable...

journal_title：American journal of clinical pathology

authors： Hernandez A,Schatz-Siemers N,Zhou F,Brandler TC,Negron R,Modi L,Elgert PA,Simsir A

更新日期：2020-08-05 00:00:00

abstract：:Thirty-five consecutive renal biopsy specimens were evaluated by light histology using paraffin and glycol methacrylate embedding. The clarity of the renal structures was found to be much better, and the renal lesions better defined, using glycol methyacrylate embedding. ...

journal_title：American journal of clinical pathology

authors： Agodoa LC,Striker GE,Chi E

更新日期：1975-11-01 00:00:00

abstract：:Our purpose was to evaluate the clinical, histologic, and histochemical staining characteristics of intestinal metaplasia (IM) at an endoscopically normal-appearing esophagogastric junction (IM-EGJ) compared with IM in a columnar-lined esophagus (IM-CLE). A prospective study included 253 patients referred for elective...

journal_title：American journal of clinical pathology

authors： van Sandick JW,van Lanschot JB,van Felius L,Haringsma J,Tytgat GN,Dekker W,Drillenburg P,Offerhaus GJ,ten Kate FJ

更新日期：2002-01-01 00:00:00

abstract：:By application of combined structural and functional analyses, most lymphoid neoplasms may be categorized as of T- or B-cell origin. T lymphocyte neoplasms include types of acute and chronic lymphocytic leukemias, certain cutaneous and node-based lymphomas, and lymphomas of thymocytes (convoluted lymphocytic lymphomas...

journal_title：American journal of clinical pathology

authors： Collins RD,Waldron JA,Glick AD

更新日期：1979-10-01 00:00:00

abstract：:Subsequent to recent disclosures that low serum vitamin B12 results can appear normal using many of the current radioassay methods because of the presence of cobalamin (vitamin B12) analogues in human serum, a number of radioassay kits have become available with modified intrinsic factor preparations and claims of mea...

journal_title：American journal of clinical pathology

authors： LeFebvre RJ,Virji AS,Mertens BF

更新日期：1980-08-01 00:00:00

abstract：:We undertook a retrospective analysis of colonic spirochetosis in 14 cases: females, 3; males, 11; children, 4; adults, 10. Two men had HIV infections. All children and both HIV-infected men had abdominal complaints, diarrhea, or both. Most other adults underwent colonoscopy for polyp screening (n = 4) or follow-up of...

journal_title：American journal of clinical pathology

authors： Koteish A,Kannangai R,Abraham SC,Torbenson M

更新日期：2003-12-01 00:00:00

abstract：:To facilitate the differential diagnosis of poorly differentiated metastatic carcinomas of unknown primary site, we evaluated p63 and cytokeratin (CK) 5/6 as immunohistochemical markers for squamous cell carcinomas. The study cases were as follows: squamous cell carcinoma of the lungs, head/neck, esophagus, cervix ute...

journal_title：American journal of clinical pathology

authors： Kaufmann O,Fietze E,Mengs J,Dietel M

更新日期：2001-12-01 00:00:00

abstract：:Soft-agar culture of transitional cell carcinoma colonies from urine, bladder irrigation fluid, and transurethral resection solid tumor specimens demonstrate generally better growth of tumor cell colonies from urine than from irrigation fluid. Growth of tumor colonies from urine was adequate to evaluate presence of tu...

journal_title：American journal of clinical pathology

authors： Kirkels WJ,Pelgrim OE,Debruyne FM,Vooijs GP,Herman CJ

更新日期：1982-11-01 00:00:00

abstract：:We describe 35 peripheral lymph nodes classified as mantle cell/marginal zone B-cell hyperplasia with clear cells using morphologic and immunologic findings. For the purpose of this study, we obtained clinical follow-up information and performed immunoglobulin gene rearrangement studies on paraffin sections by polymer...

journal_title：American journal of clinical pathology

authors： Hunt JP,Chan JA,Samoszuk M,Brynes RK,Hernandez AM,Bass R,Weisenburger DD,Müller-Hermelink K,Nathwani BN

更新日期：2001-10-01 00:00:00

abstract：:We describe a method of spectrophotometric detection of BCR/ABL chimeric sequences amplified by multiplex reverse transcriptase-polymerase chain reaction (RT-PCR), enabling the use of archival hematologic slides as RNA sources. Multiplex PCR amplified b3a2, b2a2, and e1a2 break points of the BCR/ABL translocation and ...

journal_title：American journal of clinical pathology

authors： Attadia V,Alosi M,Improta S,Zagonel V,Martinazzo G,Carbone A,Pinto A

更新日期：1997-10-01 00:00:00

abstract：:We compared prothrombin times (PTs) and international normalized ratios (INRs) for blood samples drawn into plastic vs glass collection tubes. We collected 60 venous blood samples into 4.5-mL glass and 2 plastic tubes (2.7 and 3.5 mL). An additional 153 samples, including 63 from warfarin-anticoagulated patients, were...

journal_title：American journal of clinical pathology

authors： Fiebig EW,Etzell JE,Ng VL

更新日期：2005-12-01 00:00:00

abstract：:A 28-month-old girl, whose parents are first cousins, was hospitalized following a series of severe infections. Results of functional granulocytic tests permitted the diagnosis of chronic granulomatous disease (lack of nitroblue tetrazolium dye reduction, impaired bactericidal activity for Staphylococcus aureus but no...

journal_title：American journal of clinical pathology

authors： Corberand J,De Larrard B,Vergnes H,Carrière JP

更新日期：1978-08-01 00:00:00

abstract：:The API-20 Enteric Strip has been proposed to have the capacity to differentiate the nonfermentative gram-negative bacilli. This multitest strip serves as the basis of an evolving system, which first provided a Register, then a Selector, and more recently a computer Index. Twenty-three strains of Pseudomonas aeruginos...

journal_title：American journal of clinical pathology

authors： Morris MJ,Young VM,Moody MR

更新日期：1978-01-01 00:00:00

abstract：:Primary malignant germ cell tumors of the mediastinum are extremely rare among females. This report describes such a tumor arising in the mediastinum of a 26-year-old woman and correlates immunohistochemical studies of the neoplasm with serum tumor markers. Microscopic examination of the tumor revealed an embryonal ca...

journal_title：American journal of clinical pathology

authors： Sandhaus L,Strom RL,Mukai K

更新日期：1981-04-01 00:00:00

abstract：OBJECTIVES:To investigate metastasis associated in colon cancer 1 (MACC1) and MET expression in colorectal adenoma, Tis, early-stage invasive (T1 and T2), and advanced adenocarcinoma with liver metastasis using immunohistochemistry. METHODS:Ninety-three paraffin-embedded colorectal tumor specimens were immunohistochem...

journal_title：American journal of clinical pathology

authors： Ren B,Zakharov V,Yang Q,McMahon L,Yu J,Cao W

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:Certain laboratory tests are critical for patient care and must be communicated rapidly. Professional societies have developed guidelines for reporting of "critical values" and significant or unexpected surgical pathology findings. Urgent diagnoses requiring rapid reporting include new or unexpected diagnose...

journal_title：American journal of clinical pathology

authors： Layfield LJ,Schnabel JL

更新日期：2014-12-01 00:00:00

abstract：Objectives:Diagnosis of B-cell acute lymphoblastic leukemia (B-ALL) requires immunophenotypic evidence of B-lineage and absence of specific myeloid or T-lineage markers. Rare cases of otherwise typical B-ALL express myeloperoxidase (MPO) detectable by flow cytometry with an absence of other myeloid markers, but the cli...

journal_title：American journal of clinical pathology

authors： Oberley MJ,Li S,Orgel E,Phei Wee C,Hagiya A,O'Gorman MRG

更新日期：2017-04-01 00:00:00

abstract：:Worldwide, infection with hepatitis viruses remains a major clinical and public heath concern. The laboratory is an integral part of the diagnosis of these infections since many of the manifestations are nonspecific, and the various hepatitis viruses show overlapping symptomatology. In this article, we discuss the lab...

journal_title：American journal of clinical pathology

authors： Harris KR,Dighe AS

更新日期：2002-12-01 00:00:00

abstract：:During a 6-month period at Walter Reed Army Hospital the monthly attack rate of Staphylococcus aureus bacteremia increased to 3.8 +/- 0.5 (mean +/- SEM) from 2.5 +/- 0.2 cases per 1,000 dispositions for the previous 48 months (P less than 0.05). A predominant phage pattern, designated S, was found in 12 (39%) of 31 ba...

journal_title：American journal of clinical pathology

authors： Cross AS,Zierdt CH,Roup B,Almazan R,Swan JC

更新日期：1983-05-01 00:00:00