Optimisation of field flatness and depth-dose for therapy electron beams.

abstract：:In electron beam dosimetry using parallel-plate chambers solid phantoms are sometimes necessary. To obtain the dose to water from the ionization obtained in the solid phantom, fluence correction factors and perturbation factors have to be applied. In this study fluence factors in a perturbation free geometry have been...

journal_title：Physics in medicine and biology

authors： Nilsson B,Montelius A,Andreo P,Johansson J

更新日期：1997-11-01 00:00:00

abstract：:This study presents a theoretical approach to the dosimetry for small and non-equilibrium radiation fields. We applied the newly developed VMCBC algorithm to the dosimetry for megavoltage photon beams using Monte Carlo techniques. The approach assumes that a Monte Carlo simulated beam can be calibrated per incident pa...

journal_title：Physics in medicine and biology

authors： Ding GX,Duggan DM,Coffey CW

更新日期：2008-07-07 00:00:00

abstract：:The geometry of a permanent prostate implant varies over time. Seeds can migrate and edema of the prostate affects the position of seeds. Seed movements directly influence dosimetry which relates to treatment quality. We present a method that tracks all individual seeds over time allowing quantification of seed moveme...

journal_title：Physics in medicine and biology

authors： Westendorp H,Nuver TT,Moerland MA,Minken AW

更新日期：2015-10-21 00:00:00

abstract：:Radiation therapy treatment planning requires an incorporation of uncertainties in order to guarantee an adequate irradiation of the tumor volumes. In current clinical practice, uncertainties are accounted for implicitly with an expansion of the target volume according to generic margin recipes. Alternatively, it is p...

journal_title：Physics in medicine and biology

authors： Mescher H,Ulrich S,Bangert M

更新日期：2017-09-05 00:00:00

abstract：:The trend towards conformal, intensity modulated radiotherapy treatments has established the need for a true integrating dosimeter. In traditional radiotherapy, radiographic film dosimetry is commonly used. The accuracy and reproducibility of film optical density as an indicator of dose is influenced by several variab...

journal_title：Physics in medicine and biology

authors： Suchowerska N,Hoban P,Butson M,Davison A,Metcalfe P

更新日期：2001-05-01 00:00:00

abstract：:A comparative study was performed to reveal differences and relative figures of merit of seven different calculation algorithms for photon beams when applied to inhomogeneous media. The following algorithms were investigated: Varian Eclipse: the anisotropic analytical algorithm, and the pencil beam with modified Batho...

journal_title：Physics in medicine and biology

authors： Fogliata A,Vanetti E,Albers D,Brink C,Clivio A,Knöös T,Nicolini G,Cozzi L

更新日期：2007-03-07 00:00:00

abstract：:To calculate photon spectra for a 10 MV x-ray beam emitted by a medical linear accelerator, we performed numerical analysis using the aluminium transmission data obtained along the central axis of the beam under the narrow beam condition corresponding to a 3x3 cm2 field at a 100 cm distance from the source. We used th...

journal_title：Physics in medicine and biology

authors： Shimozato T,Tabushi K,Kitoh S,Shiota Y,Hirayama C,Suzuki S

更新日期：2007-01-21 00:00:00

abstract：:Nuclear emulsions of the Ilford K series, exposed to X-rays from 15 to 150 kVp and systematically underdeveloped, exhibit supralinear blackness--exposure curves ranging from 1- to 4-hit in character, and whose shape is the same at all excitation voltages. Processing can be so adjusted that the curve shape is well repr...

journal_title：Physics in medicine and biology

authors： Katz R,Pennington EC

更新日期：1978-11-01 00:00:00

abstract：:It has been reported that acoustic waves are generated when a high-energy pulsed proton beam is deposited in a small volume within tissue. One possible application of proton-induced acoustics is to get real-time feedback for intra-treatment adjustments by monitoring such acoustic waves. A high spatial resolution in ul...

journal_title：Physics in medicine and biology

authors： Kipergil EA,Erkol H,Kaya S,Gulsen G,Unlu MB

更新日期：2017-06-21 00:00:00

abstract：:Iterative tomographic reconstruction has been established as a viable alternative for data analysis in phase-sensitive x-ray imaging based on the edge-illumination principle. However, previously published approaches did not account for drifts of optical elements during a scan, which can lead to artefacts. Up to now, t...

journal_title：Physics in medicine and biology

authors： Modregger P,Meganck J,Hagen CK,Massimi L,Olivo A,Endrizzi M

更新日期：2019-10-10 00:00:00

abstract：:Conventional molecular assessment of tissue through histology, if adapted to fresh thicker samples, has the potential to enhance cancer detection in surgical margins and monitoring of 3D cell culture molecular environments. However, in thicker samples, substantial background staining is common despite repeated rinsing...

journal_title：Physics in medicine and biology

authors： Xu X,Wang Y,Xiang J,Liu JTC,Tichauer KM

更新日期：2017-06-21 00:00:00

abstract：:In this study we present a three-dimensional (3D) reconstruction algorithm for magneto-acoustic tomography with magnetic induction (MAT-MI) based on the characteristics of the ultrasound transducer. The algorithm is investigated to solve the blur problem of the MAT-MI acoustic source image, which is caused by the ultr...

journal_title：Physics in medicine and biology

authors： Ma R,Zhou X,Zhang S,Yin T,Liu Z

更新日期：2016-12-21 00:00:00

abstract：:A technique is described for examining the mode of operation of radiation detectors and estimating the losses and gains caused by random summing effects in spectra acquired at high counting rates. The technique is applied to estimating the errors caused by random summing when measuring the amounts of carbon and nitrog...

journal_title：Physics in medicine and biology

authors： Yankuba S,Oldroyd B,Metcalfe SC,Godfrey JE,Oxby CB

更新日期：1989-08-01 00:00:00

abstract：:The dielectric properties of glycerol, propylene glycol, ethylene glycol and dimethyl sulphoxide have been measured in various aqueous concentrations generally sufficient to allow supercooling rather than freezing. The temperature range investigated is from -80 degrees C to +20 degrees C and the frequency range is 100...

journal_title：Physics in medicine and biology

authors： Michelson SC,Evans S

更新日期：1996-10-01 00:00:00

abstract：:This study aims to develop a computer-aided diagnosis (CADx) scheme for classification between malignant and benign lung nodules, and also assess whether CADx performance changes in detecting nodules associated with early and advanced stage lung cancer. The study involves 243 biopsy-confirmed pulmonary nodules. Among ...

journal_title：Physics in medicine and biology

authors： Gong J,Liu JY,Sun XW,Zheng B,Nie SD

更新日期：2018-02-05 00:00:00

abstract：:The usefulness of a direct detection scheme of the second harmonic (2h) overmodulated signal from irradiated alanine in EPR dosimetry was studied. For this purpose, a group of DL-alanine/paraffin cylindrical pellets was produced. The dosimeters were irradiated with a 60Co radiotherapy gamma source with doses of 0.05, ...

journal_title：Physics in medicine and biology

authors： Chen F,Graeff CF,Baffa O

更新日期：2002-04-21 00:00:00

abstract：:Charge-coupled devices (CCDs) coupled to scintillation crystals can be used for high-resolution imaging with x-rays and gamma rays. When the CCD images can be read out fast enough, the energy and interaction position of individual gamma quanta can be estimated by a real-time image analysis of the scintillation light f...

journal_title：Physics in medicine and biology

authors： Heemskerk JW,Westra AH,Linotte PM,Ligtvoet KM,Zbijewski W,Beekman FJ

更新日期：2007-04-21 00:00:00

abstract：:Monte Carlo simulation techniques are applied to track the annihilation photons from positron decay, and store the photon histories. Reasonably realistic models of the isotope distribution in the brain and heart during typical PET studies, as well as the traditional phantoms used for measuring PET scanner performance ...

journal_title：Physics in medicine and biology

authors： Thompson CJ,Moreno-Cantu J,Picard Y

更新日期：1992-03-01 00:00:00

abstract：:Segmented attenuation correction is now a widely accepted technique to reduce noise propagation from transmission scanning in positron emission tomography (PET). In this paper, we present a new method for segmenting transmission images in whole-body scanning. This reduces the noise in the correction maps while still c...

journal_title：Physics in medicine and biology

authors： Zaidi H,Diaz-Gomez M,Boudraa A,Slosman DO

更新日期：2002-04-07 00:00:00

abstract：:The theory of task-based assessment of image quality is reviewed in the context of imaging with ionizing radiation, and objective figures of merit (FOMs) for image quality are summarized. The variation of the FOMs with the task, the observer and especially with the mean number of photons recorded in the image is discu...

journal_title：Physics in medicine and biology

authors： Barrett HH,Myers KJ,Hoeschen C,Kupinski MA,Little MP

更新日期：2015-01-21 00:00:00

abstract：:While megavoltage cone-beam computed tomography (CBCT) using an electronic portal imaging device (EPID) provides many advantages over kilovoltage (kV) CBCT, clinical adoption is limited by its high doses. Multi-layer imager (MLI) EPIDs increase DQE(0) while maintaining high resolution. However, even well-designed, hig...

journal_title：Physics in medicine and biology

authors： Hu YH,Rottmann J,Fueglistaller R,Myronakis M,Wang A,Huber P,Shedlock D,Morf D,Baturin P,Star-Lack J,Berbeco R

更新日期：2018-01-30 00:00:00

abstract：:The aim of this study was to investigate the utility of consistency metrics, such as inverse consistency, in contour-based deformable registration error analysis. Four images were acquired of the same phantom that has experienced varying levels of deformation. The deformations were simulated with deformable image regi...

journal_title：Physics in medicine and biology

authors： Bender ET,Tomé WA

更新日期：2009-09-21 00:00:00

abstract：:A method will be described for determining the centre of rotation of a mechanically scanned reflection ultrasound computed tomography system. It is based on the principle of obtaining opposing images of a test object containing many point targets. The method is automatic in the sense that the centre of rotation is cal...

journal_title：Physics in medicine and biology

authors： Jago JR

更新日期：1994-12-01 00:00:00

abstract：:Distributions of linear pathlength measurements have been utilized in skeletal dosimetry of internally emitted short-range particles for over 30 years. This work reviews the methods for coupling these distributions to range-energy data. A revised methodology is presented for handling the insertion of the additional do...

journal_title：Physics in medicine and biology

authors： Jokisch DW,Rajon DA,Patton PW,Bolch WE

更新日期：2011-05-07 00:00:00

abstract：:Using conventional scintillation detection, the fundamental limit in positron emission tomography (PET) time resolution is strongly dependent on the inherent temporal variances generated during the scintillation process, yielding an intrinsic physical limit for the coincidence time resolution of around 100 ps. On the ...

journal_title：Physics in medicine and biology

authors： Tao L,Daghighian HM,Levin CS

更新日期：2016-11-07 00:00:00

abstract：:We show how the spectral imaging framework should be modified to account for a high fraction of Compton interactions in low Z detector materials such as silicon. Using this framework, where deposited energies differ from actual photon energies, we compare the performance of a silicon strip detector, including the infl...

journal_title：Physics in medicine and biology

authors： Bornefalk H,Danielsson M

更新日期：2010-04-07 00:00:00

abstract：:The temperature sensitivities of absorption and reduced scattering coefficients in the range 700-1000 nm are determined for the liquid phantom Intralipid using spatially resolved continuous wave measurements. The measurements were conducted on a 10 L heated volume of 1% Intralipid subjected to a 40-30 degrees C coolin...

journal_title：Physics in medicine and biology

authors： McGlone VA,Martinsen P,Künnemeyer R,Jordan B,Cletus B

更新日期：2007-05-07 00:00:00

abstract：:In a previous paper, we described quality assurance procedures for Hi-Art helical tomotherapy machines. Here, we develop further some ideas discussed briefly in that paper. Simple helically generated dose distributions are modelled, and relationships between these dose distributions and underlying characteristics of H...

journal_title：Physics in medicine and biology

authors： Fenwick JD,Tomé WA,Kissick MW,Mackie TR

更新日期：2005-04-07 00:00:00

abstract：:Silicon photomultipliers (SiPMs) are widely used in positron emission tomography (PET), however, SiPMs from different vendors vary in their performance characteristics. In addition, the specifications provided by the manufacturers are measured under different operating conditions and using different test setups, makin...

journal_title：Physics in medicine and biology

authors： Du J,Bai X,Cherry SR

更新日期：2019-08-07 00:00:00

abstract：:The goal of this study was to determine the quantitative accuracy of our OSEM-APDI reconstruction method based on SPECT/CT imaging for Tc-99m, In-111, I-123, and I-131 isotopes. Phantom studies were performed on a SPECT/low-dose multislice CT system (Infinia-Hawkeye-4 slice, GE Healthcare) using clinical acquisition p...

journal_title：Physics in medicine and biology

authors： Shcherbinin S,Celler A,Belhocine T,Vanderwerf R,Driedger A

更新日期：2008-09-07 00:00:00