Calculation of 10 MV x-ray spectra emitted by a medical linear accelerator using the BFGS quasi-Newton method.

abstract：:The in-phantom calibration method for radiotherapy kilovoltage x-ray beams requires ionization chamber correction factors. The overall ionization chamber correction factor accounts for changes in the chamber response due to the displacement of water by the chamber cavity and wall, the presence of the stem and the chan...

journal_title：Physics in medicine and biology

authors： Bancheri J,Ketelhut S,Büermann L,Seuntjens J

更新日期：2020-05-11 00:00:00

abstract：:Accurate real-time prediction of respiratory motion is desirable for effective motion management in radiotherapy for lung tumor targets. Recently, nonparametric methods have been developed and their efficacy in predicting one-dimensional respiratory-type motion has been demonstrated. To exploit the correlation among v...

journal_title：Physics in medicine and biology

authors： Ruan D,Keall P

更新日期：2010-06-07 00:00:00

abstract：:The potential of the variable-aperture collimator (VAC) in intensity-modulated radiation therapy (IMRT) has been evaluated by comparing its performance with that of the multi-leaf collimator (MLC). This comparison used a decomposition algorithm to find the series of collimator segments that would treat a given intensi...

journal_title：Physics in medicine and biology

authors： Anderson JW,Symonds-Tayler R,Hartmann G,Echner G,Lang C,Schlegel W,Webb S

更新日期：2006-04-07 00:00:00

abstract：:A micro-multileaf collimator (microMLC) for stereotactic radiosurgery is used for determination of the spatial intensity distribution of the photon source of a linear accelerator. The method is based on grid field dose measurements using film dosimetry and is easy to perform. Since the microMLC does not allow 'direct'...

journal_title：Physics in medicine and biology

authors： Treuer H,Hoevels M,Luyken K,Hunsche S,Kocher M,Müller RP,Sturm V

更新日期：2003-08-07 00:00:00

abstract：:Positron range impairs resolution in PET imaging, especially for high-energy emitters and for small-animal PET. De-blurring in image reconstruction is possible if the blurring distribution is known. Furthermore, the percentage of annihilation events within a given distance from the point of positron emission is releva...

journal_title：Physics in medicine and biology

authors： Jødal L,Le Loirec C,Champion C

更新日期：2012-06-21 00:00:00

abstract：:The dosimetric measurement and modeling of small radiation treatment fields (<2 × 2 cm2) are difficult to perform and prone to error. Measurements of small fields are often adversely influenced by the properties of the detectors used to make them. The dosimetric properties of small fields have been difficult to accura...

journal_title：Physics in medicine and biology

authors： Hundertmark B,Sterpin E,Mackie T

更新日期：2011-06-21 00:00:00

abstract：:We couple standardized low-resolution electromagnetic tomography, an inverse solution for electroencephalography (EEG) and the common spatial pattern, which is here conceived as a data-driven beamformer, to classify the benchmark BCI (brain-computer interface) competition 2003, data set IV. The data set is from an exp...

journal_title：Physics in medicine and biology

authors： Congedo M,Lotte F,Lécuyer A

更新日期：2006-04-21 00:00:00

abstract：:Modern Monte Carlo codes allow for the calculation of ion chamber specific beam quality correction factors k(Q), which are needed for dosimetry in radiotherapy. While statistical (type A) uncertainties of the calculated data can be minimized sufficiently, the influence of systematic (type B) uncertainties is mostly un...

journal_title：Physics in medicine and biology

authors： Wulff J,Heverhagen JT,Zink K,Kawrakow I

更新日期：2010-08-21 00:00:00

abstract：:The characteristics of an Elekta Precise treatment machine with a gating interface were investigated. Three detectors were used: a Farmer ionization chamber, a MatriXX ionization chamber array and an in-house, single pulse-measurement ionization chamber (IVC). Measurements were made of dosimetric accuracy, flatness an...

journal_title：Physics in medicine and biology

authors： Evans PM,Symonds-Tayler JR,Colgan R,Hugo GD,Letts N,Sandin C

更新日期：2010-04-21 00:00:00

abstract：:A clinical trial named PROMETHEUS is currently ongoing for inoperable hepatocellular carcinoma (HCC) at the Heidelberg Ion Beam Therapy Center (HIT, Germany). In this framework, 4D PET-CT datasets are acquired shortly after the therapeutic treatment to compare the irradiation induced PET image with a Monte Carlo PET p...

journal_title：Physics in medicine and biology

authors： Gianoli C,Kurz C,Riboldi M,Bauer J,Fontana G,Baroni G,Debus J,Parodi K

更新日期：2016-06-07 00:00:00

abstract：:Radiotherapy and particle therapy treatment planning require accurate knowledge of the electron density and elemental composition of the tissues in the beam path to predict the local dose deposition. We describe a method for the analysis of dual energy computed tomography (DECT) images that provides the electron densi...

journal_title：Physics in medicine and biology

authors： van Abbema JK,van Goethem MJ,Greuter MJ,van der Schaaf A,Brandenburg S,van der Graaf ER

更新日期：2015-05-07 00:00:00

abstract：:The enormous advances in the understanding of human anatomy, physiology and pathology in recent decades have led to ever-improving methods of disease prevention, diagnosis and treatment. Many of these achievements have been enabled, at least in part, by advances in ionizing radiation detectors. Radiology has been tran...

journal_title：Physics in medicine and biology

authors： Seco J,Clasie B,Partridge M

更新日期：2014-10-21 00:00:00

abstract：:Novel methods are presented which allow the estimation of the effect of stereotactic fiducial marker localization on target localization in a stereotactic surgery planning program based on the integration of image data from various modalities. The results of simulations are presented. A method for the evaluation of th...

journal_title：Physics in medicine and biology

authors： Lemieux L,Jagoe R

更新日期：1994-11-01 00:00:00

abstract：:Droplets of liquid perfluorocarbon (PFC) are under study as the next generation of contrast agents for ultrasound (US). These droplets can be selectively vaporized into echogenic gas bubbles in situ by externally applied US, with numerous applications to diagnosis and therapy. However, little is known about the mechan...

journal_title：Physics in medicine and biology

authors： Reznik N,Seo M,Williams R,Bolewska-Pedyczak E,Lee M,Matsuura N,Gariepy J,Foster FS,Burns PN

更新日期：2012-11-07 00:00:00

abstract：:We are developing a three-dimensional (3D) position-sensitive detector with isotropic spatial resolution, the X'tal cube. Originally, our design consisted of a crystal block for which all six surfaces were covered with arrays of multi-pixel photon counters (MPPCs). In this paper, we examined the feasibility of reducin...

journal_title：Physics in medicine and biology

authors： Hirano Y,Inadama N,Yoshida E,Nishikido F,Murayama H,Watanabe M,Yamaya T

更新日期：2013-03-07 00:00:00

abstract：:Joint space morphology can be indicative of the risk, presence, progression, and/or treatment response of disease or trauma. We describe a novel methodology of characterizing joint space morphology in high-resolution 3D images (e.g. cone-beam CT (CBCT)) using a model based on elementary electrostatics that overcomes a...

journal_title：Physics in medicine and biology

authors： Cao Q,Thawait G,Gang GJ,Zbijewski W,Reigel T,Brown T,Corner B,Demehri S,Siewerdsen JH

更新日期：2015-02-07 00:00:00

abstract：:Respiratory-correlated 4D-MRI can characterize respiratory-induced motion of tumors and organs-at-risk for radiotherapy treatment planning and is a necessity for image guidance of moving tumors treated on an MRI-linac. Essential for 4D-MRI generation is a robust respiratory surrogate signal. We investigated the feasib...

journal_title：Physics in medicine and biology

authors： Navest RJM,Mandija S,Bruijnen T,Stemkens B,Tijssen RHN,Andreychenko A,Lagendijk JJW,van den Berg CAT

更新日期：2020-01-13 00:00:00

abstract：:The extent to which occupational radiation exposure contributes to cancer mortality is an influence on future world energy policy. It is also a factor in deciding the level of expenditure to reduce radiation levels experienced by workers. Here we discuss some of the difficulties in analysing the situation and presen...

journal_title：Physics in medicine and biology

authors： Reissland JA,Kay P,Dolphin GW

更新日期：1976-11-01 00:00:00

abstract：:Dual-energy x-ray absorptiometry (DXA) is widely applied for estimating body fat. The percentage of body mass as fat (%fat) is predicted from a DXA-estimated R(ST) value defined as the ratio of soft tissue attenuation at two photon energies (e.g., 40 keV and 70 keV). Theoretically, the R(ST) concept depends on the mas...

journal_title：Physics in medicine and biology

authors： Wang Z,Heymsfield SB,Chen Z,Zhu S,Pierson RN

更新日期：2010-05-07 00:00:00

abstract：:In carbon-ion radiotherapy, single-beam delivery each day in alternate directions has been common practice for efficient operation, taking advantage of the Bragg peak and the relative biological effectiveness (RBE) for uniform dose conformation to a tumor. Treatments are usually fractionated and treatment plans are ev...

journal_title：Physics in medicine and biology

authors： Kanematsu N,Inaniwa T

更新日期：2017-02-07 00:00:00

abstract：:In this paper we present a novel method of reducing the dosimetric effects of the finite leaf width of a multileaf collimator (MLC) in conformal and intensity modulated radiotherapy (IMRT). This is achieved by decomposing the required high-resolution fluence distribution into two orthogonal components, which are deliv...

journal_title：Physics in medicine and biology

authors： Evans PM,Partridge M

更新日期：2000-03-01 00:00:00

abstract：:The Akaike information criterion and the associated Akaike weights (AW) rank pharmacokinetic models on the basis of goodness-of-fit and number of parameters. The usefulness of this information for improving the haemodynamic parameter estimates from DCE-MRI was investigated through two examples. In each of these, the e...

journal_title：Physics in medicine and biology

authors： Luypaert R,Ingrisch M,Sourbron S,de Mey J

更新日期：2012-06-07 00:00:00

abstract：:For proton therapy, an accurate conversion of CT HU to relative stopping power (RSP) is essential. Validation of the conversion based on real tissue samples is more direct than the current practice solely based on tissue substitutes and can potentially address variations over the population. Based on a novel dose exti...

journal_title：Physics in medicine and biology

authors： Zhang R,Baer E,Jee KW,Sharp GC,Flanz J,Lu HM

更新日期：2017-06-23 00:00:00

abstract：:A new multiplicative correction factor for tissue heterogeneities based on an exact expression for homogeneous non-unit-density media is proposed. O'Connor's density scaling theorem is invoked to evaluate the medium-specific tissue-maximum ratios used in the exact formulation. Monte Carlo calculations were performed a...

journal_title：Physics in medicine and biology

authors： Petti PL,Siddon RL,Bjärngard BE

更新日期：1986-10-01 00:00:00

abstract：:Non-invasively reconstructing the cardiac transmembrane potentials (TMPs) from body surface potentials can act as a regression problem. The support vector regression (SVR) method is often used to solve the regression problem, however the computational complexity of the SVR training algorithm is usually intensive. In t...

journal_title：Physics in medicine and biology

authors： Jiang M,Zhang H,Zhu L,Cao L,Wang Y,Xia L,Gong Y

更新日期：2015-04-21 00:00:00

abstract：:Dose factors for locations within a tissue-filled cylindrical cavity bounded by an infinite medium of bone labelled with an alpha-emitter are calculated by means of a Monte Carlo procedure. The calculational approach is general and allows us to determine dose factors for specific distances or target volumes defined by...

journal_title：Physics in medicine and biology

authors： Polig E

更新日期：1989-03-01 00:00:00

abstract：:Four-dimensional computed tomography (4D-CT) requires breathing information from the patient, and for this, several systems are available. Testing of these systems, under realistic conditions, requires a phantom with a moving target and an expandable outer contour. An anthropomorphic phantom was developed to simulate ...

journal_title：Physics in medicine and biology

authors： Vásquez AC,Runz A,Echner G,Sroka-Perez G,Karger CP

更新日期：2012-05-07 00:00:00

abstract：:Cavity theories are used to relate the dose in a medium to the dose in a cavity. No satisfactory analytical approach exists for the case of intermediate cavities, such as TLDs, when interface effects are important. Burlin proposed a general cavity theory that accounts for the cavity size but which ignores interface ef...

journal_title：Physics in medicine and biology

authors： Frujinoiu C

更新日期：2001-04-01 00:00:00

abstract：:Deep learning models are highly parameterized, resulting in difficulty in inference and transfer learning for image recognition tasks. In this work, we propose a layered pathway evolution method to compress a deep convolutional neural network (DCNN) for classification of masses in digital breast tomosynthesis (DBT). T...

journal_title：Physics in medicine and biology

authors： Samala RK,Chan HP,Hadjiiski LM,Helvie MA,Richter C,Cha K

更新日期：2018-05-01 00:00:00

abstract：:The total system error (TSE) of a CyberKnife® system was measured using two phantom-based methods and one patient-based method. The standard radiochromic film (RCF) end-to-end (E2E) test using an anthropomorphic head and neck phantom and isocentric treatment delivery was used with the 6Dskull, Fiducial and Xsight® spi...

journal_title：Physics in medicine and biology

authors： Pantelis E,Moutsatsos A,Antypas C,Zoros E,Pantelakos P,Lekas L,Romanelli P,Zourari K,Hourdakis CJ

更新日期：2018-08-20 00:00:00