Quantitative SEM-analysis of adhesive and thrombogenic properties of vascular prostheses.

abstract：:Patients with Familial Hyperlipoproteinaemia Type II showed evidence of increased platelet aggregability when compared to normal controls. This abnormality was not influenced by oral therapy with probucol whether or not the serum cholesterol levels were lowered during the study period. Probucol assays indicated adequa...

journal_title：Thrombosis research

authors： Bradlow BA,Chetty N,Birnbaum M,Baker SG,Seftel HC

更新日期：1982-04-15 00:00:00

abstract：:One of the major pathogens of periodontitis, Porphyromonas gingivalis (P. gingivalis), has the ability to aggregate human platelets. To investigate the interaction between P. gingivalis and human platelets in platelet rich plasma (PRP), platelet aggregation was measured by an aggregometer based on laser light scatteri...

journal_title：Thrombosis research

authors： Li X,Iwai T,Nakamura H,Inoue Y,Chen Y,Umeda M,Suzuki H

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The methodology of thromboprophylaxis post minimally invasive esophagectomy (MIE) is unclear. Thus, we compared the efficacy and safety of fondaparinux and nadroparin on the prophylaxis of venous thromboembolism (VTE) after MIE. MATERIALS AND METHODS:We conducted a randomized, double-blind, treatment-contro...

journal_title：Thrombosis research

authors： Song J,Xuan L,Wu W,Shen Y,Tan L,Zhong M

更新日期：2018-06-01 00:00:00

abstract：:Human plasma Lp(a) is susceptible to various sulfhydryl compounds. In this study we present evidence indicating that after treatment of Lp(a) with sulfhydryl compounds, immunoreactivity is changed, structural changes occur and functional characteristics regarding the numerous kringle structures in apo(a) disappear. Pu...

journal_title：Thrombosis research

authors： Leerink CB,van Ham AD,Heeres A,Duif PF,Bouma BN,van Rijn HJ

更新日期：1994-05-01 00:00:00

abstract：:The efficacy and the safety of a new urokinase dosage regimen (loading dose 250,000 IU, initial maintenance dosage 2,000 IU/kg/h in combination with heparin) was studied in ten cases of deep vein thrombosis with regard to the changes of the blood coagulation and fibrinolytic enzyme system. The coagulation analyses dem...

journal_title：Thrombosis research

authors： Schöffel G,Zimmermann R,Harenberg J,Mörl H

更新日期：1982-01-01 00:00:00

abstract：:We report here that the rate of fibrin polymerization is accelerated by decompression: the rate is essentially doubled by reducing the pressure by one-half (380 torr, 14.7 PSI or 1/2 ATM) and increased by 3.6 times with respect to the control at 25 torr (0.48 PSI or 1/30th ATM). We also report here that the rate of fi...

journal_title：Thrombosis research

authors： Murayama M

更新日期：1988-03-15 00:00:00

abstract：:A B S T R A C T Thrombotic events are a major cause of morbidity and mortality in cancer. While the association of venous thromboembolic events with cancer is well documented, in recent years arterial events (i.e. acute myocardial infarction and ischemic strokes) have also emerged as relatively common complications am...

journal_title：Thrombosis research

authors： Horowitz NA,Brenner B

更新日期：2020-07-01 00:00:00

abstract：:The interaction of platelets with collagen involves short aminoacid sequences which recur along the fibres. Platelet aggregation by collagen and serotonin release is inhibited by a synthetic octapeptide LYS-PRO-GLY-GLU- PRO-GLY-PRO-LYS- derived from type III collagen. In contrast, this octapeptide inhibits only weakly...

journal_title：Thrombosis research

authors： Karniguian A,Legrand YJ,Lefrancier P,Caen JP

更新日期：1983-12-15 00:00:00

abstract：:Stent implantation after balloon dilation of coronary arteries has improved clinical prognosis in patients undergoing transluminal coronary angioplasty (PTCA), but late restenosis remains a relevant problem. A previous study has indicated that PAI-1 activity changes immediately after PTCA without stent implantation ar...

journal_title：Thrombosis research

authors： Prisco D,Fedi S,Antonucci E,Capanni M,Chiarugi L,Chioccioli M,Falai M,Giglioli C,Abbate R,Gensini GF

更新日期：2001-11-01 00:00:00

abstract：:G619, a 4-OH-isophthalic acid derivative, was studied for its capacity to inhibit platelet aggregation. G619 dose-dependently inhibited U46619, collagen, ADP, PAF, thrombin and epinephrine-induced platelet aggregation in vitro. The IC50 values for inhibition of U46619-induced human and rabbit platelet aggregation were...

journal_title：Thrombosis research

authors： Yue TL,Smith EF 3rd,Ohlstein EH,Sulpizio A,Slivjak MJ,Rabinovici R,Sellers TS,Lynch KM,Poyser R,Feuerstein G

更新日期：1992-05-15 00:00:00

abstract：:Selected coagulation and fibrinolytic parameters were assessed in 40 insulin dependent diabetes mellitus patients with varying degrees of metabolic control; 30 healthy subjects matched for age and sex formed the control group. Activated Partial Thromboplastin Time, Prothrombin Time, Fibrinogen, Factor VII, Antithrombi...

journal_title：Thrombosis research

authors： Carmassi F,Morale M,Puccetti R,De Negri F,Monzani F,Navalesi R,Mariani G

更新日期：1992-09-15 00:00:00

abstract：:An abnormal prothrombin has been detected in a 26-year-old female, who had no history of excessive bleeding. Prothrombin activity was approximately 10% when measured using either the classical one-stage assay or the assay with Echis carinatus venom, whereas prothrombin antigen level was normal. In keeping with current...

journal_title：Thrombosis research

authors： Morishita E,Saito M,Asakura H,Jokaji H,Uotani C,Kumabashiri I,Yamazaki M,Hachiya H,Okamura M,Matsuda T

更新日期：1991-06-15 00:00:00

abstract：:Lipoprotein-Associated Coagulation Inhibitor (LACI) is a factor Xa dependent inhibitor of the factor VII(a)/Tissue Factor catalytic complex. Deduced from partial cDNA sequence, LACI's amino acid sequence has recently been reported. Northern blot analysis showed LACI cDNA hybridizes to RNAs of 1.4 and 4.0 kb in size. T...

journal_title：Thrombosis research

authors： Girard TJ,Warren LA,Novotny WF,Bejcek BE,Miletich JP,Broze GJ Jr

更新日期：1989-07-01 00:00:00

abstract：:To determine whether homocysteine, a risk factor for possible endothelial cell dysfunction, procoagulant effects and premature vascular disease but with a potential nutritional role for fetal and neonatal metabolism and development, is elevated in women at time of elective caesarean section with nitrous oxide general ...

journal_title：Thrombosis research

authors： Zanardo V,Caroni G,Burlina A

更新日期：2003-01-01 00:00:00

abstract：:Murine monoclonal antibodies (mAb) were raised to a purified product of bovine PF-4, a 9,500 dalton protein with heparin neutralization activity comparable to that of human PF-4. Using a non-radioactive slide immunoenzymatic assay, four major classes of mAb could be identified when comparisons were made between purifi...

journal_title：Thrombosis research

authors： Ciaglowski RE,Martinez J,Ryan TJ,Lewandowski LJ,Barnhart MI,Weller MA,Chen ST,Walz DA

更新日期：1986-03-15 00:00:00

abstract：:Thrombolysis is an effective but potential deleterious therapy and should therefore be limited to patients with acute intracerebral vessel occlusion and salvageable tissue. MRI currently develops towards the new diagnostic standard for the selection of stroke patients eligible for acute thrombolytic treatment and acut...

journal_title：Thrombosis research

authors： Röther J

更新日期：2001-09-30 00:00:00

abstract：BACKGROUND:The recanalization rate in patients with deep venous thrombosis (DVT) of the legs treated with the direct oral anticoagulants (DOAC) is unknown. METHODS:In an Italian cohort, we investigated the rate of residual vein thrombosis (RVT) after three and/or six months in 352 patients with proximal DVT who had be...

journal_title：Thrombosis research

authors： Prandoni P,Ageno W,Mumoli N,Zanatta N,Imberti D,Visonà A,Ciammaichella M,Simioni L,Cappelli R,Bucherini E,Di Nisio M,Avruscio G,Camporese G,Parisi R,Cuppini S,Turatti G,Noventa F,Sarolo L

更新日期：2017-05-01 00:00:00

abstract：:Effects of mechanical trauma of platelets and red blood cells on dynamic viscoelasticity of blood during clotting were examined. Two different methods were attempted to give the mechanical damage to blood cells. In one method, a flow apparatus consisting of a thin teflon tube and two sample reservoirs connecting to bo...

journal_title：Thrombosis research

authors： Kaibara M,Ukiya Y,Sekiguchi M

更新日期：1986-08-15 00:00:00

abstract：:Deep vein thrombosis and pulmonary embolism, collectively termed venous thromboembolism (VTE), affect over 1 million Americans each year. VTE is triggered by inflammation and blood stasis leading to the formation of thrombi rich in fibrin and red blood cells (RBCs). However, little is known about mechanisms regulating...

journal_title：Thrombosis research

authors： Aleman MM,Walton BL,Byrnes JR,Wolberg AS

更新日期：2014-05-01 00:00:00

abstract：:There are some issues in the current factor (F)VIII replacement therapy for severe hemophilia A. One is mental and physical burden for the multiple intravenous infusions, and the other is difficulty in the hemostatic treatment for the patients with FVIII inhibitor. The development of novel drug with fully hemostatic e...

journal_title：Thrombosis research

authors： Nogami K

更新日期：2016-05-01 00:00:00

abstract：:Cell based models of coagulation (CBM) have provided mechanistic insight into numerous hematological issues for nearly two decades. This review discusses another coagulation model system--the clot lifespan model (CLSM)--that has been designed to compliment the CBM-based approach to elucidating the mechanisms responsib...

journal_title：Thrombosis research

authors： Nielsen VG

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Plasminogen activator inhibitor (PAI-1) may have an independent prognostic value in breast cancer (BC). PAI-1 4G/5G polymorphism may have significance for antigen expression. Thus, we analyzed the possible associations between PAI-1 4G/5G polymorphism, plasma PAI-1 levels, and clinicopathological features ...

journal_title：Thrombosis research

authors： Palmirotta R,Ferroni P,Savonarola A,Martini F,Ciatti F,Laudisi A,Sini V,Del Monte G,Guadagni F,Roselli M

更新日期：2009-09-01 00:00:00

abstract：:When single-chain pro-UK is activated by plasmin or kallikrein, the Lys158-Ile159 bond is cleaved, leaving a C-terminal lysine on the A-chain (Lys-UK). Two-chain, high molecular weight urokinase (UK) purified from urine, however, has been shown to contain a phenylalanine residue as the C-terminal of the A-chain (Phe-U...

journal_title：Thrombosis research

authors： Lenich C,Pannell R,Gurewich V

更新日期：1991-10-01 00:00:00

abstract：:Blood was obtained from four patients envenomated by the Australian common brown snake, Pseudonaja textilis textilis. This elapid snake has one of the most toxic venoms in the world, containing extremely potent neurotoxic and coagulant components. The latter is a potent complete prothrombinase, converting prothrombin ...

journal_title：Thrombosis research

authors： Masci PP,Rowe EA,Whitaker AN,de Jersey J

更新日期：1990-09-01 00:00:00

abstract：:Endothelial cells synthesize and release different proteins involved in their function, and some of these proteins may play important roles in the cellular response to injury, infection, or glucocorticoids. We have examined the profile of proteins released from rabbit coronary microvascular endothelial (RCME) and huma...

journal_title：Thrombosis research

authors： Partridge CA,Gerritsen ME

更新日期：1990-01-01 00:00:00

abstract：:Human antithrombin III was demonstrated to bind plasminogen specifically in a time and concentration-dependent manner. The above binding was also confirmed using ligand western blot assays. The interaction of plasminogen was significantly (>90%) inhibited by lysine, indicating the involvement of kringles in binding an...

journal_title：Thrombosis research

authors： Dudani AK

更新日期：2000-09-15 00:00:00

abstract：INTRODUCTION:Patients with intracerebral hemorrhage during rivaroxaban treatment have small hematoma and favorable outcomes compared with those with warfarin. We investigated its possible mechanism, focusing on prothrombin fragment 1+2 (F1+2), a marker of thrombin generation. MATERIALS AND METHODS:In 65 patients with ...

journal_title：Thrombosis research

authors： Hagii J,Tomita H,Metoki N,Tamai Y,Saito S,Shiroto H,Hitomi H,Kamada T,Seino S,Takahashi K,Sasaki S,Yasujima M,Okumura K

更新日期：2016-12-01 00:00:00

abstract：CONTEXT:Recently, there has been an increasing number of reports of incidental pulmonary embolism (PE) in patients undergoing chest computer tomography (CT) for reasons other than the research of suspected PE. Natural history of incidental PE remains unclear. OBJECTIVES:To estimate the prevalence of incidental PE, to ...

journal_title：Thrombosis research

authors： Dentali F,Ageno W,Becattini C,Galli L,Gianni M,Riva N,Imberti D,Squizzato A,Venco A,Agnelli G

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Whether antibodies directed to β2-Glycoprotein I (aβ2GPI) are responsible for LA activity is not well defined. However, in the absence of such antibodies the molecule responsible for LA phenomenon is unknown. OBJECTIVE:The aim of this study was the biochemical identification of the target antigen epitope of...

journal_title：Thrombosis research

authors： Pengo V,Del Ross T,Ruffatti A,Bison E,Cattini MG,Pontara E,Testa S,Legnani C,Pozzi N,Peterle D,Acquasaliente L,De Filippis V,Denas G

更新日期：2018-12-01 00:00:00

abstract：:The present investigation has used an aggregation-disaggregation-reaggregation model to determine if exposure to potent aggregating agents causing a refractory state in deaggregated platelets results in down-regulation and clearance of GPIb/IX, the receptor for von willebrand factor. Thrombin, the thrombin receptor ac...

journal_title：Thrombosis research

authors： White JG,Rao GH

更新日期：1996-11-15 00:00:00