Inhibition of gastrin secretion by pirenzepine (LS 519) in treatment of gastric ulcer.

Abstract:

:The effects of pirenzepine on the serum gastrin levels in the basal state and in response to a liquid test meal were investigated in nine patients with gastric ulcer. Single-dose administration of the drug caused a significant decrease in the basal gastrin level and significant inhibition of the serum gastrin response. When measured 12 h after the end of drug treatment for 7 days, the serum gastrin levels in the basal state and in response to a test meal tended to be high, but the differences were not statistically significant.

journal_name

Scand J Gastroenterol

authors

Tatsuta M,Itoh T,Okuda S,Tamura H,Baba M,Yamamura H

doi

10.3109/00365528109181967

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

269-71

issue

2

eissn

0036-5521

issn

1502-7708

journal_volume

16

pub_type

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