Abstract:
:This article reviews the development of the WHO project on the histological classification of tumours, which has included the establishment of several collaborating centres and has involved more than 300 pathologists in over 50 countries. The project has resulted in the publication, over the last 14 years, of 25 volumes in the first series of the International Histological Classification of Tumours (IHCT), each giving a classification of tumours specific to a certain site. The classifications are based primarily on the microscopic characteristics of the tumours and are concerned with morphologically identifiable cell types and histological patterns as seen by means of light microscopy and conventional staining techniques. The article also describes the relationship between IHCT and other classification and coding systems and assesses possible future developments that may result from new approaches to diagnosis.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Sobin LHsubject
Has Abstractpub_date
1981-01-01 00:00:00pages
813-9issue
6eissn
0042-9686issn
1564-0604journal_volume
59pub_type
杂志文章abstract::Reported is an enzyme-linked immunosorbent assay (ELISA) that has been optimized and validated for the determination of chloroquine in urine or dried blood spots. The assay employs antisera raised in sheep to a chloroquine derivative conjugated to keyhole limpet haemocyanin and chloroquine conjugated to porcine thyrog...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::A total of 100 male Zambian patients with symptomatic falciparum malaria were treated with either two tablets of mefloquine plus sulfadoxine-pyrimethamine (Fansimef) or three tablets of sulfadoxine-pyrimethamine (Fansidar) as a single dose. The patients were kept under observation from day 0 (day of treatment) to day ...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1987-01-01 00:00:00
abstract::In 1995, the WHO Regional Office for Africa launched a logistics project to address the four main areas of immunization logistics: the cold chain, transport, vaccine supply and quality, and the safety of injections in the countries of the region. The impact of this logistic approach on immunization injection safety wa...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:Objective:To analyse the demographic and clinical characteristics of people attending physical rehabilitation centres run or supported by the International Committee of the Red Cross in countries and territories affected by conflict. Methods:Of 150 such rehabilitation centres worldwide, 38 use an electronic patient ma...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.19.249060
更新日期:2020-09-01 00:00:00
abstract::The results of comparative assays have revealed considerable variation in the potencies of tetanus toxoids produced in different laboratories. Some manufacturers are able consistently to produce toxoids high in potency; others are not able to do so. While further work is required in order to correlate the animal assay...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1955-01-01 00:00:00
abstract::The spot hybridization assay for the detection of Plasmodium falciparum reported here uses as probe a repetitive DNA sequence from this species and exhibits a high degree of species specificity. Isolates from African, Asian, and South American patients were positive in the assay and gametocytes could be detected at th...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Osteoporosis is a major public health problem, affecting millions of people worldwide. The associated health care costs are growing in parallel with increases in elderly populations, and it is expected that the number of osteoporotic fractures will double over the next 50 years. The best way to address osteoporosis is...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:Objective:To analyse and improve the Namibian maternity care system by implementing maternal near-miss surveillance during 1 October 2018 and 31 March 2019, and identifying the challenges and benefits of such data collection. Methods:From the results of an initial feasibility study, we adapted the World Health Organiz...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.20.251371
更新日期:2020-08-01 00:00:00
abstract::This literature review indicates that menstrual regulation during the fifth to seventh week of pregnancy is not always as free from risk as has sometimes been claimed. In particular, it has a higher failure rate, in terms of continued pregnancy, than has abortion by suction in later stages of pregnancy.Vacuum aspirati...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::The distribution and epidemiology of parasitic diseases in both urban and periurban areas of endemic countries have been changing as development progresses. The following different scenarios involving Chagas disease, lymphatic filariasis, leishmaniasis and schistosomiasis are discussed: (1) infected persons entering n...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Forecasts of tuberculosis morbidity and mortality are presented for the decade 1990-99. An estimated 88 million new cases of tuberculosis, of which 8 million will be attributable to HIV infection, will occur in the world during the decade; 30 million people are predicted to die of tuberculosis in the same period, incl...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Since the development of insecticide-resistance and the consequent partial failure of the chemical approach to the control of disease vectors, interest in the biological approach has re-awakened. An aspect of the latter approach that is of great current interest is "autocidal control"-that is, the use of insects for t...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1963-01-01 00:00:00
abstract::With the introduction of direct-acting antiviral drugs, treatment of hepatitis C is both highly effective and tolerable. Access to treatment for patients, however, remains limited in low- and middle-income countries due to the lack of supportive health infrastructure and the high cost of treatment. Poorer countries ar...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.16.183772
更新日期:2018-01-01 00:00:00
abstract::A technique is described whereby it is possible to make an accurate determination of the physiological age of anopheline females, i.e., the number of gonotrophic cycles through which the female has passed. This technique is based on counts of the dilatations left in the ovarioles subsequent to each maturation of folli...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1959-01-01 00:00:00
abstract::The author reviews the agricultural use of night-soil, sewage, and sewage sludge from two points of view: the purely agricultural and the sanitary.Knowledge of the chemistry and bacteriology of human faecal matter is still rather scant, and much further work has to be done to find practical ways of digesting night-soi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1954-01-01 00:00:00
abstract:OBJECTIVE:To estimate out-of-pocket costs and the incidence of catastrophic health expenditure in people admitted to hospital with acute coronary syndromes in Asia. METHODS:Participants were enrolled between June 2011 and May 2012 into this observational study in China, India, Malaysia, Republic of Korea, Singapore, T...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.15.158303
更新日期:2016-03-01 00:00:00
abstract::Mental health services are becoming more widely available than ever before to the Syrian population in spite of the crisis. Dale Gavlak reports. ...
journal_title:Bulletin of the World Health Organization
pub_type: 新闻
doi:10.2471/BLT.16.020116
更新日期:2016-01-01 00:00:00
abstract::The authors first discuss the principle of the Treponema pallidum immobilization (TPI) test, considered both as a qualitative and as a quantitative test, and then various specific aspects of passage of the Nichols strain of treponeme in rabbit testes. A number of important technical details and modifications in the te...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1956-01-01 00:00:00
abstract::The Haemosporidia, which comprise the malaria parasites, have probably evolved from Coccidia of the intestinal epithelium of the vertebrate host by adaptation first to some tissues of the internal organs and then to life in the circulating cells of the blood.The present opinion is that, among the malaria parasites of ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1965-01-01 00:00:00
abstract::Health interventions vary substantially in the degree of effort required to implement them. To some extent this is apparent in their financial cost, but the nature and availability of non-financial resources is often of similar importance. In particular, human resource requirements are frequently a major constraint. W...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:/S0042-96862005000400013
更新日期:2005-04-01 00:00:00
abstract::Investigators using questionnaires are usually confronted with an enormous number of different responses whose significance with respect to a particular characteristic is not immediately clear. This paper presents a simple computational technique for determining the relative merits of each question and a score for eac...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
abstract::This article surveys the attitudes and perceptions of a random sample of the elderly population in three regions of Italy on the use and efficacy of influenza vaccine. The data were collected by direct interviews using a standard questionnaire. The results show that vaccination coverage against influenza is inadequate...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of adequate monitoring and the costs of measuring CD4+ T-lymphocytes (CD4+ cell) and human immunodeficiency virus (HIV) viral load in people receiving antiretroviral therapy (ART) in seven countries in the WHO Region of the Americas. METHODS:We obtained retrospective, longitudinal...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.14.147447
更新日期:2015-08-01 00:00:00
abstract::Histochemical staining methods for acid phosphatase were used to study the differences among microfilariae of various West African strains of Onchocerca volvulus in both forest and Sudan-savanna onchocerciasis zones. The results have shown statistically significant differences in the staining patterns of microfilarial...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::The insecticidal activity of synthetic pyrethroids was compared with that of the natural pyrethrins, which have been used on a world-wide scale as active ingredients for insecticidal aerosols or mosquito coils.All of the synthetic pyrethroids were found to be more stable than the pyrethrins. Tetramethrin showed a very...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1971-01-01 00:00:00
abstract:PROBLEM:Indoor residual spraying and long-lasting insecticidal nets (LLINs) are key tools for malaria vector control. Malawi has struggled to scale up indoor residual spraying and to improve LLIN coverage and usage. APPROACH:In 2002, the Malawian National Malaria Control Programme developed guidelines for insecticide ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.15.154245
更新日期:2016-06-01 00:00:00
abstract::In a continuing search for more effective molluscicides, tests were carried out in the Egypt-49 area on Molucid and WL 8008. Molucid, a 35% w/v solution of isobutyltriphenyl-methylamine (ICI 24223), was applied at 2 ppm for 6 hours; after the treatment, no live Bulinus truncatus, Biomphalaria alexandrina or Lymnaea ca...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1966-01-01 00:00:00
abstract::Up-to-date information is given on the epidemiological situation of zoonotic visceral leishmaniasis (ZVL) in nine Mediterranean countries, and on drug regimens adopted in the management of ZVL patients in each country. Results of experimental and clinical trials on the efficacy and tolerability of liposomal amphoteric...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1995-01-01 00:00:00
abstract::User fees are used to recover costs and discourage unnecessary attendance at primary care clinics in many developing countries. In South Africa, user fees for children aged under 6 years and pregnant women were removed in 1994, and in 1997 all user fees at all primary health care clinics were abolished. The intention ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract:Objective:To determine the prevalence of and factors associated with dispensing antibiotics without a prescription in online and community pharmacies in China. Methods:We conducted a nationwide cross-sectional study of online and community pharmacies in 27 cities and counties in nine provinces in China (selected by mu...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.19.242370
更新日期:2020-07-01 00:00:00