Molecular regulation of autophagy and its implications for metabolic diseases.

abstract：PURPOSE OF REVIEW:To evaluate whether the diet of lactating women modulates the development of allergic disease in their children. RECENT FINDINGS:Although maternal avoidance of common food protein allergens was previously recommended for lactating women with infants predisposed to allergic disease, recent expert revi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Palmer DJ,Makrides M

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The major components of ERAS attenuate the inflammatory response and modulate metabolism in direction of sparing body protein and preserving function. However, these perioperative interventions might have limited effectiveness on postoperative outcomes if preoperative risk factors are not addressed an...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Chabot K,Gillis C,Carli F

更新日期：2020-07-01 00:00:00

abstract：:Different types of dietary fatty acids have distinct, and sometimes opposing, effects on endothelial cell function. Long-chain n-3 polyunsaturated fatty acids from fish oil (eicosapentaenoic-acid-20:5n-3 and docosahexaenoic-acid-22:6n-3) attenuate cytokine-induced adhesion molecule expression (mRNA and protein) while ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wahle KW,Rotondo D

更新日期：1999-03-01 00:00:00

abstract：:Despite the extensive current literature on ethics, very few publications have specifically addressed the ethical issues surrounding the provision of nutrition to perioperative patients. Four publications are particularly relevant and highly recommended [1-4]. This review is an attempt to draw attention to those ethic...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： MacFie J

更新日期：2000-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Until relatively recently, the only significant source of lactoferrin in the diet was human lactoferrin, provided in breast milk. Today, however, bovine lactoferrin, isolated by dairy technology, as well as recombinant human lactoferrin are commercially available and can be added to foods and clinical...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lönnerdal B

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity is associated with low-grade chronic inflammation in adipose tissue. This review presents an update on human and rodent studies analyzing the nature of fat-infiltrating immune cells, the time course of adipose tissue infiltration and underlying mechanisms. RECENT FINDINGS:Intensive studies in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sell H,Eckel J

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review summarizes recent evolutions in knowledge and discusses the concept of whom and when parenteral nutrition should be considered in critically ill patients as a total form of nutrition, in a supplemental form, or never. RECENT FINDINGS:Recent developments in our understanding of the ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ridley EJ

更新日期：2020-12-10 00:00:00

abstract：:Studies of many different rodent models of muscle wasting have indicated that accelerated proteolysis via the ubiquitin-proteasome pathway is the principal cause of muscle atrophy induced by fasting, cancer cachexia, metabolic acidosis, denervation, disuse, diabetes, sepsis, burns, hyperthyroidism and excess glucocort...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Jagoe RT,Goldberg AL

更新日期：2001-05-01 00:00:00

abstract：:Catabolism of fat-free mass affects both the quality of life and survival of patients. Because of variations in fluid status during acute illness, changes in body weight are difficult to evaluate and interpret during treatment. Nutritional assessment should therefore evaluate fat-free and fat mass changes during metab...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kyle UG,Pichard C

更新日期：2000-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Size at birth is critical in determining life expectancy with both small and large neonates at risk of shortened life spans. This review examines the hormonal and nutritional drivers of intrauterine growth with emphasis on the role of foetal hormones as nutritional signals in utero. RECENT FINDINGS:N...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sferruzzi-Perri AN,Vaughan OR,Forhead AJ,Fowden AL

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this study was to highlight recent evidence on protein requirement and physical activity recommendations in older adults and their interrelationship. RECENT FINDINGS:Higher protein intake in older adults is beneficial for better physical function, reduced fracture risk, healthy ageing and ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Yeung SSY,Chan RSM,Woo J

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss transcriptional mechanisms regulating hepatic lipid metabolism. RECENT FINDINGS:Humans who are obese or have diabetes (NIDDM) or metabolic syndrome (MetS) have low blood and tissue levels of C20-22 polyunsaturated fatty acids (PUFAs). Although the impact of low C20-22 PUFAs on disease prog...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Jump DB

更新日期：2011-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review provides an update on secreted factors and mechanisms that promote a thermogenic program in beige adipocytes, and their potential roles as therapeutic targets to fight obesity. RECENT FINDINGS:We outline recent studies revealing unrecognized mechanisms controlling beige adipocyte p...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： McQueen AE,Koliwad SK,Wang JC

更新日期：2018-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The obesity paradox is a highly controversial concept that may be attributed to methodological limitations related to its identification. One of the primary concerns is the use of BMI to define obesity. This index does not differentiate lean versus adipose tissue compartments (i.e. body composition) c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Prado CM,Gonzalez MC,Heymsfield SB

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Trehalose is a disaccharide with manifold industrial, commercial and biomedical uses. In the decade following its initial definition as an autophagy-inducing agent, significant advances have been realized in regard to the applicable clinical and preclinical contexts in which trehalose can be deployed....

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Zhang Y,DeBosch BJ

更新日期：2019-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine the stability and compatibility of histamine H2-receptor antagonists in parenteral nutrition admixtures in order to provide well tolerated and effective therapy. RECENT FINDINGS:Many stability investigations were carried out before 2005, but no critical appraisal of published data has been...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Puzovic M,Hardy G

更新日期：2007-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The increase in obesity in developed societies drives interest in the interplay of energy intake, metabolic energy expenditure, and body energy stores. A better understanding of energy management in physically active and undernourished humans should help guide strategies to manage obesity safely and e...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hoyt RW,Friedl KE

更新日期：2006-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses upon the biology and metabolism of a trace component in foods called nicotinamide riboside. Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD), and is a source of Vitamin B3. Evidence indicates that nicotinamide riboside has unique properties as a Vitam...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Chi Y,Sauve AA

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Objective and subjective methods are used to assess nutritional status. They are used as diagnostic, prognostic and response tools. It is still controversial which of them is more suitable for each situation and what they are really assessing. The most recent findings about these methods will be discu...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Barbosa-Silva MC

更新日期：2008-05-01 00:00:00

abstract：PURPOSE OF REVIEW:There is increasing clinical and pathophysiological evidence that a premature aging process is involved in the pathogenesis of systemic complications of many chronic organ diseases, which result in analogous phenotypes, including premature vascular aging, osteoporosis and muscle wasting. Novel develop...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kooman JP,Shiels PG,Stenvinkel P

更新日期：2015-11-01 00:00:00

abstract：:Lipophilic molecules can passively diffuse across cell membranes, a process that is driven by the concentration gradient, by availability of acceptors to facilitate desorption from the bilayer, and by cellular metabolism. However, evidence has accumulated that supports the existence of specialized, protein-facilitated...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Abumrad NA,Sfeir Z,Connelly MA,Coburn C

更新日期：2000-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The gastrointestinal tract plays an important role in the maintenance of fluid and electrolyte balance, and its diseases cause disturbances in that balance. Conversely, fluid and electrolyte disorders may disturb gastrointestinal function. The purpose of this review is to highlight some recent literat...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Macafee DA,Allison SP,Lobo DN

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this overview is to highlight the multiple ways in which oxidative stress could be exacerbating muscle wasting. Understanding these interactions in vivo will assist in identifying opportunities for more targeted therapies to reduce skeletal muscle wasting. RECENT FINDINGS:There are many ex...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Arthur PG,Grounds MD,Shavlakadze T

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been growing evidence that lifestyle factors may affect the health and lifespan of an individual by affecting telomere length. The purpose of this review was to highlight the importance of telomeres in human health and aging and to summarize possible lifestyle factors that may affect health ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Shammas MA

更新日期：2011-01-01 00:00:00

abstract：:Food products have variously been reported as causing, perpetuating or treating irritable bowel syndrome. The evidence for this is reviewed with regard to recent studies investigating symptom reporting, mono- and disaccharide malabsorption and probiotics. The development of objective measures remains an urgent priorit...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dunlop SP,Spiller RC

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition is highly prevalent in hospitalized patients. Despite this, it is not routinely assessed in most hospitals worldwide. One of the reasons that might explain this fact is that there is no gold-standard nutritional assessment tool, and much has been written advocating this or that technique....

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Waitzberg DL,Correia MI

更新日期：2003-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle and lean body mass may be vital to prognosis and functional recovery in chronic and acute illness, particularly in conditions in which muscle atrophy is prevalent. Ultrasound provides a precise and expedient method to measure muscle mass and changes in skeletal muscle at the bedside. ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Mourtzakis M,Wischmeyer P

更新日期：2014-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Improving our understanding of factors driving fat gain in young children should increase our ability to manage the rising problem of obesity. Accordingly, studies associating timing of adiposity rebound with later obesity are reviewed. RECENT FINDINGS:Investigations in many countries have confirmed ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Taylor RW,Grant AM,Goulding A,Williams SM

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Poor vitamin K nutrition has recently been linked to several chronic diseases associated with abnormal calcification, which affect many elderly. To understand the impact of vitamin K nutrition on healthy aging it is necessary to assess both the determinants and the adequacy of vitamin K nutritional st...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Booth SL

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The main aim of this review is to summarize current knowledge of tumor protein p53-inducible nuclear protein 2 (TP53INP2) function and its role in skeletal muscle proteostasis. RECENT FINDINGS:Autophagy is directly involved in the regulation of skeletal muscle mass. Thus, excessive autophagy is assoc...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sala D,Zorzano A

更新日期：2015-05-01 00:00:00