Lipid transporters: membrane transport systems for cholesterol and fatty acids.

abstract：PURPOSE OF REVIEW:Obesity is associated with low-grade chronic inflammation in adipose tissue. This review presents an update on human and rodent studies analyzing the nature of fat-infiltrating immune cells, the time course of adipose tissue infiltration and underlying mechanisms. RECENT FINDINGS:Intensive studies in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sell H,Eckel J

更新日期：2010-07-01 00:00:00

abstract：:The nuclear factor kappa B family of inducible transcription factors regulates the expression of many genes. Nuclear factor kappa B has been implicated in autoimmune and inflammatory diseases, infection, cell survival, and cell transformation with subsequent promotion of cancer. In this review, we summarize features o...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Holmes-McNary M

更新日期：2002-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular function is recognized as an early and integrative marker of cardiovascular disease. While there is consistent evidence that the quantity of dietary fat has significant effects on vascular function, the differential effects of individual fatty acids is less clear. This review summarizes recen...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lovegrove JA,Griffin BA

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent literature suggests dietary glutamine supplementation may lower blood glucose in patients with type 1 diabetes (T1D), who have no residual insulin secretion. The mechanisms and potential relevance to the care of T1D remain unclear. RECENT FINDINGS:Glutamine is involved in multiple pathways inc...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Darmaun D,Torres-Santiago L,Mauras N

更新日期：2019-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This article provides an overview of the most recent molecular and clinical outcomes of studies that investigate the effect of weight loss and calorie restriction on carbohydrate metabolism, obtained either by dieting or bariatric surgery. It will focus on aspects of carbohydrate metabolism related to...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Manco M,Mingrone G

更新日期：2005-07-01 00:00:00

abstract：:The problem with any attempt to feed patients in multiple organ failure is that, because of an ongoing inflammatory process, the conventional techniques of supplying energy and protein do not maintain lean tissue mass. In addition, the conventional markers of nutritional status, both anthropometric (body mass and comp...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Campbell IT

更新日期：1998-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The role of calorie restriction in humans is controversial. Recently, new data in monkeys and humans have provided new insights into the potential role of calorie restriction in longevity. RECENT FINDINGS:A study in rhesus monkeys showed a reduction in aging-associated mortality. A number of controll...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Morley JE,Chahla E,Alkaade S

更新日期：2010-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this overview is to highlight the multiple ways in which oxidative stress could be exacerbating muscle wasting. Understanding these interactions in vivo will assist in identifying opportunities for more targeted therapies to reduce skeletal muscle wasting. RECENT FINDINGS:There are many ex...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Arthur PG,Grounds MD,Shavlakadze T

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The function and use of vitamin D supplementation has become very controversial. This review attempts to provide a balanced perspective with respect to the experimental findings published in the past 18 months. RECENT FINDINGS:The recent contrasts between the Institute of Medicine (IOM) report and th...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hollis BW

更新日期：2011-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Sarcopenia is a progressive generalized decline in skeletal muscle mass, strength, and function. This condition is highly prevalent in critically ill patients and is associated with poor outcomes in the ICU. In this review, we describe the use, evidence, and limitations of the most common validated im...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lopez-Ruiz A,Kashani K

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the literature concerning the relationship between meal patterns and childhood obesity. Literature searches of MEDLINE and the Cochrane Library were performed in October 2009 for studies published in the last 18-24 months. RECENT FINDINGS:Available data indicate that not only meal compos...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Patro B,Szajewska H

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The pathogenesis of coronary heart disease is of multifactorial origin. Probably, not all risk factors are satisfactorily understood. This article outlines beneficial vitamin D effects on cardiac function and the vasculature. In addition, human data associating serum vitamin D metabolite levels or ora...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Zittermann A,Koerfer R

更新日期：2008-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Overweight and obesity represent a significant health burden during pregnancy, placing women and their infants at increased risk of adverse health outcomes. Although there is considerable observational literature describing the effect of gestational weight gain in pregnancy, research efforts have focu...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dodd JM,O'Brien CM,Grivell RM

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The inflammatory response is essential in the response to pathogens. TNF-alpha, IL-1 and IL-6 are key mediators of the response. They initiate metabolic changes to provide nutrients for the immune system, from host tissues. These changes include hyperlipidemia and increased gluconeogenesis. Insulin re...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Grimble RF

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Large-scale clinical trials have failed to demonstrate a benefit for vitamin E supplementation in cardiovascular prevention. This contrasts with previous epidemiological studies indicating that individuals with high vitamin E status benefit from protection against chronic illnesses, including cardiova...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hacquebard M,Carpentier YA

更新日期：2005-03-01 00:00:00

abstract：:Food products have variously been reported as causing, perpetuating or treating irritable bowel syndrome. The evidence for this is reviewed with regard to recent studies investigating symptom reporting, mono- and disaccharide malabsorption and probiotics. The development of objective measures remains an urgent priorit...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dunlop SP,Spiller RC

更新日期：2001-11-01 00:00:00

abstract：:This review examines recent advances in the dietary modulation of gene expression in the gastrointestinal tract. We have chosen to concentrate on individual genes and examine what is known about their regulation, attempting to link different studies together. ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kelly EJ,Sanderson IR

更新日期：1999-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine recent findings related to the influence of omega-3 (ω-3) fatty acid supplementation on skeletal muscle anabolism with a particular focus on situations of skeletal muscle disuse. RECENT FINDINGS:Skeletal muscle disuse results in a reduction in fed and fasted rates of skeletal muscle protei...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ferguson EJ,Seigel JW,McGlory C

更新日期：2020-12-15 00:00:00

abstract：:Different types of dietary fatty acids have distinct, and sometimes opposing, effects on endothelial cell function. Long-chain n-3 polyunsaturated fatty acids from fish oil (eicosapentaenoic-acid-20:5n-3 and docosahexaenoic-acid-22:6n-3) attenuate cytokine-induced adhesion molecule expression (mRNA and protein) while ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wahle KW,Rotondo D

更新日期：1999-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective of this review has been to analyse and compare the causes, incidence, severity and treatment of gastrointestinal complications in critically ill children and adults. RECENT FINDINGS:The incidence of gastrointestinal complications in critically ill patients published in the literature is...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： López-Herce J

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, the latest evidence on the influence of dietary protein and plasma amino acids in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) is discussed. RECENT FINDINGS:Increasing protein consumption during weight loss and maintenance may help reduce liver fat content. Conversely,...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Tricò D,Biancalana E,Solini A

更新日期：2021-01-01 00:00:00

abstract：:New results on the physiological properties of conjugated linoleic acid have been published by several working groups, especially showing the effects of single conjugated linoleic acid isomers on carcinogenesis and body composition. Recently, other studies have shown that conjugated linoleic acid has an influence on d...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sébédio JL,Gnaedig S,Chardigny JM

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent advances pertaining to the mechanisms regulating brain docosahexaenoic acid (DHA) uptake. DHA is an omega-3 polyunsaturated fatty acid highly enriched in neuronal membranes and it is implicated in several important neurological processes. However, DHA synthesis is extremely limited...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Chouinard-Watkins R,Lacombe RJS,Bazinet RP

更新日期：2018-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the interest of functional food in low-income countries by analyzing various necessary factors. RECENT FINDINGS:Being on a low income would appear to relate most often to an unbalanced diet, both qualitatively and quantitatively, which may be damaging to health in the long term. Most ch...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Das A,Chakraborty R

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the impact of microRNA on myogenesis and muscle wasting in order to provide valuable information for clinical investigation. RECENT FINDINGS:Muscle wasting increases the risk of morbidity/mortality in primary muscle diseases, secondary muscle disorders and elderly population. Muscle mas...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wang XH

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the potential benefits of increased dietary protein during weight loss and the importance of distribution of high-quality protein at each meal. RECENT FINDINGS:Popular weight loss diets emphasize use of protein as a substitute for carbohydrates or fat to reduce insulin and minimize hung...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Devkota S,Layman DK

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:There is considerable interest in glutamine and selenium in critical care as both offer the potential to enhance host defences, through different but complimentary mechanisms and may reduce subsequent infections and mortality. The SIGNET trial (randomized controlled factorial trial) is the largest, cr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Andrews PJ

更新日期：2010-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Here, we discuss recent work focused on the role of activating transcription factor 4 (ATF4) in skeletal muscle atrophy. RECENT FINDINGS:Muscle atrophy involves and requires widespread changes in skeletal muscle gene expression; however, the transcriptional regulatory proteins responsible for those c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Adams CM,Ebert SM,Dyle MC

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The obesity paradox is a highly controversial concept that may be attributed to methodological limitations related to its identification. One of the primary concerns is the use of BMI to define obesity. This index does not differentiate lean versus adipose tissue compartments (i.e. body composition) c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Prado CM,Gonzalez MC,Heymsfield SB

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the evidences for and against the different nutritional and nonnutritional therapeutic approaches for severe alcoholic steatohepatitis, based on data from randomized controlled trials, in order to answer the question posed in the title: 'more of the same or something new?'. RECENT FINDING...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Cabré E

更新日期：2008-09-01 00:00:00