Adipose tissue inflammation: novel insight into the role of macrophages and lymphocytes.

abstract：PURPOSE OF REVIEW:The role of calorie restriction in humans is controversial. Recently, new data in monkeys and humans have provided new insights into the potential role of calorie restriction in longevity. RECENT FINDINGS:A study in rhesus monkeys showed a reduction in aging-associated mortality. A number of controll...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Morley JE,Chahla E,Alkaade S

更新日期：2010-01-01 00:00:00

abstract：PURPOSE OF REVIEW:High-fat diets lead to obesity and increase the risk of developing insulin resistance and type 2 diabetes. Adipose tissue and skeletal muscle act as endocrine organs, and produce various cytokines that can potentially alter peripheral insulin sensitivity. The purpose of the present review is to briefl...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Stefanyk LE,Dyck DJ

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle metabolic energy, needed to maintain contractile activity, is mainly obtained from glucose and long-chain fatty acids. Recent studies have revealed a remarkable parallel between the regulation of uptake of glucose and fatty acids by muscle, in that each is mediated by sarcolemmal trans...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Glatz JF,Bonen A,Luiken JJ

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:A new nutrition-related risk assessment tool, the Geriatric Nutritional Risk Index (GNRI), has been recently proposed. The aim of this review is to summarize current evidences on the use of this tool with particular focus on the rationales of its application in elderly healthcare. RECENT FINDINGS:Str...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Cereda E,Pedrolli C

更新日期：2009-01-01 00:00:00

abstract：:Advances in separation science are leading to more sensitive and more specific analysis of the complex mixtures of metabolites, vitamins and nutrients found in biofluids. Recent developments include capillary electrokinetic separations such as capillary electrophoresis, and the linking of separation methods to new for...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Perrett D

更新日期：1998-09-01 00:00:00

abstract：:This review examines recent advances in the dietary modulation of gene expression in the gastrointestinal tract. We have chosen to concentrate on individual genes and examine what is known about their regulation, attempting to link different studies together. ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kelly EJ,Sanderson IR

更新日期：1999-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition is prevalent in critically ill patients and is linked to worse outcomes such as prolonged mechanical ventilation, length of intensive care unit (ICU) stay, and increased mortality. Therefore, nutritional therapy is important. However, it is often difficult to accurately identify those at ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dong V,Karvellas CJ

更新日期：2020-12-05 00:00:00

abstract：PURPOSE OF REVIEW:To understand the potential benefits of increased dietary protein during weight loss and the importance of distribution of high-quality protein at each meal. RECENT FINDINGS:Popular weight loss diets emphasize use of protein as a substitute for carbohydrates or fat to reduce insulin and minimize hung...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Devkota S,Layman DK

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:There is increased evidence of several impaired gastrointestinal functions with ageing. In the elderly, however, most gastrointestinal functions remain relatively intact because of the large reserve capacity of the intestine and the great secretion capacity of the pancreas. This review will focus on c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hébuterne X

更新日期：2003-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the interest of functional food in low-income countries by analyzing various necessary factors. RECENT FINDINGS:Being on a low income would appear to relate most often to an unbalanced diet, both qualitatively and quantitatively, which may be damaging to health in the long term. Most ch...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Das A,Chakraborty R

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been growing evidence that lifestyle factors may affect the health and lifespan of an individual by affecting telomere length. The purpose of this review was to highlight the importance of telomeres in human health and aging and to summarize possible lifestyle factors that may affect health ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Shammas MA

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Size at birth is critical in determining life expectancy with both small and large neonates at risk of shortened life spans. This review examines the hormonal and nutritional drivers of intrauterine growth with emphasis on the role of foetal hormones as nutritional signals in utero. RECENT FINDINGS:N...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sferruzzi-Perri AN,Vaughan OR,Forhead AJ,Fowden AL

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the recent advances in our understanding of fatty acids and lipids in paediatric nonalcoholic fatty liver disease (NAFLD) and their future implications. RECENT FINDINGS:Data have been accumulated to suggest that ceramides are the main drivers of hepatic insulin resistance in NAFLD, and in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Mann JP,Feldstein AE,Nobili V

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The inflammatory response is essential in the response to pathogens. TNF-alpha, IL-1 and IL-6 are key mediators of the response. They initiate metabolic changes to provide nutrients for the immune system, from host tissues. These changes include hyperlipidemia and increased gluconeogenesis. Insulin re...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Grimble RF

更新日期：2002-09-01 00:00:00

abstract：:New results on the physiological properties of conjugated linoleic acid have been published by several working groups, especially showing the effects of single conjugated linoleic acid isomers on carcinogenesis and body composition. Recently, other studies have shown that conjugated linoleic acid has an influence on d...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sébédio JL,Gnaedig S,Chardigny JM

更新日期：1999-11-01 00:00:00

abstract：:The most common methods for measuring the incorporation of tracer amino acids into tissue protein are the constant tracer infusion and the flooding dose. The flooding dose is an attractive method for measuring tissue protein synthesis because of its convenience and precision. A primary assumption of the method, that t...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Davis TA,Reeds PJ

更新日期：2001-01-01 00:00:00

abstract：:Studies of many different rodent models of muscle wasting have indicated that accelerated proteolysis via the ubiquitin-proteasome pathway is the principal cause of muscle atrophy induced by fasting, cancer cachexia, metabolic acidosis, denervation, disuse, diabetes, sepsis, burns, hyperthyroidism and excess glucocort...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Jagoe RT,Goldberg AL

更新日期：2001-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Muscular mitochondrial dysfunction, leading to the accumulation of fat in skeletal muscle, has been proposed to be involved in the development of type 2 diabetes mellitus. Here, we review human studies that investigated various aspects of mitochondrial function in relation to muscular insulin sensitiv...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Schrauwen-Hinderling VB,Roden M,Kooi ME,Hesselink MK,Schrauwen P

更新日期：2007-11-01 00:00:00

abstract：:The underlying causative agent in the majority of patients with chronic liver disease is ethanol; the rest of the cases are largely viral in aetiology (hepatitis B or C viruses). Nutrition supplementation improves the quality of life and decreases morbidity in chronic liver disease, but evidence that it prolongs long-...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Gopalan S,Saran S,Sengupta R

更新日期：2000-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The obesity paradox is a highly controversial concept that may be attributed to methodological limitations related to its identification. One of the primary concerns is the use of BMI to define obesity. This index does not differentiate lean versus adipose tissue compartments (i.e. body composition) c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Prado CM,Gonzalez MC,Heymsfield SB

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent conceptual frameworks and empirical findings addressing the role of prenatal stress and stress biology in the context of fetal programming of metabolic function and obesity risk. RECENT FINDINGS:The link between stress exposure and adverse health outcomes is well established. Grow...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Entringer S

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Folic acid is now considered an important functional food component: it lowers potentially toxic homocysteine, prevents birth defects and modulates the risk of several cancers. The complexity of interactions involved, however, means we still have much to learn about the role of folate and homocysteine...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lucock MD

更新日期：2006-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Poor vitamin K nutrition has recently been linked to several chronic diseases associated with abnormal calcification, which affect many elderly. To understand the impact of vitamin K nutrition on healthy aging it is necessary to assess both the determinants and the adequacy of vitamin K nutritional st...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Booth SL

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent literature suggests dietary glutamine supplementation may lower blood glucose in patients with type 1 diabetes (T1D), who have no residual insulin secretion. The mechanisms and potential relevance to the care of T1D remain unclear. RECENT FINDINGS:Glutamine is involved in multiple pathways inc...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Darmaun D,Torres-Santiago L,Mauras N

更新日期：2019-01-01 00:00:00

abstract：:Different types of dietary fatty acids have distinct, and sometimes opposing, effects on endothelial cell function. Long-chain n-3 polyunsaturated fatty acids from fish oil (eicosapentaenoic-acid-20:5n-3 and docosahexaenoic-acid-22:6n-3) attenuate cytokine-induced adhesion molecule expression (mRNA and protein) while ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wahle KW,Rotondo D

更新日期：1999-03-01 00:00:00

abstract：:Food products have variously been reported as causing, perpetuating or treating irritable bowel syndrome. The evidence for this is reviewed with regard to recent studies investigating symptom reporting, mono- and disaccharide malabsorption and probiotics. The development of objective measures remains an urgent priorit...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dunlop SP,Spiller RC

更新日期：2001-11-01 00:00:00

abstract：:Acute and chronic diseases are frequently characterized by alterations in energy metabolism that influence nutritional requirements and clinical care. Knowledge of the effect of disease on daily energy expenditure and its components is fundamental to understanding the impact of the disease process on energy balance. T...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Toth MJ

更新日期：2001-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to evaluate the most recent evidence for a role of antioxidant nutrients in the prevention or delay in progression of age-related macular degeneration (AMD), a major cause of visual impairment and blindness in the aging population. RECENT FINDINGS:Recent human stu...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Johnson EJ

更新日期：2010-01-01 00:00:00

abstract：:Nephrotic patients show various abnormalities in protein kinetics. Plasma albumin levels and the total plasma albumin pool are reduced. The rate of hepatic absolute and fractional albumin synthesis are increased. Transferrin synthesis is also increased. Fibrinogen levels are elevated in nephrotic syndrome because of a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Castellino P,Cataliotti A

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Oxidative stress plays a central role in the transition from simple steatosis to nonalcoholic steatohepatitis (NASH). An effective therapeutic strategy is to target reduction in oxidative stress in NASH patients. The aim of this review is to discuss the role of oxidative stress in NASH and biological ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Pacana T,Sanyal AJ

更新日期：2012-11-01 00:00:00