Of flux and flooding: the advantages and problems of different isotopic methods for quantifying protein turnover in vivo : II. Methods based on the incorporation of a tracer.

abstract：PURPOSE OF REVIEW:Vascular function is recognized as an early and integrative marker of cardiovascular disease. While there is consistent evidence that the quantity of dietary fat has significant effects on vascular function, the differential effects of individual fatty acids is less clear. This review summarizes recen...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lovegrove JA,Griffin BA

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Sarcopenia is a progressive generalized decline in skeletal muscle mass, strength, and function. This condition is highly prevalent in critically ill patients and is associated with poor outcomes in the ICU. In this review, we describe the use, evidence, and limitations of the most common validated im...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lopez-Ruiz A,Kashani K

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The review summarizes current knowledge and recent findings about how to practically apply medication in patients with dysphagia and how swallowing function may be positively or negatively affected by drugs. RECENT FINDINGS:Oropharyngeal dysphagia is a major health problem in older persons and was re...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wirth R,Dziewas R

更新日期：2019-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Here, we discuss recent work focused on the role of activating transcription factor 4 (ATF4) in skeletal muscle atrophy. RECENT FINDINGS:Muscle atrophy involves and requires widespread changes in skeletal muscle gene expression; however, the transcriptional regulatory proteins responsible for those c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Adams CM,Ebert SM,Dyle MC

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Infection and sepsis remain major challenges in the critically ill. How nutritional therapy can effect real clinical outcomes is not easily apparent from the clinical data. Despite reducing infectious incidence, many studies show little difference in meaningful clinical outcomes. RECENT FINDINGS:Conf...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Griffiths RD

更新日期：2003-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition and polypharmacy increase with age and polymorbidity and their relationship is based on a number of mechanisms. The occurrence of malnutrition in both in-patients and out-patients and its dependence on polymorbidity and age are well known, but the interrelation of polypharmacy and malnutr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Zadak Z,Hyspler R,Ticha A,Vlcek J

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Oxidative stress plays a central role in the transition from simple steatosis to nonalcoholic steatohepatitis (NASH). An effective therapeutic strategy is to target reduction in oxidative stress in NASH patients. The aim of this review is to discuss the role of oxidative stress in NASH and biological ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Pacana T,Sanyal AJ

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyspepsia is a common disorder that presents as persistent or recurrent abdominal pain or discomfort in the upper abdomen and originates from organic or functional causes. Heterogeneous disorders, physiopathological, psychosomatic, sociocultural, demographic and genetic components have a great impact ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： de Baptista GA

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The loss of skeletal muscle with injury or critical illness can be dramatic. This review emphasizes the importance of skeletal muscle as a metabolic reserve. Changes in protein metabolism with bed rest alone and during physiological stress are discussed. Nutritional and hormonal interventions that ame...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ferrando AA,Paddon-Jones D,Wolfe RR

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:There are concerns about the rising incidence of obesity in children and their acceptance of healthy foods. Many factors affect children's food acceptance, the most salient are those enabling early exposure to culturally appropriate foods in the weaning or pre-weaning period. Parents, however, have al...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Harris G

更新日期：2008-05-01 00:00:00

abstract：:The K vitamins, a group of napthoquinones, are required for the carboxylation of a limited number of proteins including the bone matrix protein osteocalcin. Vitamin K1 (phylloquinone) and vitamin K2 (menaquinones), differ regarding food source (green vegetables and fermented products, respectively), bioavailability an...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Zittermann A

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an objective and comprehensive review of the recent literature addressing the effects of sex on protein metabolism. We also evaluate whether these differences can be attributed to physiology or methodology. Because of the developmental changes in hormonal milieu and body composition that oc...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Markofski MM,Volpi E

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to emphasize the importance of malnutrition in frail institutionalized elderly and discuss recent interventions that have been shown to decrease its prevalence. RECENT FINDINGS:A Medline search was conducted from 1968 to 2007 under the search terms aging, nutrition, and nur...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Labossiere R,Bernard MA

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:There is increased evidence of several impaired gastrointestinal functions with ageing. In the elderly, however, most gastrointestinal functions remain relatively intact because of the large reserve capacity of the intestine and the great secretion capacity of the pancreas. This review will focus on c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hébuterne X

更新日期：2003-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Occlusions of central venous catheters in service are frequent, but the random nature of the problem has resulted in a piecemeal approach to solving it. The purpose of this review is to examine what is known from past and recent publications and to recommend strategies for future investigations. RECE...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hardy G,Ball P

更新日期：2005-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss transcriptional mechanisms regulating hepatic lipid metabolism. RECENT FINDINGS:Humans who are obese or have diabetes (NIDDM) or metabolic syndrome (MetS) have low blood and tissue levels of C20-22 polyunsaturated fatty acids (PUFAs). Although the impact of low C20-22 PUFAs on disease prog...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Jump DB

更新日期：2011-03-01 00:00:00

abstract：PURPOSE OF REVIEW:High-fat diets lead to obesity and increase the risk of developing insulin resistance and type 2 diabetes. Adipose tissue and skeletal muscle act as endocrine organs, and produce various cytokines that can potentially alter peripheral insulin sensitivity. The purpose of the present review is to briefl...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Stefanyk LE,Dyck DJ

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the recent findings on metabolic monitoring and possible beneficial effects of an adequate nutrition therapy, based on indirect calorimetry as the golden standard to predict energy expenditure. RECENT FINDINGS:in the last decades, major steps are taken in the field of metabolism and nutriti...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： De Waele E,Honoré PM,Malbrain MLNG

更新日期：2018-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition is prevalent in critically ill patients and is linked to worse outcomes such as prolonged mechanical ventilation, length of intensive care unit (ICU) stay, and increased mortality. Therefore, nutritional therapy is important. However, it is often difficult to accurately identify those at ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dong V,Karvellas CJ

更新日期：2020-12-05 00:00:00

abstract：PURPOSE OF REVIEW:Improving our understanding of factors driving fat gain in young children should increase our ability to manage the rising problem of obesity. Accordingly, studies associating timing of adiposity rebound with later obesity are reviewed. RECENT FINDINGS:Investigations in many countries have confirmed ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Taylor RW,Grant AM,Goulding A,Williams SM

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Leucine does not only serve as a substrate for protein synthesis but is also recognized as a potent signal nutrient that regulates protein metabolism. Accordingly, leucine supplementation has been suggested to develop muscle mass or prevent protein loss in several conditions characterized by muscle pr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Balage M,Dardevet D

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide guidance for investigators who are new to the field of DNA methylation analysis. RECENT FINDINGS:Epigenetics is the study of mitotically heritable alterations in gene expression potential that are not mediated by changes in DNA sequence. Recently, it has become clear that nutrition can aff...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Shen L,Waterland RA

更新日期：2007-09-01 00:00:00

abstract：:Despite the extensive current literature on ethics, very few publications have specifically addressed the ethical issues surrounding the provision of nutrition to perioperative patients. Four publications are particularly relevant and highly recommended [1-4]. This review is an attempt to draw attention to those ethic...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： MacFie J

更新日期：2000-01-01 00:00:00

abstract：:Milk is the only biomaterial that evolved under the Darwinian selective pressure to nourish growing mammals. The purpose of this article is to review the scientific research that is using new techniques of integrating biological sequence, structure and function, to understand the innovative biology underlying the prod...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： German JB,Dillard CJ,Ward RE

更新日期：2002-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The design and the development of functional foods is a key issue for bone health and a scientific challenge as well. As most studies have focused on calcium, and have paid less attention to other nutrients, our knowledge of the influence of nutrition on bone health remains limited. It has been well a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Davicco MJ,Wittrant Y,Coxam V

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Dietary fibers decrease risk of cardiovascular disease and obesity, but the most important mechanisms for fiber's protective properties are debated. The purpose of the review is to summarize the recent human studies that examine mechanisms how dietary fiber decreases risk of obesity-related disorders....

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dayib M,Larson J,Slavin J

更新日期：2020-11-01 00:00:00

abstract：PURPOSE OF REVIEW:A large percentage of older adults do not receive recommended amounts of many nutrients from food alone. Accordingly, the routine use of dietary supplements has become common among older persons. Although supplement use provides potential benefits by increasing nutrient intakes, there are potential dr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Walrand S

更新日期：2018-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steato hepatitis have an increasing prevalence among liver diseases. Overweight and obesity are frequently associated conditions in patients with fatty liver. Skeletal muscle mass depletion may also coexist with chronic liver disease even in ob...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Merli M,Lattanzi B,Aprile F

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Poor vitamin K nutrition has recently been linked to several chronic diseases associated with abnormal calcification, which affect many elderly. To understand the impact of vitamin K nutrition on healthy aging it is necessary to assess both the determinants and the adequacy of vitamin K nutritional st...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Booth SL

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to highlight recent research findings that advance our understanding of the relation between iron status and neural functioning. RECENT FINDINGS:Recent findings have helped to answer questions pertaining to the interrelationship of iron and neural functioning in three pri...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Murray-Kolb LE

更新日期：2013-11-01 00:00:00