Telomeres, lifestyle, cancer, and aging.

abstract：PURPOSE OF REVIEW:Metabolic toxicities in HIV patients are common and contribute to clinical status and long-term sequelae. Body fat mass alterations, of multifactorial causes, continue to occur, despite use of antiretroviral drugs associated with fewer metabolic side-effects. The role of HIV itself in the development ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Falutz J

更新日期：2011-05-01 00:00:00

abstract：:The underlying causative agent in the majority of patients with chronic liver disease is ethanol; the rest of the cases are largely viral in aetiology (hepatitis B or C viruses). Nutrition supplementation improves the quality of life and decreases morbidity in chronic liver disease, but evidence that it prolongs long-...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Gopalan S,Saran S,Sengupta R

更新日期：2000-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This article provides an overview of the most recent molecular and clinical outcomes of studies that investigate the effect of weight loss and calorie restriction on carbohydrate metabolism, obtained either by dieting or bariatric surgery. It will focus on aspects of carbohydrate metabolism related to...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Manco M,Mingrone G

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Intradialytic nutritional support has been used for more than 30 years both in critically ill patients with acute renal failure and during maintenance hemodialysis. Present knowledge allows better estimation of its metabolic and nutritional efficacy, as well its effect on patient outcome. RECENT FIND...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Cano NJ,Leverve XM

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review methods to measure the content and distribution of body fat or adipose tissue in humans are examined. The review particularly emphasizes methods to characterize regional fat distribution and ectopic fat (fat contained within other tissues) including specific applications and implication...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Goodpaster BH

更新日期：2002-09-01 00:00:00

abstract：:Antioxidant nutrients are important for limiting damaging oxidative reactions in cells, which may predispose to the development of major clinical conditions such as heart disease and cancer. There is great interest in the possibility that the antioxidant potential of plant-derived phenolic compounds, such as flavonoid...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Duthie G,Crozier A

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The function and use of vitamin D supplementation has become very controversial. This review attempts to provide a balanced perspective with respect to the experimental findings published in the past 18 months. RECENT FINDINGS:The recent contrasts between the Institute of Medicine (IOM) report and th...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hollis BW

更新日期：2011-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The pathogenesis of coronary heart disease is of multifactorial origin. Probably, not all risk factors are satisfactorily understood. This article outlines beneficial vitamin D effects on cardiac function and the vasculature. In addition, human data associating serum vitamin D metabolite levels or ora...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Zittermann A,Koerfer R

更新日期：2008-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Lipidomic profiling of biological samples is increasing in nutritional research applications. 'Lipidomic analyses' however can be quite variable in specific methods and the type of information about the specific lipids that is revealed. The lack of defined and simple terminology to describe aspects of...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Aristizabal Henao JJ,Bradley RM,Duncan RE,Stark KD

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:A large percentage of older adults do not receive recommended amounts of many nutrients from food alone. Accordingly, the routine use of dietary supplements has become common among older persons. Although supplement use provides potential benefits by increasing nutrient intakes, there are potential dr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Walrand S

更新日期：2018-11-01 00:00:00

abstract：:The intracellular signalling pathways controlling muscle protein synthesis and proteolysis are potential targets for anabolic/anti-catabolic therapy. In this review, we consider both the potentiation of the effect of anabolic hormones and suppression of the catabolic action of cytokines. Potential candidates, in parti...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Palmer RM,Thompson MG

更新日期：1999-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Preventing unintentional weight and muscle loss is of crucial importance to maintain the condition and well-being of patients with cancer, improve treatment response and tolerance, and prolong survival. Anabolic resistance might explain why some cancer patients do not respond to nutritional interventi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Engelen MP,van der Meij BS,Deutz NE

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is a progressive lung disease with a high prevalence of extrapulmonary manifestations and, frequently, cardiovascular comorbidity. Resveratrol is a food-derived compound with anti-inflammatory, antioxidant, metabolic and cardioprotective potential. Therefor...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Beijers RJHCG,Gosker HR,Schols AMWJ

更新日期：2018-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to examine the concept of anorexia of aging, including its complex pathophysiology and the multifaceted interventions required to prevent adverse health consequences from this geriatric syndrome. RECENT FINDINGS:Anorexia of aging is extremely common, occurring in up to 3...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sanford AM

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Early interventional trials reported improvements in cardiac and exercise outcomes with inorganic nitrate ingestion. The current review aims to provide a brief update of recent evidence regarding ergogenic and cardiovascular effects of dietary nitrate and practical recommendations. RECENT FINDINGS:Re...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kerley CP

更新日期：2017-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of the present review is to provide insights into the future therapeutic approaches to cancer-related muscle wasting that flow from the progressive knowledge of mechanisms regulating muscle mass in health and disease. RECENT FINDINGS:Cancer cachexia is a severely debilitating and life-threate...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Muscaritoli M,Bossola M,Bellantone R,Rossi Fanelli F

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this overview is to highlight the multiple ways in which oxidative stress could be exacerbating muscle wasting. Understanding these interactions in vivo will assist in identifying opportunities for more targeted therapies to reduce skeletal muscle wasting. RECENT FINDINGS:There are many ex...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Arthur PG,Grounds MD,Shavlakadze T

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Growth hormone is a powerful anabolic hormone necessary for normal growth, but its importance in maintaining the cellular and protein mass in adult life is still unclear. However, it is viewed as a drug capable of combating the tissue loss and some metabolic derangements of aging. Growth hormone exces...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Battezzati A,Bertoli S

更新日期：2005-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes some of the advances made over the past year in NMR-based metabolomics for the elucidation of known and unknown compounds, including new ways of how to combine this information with high-resolution mass spectrometry. RECENT FINDINGS:A new method allows the back-calculation of ma...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Bingol K,Brüschweiler R

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the recent advances in our understanding of fatty acids and lipids in paediatric nonalcoholic fatty liver disease (NAFLD) and their future implications. RECENT FINDINGS:Data have been accumulated to suggest that ceramides are the main drivers of hepatic insulin resistance in NAFLD, and in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Mann JP,Feldstein AE,Nobili V

更新日期：2017-03-01 00:00:00

abstract：:The liver plays a central role in the control of glucose production. It is also involved in the regulation of insulin secretion and sensitivity through neural pathways. This review will address recent developments in the mechanisms by which hepatic metabolism affects glucose homeostasis in health and disease. Oral glu...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Tappy L,Minehira K

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The obesity paradox is a highly controversial concept that may be attributed to methodological limitations related to its identification. One of the primary concerns is the use of BMI to define obesity. This index does not differentiate lean versus adipose tissue compartments (i.e. body composition) c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Prado CM,Gonzalez MC,Heymsfield SB

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide guidance for investigators who are new to the field of DNA methylation analysis. RECENT FINDINGS:Epigenetics is the study of mitotically heritable alterations in gene expression potential that are not mediated by changes in DNA sequence. Recently, it has become clear that nutrition can aff...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Shen L,Waterland RA

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine the stability and compatibility of histamine H2-receptor antagonists in parenteral nutrition admixtures in order to provide well tolerated and effective therapy. RECENT FINDINGS:Many stability investigations were carried out before 2005, but no critical appraisal of published data has been...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Puzovic M,Hardy G

更新日期：2007-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the recent findings on metabolic monitoring and possible beneficial effects of an adequate nutrition therapy, based on indirect calorimetry as the golden standard to predict energy expenditure. RECENT FINDINGS:in the last decades, major steps are taken in the field of metabolism and nutriti...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： De Waele E,Honoré PM,Malbrain MLNG

更新日期：2018-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity is associated with low-grade chronic inflammation in adipose tissue. This review presents an update on human and rodent studies analyzing the nature of fat-infiltrating immune cells, the time course of adipose tissue infiltration and underlying mechanisms. RECENT FINDINGS:Intensive studies in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sell H,Eckel J

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Poor vitamin K nutrition has recently been linked to several chronic diseases associated with abnormal calcification, which affect many elderly. To understand the impact of vitamin K nutrition on healthy aging it is necessary to assess both the determinants and the adequacy of vitamin K nutritional st...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Booth SL

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The concentrations of plasma-free amino acids, such as branched-chain amino acids and aromatic amino acids, are associated with visceral obesity, insulin resistance, and the future development of diabetes and cardiovascular diseases. This review discusses recent progress in the early assessment of the...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Nagao K,Yamakado M

更新日期：2016-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Until relatively recently, the only significant source of lactoferrin in the diet was human lactoferrin, provided in breast milk. Today, however, bovine lactoferrin, isolated by dairy technology, as well as recombinant human lactoferrin are commercially available and can be added to foods and clinical...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lönnerdal B

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Muscular mitochondrial dysfunction, leading to the accumulation of fat in skeletal muscle, has been proposed to be involved in the development of type 2 diabetes mellitus. Here, we review human studies that investigated various aspects of mitochondrial function in relation to muscular insulin sensitiv...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Schrauwen-Hinderling VB,Roden M,Kooi ME,Hesselink MK,Schrauwen P

更新日期：2007-11-01 00:00:00