Therapy of muscle wasting in cancer: what is the future?

abstract：PURPOSE OF REVIEW:Muscle protein synthesis (MPS) and muscle protein breakdown are simultaneous ongoing processes. Here, we examine evidence for how protein quality can affect exercise-induced muscle protein anabolism or protein balance (MPS minus muscle protein breakdown). Evidence is highlighted showing differences in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Tang JE,Phillips SM

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The speed of dietary protein digestion influences postprandial amino acid availability which is crucial for improving altered anabolic response of skeletal muscle one feature of sarcopenia during aging. RECENT FINDINGS:By analogy with carbohydrate and in reference to their absorption rate, dietary pr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Boirie Y,Guillet C

更新日期：2018-01-01 00:00:00

abstract：:Home artificial nutrition is a mature technology that has been with us for over a quarter of a century. Its use appears to be more widespread in the USA than in other western countries. Issues of outcome, ethics, and quality of life are increasingly important. Complications continue to be reported, some newly recogniz...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lipman TO

更新日期：1999-09-01 00:00:00

abstract：:Laboratory methods for the measurement of micronutrients are usually based upon determinations in the peripheral blood. Most are relatively insensitive, but can screen for impending acute deficiency or toxicity. The metabolic responses to disease, injury and infection may alter the laboratory findings independently of...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fell GS,Talwar D

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a need to develop a screening tool to assist clinical staff in deciding whether or not a patient in the ICU should be given nutrition support. The purpose of this review is to analyze the recent randomized trials in this context. RECENT FINDINGS:Five trials describe the effect of early suppl...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kondrup J

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide guidance for investigators who are new to the field of DNA methylation analysis. RECENT FINDINGS:Epigenetics is the study of mitotically heritable alterations in gene expression potential that are not mediated by changes in DNA sequence. Recently, it has become clear that nutrition can aff...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Shen L,Waterland RA

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The function and use of vitamin D supplementation has become very controversial. This review attempts to provide a balanced perspective with respect to the experimental findings published in the past 18 months. RECENT FINDINGS:The recent contrasts between the Institute of Medicine (IOM) report and th...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hollis BW

更新日期：2011-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The intake of water and electrolytes is inseparable from the ingestion of nutrients by normal or artificial means. Recent reports have agreed in criticizing the poor standards of practice and of training in the management of fluid and electrolyte balance, resulting in a large amount of avoidable morbi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Allison SP,Lobo DN

更新日期：2004-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyspepsia is a common disorder that presents as persistent or recurrent abdominal pain or discomfort in the upper abdomen and originates from organic or functional causes. Heterogeneous disorders, physiopathological, psychosomatic, sociocultural, demographic and genetic components have a great impact ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： de Baptista GA

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The design and the development of functional foods is a key issue for bone health and a scientific challenge as well. As most studies have focused on calcium, and have paid less attention to other nutrients, our knowledge of the influence of nutrition on bone health remains limited. It has been well a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Davicco MJ,Wittrant Y,Coxam V

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Randomized controlled trials can be difficult to conduct in critically ill patients and may not always be the most appropriate type of study. Cohort studies can provide valuable information in large complete populations of patients without strict exclusion criteria and without the need for informed co...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Vincent JL,Preiser JC

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steato hepatitis have an increasing prevalence among liver diseases. Overweight and obesity are frequently associated conditions in patients with fatty liver. Skeletal muscle mass depletion may also coexist with chronic liver disease even in ob...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Merli M,Lattanzi B,Aprile F

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Postoperative complications in gastrointestinal elective surgery have been described as low. In certain circumstances, however, such as those including high-risk patients, the incidence is higher. In such situations, bacteremia and infectious complications may be caused by translocation of either gast...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Correia MI,Nicoli JR

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide a concise overview of the polyphenol curcumin for improving arterial health, specifically endothelial function and arterial stiffness, to reduce cardiovascular disease (CVD) risk and to highlight potential mechanisms of action by which curcumin may improve arte...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fleenor BS,Carlini NA,Campbell MS

更新日期：2019-11-01 00:00:00

abstract：:Nephrotic patients show various abnormalities in protein kinetics. Plasma albumin levels and the total plasma albumin pool are reduced. The rate of hepatic absolute and fractional albumin synthesis are increased. Transferrin synthesis is also increased. Fibrinogen levels are elevated in nephrotic syndrome because of a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Castellino P,Cataliotti A

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:A compromised autophagy is associated with the onset of obesity, type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative diseases. Our aim is to review the potential role of ghrelin, a gut hormone involved in energy homeostasis, in the regulation of autophagy. RECENT F...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ezquerro S,Frühbeck G,Rodríguez A

更新日期：2017-09-01 00:00:00

abstract：:The problem with any attempt to feed patients in multiple organ failure is that, because of an ongoing inflammatory process, the conventional techniques of supplying energy and protein do not maintain lean tissue mass. In addition, the conventional markers of nutritional status, both anthropometric (body mass and comp...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Campbell IT

更新日期：1998-03-01 00:00:00

abstract：:Despite a large number of published randomized prospective controlled clinical trials the indications for perioperative parenteral and enteral nutrition support remain controversial. This article reviews the reports of several recently published consensus conference reports and prospective randomized controlled trials...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Satyanarayana R,Klein S

更新日期：1998-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The mortality and morbidity associated with severe acute malnutrition (SAM) remain high. A summary of recent studies that are of interest to clinicians treating children with SAM is provided. RECENT FINDINGS:Three important themes emerged in 2015: the use of anthropometry in the diagnosis of SAM and ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Nel ED

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The high sugar content of regular soft drinks brought up discussions on their influence on energy balance and body weight especially in childhood and adolescence. This review examines the evidence for a causal relationship between soft drink consumption and excess weight gain in childhood and identifi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Libuda L,Kersting M

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The data indicating that alcohol is an important factor increasing the risk to develop gastrointestinal cancer are consolidating. The purpose of this review is to summarize current evidence. RECENT FINDINGS:Acetaldehyde is the first metabolite of ethanol metabolism and has direct carcinogenic and mut...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Haas SL,Ye W,Löhr JM

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent advances pertaining to the mechanisms regulating brain docosahexaenoic acid (DHA) uptake. DHA is an omega-3 polyunsaturated fatty acid highly enriched in neuronal membranes and it is implicated in several important neurological processes. However, DHA synthesis is extremely limited...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Chouinard-Watkins R,Lacombe RJS,Bazinet RP

更新日期：2018-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Products of infection, ischemia, and injury stimulate the innate immune system to release proinflammatory cytokines, which act locally to activate specific cellular immune responses and initiate recovery. In pathological cases, however, cytokines are released systemically, resulting in progressive tis...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Friedman SG,Czura CJ,Tracey KJ

更新日期：2003-05-01 00:00:00

abstract：PURPOSE OF REVIEW:A new nutrition-related risk assessment tool, the Geriatric Nutritional Risk Index (GNRI), has been recently proposed. The aim of this review is to summarize current evidences on the use of this tool with particular focus on the rationales of its application in elderly healthcare. RECENT FINDINGS:Str...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Cereda E,Pedrolli C

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Investigations into the regulation of muscle protein synthesis (MPS) are a cornerstone of understanding the control of muscle mass. Rates of MPS are finely tuned according to levels of activity, nutrient availability and health status. For instance, rates of MPS are positively regulated by exercise an...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Phillips BE,Hill DS,Atherton PJ

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine the results of new investigations that look at the efficacy of nutrient/training strategies on metabolism and athletic performance. RECENT FINDINGS:'Dietary periodization' involves the manipulation of macronutrient intake in association with changes in physical training. Such interventions...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Burke LM,Hawley JA

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review provides an overview of the different dietary quality indices in use. In the first decades, most indices were developed for the general adult population and were based on the American dietary guidelines and the Mediterranean diet. This review focuses on new, other dietary quality in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fransen HP,Ocké MC

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is a progressive lung disease with a high prevalence of extrapulmonary manifestations and, frequently, cardiovascular comorbidity. Resveratrol is a food-derived compound with anti-inflammatory, antioxidant, metabolic and cardioprotective potential. Therefor...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Beijers RJHCG,Gosker HR,Schols AMWJ

更新日期：2018-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular function is recognized as an early and integrative marker of cardiovascular disease. While there is consistent evidence that the quantity of dietary fat has significant effects on vascular function, the differential effects of individual fatty acids is less clear. This review summarizes recen...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lovegrove JA,Griffin BA

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the recent findings on metabolic monitoring and possible beneficial effects of an adequate nutrition therapy, based on indirect calorimetry as the golden standard to predict energy expenditure. RECENT FINDINGS:in the last decades, major steps are taken in the field of metabolism and nutriti...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： De Waele E,Honoré PM,Malbrain MLNG

更新日期：2018-03-01 00:00:00