Advances in separation science relating to clinical nutrition.

Abstract:

:Advances in separation science are leading to more sensitive and more specific analysis of the complex mixtures of metabolites, vitamins and nutrients found in biofluids. Recent developments include capillary electrokinetic separations such as capillary electrophoresis, and the linking of separation methods to new forms of mass spectrometry.

authors

Perrett D

doi

10.1097/00075197-199809000-00012

subject

Has Abstract

pub_date

1998-09-01 00:00:00

pages

433-7

issue

5

eissn

1363-1950

issn

1473-6519

journal_volume

1

pub_type

杂志文章,评审
  • Gut changes attributed to ageing: effects on intestinal microflora.

    abstract:PURPOSE OF REVIEW:There is increased evidence of several impaired gastrointestinal functions with ageing. In the elderly, however, most gastrointestinal functions remain relatively intact because of the large reserve capacity of the intestine and the great secretion capacity of the pancreas. This review will focus on c...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200301000-00008

    authors: Hébuterne X

    更新日期:2003-01-01 00:00:00

  • Clogbusting: time for a concerted approach to catheter occlusions?

    abstract:PURPOSE OF REVIEW:Occlusions of central venous catheters in service are frequent, but the random nature of the problem has resulted in a piecemeal approach to solving it. The purpose of this review is to examine what is known from past and recent publications and to recommend strategies for future investigations. RECE...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/01.mco.0000165006.39449.1f

    authors: Hardy G,Ball P

    更新日期:2005-05-01 00:00:00

  • Nutritional and metabolic advances in inflammatory bowel disease.

    abstract::Crude measurements of nutritional status, such as body weight, are inadequate to assess the severity and consequence of malnutrition among inflammatory bowel disease patients. Functional deficiency resulting in osteopenia and muscle weakness have been demonstrated in these patients when compared to controls. Manipulat...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-199809000-00002

    authors: Burke A,Lichtenstein GR,Rombeau JL

    更新日期:1998-09-01 00:00:00

  • Nutritional issues in irritable bowel syndrome.

    abstract::Food products have variously been reported as causing, perpetuating or treating irritable bowel syndrome. The evidence for this is reviewed with regard to recent studies investigating symptom reporting, mono- and disaccharide malabsorption and probiotics. The development of objective measures remains an urgent priorit...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200111000-00013

    authors: Dunlop SP,Spiller RC

    更新日期:2001-11-01 00:00:00

  • Vitamin K status in the elderly.

    abstract:PURPOSE OF REVIEW:Poor vitamin K nutrition has recently been linked to several chronic diseases associated with abnormal calcification, which affect many elderly. To understand the impact of vitamin K nutrition on healthy aging it is necessary to assess both the determinants and the adequacy of vitamin K nutritional st...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e328011ab5f

    authors: Booth SL

    更新日期:2007-01-01 00:00:00

  • Age-related macular degeneration and antioxidant vitamins: recent findings.

    abstract:PURPOSE OF REVIEW:The purpose of the present review is to evaluate the most recent evidence for a role of antioxidant nutrients in the prevention or delay in progression of age-related macular degeneration (AMD), a major cause of visual impairment and blindness in the aging population. RECENT FINDINGS:Recent human stu...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32833308ff

    authors: Johnson EJ

    更新日期:2010-01-01 00:00:00

  • Amino acid metabolism in liver disease.

    abstract::The impairment of transsulphuration during methionine degradation in hepatic failure can be counteracted by treatment with S-adenosylmethionine. Regarding the pathogenesis of hepatic encephalopathy, no convincing evidence exists for tryptophan, glutamine or glutamate being involved. Portal-systemic shunting-induced hy...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-199901000-00009

    authors: Holm E,Sedlaczek O,Grips E

    更新日期:1999-01-01 00:00:00

  • Dietary approaches to assessing iron-related nutrition.

    abstract:PURPOSE OF REVIEW:Both dietary and nondietary factors contribute to iron deficiency, the most common nutritional deficiency worldwide. Identifying dietary factors associated with iron deficiency is challenging due to the number of components in food affecting iron absorption. This review describes recent advances in di...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e328364f382

    authors: Beck KL,Heath AL

    更新日期:2013-11-01 00:00:00

  • Angiotensin II as candidate of cardiac cachexia.

    abstract:PURPOSE OF REVIEW:Congestive heart failure is increasing in prevalence and represents a major public health problem. The syndrome of advanced heart failure often includes muscle wasting, commonly termed cardiac cachexia, which is a predictor of poor outcome. Mechanisms of cardiac cachexia are poorly understood, but the...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/01.mco.0000222103.29009.70

    authors: Delafontaine P,Akao M

    更新日期:2006-05-01 00:00:00

  • Genetic and metabolic determinants of human epigenetic variation.

    abstract:PURPOSE OF REVIEW:Epigenetics has emerged in recent years as one of the most important biological mechanisms linking exposures across the life course to long-term health. This article reviews recent developments in our understanding of the metabolic and genetic determinants of epigenetic variation in human populations....

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000194

    authors: Haggarty P

    更新日期:2015-07-01 00:00:00

  • Impact of stress and stress physiology during pregnancy on child metabolic function and obesity risk.

    abstract:PURPOSE OF REVIEW:To summarize recent conceptual frameworks and empirical findings addressing the role of prenatal stress and stress biology in the context of fetal programming of metabolic function and obesity risk. RECENT FINDINGS:The link between stress exposure and adverse health outcomes is well established. Grow...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32835e8d80

    authors: Entringer S

    更新日期:2013-05-01 00:00:00

  • Categorizing and qualifying nutritional lipidomic data: defining brutto, medio, genio, and infinio lipid species within macrolipidomics and microlipidomics.

    abstract:PURPOSE OF REVIEW:Lipidomic profiling of biological samples is increasing in nutritional research applications. 'Lipidomic analyses' however can be quite variable in specific methods and the type of information about the specific lipids that is revealed. The lack of defined and simple terminology to describe aspects of...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000495

    authors: Aristizabal Henao JJ,Bradley RM,Duncan RE,Stark KD

    更新日期:2018-09-01 00:00:00

  • The role of L-arginine following trauma and blood loss.

    abstract:PURPOSE OF REVIEW:Vascular endothelial cells control vascular smooth muscle tone via the release of nitric oxide. Following adverse circulatory conditions, namely trauma and hemorrhage, endothelial cell dysfunction occurs, leading to a decrease in the release of endothelium-derived nitric oxide, which contributes to fu...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e328011bb1b

    authors: Loehe F,Bruns CJ,Nitsch SM,Angele MK

    更新日期:2007-01-01 00:00:00

  • Vitamin E: absorption, plasma transport and cell uptake.

    abstract:PURPOSE OF REVIEW:Large-scale clinical trials have failed to demonstrate a benefit for vitamin E supplementation in cardiovascular prevention. This contrasts with previous epidemiological studies indicating that individuals with high vitamin E status benefit from protection against chronic illnesses, including cardiova...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200503000-00005

    authors: Hacquebard M,Carpentier YA

    更新日期:2005-03-01 00:00:00

  • Neural systems controlling food intake and energy balance in the modern world.

    abstract:PURPOSE OF REVIEW:Obesity continues to increase around the globe, and creates a major health problem because of its comorbidities such as diabetes and cardiovascular disease. Considering that the major cause of most human obesities is the modern lifestyle in a rapidly changing environment, this suggests that the battle...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200311000-00002

    authors: Berthoud HR

    更新日期:2003-11-01 00:00:00

  • Taurine and skeletal muscle function.

    abstract:PURPOSE OF REVIEW:To discuss the recent work examining the importance of taurine in skeletal muscle and outline the discrepancy that exists between research findings in rodent vs. human skeletal muscle. RECENT FINDINGS:There is clear evidence that a normal taurine level is important for the normal functioning of skele...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000135

    authors: Spriet LL,Whitfield J

    更新日期:2015-01-01 00:00:00

  • Stearoyl-coenzyme A desaturase 1, sterol regulatory element binding protein-1c and peroxisome proliferator-activated receptor-alpha: independent and interactive roles in the regulation of lipid metabolism.

    abstract:PURPOSE OF REVIEW:With the increasing incidence of obesity today, related complications such as diabetes, insulin resistance and hepatic steatosis are also becoming major concerns. Since these conditions share a common factor, aberrations in lipid metabolism, understanding the molecular changes that lead to abnormal li...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/01.mco.0000214564.59815.af

    authors: Sampath H,Ntambi JM

    更新日期:2006-03-01 00:00:00

  • Polyunsaturated fatty acids, membrane function and metabolic diseases such as diabetes and obesity.

    abstract::Lipids play an extraordinary range of roles in normal and deranged metabolism. In diabetes and obesity, lipids have often been seen just as impacting on the energy balance equation. New data are extending our understanding of how lipid subclasses influence carbohydrate and lipid metabolism at multiple control points: ...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-199811000-00014

    authors: Storlien LH,Hulbert AJ,Else PL

    更新日期:1998-11-01 00:00:00

  • Nutritional assessment in the hospitalized patient.

    abstract:PURPOSE OF REVIEW:Malnutrition is highly prevalent in hospitalized patients. Despite this, it is not routinely assessed in most hospitals worldwide. One of the reasons that might explain this fact is that there is no gold-standard nutritional assessment tool, and much has been written advocating this or that technique....

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200309000-00006

    authors: Waitzberg DL,Correia MI

    更新日期:2003-09-01 00:00:00

  • New data and new concepts on the role of the liver in glucose homeostasis.

    abstract::The liver plays a central role in the control of glucose production. It is also involved in the regulation of insulin secretion and sensitivity through neural pathways. This review will address recent developments in the mechanisms by which hepatic metabolism affects glucose homeostasis in health and disease. Oral glu...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200107000-00005

    authors: Tappy L,Minehira K

    更新日期:2001-07-01 00:00:00

  • New lipids in enteral feeding.

    abstract:PURPOSE OF REVIEW:Lipid sources for enteral nutrition continue to be an exciting area of investigation. It is timely to review recent developments which have largely contributed to thrust enteral feeding into a new era. RECENT FINDINGS:Although much more research needs to be done, there is a better understanding of th...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200403000-00003

    authors: Roy CC,Bouthillier L,Seidman E,Levy E

    更新日期:2004-03-01 00:00:00

  • Bedside ultrasound measurement of skeletal muscle.

    abstract:PURPOSE OF REVIEW:Skeletal muscle and lean body mass may be vital to prognosis and functional recovery in chronic and acute illness, particularly in conditions in which muscle atrophy is prevalent. Ultrasound provides a precise and expedient method to measure muscle mass and changes in skeletal muscle at the bedside. ...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000088

    authors: Mourtzakis M,Wischmeyer P

    更新日期:2014-09-01 00:00:00

  • Anabolic hormones in critically ill patients.

    abstract::Critical illness and severe injury induce a number of neuroendocrine changes that initially enhance survival. However, for skeletal muscle, the hormonal environment is such that accelerated catabolism predominates. The prevailing hypercortisolemia is exacerbated by a resistance to or decreased production of anabolic h...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-199903000-00014

    authors: Ferrando AA

    更新日期:1999-03-01 00:00:00

  • Severe acute malnutrition.

    abstract:PURPOSE OF REVIEW:The mortality and morbidity associated with severe acute malnutrition (SAM) remain high. A summary of recent studies that are of interest to clinicians treating children with SAM is provided. RECENT FINDINGS:Three important themes emerged in 2015: the use of anthropometry in the diagnosis of SAM and ...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000269

    authors: Nel ED

    更新日期:2016-05-01 00:00:00

  • Iron and brain functions.

    abstract:PURPOSE OF REVIEW:The purpose of this study is to highlight recent research findings that advance our understanding of the relation between iron status and neural functioning. RECENT FINDINGS:Recent findings have helped to answer questions pertaining to the interrelationship of iron and neural functioning in three pri...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e3283653ef8

    authors: Murray-Kolb LE

    更新日期:2013-11-01 00:00:00

  • Exercise and insulin increase muscle fatty acid uptake by recruiting putative fatty acid transporters to the sarcolemma.

    abstract:PURPOSE OF REVIEW:Skeletal muscle metabolic energy, needed to maintain contractile activity, is mainly obtained from glucose and long-chain fatty acids. Recent studies have revealed a remarkable parallel between the regulation of uptake of glucose and fatty acids by muscle, in that each is mediated by sarcolemmal trans...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200207000-00003

    authors: Glatz JF,Bonen A,Luiken JJ

    更新日期:2002-07-01 00:00:00

  • Nutrient regulation of intestinal gene expression.

    abstract::This review examines recent advances in the dietary modulation of gene expression in the gastrointestinal tract. We have chosen to concentrate on individual genes and examine what is known about their regulation, attempting to link different studies together. ...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-199907000-00009

    authors: Kelly EJ,Sanderson IR

    更新日期:1999-07-01 00:00:00

  • Fructooligosaccharides and appetite.

    abstract:PURPOSE OF REVIEW:Dietary fiber may play a role in obesity prevention through reduction of body weight and control of appetite, however, not all fibers are created equally, and characteristics of fiber such as viscosity, fermentability and solubility may affect appetite differently. RECENT FINDINGS:Although early stud...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000502

    authors: Korczak R,Slavin JL

    更新日期:2018-09-01 00:00:00

  • Long-term effects of leucine supplementation on body composition.

    abstract:PURPOSE OF REVIEW:Leucine does not only serve as a substrate for protein synthesis but is also recognized as a potent signal nutrient that regulates protein metabolism. Accordingly, leucine supplementation has been suggested to develop muscle mass or prevent protein loss in several conditions characterized by muscle pr...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e328336f6b8

    authors: Balage M,Dardevet D

    更新日期:2010-05-01 00:00:00

  • The acute and long-term effects of dietary fatty acids on vascular function in health and disease.

    abstract:PURPOSE OF REVIEW:Vascular function is recognized as an early and integrative marker of cardiovascular disease. While there is consistent evidence that the quantity of dietary fat has significant effects on vascular function, the differential effects of individual fatty acids is less clear. This review summarizes recen...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32835c5f29

    authors: Lovegrove JA,Griffin BA

    更新日期:2013-03-01 00:00:00