Long-term effects of leucine supplementation on body composition.

abstract：PURPOSE OF REVIEW:With the increasing incidence of obesity today, related complications such as diabetes, insulin resistance and hepatic steatosis are also becoming major concerns. Since these conditions share a common factor, aberrations in lipid metabolism, understanding the molecular changes that lead to abnormal li...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sampath H,Ntambi JM

更新日期：2006-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The gastrointestinal tract plays an important role in the maintenance of fluid and electrolyte balance, and its diseases cause disturbances in that balance. Conversely, fluid and electrolyte disorders may disturb gastrointestinal function. The purpose of this review is to highlight some recent literat...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Macafee DA,Allison SP,Lobo DN

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been growing evidence that lifestyle factors may affect the health and lifespan of an individual by affecting telomere length. The purpose of this review was to highlight the importance of telomeres in human health and aging and to summarize possible lifestyle factors that may affect health ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Shammas MA

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The intake of water and electrolytes is inseparable from the ingestion of nutrients by normal or artificial means. Recent reports have agreed in criticizing the poor standards of practice and of training in the management of fluid and electrolyte balance, resulting in a large amount of avoidable morbi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Allison SP,Lobo DN

更新日期：2004-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The loss of skeletal muscle with injury or critical illness can be dramatic. This review emphasizes the importance of skeletal muscle as a metabolic reserve. Changes in protein metabolism with bed rest alone and during physiological stress are discussed. Nutritional and hormonal interventions that ame...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ferrando AA,Paddon-Jones D,Wolfe RR

更新日期：2006-07-01 00:00:00

abstract：:Plant sterols have recently been recommended by the National Cholesterol Education Panel for use with the more traditional approaches of limiting saturated fat and cholesterol intakes, maintaining a healthy body weight and engaging in regular exercise, as a non-pharmacological approach to reduce low-density lipoprotei...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lichtenstein AH

更新日期：2002-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Glutamine and arginine are conditionally essential amino acids because depletion occurs in stressed conditions. Intravenous glutamine supplementation reduces morbidity and mortality in critically ill patients fed parenterally. In surgical patients, arginine-enriched diets have beneficial effects, but ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Coëffier M,Déchelotte P

更新日期：2010-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide guidance for investigators who are new to the field of DNA methylation analysis. RECENT FINDINGS:Epigenetics is the study of mitotically heritable alterations in gene expression potential that are not mediated by changes in DNA sequence. Recently, it has become clear that nutrition can aff...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Shen L,Waterland RA

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Insulin resistance is an important risk factor for metabolic diseases such as type 2 diabetes, cardiovascular disease and certain cancers. A common characteristic of strategies that improve insulin sensitivity involves the activation of the energy sensing enzyme of the cell, AMP-activated protein kina...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Smith BK,Steinberg GR

更新日期：2017-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The obesity paradox is a highly controversial concept that may be attributed to methodological limitations related to its identification. One of the primary concerns is the use of BMI to define obesity. This index does not differentiate lean versus adipose tissue compartments (i.e. body composition) c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Prado CM,Gonzalez MC,Heymsfield SB

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide a concise overview of the polyphenol curcumin for improving arterial health, specifically endothelial function and arterial stiffness, to reduce cardiovascular disease (CVD) risk and to highlight potential mechanisms of action by which curcumin may improve arte...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fleenor BS,Carlini NA,Campbell MS

更新日期：2019-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the recent work on potential mechanisms underlying a paradoxical positive association between the consumption of non-nutritive sweeteners (NNS) and weight gain. RECENT FINDINGS:Several potential mechanisms, not mutually exclusive, are hypothesized. First, by dissociating sweetness from calo...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Pepino MY,Bourne C

更新日期：2011-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonalcoholic fatty liver disease (NAFLD) is the liver epidemic of our time. Diet strongly influences its development and should be a component of any treatment plan. It is crucial to standardize diet recommendations in an evidence-based manner. RECENT FINDINGS:Calorie restriction per se seems benefic...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Carvalhana S,Machado MV,Cortez-Pinto H

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:In recent years, the lower costs of arrays and sequencing technologies, and the better availability of data from genome-wide association studies (GWASs) have led to more reports on genetic factors that are associated with bone health. However, there remains the need for a summary of the newly identifi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lovšin N,Zupan J,Marc J

更新日期：2018-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent epidemiologic and intervention studies addressing the impact of hyperglycemia on morbidity and mortality in critically ill patients. It also discusses a growing body of literature examining why elevated blood glucose occurs in hospitalized patients without previously recogn...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Falciglia M

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The concentrations of plasma-free amino acids, such as branched-chain amino acids and aromatic amino acids, are associated with visceral obesity, insulin resistance, and the future development of diabetes and cardiovascular diseases. This review discusses recent progress in the early assessment of the...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Nagao K,Yamakado M

更新日期：2016-09-01 00:00:00

abstract：:Arginine is a non-essential amino acid in mammals as judged from nitrogen balance study. Citrulline is synthesized from glutamate in the small intestine, whilst kidneys and some other tissues convert citrulline to arginine. Ornithine transcarbamylase and carbamylphosphate synthetase are expressed in liver and small in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wakabayashi Y

更新日期：1998-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent advances in the development of new therapeutic strategies combining conventional adjuvant radio/chemotherapy with nutritional manipulations with n-3 polyunsaturated fatty acids (PUFAs) are presented. RECENT FINDINGS:Studies in cell culture and tumour-bearing animals have reported the ability o...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dupertuis YM,Meguid MM,Pichard C

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze current evidence for the posology and pharmacokinetics of selenium supplementation in the critically ill. RECENT FINDINGS:Antioxidants and especially high-dose parenteral selenium may be associated with a significant reduction in mortality among critically ill patients with systemic inflam...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Manzanares W,Hardy G

更新日期：2009-05-01 00:00:00

abstract：:Lipids play an extraordinary range of roles in normal and deranged metabolism. In diabetes and obesity, lipids have often been seen just as impacting on the energy balance equation. New data are extending our understanding of how lipid subclasses influence carbohydrate and lipid metabolism at multiple control points: ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Storlien LH,Hulbert AJ,Else PL

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Overweight and obesity represent a significant health burden during pregnancy, placing women and their infants at increased risk of adverse health outcomes. Although there is considerable observational literature describing the effect of gestational weight gain in pregnancy, research efforts have focu...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dodd JM,O'Brien CM,Grivell RM

更新日期：2015-05-01 00:00:00

abstract：:Despite a large number of published randomized prospective controlled clinical trials the indications for perioperative parenteral and enteral nutrition support remain controversial. This article reviews the reports of several recently published consensus conference reports and prospective randomized controlled trials...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Satyanarayana R,Klein S

更新日期：1998-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity continues to increase around the globe, and creates a major health problem because of its comorbidities such as diabetes and cardiovascular disease. Considering that the major cause of most human obesities is the modern lifestyle in a rapidly changing environment, this suggests that the battle...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Berthoud HR

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Oxidative stress plays a central role in the transition from simple steatosis to nonalcoholic steatohepatitis (NASH). An effective therapeutic strategy is to target reduction in oxidative stress in NASH patients. The aim of this review is to discuss the role of oxidative stress in NASH and biological ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Pacana T,Sanyal AJ

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Fructose malabsorption is associated with gastrointestinal symptoms. This review examines new findings on the physiology, assessment and therapy of fructose malabsorption in functional gastrointestinal disorders. RECENT FINDINGS:Additional GLUT transport mechanisms that regulate fructose absorption m...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Putkonen L,Yao CK,Gibson PR

更新日期：2013-07-01 00:00:00

abstract：:Nephrotic patients show various abnormalities in protein kinetics. Plasma albumin levels and the total plasma albumin pool are reduced. The rate of hepatic absolute and fractional albumin synthesis are increased. Transferrin synthesis is also increased. Fibrinogen levels are elevated in nephrotic syndrome because of a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Castellino P,Cataliotti A

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The low FODMAP diet is now recognized as first-line therapy for treatment of irritable bowel syndrome (IBS) symptoms including abdominal pain, gas, bloating, diarrhea and or constipation. This information must be disseminated for application to clinical practice. RECENT FINDINGS:There are many people...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ireton-Jones C

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition is prevalent in critically ill patients and is linked to worse outcomes such as prolonged mechanical ventilation, length of intensive care unit (ICU) stay, and increased mortality. Therefore, nutritional therapy is important. However, it is often difficult to accurately identify those at ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dong V,Karvellas CJ

更新日期：2020-12-05 00:00:00

abstract：PURPOSE OF REVIEW:Obesity is associated with low-grade chronic inflammation in adipose tissue. This review presents an update on human and rodent studies analyzing the nature of fat-infiltrating immune cells, the time course of adipose tissue infiltration and underlying mechanisms. RECENT FINDINGS:Intensive studies in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sell H,Eckel J

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Metabolic syndrome (MetS) is associated with increased risk of obesity, type 2 diabetes mellitus and cardiovascular diseases. MetS prevalence has been associated with diet inadequacy. Conversely, the cumulative incidence of MetS has been inversely associated with a Mediterranean-style diet that includ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Goncalves A,Amiot MJ

更新日期：2017-11-01 00:00:00