Colon cancer therapy: new perspectives of nutritional manipulations using polyunsaturated fatty acids.

abstract：PURPOSE OF REVIEW:Leucine does not only serve as a substrate for protein synthesis but is also recognized as a potent signal nutrient that regulates protein metabolism. Accordingly, leucine supplementation has been suggested to develop muscle mass or prevent protein loss in several conditions characterized by muscle pr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Balage M,Dardevet D

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the recent findings on metabolic monitoring and possible beneficial effects of an adequate nutrition therapy, based on indirect calorimetry as the golden standard to predict energy expenditure. RECENT FINDINGS:in the last decades, major steps are taken in the field of metabolism and nutriti...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： De Waele E,Honoré PM,Malbrain MLNG

更新日期：2018-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Obese individuals have impaired respiratory function relative to their normal-weight counterparts. Despite these negative effects, obesity is paradoxically associated with better survival in individuals with chronic obstructive pulmonary disease (COPD). The purpose of this review is to describe this '...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Guenette JA,Jensen D,O'Donnell DE

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The increase in obesity in developed societies drives interest in the interplay of energy intake, metabolic energy expenditure, and body energy stores. A better understanding of energy management in physically active and undernourished humans should help guide strategies to manage obesity safely and e...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hoyt RW,Friedl KE

更新日期：2006-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This article is intended to briefly overview available methodological approaches for the study of regional metabolism in man in vivo, and to summarize recent advances in this field of research. RECENT FINDINGS:Several methods have been developed and currently allow for the qualitative and quantitativ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Magkos F,Sidossis LS

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to emphasize the importance of malnutrition in frail institutionalized elderly and discuss recent interventions that have been shown to decrease its prevalence. RECENT FINDINGS:A Medline search was conducted from 1968 to 2007 under the search terms aging, nutrition, and nur...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Labossiere R,Bernard MA

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:There is increasing clinical and pathophysiological evidence that a premature aging process is involved in the pathogenesis of systemic complications of many chronic organ diseases, which result in analogous phenotypes, including premature vascular aging, osteoporosis and muscle wasting. Novel develop...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kooman JP,Shiels PG,Stenvinkel P

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular endothelial cells control vascular smooth muscle tone via the release of nitric oxide. Following adverse circulatory conditions, namely trauma and hemorrhage, endothelial cell dysfunction occurs, leading to a decrease in the release of endothelium-derived nitric oxide, which contributes to fu...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Loehe F,Bruns CJ,Nitsch SM,Angele MK

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition is highly prevalent in hospitalized patients. Despite this, it is not routinely assessed in most hospitals worldwide. One of the reasons that might explain this fact is that there is no gold-standard nutritional assessment tool, and much has been written advocating this or that technique....

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Waitzberg DL,Correia MI

更新日期：2003-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The loss of skeletal muscle with injury or critical illness can be dramatic. This review emphasizes the importance of skeletal muscle as a metabolic reserve. Changes in protein metabolism with bed rest alone and during physiological stress are discussed. Nutritional and hormonal interventions that ame...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ferrando AA,Paddon-Jones D,Wolfe RR

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the recent advances in our understanding of fatty acids and lipids in paediatric nonalcoholic fatty liver disease (NAFLD) and their future implications. RECENT FINDINGS:Data have been accumulated to suggest that ceramides are the main drivers of hepatic insulin resistance in NAFLD, and in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Mann JP,Feldstein AE,Nobili V

更新日期：2017-03-01 00:00:00

abstract：:Arginine is a non-essential amino acid in mammals as judged from nitrogen balance study. Citrulline is synthesized from glutamate in the small intestine, whilst kidneys and some other tissues convert citrulline to arginine. Ornithine transcarbamylase and carbamylphosphate synthetase are expressed in liver and small in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wakabayashi Y

更新日期：1998-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight the recent evicence for optimal protein intake and protein supplementation in older adults. A special focus has been placed on the effects on muscle protein synthesis, strength and overall performance in this population. RECENT FINDINGS:Although for older adults, some additional evidence...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Bauer JM,Diekmann R

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of the present review is to provide insights into the future therapeutic approaches to cancer-related muscle wasting that flow from the progressive knowledge of mechanisms regulating muscle mass in health and disease. RECENT FINDINGS:Cancer cachexia is a severely debilitating and life-threate...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Muscaritoli M,Bossola M,Bellantone R,Rossi Fanelli F

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle metabolic energy, needed to maintain contractile activity, is mainly obtained from glucose and long-chain fatty acids. Recent studies have revealed a remarkable parallel between the regulation of uptake of glucose and fatty acids by muscle, in that each is mediated by sarcolemmal trans...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Glatz JF,Bonen A,Luiken JJ

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The speed of dietary protein digestion influences postprandial amino acid availability which is crucial for improving altered anabolic response of skeletal muscle one feature of sarcopenia during aging. RECENT FINDINGS:By analogy with carbohydrate and in reference to their absorption rate, dietary pr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Boirie Y,Guillet C

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This article provides an overview of the most recent molecular and clinical outcomes of studies that investigate the effect of weight loss and calorie restriction on carbohydrate metabolism, obtained either by dieting or bariatric surgery. It will focus on aspects of carbohydrate metabolism related to...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Manco M,Mingrone G

更新日期：2005-07-01 00:00:00

abstract：:Studies of many different rodent models of muscle wasting have indicated that accelerated proteolysis via the ubiquitin-proteasome pathway is the principal cause of muscle atrophy induced by fasting, cancer cachexia, metabolic acidosis, denervation, disuse, diabetes, sepsis, burns, hyperthyroidism and excess glucocort...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Jagoe RT,Goldberg AL

更新日期：2001-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze current evidence for the posology and pharmacokinetics of selenium supplementation in the critically ill. RECENT FINDINGS:Antioxidants and especially high-dose parenteral selenium may be associated with a significant reduction in mortality among critically ill patients with systemic inflam...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Manzanares W,Hardy G

更新日期：2009-05-01 00:00:00

abstract：:Plant sterols have recently been recommended by the National Cholesterol Education Panel for use with the more traditional approaches of limiting saturated fat and cholesterol intakes, maintaining a healthy body weight and engaging in regular exercise, as a non-pharmacological approach to reduce low-density lipoprotei...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lichtenstein AH

更新日期：2002-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity is associated with low-grade chronic inflammation in adipose tissue. This review presents an update on human and rodent studies analyzing the nature of fat-infiltrating immune cells, the time course of adipose tissue infiltration and underlying mechanisms. RECENT FINDINGS:Intensive studies in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sell H,Eckel J

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:A fundamental advance in our understanding of endocrine control of energy balance and body weight came with the discovery of the adipocyte-derived hormone leptin. The leptin pathway appeared to be the long-sought peripheral signal pathway from the adipose tissue to the brain involved in the regulation...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hukshorn CJ,Saris WH

更新日期：2004-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The obesity paradox is a highly controversial concept that may be attributed to methodological limitations related to its identification. One of the primary concerns is the use of BMI to define obesity. This index does not differentiate lean versus adipose tissue compartments (i.e. body composition) c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Prado CM,Gonzalez MC,Heymsfield SB

更新日期：2015-11-01 00:00:00

abstract：:The nuclear factor kappa B family of inducible transcription factors regulates the expression of many genes. Nuclear factor kappa B has been implicated in autoimmune and inflammatory diseases, infection, cell survival, and cell transformation with subsequent promotion of cancer. In this review, we summarize features o...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Holmes-McNary M

更新日期：2002-05-01 00:00:00

abstract：:Milk is the only biomaterial that evolved under the Darwinian selective pressure to nourish growing mammals. The purpose of this article is to review the scientific research that is using new techniques of integrating biological sequence, structure and function, to understand the innovative biology underlying the prod...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： German JB,Dillard CJ,Ward RE

更新日期：2002-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this overview is to highlight the multiple ways in which oxidative stress could be exacerbating muscle wasting. Understanding these interactions in vivo will assist in identifying opportunities for more targeted therapies to reduce skeletal muscle wasting. RECENT FINDINGS:There are many ex...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Arthur PG,Grounds MD,Shavlakadze T

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Objective and subjective methods are used to assess nutritional status. They are used as diagnostic, prognostic and response tools. It is still controversial which of them is more suitable for each situation and what they are really assessing. The most recent findings about these methods will be discu...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Barbosa-Silva MC

更新日期：2008-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the relationship between nutritional therapies and the intestinal microbiome of critically ill patients. RECENT FINDINGS:The intestinal microbiome of the critically ill displays a near complete loss of health-promoting microbiota with overgrowth of virulent healthcare-associated...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Krezalek MA,Yeh A,Alverdy JC,Morowitz M

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective of this review has been to analyse and compare the causes, incidence, severity and treatment of gastrointestinal complications in critically ill children and adults. RECENT FINDINGS:The incidence of gastrointestinal complications in critically ill patients published in the literature is...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： López-Herce J

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:A compromised autophagy is associated with the onset of obesity, type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative diseases. Our aim is to review the potential role of ghrelin, a gut hormone involved in energy homeostasis, in the regulation of autophagy. RECENT F...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ezquerro S,Frühbeck G,Rodríguez A

更新日期：2017-09-01 00:00:00