Amino acid metabolism in liver disease.

abstract：PURPOSE OF REVIEW:Both dietary and nondietary factors contribute to iron deficiency, the most common nutritional deficiency worldwide. Identifying dietary factors associated with iron deficiency is challenging due to the number of components in food affecting iron absorption. This review describes recent advances in di...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Beck KL,Heath AL

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Ketone body metabolism is a dynamic and integrated metabolic node in human physiology, whose roles include but extend beyond alternative fuel provision during carbohydrate restriction. Here we discuss the most recent observations suggesting that ketosis coordinates cellular function via epigenomic reg...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ruan HB,Crawford PA

更新日期：2018-07-01 00:00:00

abstract：PURPOSE OF REVIEW:In recent years, the lower costs of arrays and sequencing technologies, and the better availability of data from genome-wide association studies (GWASs) have led to more reports on genetic factors that are associated with bone health. However, there remains the need for a summary of the newly identifi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lovšin N,Zupan J,Marc J

更新日期：2018-07-01 00:00:00

abstract：:Drug-nutrient interactions have been recognized for decades. It is known that improper management of some of these interactions may lead to therapeutic failure or cause serious adverse effects to the patients. While most of the known drug-nutrient interactions involve changes in oral bioavailabilities and absorption o...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Chan LN

更新日期：2002-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine the stability and compatibility of histamine H2-receptor antagonists in parenteral nutrition admixtures in order to provide well tolerated and effective therapy. RECENT FINDINGS:Many stability investigations were carried out before 2005, but no critical appraisal of published data has been...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Puzovic M,Hardy G

更新日期：2007-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Growth hormone is a powerful anabolic hormone necessary for normal growth, but its importance in maintaining the cellular and protein mass in adult life is still unclear. However, it is viewed as a drug capable of combating the tissue loss and some metabolic derangements of aging. Growth hormone exces...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Battezzati A,Bertoli S

更新日期：2005-01-01 00:00:00

abstract：PURPOSE OF REVIEW:High-fat diets lead to obesity and increase the risk of developing insulin resistance and type 2 diabetes. Adipose tissue and skeletal muscle act as endocrine organs, and produce various cytokines that can potentially alter peripheral insulin sensitivity. The purpose of the present review is to briefl...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Stefanyk LE,Dyck DJ

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The diagnosis of aspiration and its origin in patients on enteral tube feeding is challenging to the physician and provides an important means to prevent pneumonia. This review examines the most recent studies and developments in the field with an approach to the technical aspects of diagnostic method...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Gomes GF,Campos AC,Pisani JC,Macedo ED,Vieira MC

更新日期：2004-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle metabolic energy, needed to maintain contractile activity, is mainly obtained from glucose and long-chain fatty acids. Recent studies have revealed a remarkable parallel between the regulation of uptake of glucose and fatty acids by muscle, in that each is mediated by sarcolemmal trans...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Glatz JF,Bonen A,Luiken JJ

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses upon the biology and metabolism of a trace component in foods called nicotinamide riboside. Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD), and is a source of Vitamin B3. Evidence indicates that nicotinamide riboside has unique properties as a Vitam...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Chi Y,Sauve AA

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review depicts recent developments concerning the role of the liver in control of carbohydrate and lipid utilization from ingestion to storage; it covers the liver's influence on food intake, post-absorptive nutrient metabolism and body weight. The mechanisms involved have implications for the pa...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Langhans W

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Lipidomic profiling of biological samples is increasing in nutritional research applications. 'Lipidomic analyses' however can be quite variable in specific methods and the type of information about the specific lipids that is revealed. The lack of defined and simple terminology to describe aspects of...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Aristizabal Henao JJ,Bradley RM,Duncan RE,Stark KD

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight the recent evicence for optimal protein intake and protein supplementation in older adults. A special focus has been placed on the effects on muscle protein synthesis, strength and overall performance in this population. RECENT FINDINGS:Although for older adults, some additional evidence...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Bauer JM,Diekmann R

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:L-Arginine is the precursor for nitric oxide synthesis. In the brain, nitric oxide acts as a neurotransmitter; in the immune system, nitric oxide acts as a mediator of host defense; in the cardiovascular system, nitric oxide mediates the protective effects of the intact endothelium, acting as an endog...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Böger RH

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the recent advances in our understanding of fatty acids and lipids in paediatric nonalcoholic fatty liver disease (NAFLD) and their future implications. RECENT FINDINGS:Data have been accumulated to suggest that ceramides are the main drivers of hepatic insulin resistance in NAFLD, and in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Mann JP,Feldstein AE,Nobili V

更新日期：2017-03-01 00:00:00

abstract：:Laboratory methods for the measurement of micronutrients are usually based upon determinations in the peripheral blood. Most are relatively insensitive, but can screen for impending acute deficiency or toxicity. The metabolic responses to disease, injury and infection may alter the laboratory findings independently of...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fell GS,Talwar D

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent epidemiologic and intervention studies addressing the impact of hyperglycemia on morbidity and mortality in critically ill patients. It also discusses a growing body of literature examining why elevated blood glucose occurs in hospitalized patients without previously recogn...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Falciglia M

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide guidance for investigators who are new to the field of DNA methylation analysis. RECENT FINDINGS:Epigenetics is the study of mitotically heritable alterations in gene expression potential that are not mediated by changes in DNA sequence. Recently, it has become clear that nutrition can aff...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Shen L,Waterland RA

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The main aim of this review is to summarize current knowledge of tumor protein p53-inducible nuclear protein 2 (TP53INP2) function and its role in skeletal muscle proteostasis. RECENT FINDINGS:Autophagy is directly involved in the regulation of skeletal muscle mass. Thus, excessive autophagy is assoc...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sala D,Zorzano A

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of the present review is to provide insights into the future therapeutic approaches to cancer-related muscle wasting that flow from the progressive knowledge of mechanisms regulating muscle mass in health and disease. RECENT FINDINGS:Cancer cachexia is a severely debilitating and life-threate...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Muscaritoli M,Bossola M,Bellantone R,Rossi Fanelli F

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Preventing unintentional weight and muscle loss is of crucial importance to maintain the condition and well-being of patients with cancer, improve treatment response and tolerance, and prolong survival. Anabolic resistance might explain why some cancer patients do not respond to nutritional interventi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Engelen MP,van der Meij BS,Deutz NE

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Infection and sepsis remain major challenges in the critically ill. How nutritional therapy can effect real clinical outcomes is not easily apparent from the clinical data. Despite reducing infectious incidence, many studies show little difference in meaningful clinical outcomes. RECENT FINDINGS:Conf...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Griffiths RD

更新日期：2003-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to examine the concept of anorexia of aging, including its complex pathophysiology and the multifaceted interventions required to prevent adverse health consequences from this geriatric syndrome. RECENT FINDINGS:Anorexia of aging is extremely common, occurring in up to 3...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sanford AM

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective of this review has been to analyse and compare the causes, incidence, severity and treatment of gastrointestinal complications in critically ill children and adults. RECENT FINDINGS:The incidence of gastrointestinal complications in critically ill patients published in the literature is...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： López-Herce J

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle and lean body mass may be vital to prognosis and functional recovery in chronic and acute illness, particularly in conditions in which muscle atrophy is prevalent. Ultrasound provides a precise and expedient method to measure muscle mass and changes in skeletal muscle at the bedside. ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Mourtzakis M,Wischmeyer P

更新日期：2014-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To characterize methods evaluating and to summarize studies linking various serum 25-hydroxyvitamin D [25(OH)D] concentrations with health status. RECENT FINDINGS:Elucidation of the cell-biologic mechanism of vitamin D action, and numerous clinical trials and observational studies relating vitamin D ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Heaney RP

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review aims to address the role of adipose tissue oxygen partial pressure (PO2) in the metabolic and endocrine derangements in conditions characterized by insulin resistance. RECENT FINDINGS:The balance between adipose tissue oxygen supply and its metabolic rate seems to determine adipose...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Goossens GH,Blaak EE

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Preoperative nutritional support in severely malnourished patients decreases complications after major surgery. This review summarizes previous studies on head and neck cancer patients undergoing surgery, and offers recommendations on preoperative nutritional support based on the literature and our ex...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Bertrand PC,Piquet MA,Bordier I,Monnier P,Roulet M

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Muscular mitochondrial dysfunction, leading to the accumulation of fat in skeletal muscle, has been proposed to be involved in the development of type 2 diabetes mellitus. Here, we review human studies that investigated various aspects of mitochondrial function in relation to muscular insulin sensitiv...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Schrauwen-Hinderling VB,Roden M,Kooi ME,Hesselink MK,Schrauwen P

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Improving our understanding of factors driving fat gain in young children should increase our ability to manage the rising problem of obesity. Accordingly, studies associating timing of adiposity rebound with later obesity are reviewed. RECENT FINDINGS:Investigations in many countries have confirmed ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Taylor RW,Grant AM,Goulding A,Williams SM

更新日期：2005-11-01 00:00:00