Assessing vitamin D status.

Abstract:

PURPOSE OF REVIEW:To characterize methods evaluating and to summarize studies linking various serum 25-hydroxyvitamin D [25(OH)D] concentrations with health status. RECENT FINDINGS:Elucidation of the cell-biologic mechanism of vitamin D action, and numerous clinical trials and observational studies relating vitamin D status to health and disease. CONCLUSION:The distinction between deficiency and insufficiency is not useful or necessary. Serum 25(OH)D values below 120  nmol/l (48  ng/ml) are associated with preventable disease and are therefore indicative of deficiency. The upper limit of the normal range can be set at 225  nmol/l (90  ng/ml), although toxicity is rare below 500  nmol/l (200  ng/ml).

authors

Heaney RP

doi

10.1097/MCO.0b013e328348ed85

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

440-4

issue

5

eissn

1363-1950

issn

1473-6519

pii

00075197-201109000-00006

journal_volume

14

pub_type

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